[go: up one dir, main page]

WO2009050447A2 - Produits pour la peau à base d'eau - Google Patents

Produits pour la peau à base d'eau Download PDF

Info

Publication number
WO2009050447A2
WO2009050447A2 PCT/GB2008/003485 GB2008003485W WO2009050447A2 WO 2009050447 A2 WO2009050447 A2 WO 2009050447A2 GB 2008003485 W GB2008003485 W GB 2008003485W WO 2009050447 A2 WO2009050447 A2 WO 2009050447A2
Authority
WO
WIPO (PCT)
Prior art keywords
skin
sanitiser
gel
antimicrobial agent
agent
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Ceased
Application number
PCT/GB2008/003485
Other languages
English (en)
Other versions
WO2009050447A3 (fr
Inventor
Pravin Battarcharya
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
MAGENTA TRADING Ltd
Original Assignee
MAGENTA TRADING Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by MAGENTA TRADING Ltd filed Critical MAGENTA TRADING Ltd
Publication of WO2009050447A2 publication Critical patent/WO2009050447A2/fr
Publication of WO2009050447A3 publication Critical patent/WO2009050447A3/fr
Anticipated expiration legal-status Critical
Priority to ZA2010/03270A priority Critical patent/ZA201003270B/en
Ceased legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
    • A01N25/00—Biocides, pest repellants or attractants, or plant growth regulators, characterised by their forms, or by their non-active ingredients or by their methods of application, e.g. seed treatment or sequential application; Substances for reducing the noxious effect of the active ingredients to organisms other than pests
    • A01N25/02—Biocides, pest repellants or attractants, or plant growth regulators, characterised by their forms, or by their non-active ingredients or by their methods of application, e.g. seed treatment or sequential application; Substances for reducing the noxious effect of the active ingredients to organisms other than pests containing liquids as carriers, diluents or solvents
    • A01N25/04—Dispersions, emulsions, suspoemulsions, suspension concentrates or gels
    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
    • A01N25/00—Biocides, pest repellants or attractants, or plant growth regulators, characterised by their forms, or by their non-active ingredients or by their methods of application, e.g. seed treatment or sequential application; Substances for reducing the noxious effect of the active ingredients to organisms other than pests
    • A01N25/16—Foams
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/02—Cosmetics or similar toiletry preparations characterised by special physical form
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/02—Cosmetics or similar toiletry preparations characterised by special physical form
    • A61K8/04—Dispersions; Emulsions
    • A61K8/042—Gels
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/02—Cosmetics or similar toiletry preparations characterised by special physical form
    • A61K8/04—Dispersions; Emulsions
    • A61K8/046—Aerosols; Foams
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/33—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing oxygen
    • A61K8/34—Alcohols
    • A61K8/345—Alcohols containing more than one hydroxy group
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q17/00—Barrier preparations; Preparations brought into direct contact with the skin for affording protection against external influences, e.g. sunlight, X-rays or other harmful rays, corrosive materials, bacteria or insect stings
    • A61Q17/005—Antimicrobial preparations
    • C—CHEMISTRY; METALLURGY
    • C11—ANIMAL OR VEGETABLE OILS, FATS, FATTY SUBSTANCES OR WAXES; FATTY ACIDS THEREFROM; DETERGENTS; CANDLES
    • C11D—DETERGENT COMPOSITIONS; USE OF SINGLE SUBSTANCES AS DETERGENTS; SOAP OR SOAP-MAKING; RESIN SOAPS; RECOVERY OF GLYCEROL
    • C11D17/00—Detergent materials or soaps characterised by their shape or physical properties
    • C11D17/0008—Detergent materials or soaps characterised by their shape or physical properties aqueous liquid non soap compositions
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2800/00—Properties of cosmetic compositions or active ingredients thereof or formulation aids used therein and process related aspects
    • A61K2800/80—Process related aspects concerning the preparation of the cosmetic composition or the storage or application thereof
    • A61K2800/82—Preparation or application process involves sonication or ultrasonication
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0034—Urogenital system, e.g. vagina, uterus, cervix, penis, scrotum, urethra, bladder; Personal lubricants

Definitions

  • This application relates to water-based products for use on skin.
  • it relates to a skin sanitiser and to a lubricating gel.
  • Alcohol dries the skin, and so repeated use can lead to skin damage. Whilst its evaporation at body temperature leads to quick drying, it also means it can have evaporated before the user has been able to rub it into all parts of their hand. Alcohol is also highly flammable, which could have dangerous consequences in the case of a spill. Alcohol-containing products may also be problematic for strict members of religions such as Islam.
  • US 2003/0139307 discloses a sanitising hand cleanser intended to address some of the problems relating to high alcohol content.
  • the disclosed cleanser nevertheless contains an effective amount of alcohol to produce a reduction in micro-organisms and is not water- based.
  • the disclosed cleanser thus suffers from one or more of the above disadvantages associated with alcohol-containing sanitisers.
  • US 2004/0219227 relates to hydroalcoholic gel formulations for skin disinfection.
  • the disclosed formulations generally include a high percentage of ethanol or propan-2-ol. Whilst this document discloses an antiseptic aqueous formulation, this still contains 2% stearyl alcohol. The disclosed formulations thus suffer from at least one of the above problems associated with alcohol-containing skin sanitisers.
  • US 6,627,207 discloses a water-based gel-type skin sanitiser, having a low alcohol content. It discloses gel-type compositions containing from 5.9 to 31.1% by weight ethanol. Again, as the disclosed compositions contain ethanol, at least one of the above problems relating to alcohol-containing skin sanitisers applies.
  • compositions including an active antibacterial agent, a surfactant, a hydrotrope, a hydric solvent (which may be an alcohol), at least one of a skin care agent, a foam stabiliser (which may be an alcohol) or a humectant, and water.
  • a surfactant which may be an alcohol
  • a hydrotrope which may be an alcohol
  • a hydric solvent which may be an alcohol
  • a foam stabiliser which may be an alcohol
  • humectant a humectant
  • US 7, 192,601 discloses an antimicrobial and sporicidal composition that may be used as a topical skin care formulation.
  • the composition may include ethanol or propan-2-ol as an antibacterial agent.
  • Monohydric alcohols may also be used as emulsifiers/surfactants.
  • US 2007/0071537 discloses a sanitising wipe containing an antimicrobial liquid cleansing formulation.
  • the formulation may be diluted with alcohol.
  • the sanitiser includes an antimicrobial agent, a spreading agent (or surfactant), a humectant, a thickener, a preservative, a fragrance and water. It is preferably substantially free of alcohol, but may contain up to 1% by weight of alcohol.
  • WO 2006/092581 discloses a lubricating composition prepared primarily from natural ingredients.
  • US 2006/0127316 discloses a lubricant ultrasound transmission medium that does not contain water.
  • the medium may be prepared in alcohol.
  • WO 2007/038855 discloses an antimicrobial gel that may be used as an ultrasound transmission medium.
  • the gel includes a solvent (which may be water), a thickener (which may be hydroxyethyl cellulose) and an antimicrobial agent. It may further include xamtham gum and/or propylene glycol.
  • a water-based skin sanitiser that is free of alcohol, wherein the skin sanitiser is a gel or a mousse.
  • the skin sanitiser preferably includes: a skin moisturiser; an antimicrobial agent; and a foaming aid or a gelling ingredient.
  • the skin moisturiser is a skin humectant and/or a skin soothant and/or a skin softener.
  • the skin sanitiser may further include any or all of: a surfactant, a pH adjuster, a pH balancer, a colorant, a preservative.
  • the skin sanitiser may include a plant-based ingredient such as aloe vera; a diol such as propylene glycol or ethylene glycol; PEG-8 dimethicone, PEG-8 ricinoleate, polyquaternium 57; and/or a polysorbate such as polysorbate 20.
  • a plant-based ingredient such as aloe vera
  • a diol such as propylene glycol or ethylene glycol
  • PEG-8 dimethicone PEG-8 ricinoleate
  • polyquaternium 57 polyquaternium 57
  • a polysorbate such as polysorbate 20.
  • the antimicrobial agent may be an antibacterial agent such as cetrimide, chlorhexidine digluconate, benzalkonium chloride, and/or triclosan.
  • the antimicrobial agent may be provided in an amount of about 0.495-0.88%. In certain embodiments it is provided in an amount of about 0.495-0.605% or about 0.72%-0.88%.
  • the gelling agent may be an acrylates/C 10-30 alkyl acrylates cfosspolymer.
  • the skin sanitiser is a gel and includes a skin soothant, a skin humectant, a gelling agent, an antimicrobial agent, a surfactant, a pH adjuster, a pH balancer and a colourant.
  • the gel includes about 3.6-4.4% skin soothant, about 18-22% skin humectant, about 0.45-0.55% gelling ingredient, about 0.495-0.88% antimicrobial agent, about 1.35- 1.65% surfactant, about 0.027-0.033% pH adjuster, about 0.72-0.88% triethanolamine, and/or about 0.0009-0.0011% colourant.
  • the gel includes about 4% skin soothant about 20% skin humectant, about 0.5% gelling ingredient, about 0.8% antimicrobial agent, about 1.5% surfactant, about 0.03% pH adjuster; about 0.8% pH balancer and/or about 0.001% colourant.
  • the skin sanitiser when it is a sanitising mousse, it may include a foaming aid, which may also act as an antimicrobial agent, such as cetrimide and/or chlorhexidine digluconate.
  • a foaming aid which may also act as an antimicrobial agent, such as cetrimide and/or chlorhexidine digluconate.
  • the skin sanitiser is a mousse and includes a skin soothant, a skin humectant, a skin moisturiser or softener, an antimicrobial agent, a foaming aid, a preservative and a pH adjuster.
  • the mousse includes about 1.8-2.2% skin soothant, about 4.5-5.5% skin humectant, about 0.63-0.77% skin moisturiser or softener; about 0.405-0.495% foaming aid/antimicrobial agent; about 0.18-0.22% preservative; about 0.18-0.22% pH adjuster, and/or about 0.09-0.11% antimicrobial agent.
  • the mousse includes about 2% skin soothant, about 5% skin humectant, about 0.7% skin moisturiser or softener, about 0.25% foaming aid/antimicrobial agent, about 0.2% preservative, about 0.2% pH adjuster, and/or about 0.1% antimicrobial agent.
  • a water-based ultrasound transmitting lubricating gel that is free of alcohol.
  • the lubricating gel preferably includes: a skin moisturiser; a gelling agent; and a lubricant.
  • the skin moisturiser is a skin humectant.
  • the lubricating gel may further include any or all of a thickening agent, a preservative, a pH adjuster.
  • the lubricant also acts as a thickening agent.
  • the lubricating gel may include a diol such as propylene glycol or ethylene glycol; a cellulose ether such as hydroxyethylcellulose; a polysaccharide such as xantham gum, a paraben such as methylparaben, ethylparaben, propylparaben or butylparaben; and/or disodium EDTA.
  • a diol such as propylene glycol or ethylene glycol
  • a cellulose ether such as hydroxyethylcellulose
  • a polysaccharide such as xantham gum
  • a paraben such as methylparaben, ethylparaben, propylparaben or butylparaben
  • disodium EDTA disodium EDTA
  • the lubricating gel includes about 18-22% skin humectant, about 0.9-1.1% lubricant; about 0.09-0.11% gelling agent, about 0.36-0.44% preservative; and/or about 0.09-0.11% pH adjuster.
  • the lubricating gel includes about 20% skin humectant; about 1% lubricant; about 0.1% gelling agent; about 0.4% preservative, and/or about 0.1% pH adj uster.
  • Example 1 Sanitising Gel
  • a preferred sanitising gel includes the following ingredients 4.00% aloe barbadensis (1Ox strength) (obtainable as USA Best 10-1 Aloe VeraTM from Paroxite), 20.00% propylene glycol; 0.50% acrylates/C 10-30 alkyl acrylates cross polymer (CARBOPOL® Ultrez 20 polymer from Noveon); 0.25% cetrimide (Surfac Cetrimide BP Powder obtainable from Surfachem); 0.30% chlorhexidine digluconate (Surfac CHX20 obtainable from Surfachem); 1.50% polysorbate 20 (Surfacare T20 available from Surfachem Group Limited); 0.03% disodium EDTA; 0.80% triethanolamine (Surfac Triethanolamine standard available from Surfachem Group Limited); and 0.001% CI 42090 (FDC Blue No. 1) (from Simpsons (UK) Ltd) dissolved in UV irradiated water.
  • aloe barbadensis (1Ox strength) (obtainable as USA
  • the gel is made by mixing 95% of the water and the disodium EDTA in a suitable first vessel until the disodium EDTA has dissolved. Subsequently, whilst mixing, the acrylates/C 10-30 alkyl acrylates crosspolymer is added. Mixing is continued until fully wetted. The next step is to add (with mixing) the aloe barbadensis, the propylene glycol, and the CI 42090 and mix well. In a separate second vessel, a premix of the cetrimide, and 5% of the total required water is formed. This is mixed until there is no visible solid. The chlorhexidine digluconate is then added to the second vessel and mixed well, followed by the polysorbate 20, which is mixed well.
  • the mixer in the main vessel is turned off, thereby allowing the mixture therein to stand for 30 minutes. After this time, the triethanolamine is added to the first vessel and mixed until fully gelled. The pH should be adjusted to approximately 8. With slow stirring, the premix in the second vessel is added to the first vessel by slowly pouring over a period of 10 to 20 minutes.
  • the resulting gel is a clear pale blue viscous gel having no characteristic odour. Its specific gravity is 1.01 ⁇ 0.15 at 25 0 C and its viscosity is 20,000 cps ⁇ 3,000 cps. The pH at 25 0 C is between 7.70 and 8.50. Fewer than 100 cfu/ml were identified in microbiological tests, with a complete absence of pathogens.
  • the gel is subsequently packaged in a 50ml PVC inverted bottle that can clip onto a pocket or belt.
  • the sanitising gel can be used in any environment where quick and effective skin sanitisation is required. The user simply squirts some of the gel onto their hands and rubs it all over. Within 30 seconds to one minute the gel is absorbed; there is therefore no need to rinse.
  • the sanitising gel has excellent sanitisation properties by inclusion of the antibacterial agents cetrimide and chlorhexidine digluconate. Furthermore, it is beneficial to the skin of the user by inclusion of moisturisation ingredients and skin softening ingredients.
  • Aloe barbadensis is a plant extract having beneficial skin soothing properties.
  • Propylene glycol acts as a skin humectant, and advantageously allows the product to have a longer lasting effect.
  • Polysorbate 20 acts as a surfactant.
  • it also acts as a fragrance solubiliser and stabiliser, it acts as a lubricator and has a soothing effect on the skin.
  • Disodium EDTA allows the pH of the product to be adjusted to the pH of the skin (approximately 6).
  • Triethanolamine acts as a pH balancer.
  • This product fulfils the requirements of BS EN 1276:1997 (suspension test) and BS EN 1500:1997 (human volunteer) despite the absence of alcohol.
  • the amount of cetrimide is 0.5%.
  • benzalkonium chloride is used as an antibacterial agent instead of cetrimide.
  • the amount of benzalkonium chloride is 0.5%.
  • a preferred sanitising mousse contains 2.00% aloe barbadensis (1Ox strength) (for example, obtainable as USA Best 10-1 Aloe VeraTM from Paroxite); 5.00% propylene glycol; 0.70% PEG-8 dimethicone, PEG-8 ricinoleate, polyquaternium 57 (available as Zenicone XQTM from Zenitech®), 0.25% cetrimide (available from Surfachem Group Ltd as Surfac Cetrimide BP Powder), 0.20% chlorhexidine digluconate (available as Surfac CHX20 from Surfachem Group Ltd); 0.20% citric acid; 0.20% disodium EDTA and; 0.10% triclosan in UV irradiated water.
  • 1Ox strength for example, obtainable as USA Best 10-1 Aloe VeraTM from Paroxite
  • propylene glycol 0.70% PEG-8 dimethicone, PEG-8 ricinoleate, polyquaternium 57 (available as Zenicone
  • the mousse is made by, in a suitable first vessel, premixing 10% of the water with the disodium EDTA and warming the mixture until the disodium EDTA has dissolved. The remainder of the water is added to a second suitable vessel, then, with mixing, the disodium EDTA solution, the aloe vera (1Ox), the cetrimide, the chlorhexidine digluconate, the PEG-8 dimethicone, PEG-8 ricinoleate polyquaternium 57 and the citric acid are added and mixed until all of the solids have been solubilised.
  • the propylene glycol and the triclosan are warmed and mixed until solubilised. The propylene glycol/triclosan mix is then slowly poured into the main mixture in the second vessel whilst mixing.
  • the liquid is packaged in a 50ml cylindrical bottle having a pump-action dispenser.
  • the user squirts an appropriate amount of mousse onto their hands and rubs it in to provide effective sanitization.
  • the mousse dries; there is therefore no requirement for rising.
  • the sanitising mousse has excellent sanitisation properties due to the inclusion of the antibacterial agents cetrimide, chlorhexidine digluconate and triclosan.
  • cetrimide and chlorohexidine digluconate also act as foaming aids.
  • the mousse also contains ingredients beneficial to the user's skin.
  • Aloe barbadensis is a plant extract having skin soothing properties.
  • Propylene glycol is not only a skin humectant, but advantageously allows the product to have a longer lasting effect.
  • PEG-8 dimethicone, PEG-8 ricinoleate, polyquaternium 57 is a high density polymer with excellent moisturisation and skin softening properties, which softens and moisturises the skin on use.
  • the disodium EDTA can be used to adjust the pH of the product to the pH of the skin (approximately 6).
  • the citric acid acts as a cleaning agent, a preservative and an antioxidant.
  • the mousse is not an aerosol and so there is no risk of any aerosol propellant interfering with remaining ingredients.
  • the mouse has undergone microbiological testing and this product fulfils the requirements of BS EN 1276:1997 (suspension test) and BS EN 1500:1997 (human volunteer) despite the absence of alcohol.
  • the amount of cetrimide is 0.5%.
  • benzalkonium chloride is used as an antibacterial agent instead of cetrimide.
  • the amount of benzalkonium chloride is 0.5%.
  • a lubricating gel that can be used for ultrasound transmission preferably contains 20.0% propylene glycol; 1.0% hydroxyethylcellulose (for example, that can be obtained as Natrosol® 250 HHR from Crestchem); 0.1% xanthan gum (such as can be obtained as Keltrol® CGRD from CPKelco); 0.2% methylparaben; 0.2% imidazolidinyl urea (such that as that which can be obtained as Surfacare PC GM 115 from Surfachem) ; and 0.1% disodium EDTA in UV irradiated water.
  • propylene glycol 1.0% hydroxyethylcellulose (for example, that can be obtained as Natrosol® 250 HHR from Crestchem); 0.1% xanthan gum (such as can be obtained as Keltrol® CGRD from CPKelco); 0.2% methylparaben; 0.2% imidazolidinyl urea (such that as that which can be obtained as Surfacare PC GM 115 from Surfachem)
  • the water is added to a first suitable vessel, and with a mixer the imidazolidinyl urea, disodium EDTA are added and mixed until there are no visible solids (this takes approximately 30 minutes).
  • a separate second suitable vessel the methylparaben is dissolved in the propylene glycol by gently warming to increase the rate of solubility.
  • the methylparaben/propylene glycol mixture is then added to the imidazolidinyl urea/disodium EDTA solution and mixed well.
  • the hydroxyethylcellulose and xanthan gum are added with mixing; mixing is continued until the gum and the cellulose are fully hydrated (this takes at least three hours).
  • the resulting product is a clear, colourless, flowable gel having no characteristic odour. Its specific gravity is 1.01 ⁇ 0.15 at 25 0 C and it has a viscosity of 25,000 cps ⁇ 3,000 cps at 25 0 C. The pH of the gel at 25 0 C is 6.00 ⁇ 0.60. Fewer than 100 cfu/ml were found in microbiological tests, and there was a complete absence of pathogens.
  • the gel is packaged into 8ml single use sachets.
  • the desired amount of product is applied onto the area required and is gently massaged over the area. It is particularly envisaged for use during ultrasound examination (both external and internal).
  • lubricating gel can be used during ultrasound examination and it has high lubricity. It contains no alcohol or fragrance thereby reducing the risk of irritating the skin of the person undergoing the procedure. The gel does not dry the skin, and it is also oil free.
  • Hydroxyethylcellulose is the main thickening agent, which advantageously has lubricating properties.
  • xanthan gum is a naturally derived gelling agent, which also improves the lubricity of the product.
  • Propylene glycol acts as a skin humectant, and advantageously allows the product to have a longer lasting effect.
  • Methylparaben and imidazolidinyl urea contribute to the preservative properties of the product.
  • Disodium EDTA allows the pH of product to be adjusted to that of the skin (approximately 6.0). It also has sequestering properties.

Landscapes

  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • Engineering & Computer Science (AREA)
  • Wood Science & Technology (AREA)
  • Dispersion Chemistry (AREA)
  • Birds (AREA)
  • Epidemiology (AREA)
  • Dentistry (AREA)
  • Zoology (AREA)
  • Agronomy & Crop Science (AREA)
  • Pest Control & Pesticides (AREA)
  • Plant Pathology (AREA)
  • Toxicology (AREA)
  • Environmental Sciences (AREA)
  • Organic Chemistry (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Dermatology (AREA)
  • Emergency Medicine (AREA)
  • Medicinal Preparation (AREA)
  • Cosmetics (AREA)

Abstract

La présente invention concerne des produits pour la peau à base d'eau qui sont exempts d'alcool. Ces produits peuvent comprendre un gel ou une mousse pour désinfecter la peau ou un gel lubrifiant transmettant les ultrasons. Le désinfectant pour la peau sous forme de gel ou de mousse peut comprendre un hydratant pour la peau, un agent antimicrobien et un agent d'aide au moussage ou un agent gélifiant. Le gel lubrifiant transmettant les ultrasons peut comprendre un hydratant pour la peau, un agent gélifiant et un lubrifiant.
PCT/GB2008/003485 2007-10-19 2008-10-14 Produits pour la peau à base d'eau Ceased WO2009050447A2 (fr)

Priority Applications (1)

Application Number Priority Date Filing Date Title
ZA2010/03270A ZA201003270B (en) 2007-10-19 2010-05-10 Water-based skin products

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GBGB0720574.3A GB0720574D0 (en) 2007-10-19 2007-10-19 Water-based skin products
GB0720574.3 2007-10-19

Publications (2)

Publication Number Publication Date
WO2009050447A2 true WO2009050447A2 (fr) 2009-04-23
WO2009050447A3 WO2009050447A3 (fr) 2009-08-27

Family

ID=38814202

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/GB2008/003485 Ceased WO2009050447A2 (fr) 2007-10-19 2008-10-14 Produits pour la peau à base d'eau

Country Status (3)

Country Link
GB (2) GB0720574D0 (fr)
WO (1) WO2009050447A2 (fr)
ZA (1) ZA201003270B (fr)

Cited By (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP2320915A4 (fr) * 2008-08-15 2011-10-19 Xttrium Lab Inc Désinfectant doux, non irritant et non alcoolique pour la peau
US8173147B2 (en) 2008-08-15 2012-05-08 Xttrium Laboratories, Inc. Gentle, non-irritating, non-alcoholic skin disinfectant
US9277749B2 (en) 2014-02-07 2016-03-08 Gojo Industries, Inc. Compositions and methods with efficacy against spores and other organisms
US9357771B2 (en) 2012-12-17 2016-06-07 Kimberly-Clark Worldwide, Inc. Foaming sanitizing formulations and products including a quaternary ammonium compound
US9578879B1 (en) 2014-02-07 2017-02-28 Gojo Industries, Inc. Compositions and methods having improved efficacy against spores and other organisms
US9956153B2 (en) 2014-08-01 2018-05-01 Ecolab Usa Inc. Antimicrobial foaming compositions containing cationic active ingredients
CN109260053A (zh) * 2018-11-20 2019-01-25 天津科技大学 一种零皮肤内渗透水基免洗抑菌乳液的制备方法
CN109289059A (zh) * 2018-11-28 2019-02-01 广州润虹医药科技股份有限公司 一种杀菌型医用超声耦合剂及其制备方法
US10308897B2 (en) 2017-04-24 2019-06-04 Gpcp Ip Holdings Llc Alkaline sanitizing soap preparations containing quaternary ammonium chloride agents
CN115040700A (zh) * 2022-03-03 2022-09-13 邯郸市凯琳卫生用品有限公司 一种抗菌性人体润滑剂及其制备方法
US11634666B2 (en) 2015-12-22 2023-04-25 3M Innovative Properties Company Methods for spore removal comprising a polysorbate surfactant and cationic antimicrobial mixture
IT202100031556A1 (it) * 2021-12-16 2023-06-16 Claudio Bandini Gel ecografico
WO2025212766A1 (fr) * 2024-04-03 2025-10-09 Lubrizol Advanced Materials, Inc. Compositions de nettoyage à viscosité élevée

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2009105874A1 (fr) 2008-02-25 2009-09-03 The University Of British Columbia Composition et procédé pour l'irrigation d'un canal radiculaire dentaire préparé
US20120150033A1 (en) * 2010-12-13 2012-06-14 Loren Curtis Rauch Antimicrobial ultrasound transmission gel
CN105999312A (zh) * 2016-06-16 2016-10-12 山东瑞泰奇洗涤消毒科技有限公司 医用消毒超声耦合剂及其制备方法
US20210244663A1 (en) * 2020-02-07 2021-08-12 Mark Edward Fenzl Rapid set gel concentrate for medical products

Citations (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB720574A (en) 1951-09-09 1954-12-22 Philips Electrical Ind Ltd Improvements in or relating to unipolar x-ray tubes
US20030008791A1 (en) 2001-06-06 2003-01-09 Lonza Inc. Non-alcoholic hand sanitizer
US20030139307A1 (en) 2000-10-20 2003-07-24 Narula Vinod K. Sanitizing hand cleanser
US6627207B1 (en) 1998-02-26 2003-09-30 Pro-Ren A/S Water-based, quick-drying, gel-type disinfectant having low alcohol content
US20040219227A1 (en) 2001-10-23 2004-11-04 Shanta Modak Gentle-acting skin-disinfectants and hydroalcoholic gel formulations
US6977082B2 (en) 2001-03-29 2005-12-20 The Dial Corporation High efficacy antibacterial compositions having enhanced esthetic and skin care properties
US20060127316A1 (en) 2004-12-14 2006-06-15 Sonotech, Inc. Polyols and PVP as in vivo biocompatible acoustic coupling media
WO2006092581A1 (fr) 2005-03-01 2006-09-08 Sarah Annabelle Brooks Composition lubrifiante
US7192601B2 (en) 2002-01-18 2007-03-20 Walker Edward B Antimicrobial and sporicidal composition
US20070071537A1 (en) 2005-09-29 2007-03-29 Reddy Kiran K Wiper with encapsulated agent
WO2007038855A1 (fr) 2005-10-04 2007-04-12 Sigmacon Medical Products Corporation Gel medical

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA2510933C (fr) * 1995-06-13 2009-09-08 Zahra Mansouri Procede d'administration de materiaux dans la peau et compositions utilisees lors de ce procede
FR2792532B1 (fr) * 1999-04-26 2001-12-21 Menarini France Lab Nouvelles compositions antiseptiques et leur procede d'obtention
US6927197B1 (en) * 1999-11-08 2005-08-09 Water Journey Ltd. Antibacterial compositions and method of using same
WO2001074983A1 (fr) * 2000-04-04 2001-10-11 Becton, Dickinson And Company Formulation antimicrobienne moussante
US20020123440A1 (en) * 2000-04-04 2002-09-05 Hoang Minh Q. Foamable antimicrobial formulation
US6616922B2 (en) * 2001-03-27 2003-09-09 The Dial Corporation Antibacterial compositions
US20050186281A1 (en) * 2003-09-26 2005-08-25 Mionix Corporation Antimicrobial sanitizing composition
GB0416153D0 (en) * 2004-07-20 2004-08-18 Unilever Plc Laundry product
US7754770B2 (en) * 2005-06-27 2010-07-13 Mason Chemical Company Antimicrobial composition
US20070270321A1 (en) * 2006-05-16 2007-11-22 Barnhart Ronald A Antimicrobial hand wash formulations

Patent Citations (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB720574A (en) 1951-09-09 1954-12-22 Philips Electrical Ind Ltd Improvements in or relating to unipolar x-ray tubes
US6627207B1 (en) 1998-02-26 2003-09-30 Pro-Ren A/S Water-based, quick-drying, gel-type disinfectant having low alcohol content
US20030139307A1 (en) 2000-10-20 2003-07-24 Narula Vinod K. Sanitizing hand cleanser
US6977082B2 (en) 2001-03-29 2005-12-20 The Dial Corporation High efficacy antibacterial compositions having enhanced esthetic and skin care properties
US20030008791A1 (en) 2001-06-06 2003-01-09 Lonza Inc. Non-alcoholic hand sanitizer
US20040219227A1 (en) 2001-10-23 2004-11-04 Shanta Modak Gentle-acting skin-disinfectants and hydroalcoholic gel formulations
US7192601B2 (en) 2002-01-18 2007-03-20 Walker Edward B Antimicrobial and sporicidal composition
US20060127316A1 (en) 2004-12-14 2006-06-15 Sonotech, Inc. Polyols and PVP as in vivo biocompatible acoustic coupling media
WO2006092581A1 (fr) 2005-03-01 2006-09-08 Sarah Annabelle Brooks Composition lubrifiante
US20070071537A1 (en) 2005-09-29 2007-03-29 Reddy Kiran K Wiper with encapsulated agent
WO2007038855A1 (fr) 2005-10-04 2007-04-12 Sigmacon Medical Products Corporation Gel medical

Cited By (25)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2012500195A (ja) * 2008-08-15 2012-01-05 エクストリウム ラボラトーリーズ， インコーポレーテッド 穏やかな、非刺激性、非アルコール性皮膚消毒剤
US8173147B2 (en) 2008-08-15 2012-05-08 Xttrium Laboratories, Inc. Gentle, non-irritating, non-alcoholic skin disinfectant
AU2008360632B2 (en) * 2008-08-15 2013-02-07 Xttrium Laboratories, Inc. Gentle, non-irritating, non-alcohoholic skin disinfectant
EP2320915A4 (fr) * 2008-08-15 2011-10-19 Xttrium Lab Inc Désinfectant doux, non irritant et non alcoolique pour la peau
US9357771B2 (en) 2012-12-17 2016-06-07 Kimberly-Clark Worldwide, Inc. Foaming sanitizing formulations and products including a quaternary ammonium compound
US9578879B1 (en) 2014-02-07 2017-02-28 Gojo Industries, Inc. Compositions and methods having improved efficacy against spores and other organisms
US9820482B2 (en) 2014-02-07 2017-11-21 Gojo Industries, Inc. Compositions and methods with efficacy against spores and other organisms
US9936695B1 (en) 2014-02-07 2018-04-10 Gojo Industries, Inc. Compositions and methods having improved efficacy against spores and other organisms
US10827749B2 (en) 2014-02-07 2020-11-10 Gojo Industries, Inc. Compositions and methods with efficacy against spores and other organisms
US9277749B2 (en) 2014-02-07 2016-03-08 Gojo Industries, Inc. Compositions and methods with efficacy against spores and other organisms
US10334846B2 (en) 2014-02-07 2019-07-02 Gojo Industries, Inc. Compositions and methods with efficacy against spores and other organisms
US10405545B2 (en) 2014-02-07 2019-09-10 Gojo Industries, Inc. Compositions and methods having improved efficacy against spores and other organisms
US10517806B2 (en) 2014-08-01 2019-12-31 Ecolab Usa Inc. Antimicrobial foaming compositions containing cationic active ingredients
US9956153B2 (en) 2014-08-01 2018-05-01 Ecolab Usa Inc. Antimicrobial foaming compositions containing cationic active ingredients
US11634666B2 (en) 2015-12-22 2023-04-25 3M Innovative Properties Company Methods for spore removal comprising a polysorbate surfactant and cationic antimicrobial mixture
US10308897B2 (en) 2017-04-24 2019-06-04 Gpcp Ip Holdings Llc Alkaline sanitizing soap preparations containing quaternary ammonium chloride agents
US10920174B2 (en) 2017-04-24 2021-02-16 Gpcp Ip Holdings Llc Sanitizing soap preparations comprising an amphoteric/cationic surfactant mixture
US11884896B2 (en) 2017-04-24 2024-01-30 Gpcp Ip Holdings Llc Sanitizing soap preparation comprising a benzalkonium chloride/alkyl trimonium cationic surfactant combination
CN109260053B (zh) * 2018-11-20 2021-06-18 天津科技大学 一种零皮肤内渗透水基免洗抑菌乳液的制备方法
CN109260053A (zh) * 2018-11-20 2019-01-25 天津科技大学 一种零皮肤内渗透水基免洗抑菌乳液的制备方法
CN109289059A (zh) * 2018-11-28 2019-02-01 广州润虹医药科技股份有限公司 一种杀菌型医用超声耦合剂及其制备方法
IT202100031556A1 (it) * 2021-12-16 2023-06-16 Claudio Bandini Gel ecografico
WO2023111973A1 (fr) * 2021-12-16 2023-06-22 Bandini Claudio Gel à ultrasons
CN115040700A (zh) * 2022-03-03 2022-09-13 邯郸市凯琳卫生用品有限公司 一种抗菌性人体润滑剂及其制备方法
WO2025212766A1 (fr) * 2024-04-03 2025-10-09 Lubrizol Advanced Materials, Inc. Compositions de nettoyage à viscosité élevée

Also Published As

Publication number Publication date
GB2453858A (en) 2009-04-22
GB0818990D0 (en) 2008-11-26
WO2009050447A3 (fr) 2009-08-27
ZA201003270B (en) 2011-10-26
GB0720574D0 (en) 2007-11-28

Similar Documents

Publication Publication Date Title
WO2009050447A2 (fr) Produits pour la peau à base d'eau
CN101959493B (zh) 手部保湿卫生洗涤剂
CN109381480B (zh) 复配聚六亚甲基双胍消毒液及其制备方法
AU2016329881B2 (en) Personal cleansing compositions and methods of stabilizing the microbiome
JP2015178497A (ja) 潤滑、保湿、消毒や殺菌に使う半流体の組成物及びその使用方法
JP6425660B2 (ja) 改良された抗菌剤組成物
CN112107593B (zh) 一种免洗护手抑菌凝胶及其制备方法
CN102803460A (zh) 抗菌组合物
US20090082472A1 (en) Hand sanitizer and method of preparation
CN103415206B (zh) 低醇抗微生物清洁组合物
JP6830629B2 (ja) 消毒用組成物
JP6866058B2 (ja) 粘稠消毒剤
CN115768395A (zh) 水醇凝胶及所述凝胶的制造方法
JPH10130173A (ja) 速乾性消毒剤
US9775346B1 (en) Hand sanitizer composition and method of manufacture
JP2007031376A (ja) 毛髪・頭皮洗浄剤、経皮吸収促進剤及び経皮吸収促進方法
CN116869899A (zh) 一种护肤除菌免洗凝露及其制备方法
JP2006083111A (ja) 消毒用組成物
CN113952246B (zh) 一种阳离子抑菌免洗手凝胶及其制备方法
JP6869577B2 (ja) 粘稠消毒剤
JP2000086408A (ja) 速乾性手指消毒殺菌剤
JP7045750B1 (ja) 使用感を改善したアルコール系擦り込み式手指消毒組成物
JP6741433B2 (ja) 消毒用乳化組成物
CN103690392B (zh) 含有海洋生物活性物质的婴儿洗发水及组合物、制备方法
WO2023276203A1 (fr) Composition de désinfectant pour les mains à base d'alcool à frictionner offrant une meilleure sensation

Legal Events

Date Code Title Description
121 Ep: the epo has been informed by wipo that ep was designated in this application

Ref document number: 08806605

Country of ref document: EP

Kind code of ref document: A2

NENP Non-entry into the national phase

Ref country code: DE

122 Ep: pct application non-entry in european phase

Ref document number: 08806605

Country of ref document: EP

Kind code of ref document: A2