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WO2008139866A1 - 電気泳動チップおよび電気泳動装置 - Google Patents

電気泳動チップおよび電気泳動装置 Download PDF

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Publication number
WO2008139866A1
WO2008139866A1 PCT/JP2008/057826 JP2008057826W WO2008139866A1 WO 2008139866 A1 WO2008139866 A1 WO 2008139866A1 JP 2008057826 W JP2008057826 W JP 2008057826W WO 2008139866 A1 WO2008139866 A1 WO 2008139866A1
Authority
WO
WIPO (PCT)
Prior art keywords
electrophoresis
vessel
analysis
chip
enables
Prior art date
Application number
PCT/JP2008/057826
Other languages
English (en)
French (fr)
Inventor
Koji Sugiyama
Satoshi Yonehara
Yusuke Nakayama
Original Assignee
Arkray, Inc.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Arkray, Inc. filed Critical Arkray, Inc.
Priority to EP08751964A priority Critical patent/EP2144056A4/en
Priority to JP2009514071A priority patent/JP5064497B2/ja
Priority to CN2008800129265A priority patent/CN101663578B/zh
Priority to US12/514,301 priority patent/US20100032297A1/en
Publication of WO2008139866A1 publication Critical patent/WO2008139866A1/ja
Priority to US13/222,982 priority patent/US20120012462A1/en

Links

Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N27/00—Investigating or analysing materials by the use of electric, electrochemical, or magnetic means
    • G01N27/26—Investigating or analysing materials by the use of electric, electrochemical, or magnetic means by investigating electrochemical variables; by using electrolysis or electrophoresis
    • G01N27/416—Systems
    • G01N27/447—Systems using electrophoresis
    • G01N27/44756—Apparatus specially adapted therefor
    • G01N27/44791—Microapparatus
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L3/00—Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
    • B01L3/50—Containers for the purpose of retaining a material to be analysed, e.g. test tubes
    • B01L3/502—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures
    • B01L3/5027—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures by integrated microfluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip
    • B01L3/50273—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures by integrated microfluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip characterised by the means or forces applied to move the fluids
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K1/00—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
    • C07K1/14—Extraction; Separation; Purification
    • C07K1/24—Extraction; Separation; Purification by electrochemical means
    • C07K1/26—Electrophoresis
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2300/00—Additional constructional details
    • B01L2300/08—Geometry, shape and general structure
    • B01L2300/0861—Configuration of multiple channels and/or chambers in a single devices
    • B01L2300/0867—Multiple inlets and one sample wells, e.g. mixing, dilution
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2300/00—Additional constructional details
    • B01L2300/08—Geometry, shape and general structure
    • B01L2300/0887—Laminated structure
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2300/00—Additional constructional details
    • B01L2300/16—Surface properties and coatings
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2400/00—Moving or stopping fluids
    • B01L2400/04—Moving fluids with specific forces or mechanical means
    • B01L2400/0403—Moving fluids with specific forces or mechanical means specific forces
    • B01L2400/0415—Moving fluids with specific forces or mechanical means specific forces electrical forces, e.g. electrokinetic
    • B01L2400/0421—Moving fluids with specific forces or mechanical means specific forces electrical forces, e.g. electrokinetic electrophoretic flow

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Molecular Biology (AREA)
  • Electrochemistry (AREA)
  • Analytical Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Dispersion Chemistry (AREA)
  • Organic Chemistry (AREA)
  • Biochemistry (AREA)
  • Immunology (AREA)
  • Genetics & Genomics (AREA)
  • Pathology (AREA)
  • Hematology (AREA)
  • Clinical Laboratory Science (AREA)
  • General Chemical & Material Sciences (AREA)
  • Biophysics (AREA)
  • General Physics & Mathematics (AREA)
  • Medicinal Chemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Physics & Mathematics (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Apparatus Associated With Microorganisms And Enzymes (AREA)
  • Automatic Analysis And Handling Materials Therefor (AREA)

Abstract

　小型化および分析時間の短縮が可能で、且つ高精度で糖化ヘモグロビンの分析が可能なキャピラリー電気泳動チップを提供する。 　上基板４と、下基板１と、第１の導入槽２ａと、第１の回収槽２ｂと、試料分析用のキャピラリー流路３ｘとを含み、前記下基板１上に、前記第１の導入槽２ａと前記第１の回収槽２ｂとが形成され、前記第１の導入槽２ａと前記第１の回収槽２ｂとが、前記試料分析用のキャピラリー流路３ｘで連通されている。
PCT/JP2008/057826 2007-04-27 2008-04-23 電気泳動チップおよび電気泳動装置 WO2008139866A1 (ja)

Priority Applications (5)

Application Number Priority Date Filing Date Title
EP08751964A EP2144056A4 (en) 2007-04-27 2008-04-23 ELECTROPHORESIS CHIP AND ELECTROPHORESIS DEVICE
JP2009514071A JP5064497B2 (ja) 2007-04-27 2008-04-23 電気泳動チップおよび電気泳動装置
CN2008800129265A CN101663578B (zh) 2007-04-27 2008-04-23 电泳芯片和电泳装置
US12/514,301 US20100032297A1 (en) 2007-04-27 2008-04-23 Electrophoresis Chip and Electrophoresis Apparatus
US13/222,982 US20120012462A1 (en) 2007-04-27 2011-08-31 Electrophoresis Chip and Electrophoresis Apparatus

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
JP2007-119260 2007-04-27
JP2007119260 2007-04-27

Related Child Applications (1)

Application Number Title Priority Date Filing Date
US13/222,982 Continuation US20120012462A1 (en) 2007-04-27 2011-08-31 Electrophoresis Chip and Electrophoresis Apparatus

Publications (1)

Publication Number Publication Date
WO2008139866A1 true WO2008139866A1 (ja) 2008-11-20

Family

ID=40002082

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/JP2008/057826 WO2008139866A1 (ja) 2007-04-27 2008-04-23 電気泳動チップおよび電気泳動装置

Country Status (5)

Country Link
US (2) US20100032297A1 (ja)
EP (1) EP2144056A4 (ja)
JP (1) JP5064497B2 (ja)
CN (1) CN101663578B (ja)
WO (1) WO2008139866A1 (ja)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN102109490A (zh) * 2009-12-25 2011-06-29 爱科来株式会社 利用电泳法分析血红蛋白的方法

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2008078781A1 (ja) 2006-12-26 2008-07-03 Sekisui Chemical Co., Ltd. ヘモグロビン類の測定方法及び電気泳動装置
JP5616309B2 (ja) 2010-12-01 2014-10-29 アークレイ株式会社 デバイス及びその製造方法
EP3164482B1 (en) * 2014-07-03 2024-05-22 Massachusetts Institute of Technology Apparatus and method for optimization of cell electroporation
US10349589B2 (en) 2016-09-08 2019-07-16 Hemex Health, Inc. Diagnostics systems and methods
AU2017324053B2 (en) 2016-09-08 2020-08-06 Hemex Health, Inc. Diagnostics systems and methods
JP6933551B2 (ja) 2017-10-23 2021-09-08 アークレイ株式会社 判定方法、分析方法及び分析システム
CN108490182B (zh) * 2018-02-06 2021-04-30 深圳市第二人民医院 糖化血红蛋白检测装置及检测方法
WO2020264182A1 (en) 2019-06-25 2020-12-30 Hemex Health, Inc. Diagnostics systems and methods
WO2024086523A2 (en) * 2022-10-20 2024-04-25 Life Technologies Corporation Devices, systems, and methods for processing biological samples using isotachophoresis

Citations (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2000146910A (ja) * 1998-09-02 2000-05-26 Sankyo Co Ltd 電気泳動システム
JP2000310615A (ja) * 1999-02-26 2000-11-07 Hitachi Chem Co Ltd 電気泳動用チップとその製造方法、該電気泳動用チップを用いた電気泳動装置及び荷電性物質の分離方法
WO2002088321A2 (en) * 2001-05-02 2002-11-07 Applera Corporation Concentration and purification of analytes using electric fields
JP2004069430A (ja) * 2002-08-05 2004-03-04 Mitsubishi Kagaku Iatron Inc 電気泳動用チップ、その製造方法、及び物質の分離方法
JP2004151041A (ja) * 2002-11-01 2004-05-27 Asti Corp バイオチップとバイオチップ製造方法
WO2005106448A1 (ja) * 2004-04-28 2005-11-10 Arkray, Inc. 電気泳動チップおよびこれを備えた電気泳動装置
WO2008029684A1 (fr) * 2006-09-04 2008-03-13 National Institute Of Advanced Industrial Science And Technology Procédé pour analyse d'échantillon par électrophorèse capillaire
WO2008029685A1 (fr) * 2006-09-04 2008-03-13 National Institute Of Advanced Industrial Science And Technology Procédé pour analyse d'échantillon par électrophorèse capillaire
JP2008170351A (ja) * 2007-01-12 2008-07-24 Sekisui Chem Co Ltd 電気泳動装置

Family Cites Families (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
BE1004336A3 (fr) * 1991-01-15 1992-11-03 Analis Sa Procede de separation et de quantification de l'hemoglobine glycosylee hb a1c.
US5202006A (en) * 1992-04-17 1993-04-13 Beckman Instruments, Inc. Analysis of hemoglobin variants by capillary zone electrophoresis
US5431793A (en) * 1994-07-29 1995-07-11 Beckman Instruments, Inc. Quantitative analysis of glycosylated hemoglobin by immunocappillary electrophoresis
US5599433A (en) * 1995-01-17 1997-02-04 Beckman Instruments, Inc. Capillary electrophoresis of glycosylated proteins
US5611903A (en) * 1995-03-22 1997-03-18 Analis S. A. Capillary electrophoresis method using initialized capillary and polyanion-containing buffer and chemical kit therefor
US5630924A (en) * 1995-04-20 1997-05-20 Perseptive Biosystems, Inc. Compositions, methods and apparatus for ultrafast electroseparation analysis
JPH11248678A (ja) * 1998-03-06 1999-09-17 Shimadzu Corp キャピラリー電気泳動チップ
US6416642B1 (en) * 1999-01-21 2002-07-09 Caliper Technologies Corp. Method and apparatus for continuous liquid flow in microscale channels using pressure injection, wicking, and electrokinetic injection
TW517154B (en) * 1999-08-11 2003-01-11 Asahi Chemical Ind Analyzing cartridge and liquid feed control device
JP3501090B2 (ja) * 2000-04-10 2004-02-23 株式会社島津製作所 マイクロチップ電気泳動装置
JP4362987B2 (ja) * 2001-04-09 2009-11-11 株式会社島津製作所 マイクロチップ電気泳動におけるサンプル導入方法
FR2825649B1 (fr) * 2001-06-08 2003-10-17 Francois Paul Geli Support pour analyse comparatives d'echantillons sur micro-colonnes de fractionnement avec gradients de longueur, phases stationnaires alternees, et elutions digitalisees
WO2004083823A1 (ja) * 2003-03-19 2004-09-30 Nec Corporation マイクロチップならびに試料抽出方法、試料分離方法、試料分析方法、および試料回収方法
KR20060105787A (ko) * 2003-11-21 2006-10-11 가부시키가이샤 에바라 세이사꾸쇼 액체를 이용한 마이크로칩 장치

Patent Citations (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2000146910A (ja) * 1998-09-02 2000-05-26 Sankyo Co Ltd 電気泳動システム
JP2000310615A (ja) * 1999-02-26 2000-11-07 Hitachi Chem Co Ltd 電気泳動用チップとその製造方法、該電気泳動用チップを用いた電気泳動装置及び荷電性物質の分離方法
WO2002088321A2 (en) * 2001-05-02 2002-11-07 Applera Corporation Concentration and purification of analytes using electric fields
JP2004069430A (ja) * 2002-08-05 2004-03-04 Mitsubishi Kagaku Iatron Inc 電気泳動用チップ、その製造方法、及び物質の分離方法
JP2004151041A (ja) * 2002-11-01 2004-05-27 Asti Corp バイオチップとバイオチップ製造方法
WO2005106448A1 (ja) * 2004-04-28 2005-11-10 Arkray, Inc. 電気泳動チップおよびこれを備えた電気泳動装置
WO2008029684A1 (fr) * 2006-09-04 2008-03-13 National Institute Of Advanced Industrial Science And Technology Procédé pour analyse d'échantillon par électrophorèse capillaire
WO2008029685A1 (fr) * 2006-09-04 2008-03-13 National Institute Of Advanced Industrial Science And Technology Procédé pour analyse d'échantillon par électrophorèse capillaire
JP2008170351A (ja) * 2007-01-12 2008-07-24 Sekisui Chem Co Ltd 電気泳動装置

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
CLINICAL CHEMISTRY, vol. 43, no. 4, 1997, pages 644 - 648

Cited By (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN102109490A (zh) * 2009-12-25 2011-06-29 爱科来株式会社 利用电泳法分析血红蛋白的方法
EP2343544A1 (en) * 2009-12-25 2011-07-13 Arkray, Inc. Method for analyzing hemoglobin by electrophoresis
JP2011149934A (ja) * 2009-12-25 2011-08-04 Arkray Inc 電気泳動法によるヘモグロビンの分析方法
US8702941B2 (en) 2009-12-25 2014-04-22 ARKARY, Inc. Method of analyzing hemoglobin by electrophoresis

Also Published As

Publication number Publication date
CN101663578A (zh) 2010-03-03
US20120012462A1 (en) 2012-01-19
JPWO2008139866A1 (ja) 2010-07-29
US20100032297A1 (en) 2010-02-11
EP2144056A4 (en) 2010-10-27
EP2144056A1 (en) 2010-01-13
CN101663578B (zh) 2013-11-13
JP5064497B2 (ja) 2012-10-31

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