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WO2008136173A1 - Adipocyte differentiation inhibitor containing stilbene derivative as active ingredient - Google Patents

Adipocyte differentiation inhibitor containing stilbene derivative as active ingredient Download PDF

Info

Publication number
WO2008136173A1
WO2008136173A1 PCT/JP2008/000741 JP2008000741W WO2008136173A1 WO 2008136173 A1 WO2008136173 A1 WO 2008136173A1 JP 2008000741 W JP2008000741 W JP 2008000741W WO 2008136173 A1 WO2008136173 A1 WO 2008136173A1
Authority
WO
WIPO (PCT)
Prior art keywords
adipocyte differentiation
obesity
stilbene derivative
differentiation inhibitor
active ingredient
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Ceased
Application number
PCT/JP2008/000741
Other languages
French (fr)
Japanese (ja)
Inventor
Yoko Fujiwara
Kiyoshi Fukuhara
Atsuko Matsuoka
Miki Hasebe
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Ochanomizu University
Original Assignee
Ochanomizu University
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Ochanomizu University filed Critical Ochanomizu University
Priority to JP2009512874A priority Critical patent/JPWO2008136173A1/en
Publication of WO2008136173A1 publication Critical patent/WO2008136173A1/en
Anticipated expiration legal-status Critical
Ceased legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23K—FODDER
    • A23K20/00—Accessory food factors for animal feeding-stuffs
    • A23K20/10—Organic substances
    • A23K20/111—Aromatic compounds
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23L—FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES, NOT OTHERWISE PROVIDED FOR; PREPARATION OR TREATMENT THEREOF
    • A23L33/00—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof
    • A23L33/10—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof using additives
    • A23L33/105—Plant extracts, their artificial duplicates or their derivatives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/045—Hydroxy compounds, e.g. alcohols; Salts thereof, e.g. alcoholates
    • A61K31/05—Phenols
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/04—Anorexiants; Antiobesity agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/06—Antihyperlipidemics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23V—INDEXING SCHEME RELATING TO FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES AND LACTIC OR PROPIONIC ACID BACTERIA USED IN FOODSTUFFS OR FOOD PREPARATION
    • A23V2002/00—Food compositions, function of food ingredients or processes for food or foodstuffs

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Diabetes (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Obesity (AREA)
  • Polymers & Plastics (AREA)
  • Hematology (AREA)
  • Epidemiology (AREA)
  • Food Science & Technology (AREA)
  • Child & Adolescent Psychology (AREA)
  • Zoology (AREA)
  • Animal Husbandry (AREA)
  • Emergency Medicine (AREA)
  • Botany (AREA)
  • Mycology (AREA)
  • Nutrition Science (AREA)
  • Endocrinology (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Coloring Foods And Improving Nutritive Qualities (AREA)

Abstract

It is intended to provide an extremely excellent adipocyte differentiation inhibitor, anti-obesity agent, abnormal glucose tolerance-improving agent, adiponectin production promoter, anti-obesity food, anti-obesity food additive and anti-obesity feed. A stilbene derivative represented by the following general formula (I) is used. (In the formula, R1 to R6 independently represent hydrogen or a hydroxy group, with the proviso that the case where R2, R4 and R6 are a hydroxy group and R1, R3 and R5 are hydrogen is excluded.)
PCT/JP2008/000741 2007-04-20 2008-03-26 Adipocyte differentiation inhibitor containing stilbene derivative as active ingredient Ceased WO2008136173A1 (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
JP2009512874A JPWO2008136173A1 (en) 2007-04-20 2008-03-26 Adipocyte differentiation inhibitor comprising a stilbene derivative as an active ingredient

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
JP2007-112428 2007-04-20
JP2007112428 2007-04-20

Publications (1)

Publication Number Publication Date
WO2008136173A1 true WO2008136173A1 (en) 2008-11-13

Family

ID=39943294

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/JP2008/000741 Ceased WO2008136173A1 (en) 2007-04-20 2008-03-26 Adipocyte differentiation inhibitor containing stilbene derivative as active ingredient

Country Status (2)

Country Link
JP (1) JPWO2008136173A1 (en)
WO (1) WO2008136173A1 (en)

Cited By (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2012511585A (en) * 2008-12-09 2012-05-24 ユニバーシティ オブ フロリダ リサーチ ファウンデーション，インコーポレイテッド Kinase inhibitor compounds
EP2567959A1 (en) 2011-09-12 2013-03-13 Sanofi 6-(4-Hydroxy-phenyl)-3-styryl-1H-pyrazolo[3,4-b]pyridine-4-carboxylic acid amide derivatives as kinase inhibitors
JP2023543229A (en) * 2020-09-25 2023-10-13 シージェイ チェルジェダン コーポレイション Anti-coccidiosis compositions containing stilbene compounds and their uses

Citations (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2001072583A (en) * 1999-09-07 2001-03-21 Sunstar Inc Prophylactic or therapeutic composition for hyperlipemia
JP2003505500A (en) * 1999-07-30 2003-02-12 ザ、プロクター、エンド、ギャンブル、カンパニー Methods and compositions for the prevention and treatment of symptoms associated with colds and flu-like diseases
JP2004537561A (en) * 2001-07-26 2004-12-16 ジョンゴワ・レンミン・ジェファンジュン・ジュンシュ・イーシュエ・ワーシュエ・ユア・ファンシュワ・イーシュエ・イエン・ジュソワ Use of stilbene compounds in the manufacture of a medicament for the prevention and treatment of diabetes or a retrovirus-related disease
FR2862533A1 (en) * 2003-11-21 2005-05-27 Oreal COSMETIC USE OF AT LEAST ONE ACTIVATOR IN THE PRODUCTION OF AN INTERLEUKIN 11 AS A TOPICAL SLIMMING AGENT
BRPI0405370A (en) * 2004-11-29 2006-07-04 Henry Okigami application of trans-resveratrol or other stilbene derivatives in the treatment of localized fat and applied product
WO2007005453A2 (en) * 2005-07-01 2007-01-11 President And Fellows Of Harvard College Compositions for treating or preventing obesity and insulin resistance disorders

Patent Citations (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2003505500A (en) * 1999-07-30 2003-02-12 ザ、プロクター、エンド、ギャンブル、カンパニー Methods and compositions for the prevention and treatment of symptoms associated with colds and flu-like diseases
JP2001072583A (en) * 1999-09-07 2001-03-21 Sunstar Inc Prophylactic or therapeutic composition for hyperlipemia
JP2004537561A (en) * 2001-07-26 2004-12-16 ジョンゴワ・レンミン・ジェファンジュン・ジュンシュ・イーシュエ・ワーシュエ・ユア・ファンシュワ・イーシュエ・イエン・ジュソワ Use of stilbene compounds in the manufacture of a medicament for the prevention and treatment of diabetes or a retrovirus-related disease
FR2862533A1 (en) * 2003-11-21 2005-05-27 Oreal COSMETIC USE OF AT LEAST ONE ACTIVATOR IN THE PRODUCTION OF AN INTERLEUKIN 11 AS A TOPICAL SLIMMING AGENT
BRPI0405370A (en) * 2004-11-29 2006-07-04 Henry Okigami application of trans-resveratrol or other stilbene derivatives in the treatment of localized fat and applied product
WO2007005453A2 (en) * 2005-07-01 2007-01-11 President And Fellows Of Harvard College Compositions for treating or preventing obesity and insulin resistance disorders

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
CHEMICAL ABSTRACTS, vol. 146, no. 10, 5 March 2007, Columbus, Ohio, US; abstract no. 146:189919D, page 1617; *

Cited By (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2012511585A (en) * 2008-12-09 2012-05-24 ユニバーシティ オブ フロリダ リサーチ ファウンデーション，インコーポレイテッド Kinase inhibitor compounds
EP2567959A1 (en) 2011-09-12 2013-03-13 Sanofi 6-(4-Hydroxy-phenyl)-3-styryl-1H-pyrazolo[3,4-b]pyridine-4-carboxylic acid amide derivatives as kinase inhibitors
JP2023543229A (en) * 2020-09-25 2023-10-13 シージェイ チェルジェダン コーポレイション Anti-coccidiosis compositions containing stilbene compounds and their uses
JP7558402B2 (en) 2020-09-25 2024-09-30 シージェイ チェルジェダン コーポレイション Anticoccidiopathic composition containing a stilbene compound and its use

Also Published As

Publication number Publication date
JPWO2008136173A1 (en) 2010-07-29

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