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WO2008133697A1 - Mesure par refléctance de pigment maculaire à l'aide d'une imagerie multispectrale - Google Patents

Mesure par refléctance de pigment maculaire à l'aide d'une imagerie multispectrale Download PDF

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Publication number
WO2008133697A1
WO2008133697A1 PCT/US2007/069167 US2007069167W WO2008133697A1 WO 2008133697 A1 WO2008133697 A1 WO 2008133697A1 US 2007069167 W US2007069167 W US 2007069167W WO 2008133697 A1 WO2008133697 A1 WO 2008133697A1
Authority
WO
WIPO (PCT)
Prior art keywords
filter
grayscale
pass band
color
macular pigment
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Ceased
Application number
PCT/US2007/069167
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English (en)
Inventor
Richard Spaide
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Individual
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Individual
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Filing date
Publication date
Application filed by Individual filed Critical Individual
Publication of WO2008133697A1 publication Critical patent/WO2008133697A1/fr
Anticipated expiration legal-status Critical
Ceased legal-status Critical Current

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Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B3/00—Apparatus for testing the eyes; Instruments for examining the eyes
    • A61B3/10—Objective types, i.e. instruments for examining the eyes independent of the patients' perceptions or reactions
    • A61B3/12—Objective types, i.e. instruments for examining the eyes independent of the patients' perceptions or reactions for looking at the eye fundus, e.g. ophthalmoscopes
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B3/00—Apparatus for testing the eyes; Instruments for examining the eyes
    • A61B3/10—Objective types, i.e. instruments for examining the eyes independent of the patients' perceptions or reactions
    • A61B3/14—Arrangements specially adapted for eye photography
    • A61B3/145—Arrangements specially adapted for eye photography by video means

Definitions

  • the invention also concerns the use of a system comprising, in one embodiment, a fundus camera having a CCD and a Bayer filter, a multiband filter, and a processor processing, storing, and displaying the resultant images, as more fully described in the detailed description.
  • each channel of output from the camera can be viewed in isolation to gain additional information about the ocular fundus. Alterations in the nerve fiber layer of the eye can often be best visualized by using short wavelengths of light as obtained with the blue portion of the filter.
  • the green channel generally supplies the highest spatial resolution because there are more green sensitive elements in the color CCD.
  • the red channel affords better visualization of deeper structures within the retina. Ratiometric comparisons between various channels, or composites of more than one channel can improve visualization as required. For example, an average of the red and green channels may be performed, and the average used to normalize the blue channel by dividing the blue channel with the red/green information, thereby improving contrast.

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Molecular Biology (AREA)
  • Biophysics (AREA)
  • Ophthalmology & Optometry (AREA)
  • Biomedical Technology (AREA)
  • Veterinary Medicine (AREA)
  • Medical Informatics (AREA)
  • Physics & Mathematics (AREA)
  • Surgery (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Multimedia (AREA)
  • Eye Examination Apparatus (AREA)

Abstract

L'invention concerne des procédés et appareils pour imager, évaluer et mesurer de façon précise le pigment maculaire d'un patient. Un filtre multibande est employé en combinaison avec une caméra de fond d'œil numérique en couleur pour fournir un procédé qui fonctionne avec une exposition à simple imagerie. Le filtre multibande a dés régions passe-bande à l'intérieur des plages spectrales des détecteurs du rouge, du vert et du bleu du réseau CCD employé à l'intérieur de la caméra de fond d'œil, les régions passe-bande étant définies de façon suffisamment précise de façon à éviter des régions où les réponses de détecteur CCD sont spectralement chevauchantes. Ceci fournit trois canaux discrets de données de l'échelle de gris correspondant aux régions passe-bande du filtre multibande, qui peuvent être utilisées pour calculer le pigment maculaire de façon topographique. L'invention concerne également des procédés pour calculer la densité optique du pigment maculaire et avantageusement afficher les données résultantes.
PCT/US2007/069167 2007-04-25 2007-05-17 Mesure par refléctance de pigment maculaire à l'aide d'une imagerie multispectrale Ceased WO2008133697A1 (fr)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
US91388507P 2007-04-25 2007-04-25
US60/913,885 2007-04-25
US92635407P 2007-04-26 2007-04-26
US60/926,354 2007-04-26

Publications (1)

Publication Number Publication Date
WO2008133697A1 true WO2008133697A1 (fr) 2008-11-06

Family

ID=39925951

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/US2007/069167 Ceased WO2008133697A1 (fr) 2007-04-25 2007-05-17 Mesure par refléctance de pigment maculaire à l'aide d'une imagerie multispectrale

Country Status (1)

Country Link
WO (1) WO2008133697A1 (fr)

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN106052877A (zh) * 2016-05-25 2016-10-26 敦煌研究院 壁画绘画材料多光谱图像色彩标准色卡及其制作方法
EP3263017A4 (fr) * 2015-02-27 2018-10-24 Kowa Company, Ltd. Système d'imagerie du fond de l'oeil

Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7039452B2 (en) * 2002-12-19 2006-05-02 The University Of Utah Research Foundation Method and apparatus for Raman imaging of macular pigments

Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7039452B2 (en) * 2002-12-19 2006-05-02 The University Of Utah Research Foundation Method and apparatus for Raman imaging of macular pigments

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP3263017A4 (fr) * 2015-02-27 2018-10-24 Kowa Company, Ltd. Système d'imagerie du fond de l'oeil
CN106052877A (zh) * 2016-05-25 2016-10-26 敦煌研究院 壁画绘画材料多光谱图像色彩标准色卡及其制作方法

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