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WO2008131502A3 - Nouveaux composés antiviraux - Google Patents

Nouveaux composés antiviraux Download PDF

Info

Publication number
WO2008131502A3
WO2008131502A3 PCT/BE2008/000033 BE2008000033W WO2008131502A3 WO 2008131502 A3 WO2008131502 A3 WO 2008131502A3 BE 2008000033 W BE2008000033 W BE 2008000033W WO 2008131502 A3 WO2008131502 A3 WO 2008131502A3
Authority
WO
WIPO (PCT)
Prior art keywords
antiviral compounds
compounds
adamantane type
medicine
relates
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Ceased
Application number
PCT/BE2008/000033
Other languages
English (en)
Other versions
WO2008131502A2 (fr
Inventor
Palma Armando De
Antonin Holy
Hubert Hrebabecky
Johan Neyts
Michal Sala
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Katholieke Universiteit Leuven
Czech Academy of Sciences CAS
Institute of Organic Chemistry and Biochemistry CAS
Original Assignee
Katholieke Universiteit Leuven
Czech Academy of Sciences CAS
Institute of Organic Chemistry and Biochemistry CAS
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Katholieke Universiteit Leuven, Czech Academy of Sciences CAS, Institute of Organic Chemistry and Biochemistry CAS filed Critical Katholieke Universiteit Leuven
Publication of WO2008131502A2 publication Critical patent/WO2008131502A2/fr
Publication of WO2008131502A3 publication Critical patent/WO2008131502A3/fr
Anticipated expiration legal-status Critical
Ceased legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D473/00—Heterocyclic compounds containing purine ring systems
    • C07D473/40—Heterocyclic compounds containing purine ring systems with halogen atoms or perhalogeno-alkyl radicals directly attached in position 2 or 6
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Oncology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Virology (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Communicable Diseases (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)

Abstract

La présente invention concerne une série de nouveaux composés qui présentent une activité antivirale, notamment à l'encontre de virus de la famille des picornaviridés (Picornaviridae). Cette invention concerne les nouveaux composés, des procédés de préparation de ceux-ci, des compositions pharmaceutiques les comprenant, ainsi que ces composés utilisés comme médicament, en particulier comme médicament antiviral.
PCT/BE2008/000033 2007-04-27 2008-04-28 Nouveaux composés antiviraux Ceased WO2008131502A2 (fr)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GB0708258.9 2007-04-27
GBGB0708258.9A GB0708258D0 (en) 2007-04-27 2007-04-27 New anti-viral nulceoside analogs

Publications (2)

Publication Number Publication Date
WO2008131502A2 WO2008131502A2 (fr) 2008-11-06
WO2008131502A3 true WO2008131502A3 (fr) 2009-03-05

Family

ID=38170862

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/BE2008/000033 Ceased WO2008131502A2 (fr) 2007-04-27 2008-04-28 Nouveaux composés antiviraux

Country Status (2)

Country Link
GB (1) GB0708258D0 (fr)
WO (1) WO2008131502A2 (fr)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA3005353A1 (fr) 2015-11-20 2017-05-26 Forma Therapeutics, Inc. Purinones utilises comme inhibiteurs de la protease specifique de l'ubiquitine 1

Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0085424A2 (fr) * 1982-02-01 1983-08-10 Syntex (U.S.A.) Inc. 9-(1- ou 3-Monoycyloxy- ou 2,3-diacyloxy-2-propoxyméthyl)purines substituées comme des agents antiviraux
EP0415456A2 (fr) * 1989-09-01 1991-03-06 Kyowa Hakko Kogyo Co., Ltd. Dérivés de xanthine
EP0784974A1 (fr) * 1995-07-26 1997-07-23 Kyowa Hakko Kogyo Co., Ltd. Dispersion solide ou preparation a dispersion solide de derives xanthine
EP0882727A1 (fr) * 1996-07-03 1998-12-09 Japan Energy Corporation Nouveaux derives de purine

Patent Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0085424A2 (fr) * 1982-02-01 1983-08-10 Syntex (U.S.A.) Inc. 9-(1- ou 3-Monoycyloxy- ou 2,3-diacyloxy-2-propoxyméthyl)purines substituées comme des agents antiviraux
EP0415456A2 (fr) * 1989-09-01 1991-03-06 Kyowa Hakko Kogyo Co., Ltd. Dérivés de xanthine
EP0784974A1 (fr) * 1995-07-26 1997-07-23 Kyowa Hakko Kogyo Co., Ltd. Dispersion solide ou preparation a dispersion solide de derives xanthine
EP0882727A1 (fr) * 1996-07-03 1998-12-09 Japan Energy Corporation Nouveaux derives de purine

Non-Patent Citations (3)

* Cited by examiner, † Cited by third party
Title
MARCHAL, A. ET AL.: "Novel Procedure for Selective C-Nitrosation of Aminopyrimidine Derivatives Under Neutral Conditions. Scope and Synthetic Applications", SYNLETT, 2002, pages 255 - 258, XP002496338 *
PETROV, V.I. ET AL.: "9-(2-Aryloxyethyl) Derivatives of Adenine - A new class of Non-Nucleosidix Antiviral Agents", CHEMISTRY OF HETEROCYCLIC COMPOUNDS, vol. 39, no. 9, 2003, pages 1218 - 1226, XP002496337 *
YOUNG R C ET AL: "PURINE DERIVATIVES AS COMPETITIVE INHIBITORS OF HUMAN ERYTHROCYTE MEMBRANE PHOSPHATIDYLINOSITOL 4-KINASE", JOURNAL OF MEDICINAL CHEMISTRY, US AMERICAN CHEMICAL SOCIETY. WASHINGTON, vol. 33, no. 8, 1 August 1990 (1990-08-01), pages 2073 - 2080, XP000573808, ISSN: 0022-2623 *

Also Published As

Publication number Publication date
WO2008131502A2 (fr) 2008-11-06
GB0708258D0 (en) 2007-06-06

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