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WO2008128782A3 - Procédé photochimique d'obtention de prévitamine d - Google Patents

Procédé photochimique d'obtention de prévitamine d Download PDF

Info

Publication number
WO2008128782A3
WO2008128782A3 PCT/EP2008/003320 EP2008003320W WO2008128782A3 WO 2008128782 A3 WO2008128782 A3 WO 2008128782A3 EP 2008003320 W EP2008003320 W EP 2008003320W WO 2008128782 A3 WO2008128782 A3 WO 2008128782A3
Authority
WO
WIPO (PCT)
Prior art keywords
previtamin
preparation
derivative
photochemical process
dehydrosterol
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Ceased
Application number
PCT/EP2008/003320
Other languages
English (en)
Other versions
WO2008128782A2 (fr
Inventor
Rafael Reintjens
Andreas Puhl
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
DSM IP Assets BV
Original Assignee
DSM IP Assets BV
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by DSM IP Assets BV filed Critical DSM IP Assets BV
Publication of WO2008128782A2 publication Critical patent/WO2008128782A2/fr
Publication of WO2008128782A3 publication Critical patent/WO2008128782A3/fr
Anticipated expiration legal-status Critical
Ceased legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C401/00—Irradiation products of cholesterol or its derivatives; Vitamin D derivatives, 9,10-seco cyclopenta[a]phenanthrene or analogues obtained by chemical preparation without irradiation

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Steroid Compounds (AREA)

Abstract

L'invention concerne un procédé photochimique d'obtention de prévitamine D ou d'un dérivé de cette dernière à partir de 7-déhydrostérol ou d'un dérivé correspondant de cette substance. Ce procédé consiste à soumettre le 7-déhydrostérol ou son dérivé à une rayonnement ultraviolet jusqu'à atteindre un taux de transformation maximum du 7-déhydrostérol ou de son dérivé de moins de 12%.
PCT/EP2008/003320 2007-04-24 2008-04-24 Procédé photochimique d'obtention de prévitamine d Ceased WO2008128782A2 (fr)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP07008301.9 2007-04-24
EP07008301 2007-04-24

Publications (2)

Publication Number Publication Date
WO2008128782A2 WO2008128782A2 (fr) 2008-10-30
WO2008128782A3 true WO2008128782A3 (fr) 2008-12-11

Family

ID=39816804

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/EP2008/003320 Ceased WO2008128782A2 (fr) 2007-04-24 2008-04-24 Procédé photochimique d'obtention de prévitamine d

Country Status (2)

Country Link
CN (1) CN101663269A (fr)
WO (1) WO2008128782A2 (fr)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US8263580B2 (en) 1998-09-11 2012-09-11 Stiefel Research Australia Pty Ltd Vitamin formulation
ES2447301T3 (es) 2005-06-01 2014-03-11 Glaxosmithkline Intellectual Property Development Limited Formulación vitamínica
CN110713449A (zh) * 2019-11-12 2020-01-21 广西师范大学 一种维生素d3的高效绿色生产工艺
CN110724081B (zh) * 2019-11-12 2023-08-15 广西师范大学 一种维生素d2的高效生产工艺

Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0028484A1 (fr) * 1979-10-23 1981-05-13 Teijin Limited Procédé de préparation de composés ayant une activité de type vitamine D3 et des cholesta-5,7,diène précurseurs et produits obtenus
EP0967202A1 (fr) * 1998-06-23 1999-12-29 F. Hoffmann-La Roche Ag Photolyse du 7-dehydrocholesterol

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0028484A1 (fr) * 1979-10-23 1981-05-13 Teijin Limited Procédé de préparation de composés ayant une activité de type vitamine D3 et des cholesta-5,7,diène précurseurs et produits obtenus
EP0967202A1 (fr) * 1998-06-23 1999-12-29 F. Hoffmann-La Roche Ag Photolyse du 7-dehydrocholesterol

Non-Patent Citations (2)

* Cited by examiner, † Cited by third party
Title
I. P. TERENETSKAYA ET AL: "Analysis of the two-stage irradiation of provitamin D taking into account the irreversible photoreactions of previtamin", PHARMACEUTICAL CHEMISTRY JOURNAL., vol. 27, no. 11, 1993, USCONSULTANTS BUREAU, NEW YORK, NY, pages 797 - 803, XP002499730 *
M. BRAUN ET AL: "Improved photosynthesis of previtamin D by wavelengths of 280-300 nm", JOURNAL OF PHOTOCHEMISTRY AND PHOTOBIOLOGY, A: CHEMISTRY., vol. 61, no. 1, 1991, CHELSEVIER SEQUOIA, LAUSANNE., pages 15 - 26, XP002499729 *

Also Published As

Publication number Publication date
CN101663269A (zh) 2010-03-03
WO2008128782A2 (fr) 2008-10-30

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