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WO2008127524A3 - Biomarkers of very rapid antidepressant response and of mechanism of very rapid antidepressant response - Google Patents

Biomarkers of very rapid antidepressant response and of mechanism of very rapid antidepressant response Download PDF

Info

Publication number
WO2008127524A3
WO2008127524A3 PCT/US2008/003201 US2008003201W WO2008127524A3 WO 2008127524 A3 WO2008127524 A3 WO 2008127524A3 US 2008003201 W US2008003201 W US 2008003201W WO 2008127524 A3 WO2008127524 A3 WO 2008127524A3
Authority
WO
WIPO (PCT)
Prior art keywords
antidepressant response
rapid antidepressant
biomarkers
rapid
response
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Ceased
Application number
PCT/US2008/003201
Other languages
French (fr)
Other versions
WO2008127524A2 (en
Inventor
Marquis P Vawter
Jr William E Bunney
Joseph Wu
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
University of California
University of California Berkeley
Original Assignee
University of California
University of California Berkeley
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by University of California, University of California Berkeley filed Critical University of California
Publication of WO2008127524A2 publication Critical patent/WO2008127524A2/en
Publication of WO2008127524A3 publication Critical patent/WO2008127524A3/en
Anticipated expiration legal-status Critical
Ceased legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6876—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
    • C12Q1/6883—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00—Oligonucleotides characterized by their use
    • C12Q2600/106—Pharmacogenomics, i.e. genetic variability in individual responses to drugs and drug metabolism
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00—Oligonucleotides characterized by their use
    • C12Q2600/136—Screening for pharmacological compounds
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00—Oligonucleotides characterized by their use
    • C12Q2600/156—Polymorphic or mutational markers
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00—Oligonucleotides characterized by their use
    • C12Q2600/158—Expression markers
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00—Oligonucleotides characterized by their use
    • C12Q2600/172—Haplotypes

Landscapes

  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Wood Science & Technology (AREA)
  • Analytical Chemistry (AREA)
  • Zoology (AREA)
  • Genetics & Genomics (AREA)
  • Engineering & Computer Science (AREA)
  • Pathology (AREA)
  • Immunology (AREA)
  • Microbiology (AREA)
  • Molecular Biology (AREA)
  • Biotechnology (AREA)
  • Biophysics (AREA)
  • Physics & Mathematics (AREA)
  • Biochemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)

Abstract

This invention provides molecular markers that are indicators of subjects that are likely to respond to sleep deprivation as a treatment for a psychiatric disorder. In particular, genes are identified whose expression is altered in responders to sleep deprivation for the treatment of a psychiatric disorder (e.g., depression, mania, etc.).
PCT/US2008/003201 2007-03-07 2008-03-07 Biomarkers of very rapid antidepressant response and of mechanism of very rapid antidepressant response Ceased WO2008127524A2 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US89359007P 2007-03-07 2007-03-07
US60/893,590 2007-03-07

Publications (2)

Publication Number Publication Date
WO2008127524A2 WO2008127524A2 (en) 2008-10-23
WO2008127524A3 true WO2008127524A3 (en) 2009-03-26

Family

ID=39864575

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/US2008/003201 Ceased WO2008127524A2 (en) 2007-03-07 2008-03-07 Biomarkers of very rapid antidepressant response and of mechanism of very rapid antidepressant response

Country Status (1)

Country Link
WO (1) WO2008127524A2 (en)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2016038107A1 (en) * 2014-09-10 2016-03-17 Ceccatelli Sandra Methods and compositions for biomarkers of depression and pharmacoresponse
CN111453831A (en) * 2020-05-11 2020-07-28 浙江养生堂天然药物研究所有限公司 Drinking water for improving sleep quality

Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20050186138A1 (en) * 2003-10-16 2005-08-25 Irm, Llc Methods and compositions for modulating circadian rhythm

Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20050186138A1 (en) * 2003-10-16 2005-08-25 Irm, Llc Methods and compositions for modulating circadian rhythm

Non-Patent Citations (5)

* Cited by examiner, † Cited by third party
Title
BUNNEY ET AL.: "Microarray Technology: A Review of New Strategies to Discover Candidate Vulnerability Genes in Psychiatric Disorders", AM J PSYCHIATRY, vol. 160, 2003, pages 657 - 666 *
BUNNEY ET AL.: "Molecular Clock Genes in Man and Lower Animals: Possible Implications for Circadian Abnormalities in Depression", NEUROPSYCHOPHARMACOLOGY, vol. 22, 2000, pages 335 - 345 *
CONTI ET AL.: "Region-specific transcriptional changes following the three antidepressant treatments electro convulsive therapy, sleep deprivation and fluoxetine", MOLECULAR PSYCHIATRY, vol. 12, February 2007 (2007-02-01), pages 167 - 189 *
D'HAENEN ET AL.: "Biological Psychiatry", vol. II, 2002, JOHN WILEY AND SONS, ISBN: 0471491985 *
VAWTER: "NIH Grant 1R21MH074307-01", NIH GRANT 1R21MH074307-01, 2005, Retrieved from the Internet <URL:http://crisp.cit.nih.gov> [retrieved on 20081218] *

Also Published As

Publication number Publication date
WO2008127524A2 (en) 2008-10-23

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