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WO2008127291A3 - Advanced drug development and manufacturing - Google Patents

Advanced drug development and manufacturing Download PDF

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Publication number
WO2008127291A3
WO2008127291A3 PCT/US2007/021888 US2007021888W WO2008127291A3 WO 2008127291 A3 WO2008127291 A3 WO 2008127291A3 US 2007021888 W US2007021888 W US 2007021888W WO 2008127291 A3 WO2008127291 A3 WO 2008127291A3
Authority
WO
WIPO (PCT)
Prior art keywords
manufacturing
drug development
chemical
advanced drug
xrf
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Ceased
Application number
PCT/US2007/021888
Other languages
French (fr)
Other versions
WO2008127291A2 (en
Inventor
Eva R Birnbaum
Andrew T Koppisch
Sharon M Baldwin
Benjamin P Warner
Mark T Mccleskey
Jennifer A Berger
Jeffrey J Stewart
Michael N Harris
Anthony K Burrell
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Los Alamos National Security LLC
Xrpro Sciences Inc
Original Assignee
Los Alamos National Security LLC
Caldera Pharmaceuticals Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Los Alamos National Security LLC, Caldera Pharmaceuticals Inc filed Critical Los Alamos National Security LLC
Priority to DK07874491.9T priority Critical patent/DK2084519T3/en
Priority to JP2009532446A priority patent/JP5143841B2/en
Priority to EP07874491A priority patent/EP2084519B1/en
Publication of WO2008127291A2 publication Critical patent/WO2008127291A2/en
Anticipated expiration legal-status Critical
Publication of WO2008127291A3 publication Critical patent/WO2008127291A3/en
Ceased legal-status Critical Current

Links

Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/543—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals
    • G01N33/54366—Apparatus specially adapted for solid-phase testing
    • G01N33/54373—Apparatus specially adapted for solid-phase testing involving physiochemical end-point determination, e.g. wave-guides, FETS, gratings
    • G—PHYSICS
    • G21—NUCLEAR PHYSICS; NUCLEAR ENGINEERING
    • G21K—TECHNIQUES FOR HANDLING PARTICLES OR IONISING RADIATION NOT OTHERWISE PROVIDED FOR; IRRADIATION DEVICES; GAMMA RAY OR X-RAY MICROSCOPES
    • G21K7/00—Gamma- or X-ray microscopes
    • G—PHYSICS
    • G21—NUCLEAR PHYSICS; NUCLEAR ENGINEERING
    • G21K—TECHNIQUES FOR HANDLING PARTICLES OR IONISING RADIATION NOT OTHERWISE PROVIDED FOR; IRRADIATION DEVICES; GAMMA RAY OR X-RAY MICROSCOPES
    • G21K2207/00—Particular details of imaging devices or methods using ionizing electromagnetic radiation such as X-rays or gamma rays

Landscapes

  • Health & Medical Sciences (AREA)
  • Immunology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Urology & Nephrology (AREA)
  • Biomedical Technology (AREA)
  • Physics & Mathematics (AREA)
  • Hematology (AREA)
  • Chemical & Material Sciences (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • High Energy & Nuclear Physics (AREA)
  • Food Science & Technology (AREA)
  • Medicinal Chemistry (AREA)
  • Cell Biology (AREA)
  • Analytical Chemistry (AREA)
  • Biotechnology (AREA)
  • General Health & Medical Sciences (AREA)
  • General Physics & Mathematics (AREA)
  • Pathology (AREA)
  • General Engineering & Computer Science (AREA)
  • Microbiology (AREA)
  • Analysing Materials By The Use Of Radiation (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Quinoline Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Measurement Of Radiation (AREA)
  • Other Investigation Or Analysis Of Materials By Electrical Means (AREA)

Abstract

X-ray fluorescence (XRF) spectrometry has been used for detecting binding events and measuring binding selectivities between chemicals and receptors. XRF may also be used for estimating the therapeutic index of a chemical, for estimating the binding selectivity of a chemical versus chemical analogs, for measuring post-translational modifications of proteins, and for drug manufacturing.
PCT/US2007/021888 2006-10-10 2007-10-10 Advanced drug development and manufacturing Ceased WO2008127291A2 (en)

Priority Applications (3)

Application Number Priority Date Filing Date Title
DK07874491.9T DK2084519T3 (en) 2006-10-10 2007-10-10 X-ray fluorescence analysis method
JP2009532446A JP5143841B2 (en) 2006-10-10 2007-10-10 Advanced drug development and manufacturing
EP07874491A EP2084519B1 (en) 2006-10-10 2007-10-10 X-ray fluorescence analysis method

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US85059406P 2006-10-10 2006-10-10
US60/850,594 2006-10-10

Publications (2)

Publication Number Publication Date
WO2008127291A2 WO2008127291A2 (en) 2008-10-23
WO2008127291A3 true WO2008127291A3 (en) 2009-05-14

Family

ID=39864504

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/US2007/021888 Ceased WO2008127291A2 (en) 2006-10-10 2007-10-10 Advanced drug development and manufacturing

Country Status (4)

Country Link
EP (2) EP2084519B1 (en)
JP (3) JP5143841B2 (en)
DK (1) DK2084519T3 (en)
WO (1) WO2008127291A2 (en)

Cited By (4)

* Cited by examiner, † Cited by third party
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US8835382B2 (en) 2009-11-23 2014-09-16 Cubist Pharmaceuticals, Inc. Lipopeptide compositions and related methods
US8946292B2 (en) 2006-03-28 2015-02-03 Javelin Pharmaceuticals, Inc. Formulations of low dose diclofenac and beta-cyclodextrin
CN109380304A (en) * 2018-11-28 2019-02-26 吉林大学 A kind of oxide-based nanomaterial of anti-plant decay disease, preparation method and applications
CN109810991B (en) * 2019-03-02 2021-11-12 昆明理工大学 Application of dihydropteroate synthase gene folP

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US9157875B2 (en) 2001-05-16 2015-10-13 Benjamin P. Warner Drug development and manufacturing
US20080220441A1 (en) 2001-05-16 2008-09-11 Birnbaum Eva R Advanced drug development and manufacturing
US8637528B2 (en) 2007-03-27 2014-01-28 Omeros Corporation Use of PDE7 inhibitors for the treatment of movement disorders
CN101865845A (en) * 2010-06-11 2010-10-20 宁波市疾病预防控制中心 Simple fluorescence analysis method for determining diphacinone and chlorophacinone
CN101897719B (en) * 2010-08-04 2012-01-25 中国人民解放军第三军医大学 Medical composite used for treating smoke inhalation lung injury
JP5926484B2 (en) 2010-11-18 2016-05-25 株式会社セルシード A novel method for the analysis of glycosaminoglycans
JP6596334B2 (en) * 2012-07-10 2019-10-23 ビーエーエスエフ ソシエタス・ヨーロピア Method for producing cobalt sulfate aqueous solution
JP5437525B1 (en) 2012-12-28 2014-03-12 株式会社ナード研究所 Tyrosine derivative and method for producing tyrosine derivative
US20140243220A1 (en) * 2013-02-25 2014-08-28 J. Craig Venter Institute Metaproteomic Method to Identify Secreted Pattern Recognition Molecules and Adhesive Antimicrobial Factors for Detection of Microbial Agents Eliciting Inflammation in the Human Host
KR101651330B1 (en) * 2014-07-28 2016-08-25 가톨릭대학교 산학협력단 Methods of TAT-A20 fusion protein with good cell penetration and use thereof
RU2582960C1 (en) * 2014-10-17 2016-04-27 Федеральное Государственное Бюджетное Образовательное Учреждение Высшего Профессионального Образования "Саратовский Государственный Университет Имени Н.Г. Чернышевского" Method for fluorimetric determination of flunixin
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US10702571B2 (en) 2015-12-03 2020-07-07 The University Of North Carolina At Pembroke Materials for cathepsin B enhancement and methods of use
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US20220136029A1 (en) * 2019-02-08 2022-05-05 Sanofi Biotechnological optimization of microorganisms for the 1,2-dehydrogenation of steroids
CN110075322B (en) * 2019-05-20 2021-07-06 复旦大学附属妇产科医院 A near-infrared fluorescent imaging probe targeting GnRH receptor and its preparation method and application
CN110146621B (en) * 2019-06-13 2022-01-07 国药集团致君（深圳）制药有限公司 Method for determining content of polymer in cephalosporin antibiotic medicine
CA3152258A1 (en) * 2019-09-27 2021-04-01 Sohail F. Tavazoie Compositions and methods for treating metastatic gastrointestinal cancer
CN110628737B (en) * 2019-10-14 2022-06-07 南京农业大学 Related gene for regulating cucumber dwarfing character and application thereof
CN110734899B (en) * 2019-10-31 2021-06-18 江南大学 Sucrose phosphorylase mutant with improved enzyme activity and construction method and application thereof
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US11116737B1 (en) 2020-04-10 2021-09-14 University Of Georgia Research Foundation, Inc. Methods of using probenecid for treatment of coronavirus infections
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JP2023140319A (en) 2022-03-22 2023-10-04 アッヴィ・インコーポレイテッド Pyrimidine for degrading Bruton's tyrosine kinase
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Cited By (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US8946292B2 (en) 2006-03-28 2015-02-03 Javelin Pharmaceuticals, Inc. Formulations of low dose diclofenac and beta-cyclodextrin
US8835382B2 (en) 2009-11-23 2014-09-16 Cubist Pharmaceuticals, Inc. Lipopeptide compositions and related methods
US9138456B2 (en) 2009-11-23 2015-09-22 Cubist Pharmaceuticals Llc Lipopeptide compositions and related methods
CN109380304A (en) * 2018-11-28 2019-02-26 吉林大学 A kind of oxide-based nanomaterial of anti-plant decay disease, preparation method and applications
CN109380304B (en) * 2018-11-28 2020-12-01 吉林大学 A kind of oxide nanomaterial with resistance to plant rot, preparation method and application thereof
CN109810991B (en) * 2019-03-02 2021-11-12 昆明理工大学 Application of dihydropteroate synthase gene folP

Also Published As

Publication number Publication date
JP5913441B2 (en) 2016-04-27
WO2008127291A2 (en) 2008-10-23
JP2010509566A (en) 2010-03-25
EP2084519A4 (en) 2010-02-24
EP2084519A2 (en) 2009-08-05
EP2511844A2 (en) 2012-10-17
JP5143841B2 (en) 2013-02-13
EP2511844B1 (en) 2015-08-12
EP2084519B1 (en) 2012-08-01
EP2511844A3 (en) 2013-03-27
HK1177280A1 (en) 2013-08-16
DK2084519T3 (en) 2012-08-20
JP2014221047A (en) 2014-11-27
JP2012230109A (en) 2012-11-22

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