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WO2008123102A1 - 抗ウイルス剤 - Google Patents

抗ウイルス剤 Download PDF

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Publication number
WO2008123102A1
WO2008123102A1 PCT/JP2008/055087 JP2008055087W WO2008123102A1 WO 2008123102 A1 WO2008123102 A1 WO 2008123102A1 JP 2008055087 W JP2008055087 W JP 2008055087W WO 2008123102 A1 WO2008123102 A1 WO 2008123102A1
Authority
WO
WIPO (PCT)
Prior art keywords
viral agent
viral
disclosed
agent
dimethoxyflavone
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Ceased
Application number
PCT/JP2008/055087
Other languages
English (en)
French (fr)
Inventor
Yuuzou Tsuchida
Kunitomo Watanabe
Mamoru Koketsu
Tsugiya Murayama
Kotarou Tsuchida
Daisuke Sakurai
Mitsuo Kawabe
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Individual
Original Assignee
Individual
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority to TW097109281A priority Critical patent/TWI363621B/zh
Application filed by Individual filed Critical Individual
Priority to JP2009509049A priority patent/JP4384717B2/ja
Priority to US12/532,062 priority patent/US20100121083A1/en
Priority to EP08738680A priority patent/EP2138172A4/en
Publication of WO2008123102A1 publication Critical patent/WO2008123102A1/ja
Anticipated expiration legal-status Critical
Priority to US13/562,068 priority patent/US20120295939A1/en
Priority to US13/744,913 priority patent/US20130131121A1/en
Ceased legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
    • A61K31/35—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having six-membered rings with one oxygen as the only ring hetero atom
    • A61K31/352—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having six-membered rings with one oxygen as the only ring hetero atom condensed with carbocyclic rings, e.g. methantheline 
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/11—Aldehydes
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/4406—Non condensed pyridines; Hydrogenated derivatives thereof only substituted in position 3, e.g. zimeldine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/88—Liliopsida (monocotyledons)
    • A61K36/899—Poaceae or Gramineae (Grass family), e.g. bamboo, corn or sugar cane
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A61P31/14—Antivirals for RNA viruses
    • A61P31/16—Antivirals for RNA viruses for influenza or rhinoviruses
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A61P31/20—Antivirals for DNA viruses
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A61P31/20—Antivirals for DNA viruses
    • A61P31/22—Antivirals for DNA viruses for herpes viruses

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Virology (AREA)
  • Epidemiology (AREA)
  • Natural Medicines & Medicinal Plants (AREA)
  • Engineering & Computer Science (AREA)
  • Biotechnology (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Molecular Biology (AREA)
  • Medical Informatics (AREA)
  • Alternative & Traditional Medicine (AREA)
  • Botany (AREA)
  • Microbiology (AREA)
  • Mycology (AREA)
  • Pulmonology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines Containing Plant Substances (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)

Abstract

　抗ウイルス活性が高く、副作用（細胞毒性）の低い抗ウイルス剤を提供すること。５，７，４’－トリヒドロキシ－3’，５’－ジメトキシフラボン、３－ヒドロキシピリジン、ｐ－ヒドロキシベンズアルデヒド、及びバニリンからなる群から選ばれる少なくとも１種を有効成分とする抗ウイルス剤。
PCT/JP2008/055087 2007-03-19 2008-03-19 抗ウイルス剤 Ceased WO2008123102A1 (ja)

Priority Applications (6)

Application Number Priority Date Filing Date Title
TW097109281A TWI363621B (en) 2007-03-19 2008-03-17 Antiviral composition
JP2009509049A JP4384717B2 (ja) 2007-03-19 2008-03-19 抗ウイルス剤
US12/532,062 US20100121083A1 (en) 2007-03-19 2008-03-19 Anti-viral agent
EP08738680A EP2138172A4 (en) 2007-03-19 2008-03-19 ANTIVIRAL ACTIVE SUBSTANCE
US13/562,068 US20120295939A1 (en) 2007-03-19 2012-07-30 Anti-viral agent
US13/744,913 US20130131121A1 (en) 2007-03-19 2013-01-18 Anti-viral agent

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
JP2007-071409 2007-03-19
JP2007071409 2007-03-19

Related Child Applications (1)

Application Number Title Priority Date Filing Date
US13/562,068 Division US20120295939A1 (en) 2007-03-19 2012-07-30 Anti-viral agent

Publications (1)

Publication Number Publication Date
WO2008123102A1 true WO2008123102A1 (ja) 2008-10-16

Family

ID=39830601

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/JP2008/055087 Ceased WO2008123102A1 (ja) 2007-03-19 2008-03-19 抗ウイルス剤

Country Status (4)

Country Link
US (3) US20100121083A1 (ja)
EP (1) EP2138172A4 (ja)
JP (1) JP4384717B2 (ja)
WO (1) WO2008123102A1 (ja)

Cited By (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2010254649A (ja) * 2009-04-28 2010-11-11 Yuzo Tsuchida 薬剤耐性ウイルスに対する抗ウイルス剤
WO2018194172A1 (ja) 2017-04-21 2018-10-25 土田　裕三 化合物又はその塩、抗ウイルス剤、医薬組成物
JP2022093452A (ja) * 2018-06-25 2022-06-23 ロート製薬株式会社 口腔用組成物

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN102988263B (zh) * 2012-12-20 2014-08-20 中国科学院南海海洋研究所 一种具有护唇、美唇功效的蜂毒组合物
WO2016014699A1 (en) 2014-07-22 2016-01-28 Ralco Nutrition, Inc. Antiviral compositions and methods
WO2017079211A1 (en) * 2015-11-02 2017-05-11 BiOWiSH Technologies, Inc. Compositions and methods of use for reducing evaporative loss from swimming pools and spas
WO2022258125A1 (en) * 2021-06-09 2022-12-15 Elmallah Ahmed Ibrahim Mohamed Elsayed Pharmaceutical compositions of vanillin and wheat germ oil for treatment of covid-19 viral infection and methods of preparation

Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2003201247A (ja) 2001-10-25 2003-07-18 Yuzo Tsuchida 皮膚保護組成物
JP2004359626A (ja) 2003-06-06 2004-12-24 Hoodo:Kk 抗微生物剤
JP2006036731A (ja) 2004-07-30 2006-02-09 Toyo Ink Mfg Co Ltd ササ抽出物、および該抽出物の使用

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS5939411B2 (ja) * 1980-12-24 1984-09-22 野田食菌工業株式会社 抗動物ウイルス剤
EP0565313B1 (en) * 1992-04-02 1997-07-30 Kabushiki Kaisha Hayashibara Seibutsu Kagaku Kenkyujo Method to improve taste preference of pine extract, and orally administrable product obtained thereby
US5411733A (en) * 1992-04-27 1995-05-02 Hozumi; Toyoharu Antiviral agent containing crude drug
NZ532019A (en) * 2001-09-04 2007-04-27 Boehringer Ingelheim Int Anti-influenza drugs
EP1512408A4 (en) * 2002-06-13 2008-01-23 Hououdou Co Ltd ANTIBACTERIAL AGENT AND ANTIBACTERIAL COMPOSITION
BRPI0408814A (pt) * 2003-03-27 2006-04-04 Unigen Inc composição farmacêutica, e, alimento para o cuidado da saúde
JP2005151928A (ja) * 2003-11-28 2005-06-16 Toyo Ink Mfg Co Ltd 飼料用添加剤
JP2005220246A (ja) * 2004-02-06 2005-08-18 Toyo Ink Mfg Co Ltd 粘着剤およびこれを用いたテープもしくはシート
US7351739B2 (en) * 2004-04-30 2008-04-01 Wellgen, Inc. Bioactive compounds and methods of uses thereof

Patent Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2003201247A (ja) 2001-10-25 2003-07-18 Yuzo Tsuchida 皮膚保護組成物
JP2004359626A (ja) 2003-06-06 2004-12-24 Hoodo:Kk 抗微生物剤
JP2006036731A (ja) 2004-07-30 2006-02-09 Toyo Ink Mfg Co Ltd ササ抽出物、および該抽出物の使用

Non-Patent Citations (7)

* Cited by examiner, † Cited by third party
Title
LEE K.H.: "Current Developments in the Discovery and Design of New Drug Candidates from Plant Natural Product Leads", JOURNAL OF NATURAL PRODUCTS, vol. 67, no. 2, 2004, pages 273 - 283, XP008117298 *
LI H. ET AL.: "Evaluation of antiviral activity of compounds isolated from Ranunculus sieboldii and Ranunculus sceleratus", PLANTA MEDICA, vol. 71, no. 12, 2005, pages 1128 - 1133, XP008117297, DOI: doi:10.1055/S-2005-873169 *
M. SHIBATA; K. KUBO; M. ONODA, FOLIA PHARMACOL. JPN, vol. 72, 1976, pages 531 - 541
N. V. CHUYEN; H. KATO, AGRIC. BIOL. CHEM., vol. 46, 1982, pages 2795 - 2801
N. V. CHUYEN; T. KURATA; H. KATO, J ANTIBACT. ANTIFUNG. AGENTS, vol. 11, 1983, pages 69 - 75
See also references of EP2138172A4
TEWTRAKUL S. ET AL.: "Inhibitory effects of flavonoids on human immunodeficiency virus type-1 integrase", WAKAN IYAKUGAKU ZASSHI, vol. 18, no. 6, 2001, pages 229 - 238, XP001247379 *

Cited By (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2010254649A (ja) * 2009-04-28 2010-11-11 Yuzo Tsuchida 薬剤耐性ウイルスに対する抗ウイルス剤
WO2018194172A1 (ja) 2017-04-21 2018-10-25 土田　裕三 化合物又はその塩、抗ウイルス剤、医薬組成物
JP2022093452A (ja) * 2018-06-25 2022-06-23 ロート製薬株式会社 口腔用組成物
JP7463429B2 (ja) 2018-06-25 2024-04-08 ロート製薬株式会社 口腔用組成物

Also Published As

Publication number Publication date
EP2138172A1 (en) 2009-12-30
US20120295939A1 (en) 2012-11-22
EP2138172A8 (en) 2010-02-24
EP2138172A4 (en) 2010-04-28
US20130131121A1 (en) 2013-05-23
JP4384717B2 (ja) 2009-12-16
US20100121083A1 (en) 2010-05-13
JPWO2008123102A1 (ja) 2010-07-15

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