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WO2008116178A3 - Systems and methods for diagnosis and prognosis of colorectal cancer - Google Patents

Systems and methods for diagnosis and prognosis of colorectal cancer Download PDF

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Publication number
WO2008116178A3
WO2008116178A3 PCT/US2008/057884 US2008057884W WO2008116178A3 WO 2008116178 A3 WO2008116178 A3 WO 2008116178A3 US 2008057884 W US2008057884 W US 2008057884W WO 2008116178 A3 WO2008116178 A3 WO 2008116178A3
Authority
WO
WIPO (PCT)
Prior art keywords
colorectal cancer
diagnosis
systems
methods
prognosis
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Ceased
Application number
PCT/US2008/057884
Other languages
French (fr)
Other versions
WO2008116178A8 (en
WO2008116178A2 (en
Inventor
Robert J Coffey
Bruce J Aronow
Jeffrey L Franklin
Timothy Yeatman
Sanne K H Olesen
Gregory Bloom
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Childrens Hospital Research Foundation
H Lee Moffitt Cancer Center and Research Institute Inc
Vanderbilt University
Original Assignee
Childrens Hospital Research Foundation
H Lee Moffitt Cancer Center and Research Institute Inc
Vanderbilt University
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Childrens Hospital Research Foundation, H Lee Moffitt Cancer Center and Research Institute Inc, Vanderbilt University filed Critical Childrens Hospital Research Foundation
Publication of WO2008116178A2 publication Critical patent/WO2008116178A2/en
Publication of WO2008116178A3 publication Critical patent/WO2008116178A3/en
Publication of WO2008116178A8 publication Critical patent/WO2008116178A8/en
Anticipated expiration legal-status Critical
Ceased legal-status Critical Current

Links

Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/574—Immunoassay; Biospecific binding assay; Materials therefor for cancer
    • G01N33/57407—Specifically defined cancers
    • G01N33/57419—Specifically defined cancers of colon
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2800/00—Detection or diagnosis of diseases
    • G01N2800/60—Complex ways of combining multiple protein biomarkers for diagnosis

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Immunology (AREA)
  • Urology & Nephrology (AREA)
  • Chemical & Material Sciences (AREA)
  • Biomedical Technology (AREA)
  • Molecular Biology (AREA)
  • Hematology (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Biotechnology (AREA)
  • Hospice & Palliative Care (AREA)
  • Oncology (AREA)
  • Food Science & Technology (AREA)
  • Microbiology (AREA)
  • Analytical Chemistry (AREA)
  • Cell Biology (AREA)
  • Biochemistry (AREA)
  • Physics & Mathematics (AREA)
  • General Physics & Mathematics (AREA)
  • Pathology (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Other Investigation Or Analysis Of Materials By Electrical Means (AREA)

Abstract

Methods and systems are described for using in making a diagnosis of colorectal cancer in a subject. A method can include providing a biological sample from the subject; determining an amount in the sample of at least one peptide marker, selected from a group of markers as described herein; and comparing the amount of the at least one peptide marker in the sample, if present, to a control level of the at least one peptide marker, wherein the subject is diagnosed as having colorectal cancer or a risk thereof if there is a measurable difference in the amount of the at least one peptide marker in the sample as compared to the control level.
PCT/US2008/057884 2007-03-21 2008-03-21 Systems and methods for diagnosis and prognosis of colorectal cancer Ceased WO2008116178A2 (en)

Applications Claiming Priority (8)

Application Number Priority Date Filing Date Title
US89602007P 2007-03-21 2007-03-21
US60/896,020 2007-03-21
US93830707P 2007-05-16 2007-05-16
US60/938,307 2007-05-16
US96898807P 2007-08-30 2007-08-30
US60/968,988 2007-08-30
US97183907P 2007-09-12 2007-09-12
US60/971,839 2007-09-12

Publications (3)

Publication Number Publication Date
WO2008116178A2 WO2008116178A2 (en) 2008-09-25
WO2008116178A3 true WO2008116178A3 (en) 2008-12-04
WO2008116178A8 WO2008116178A8 (en) 2009-09-17

Family

ID=39766792

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/US2008/057884 Ceased WO2008116178A2 (en) 2007-03-21 2008-03-21 Systems and methods for diagnosis and prognosis of colorectal cancer

Country Status (1)

Country Link
WO (1) WO2008116178A2 (en)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP2239577A1 (en) * 2009-04-07 2010-10-13 Vereniging voor Christelijk Hoger Onderwijs, Wetenschappelijk Onderzoek en Patiëntenzorg Protein-based methods and compositions for the diagnosis of colorectal adenocarcinoma
CN103140760B (en) 2010-07-14 2016-01-27 联邦科学与工业研究组织 Colorectal Cancer Diagnosis
US9141756B1 (en) 2010-07-20 2015-09-22 University Of Southern California Multi-scale complex systems transdisciplinary analysis of response to therapy
CN102586402A (en) * 2011-01-05 2012-07-18 苏州科贝生物技术有限公司 Kit for quantitative evaluation for long-term recurrent risk of colorectal cancer
WO2016164815A1 (en) 2015-04-10 2016-10-13 Applied Proteomics, Inc. Protein biomarker panels for detecting colorectal cancer and advanced adenoma
JP6984862B2 (en) * 2017-03-15 2021-12-22 国立大学法人金沢大学 Detection of colorectal cancer using blood chemokines as markers
TR202019592A2 (en) 2020-12-03 2022-06-21 Sanovel Ilac Sanayi Ve Ticaret Anonim Sirketi Solid pharmaceutical formulations of amorphous dapagliflozin

Non-Patent Citations (2)

* Cited by examiner, † Cited by third party
Title
CHEN ET AL.: "Proteomic analysis of colonic myofibroblasts and effect on colon cancer cell proliferation", SURGERY, vol. 138, no. 2, pages 382 - 390, XP005059700 *
JOYCE ET AL.: "Microarray analysis to reveal genes involved in colon carcinogenesis", EXPERT OPIN. PHARMACOTHER., vol. 8, no. 7, 2007, pages 895 - 900 *

Also Published As

Publication number Publication date
WO2008116178A8 (en) 2009-09-17
WO2008116178A2 (en) 2008-09-25

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