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WO2008111919A3 - A novel combination of water-soluble forms of coenzyme q10 and l-carnitine, process of production and use - Google Patents

A novel combination of water-soluble forms of coenzyme q10 and l-carnitine, process of production and use Download PDF

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Publication number
WO2008111919A3
WO2008111919A3 PCT/SI2008/000012 SI2008000012W WO2008111919A3 WO 2008111919 A3 WO2008111919 A3 WO 2008111919A3 SI 2008000012 W SI2008000012 W SI 2008000012W WO 2008111919 A3 WO2008111919 A3 WO 2008111919A3
Authority
WO
WIPO (PCT)
Prior art keywords
coenzyme
carnitine
water
mixture
novel combination
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Ceased
Application number
PCT/SI2008/000012
Other languages
French (fr)
Other versions
WO2008111919A2 (en
Inventor
Mirko Prosek
Marko Prosek
Alenka Golc-Wondra
Janko Zmitek
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Valens Int d o o
Original Assignee
Valens Int d o o
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Valens Int d o o filed Critical Valens Int d o o
Publication of WO2008111919A2 publication Critical patent/WO2008111919A2/en
Publication of WO2008111919A3 publication Critical patent/WO2008111919A3/en
Anticipated expiration legal-status Critical
Ceased legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0087—Galenical forms not covered by A61K9/02 - A61K9/7023
    • A61K9/0095—Drinks; Beverages; Syrups; Compositions for reconstitution thereof, e.g. powders or tablets to be dispersed in a glass of water; Veterinary drenches
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23L—FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES, NOT OTHERWISE PROVIDED FOR; PREPARATION OR TREATMENT THEREOF
    • A23L2/00—Non-alcoholic beverages; Dry compositions or concentrates therefor; Preparation or treatment thereof
    • A23L2/52—Adding ingredients
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23L—FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES, NOT OTHERWISE PROVIDED FOR; PREPARATION OR TREATMENT THEREOF
    • A23L33/00—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof
    • A23L33/10—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof using additives
    • A23L33/15—Vitamins
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23L—FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES, NOT OTHERWISE PROVIDED FOR; PREPARATION OR TREATMENT THEREOF
    • A23L33/00—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof
    • A23L33/10—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof using additives
    • A23L33/17—Amino acids, peptides or proteins
    • A23L33/175—Amino acids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/12—Ketones
    • A61K31/122—Ketones having the oxygen directly attached to a ring, e.g. quinones, vitamin K1, anthralin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/205—Amine addition salts of organic acids; Inner quaternary ammonium salts, e.g. betaine, carnitine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/33—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing oxygen
    • A61K8/35—Ketones, e.g. benzophenone
    • A61K8/355—Quinones
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/40—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing nitrogen
    • A61K8/44—Aminocarboxylic acids or derivatives thereof, e.g. aminocarboxylic acids containing sulfur; Salts; Esters or N-acylated derivatives thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q19/00—Preparations for care of the skin
    • A61Q19/06—Preparations for care of the skin for countering cellulitis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q19/00—Preparations for care of the skin
    • A61Q19/08—Anti-ageing preparations
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23V—INDEXING SCHEME RELATING TO FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES AND LACTIC OR PROPIONIC ACID BACTERIA USED IN FOODSTUFFS OR FOOD PREPARATION
    • A23V2002/00—Food compositions, function of food ingredients or processes for food or foodstuffs

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Chemical & Material Sciences (AREA)
  • Epidemiology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Medicinal Chemistry (AREA)
  • Polymers & Plastics (AREA)
  • Nutrition Science (AREA)
  • Engineering & Computer Science (AREA)
  • Food Science & Technology (AREA)
  • Mycology (AREA)
  • Birds (AREA)
  • Dermatology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Emergency Medicine (AREA)
  • Gerontology & Geriatric Medicine (AREA)
  • Cosmetics (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)

Abstract

The object of this invention is a novel combination or mixture of water-soluble forms of coenzyme Q10 and L-carnitine, as well as a process of preparing mixtures and products based on this mixture, and the use of mixtures and products based on this mixture. In the novel combination of coenzyme Q10 and L-carnitine according to the invention, the coenzyme Q10, in a suitable form having enhanced water solubility, forms a mixture with L-carnitine. The coenzyme Q10 and L-carnitine are in optional ratios, preferably in a weight ratio within the range of 1 :200 to 10:1, more preferably within the range of 1 :1 to 1 :100. The combination of coenzyme Q10 and L-carnitine is solid or in the form of a solution or suspension in water or an aqueous medium; it can be pure or it comprises added excipients and/or bioactive substances. The combination of coenzyme Q10 and L-carnitine according to the invention is used in the preparation of pharmaceuticals, nutritional products, and cosmetics, as additive, either to the premix or separately.
PCT/SI2008/000012 2007-03-15 2008-02-27 A novel combination of water-soluble forms of coenzyme q10 and l-carnitine, process of production and use Ceased WO2008111919A2 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
SI200700060A SI22465B (en) 2007-03-15 2007-03-15 New combination of water soluble forms of coenzyme q10 and l-carnitin, procedure of preparation and application
SIP-200700060 2007-03-15

Publications (2)

Publication Number Publication Date
WO2008111919A2 WO2008111919A2 (en) 2008-09-18
WO2008111919A3 true WO2008111919A3 (en) 2009-02-05

Family

ID=39760234

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/SI2008/000012 Ceased WO2008111919A2 (en) 2007-03-15 2008-02-27 A novel combination of water-soluble forms of coenzyme q10 and l-carnitine, process of production and use

Country Status (2)

Country Link
SI (1) SI22465B (en)
WO (1) WO2008111919A2 (en)

Citations (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20030129177A1 (en) * 2000-04-04 2003-07-10 Sigma-Tau Healthscience S.P.A. Dietary supplement energy-providing to skeletal muscles and protecting the cardiovascular tract
EP1681053A1 (en) * 2003-10-31 2006-07-19 Kaneka Corporation Composition containing reduced coenzyme q
WO2006110924A2 (en) * 2005-04-14 2006-10-19 Jarrow Formulas, Inc. Dietary supplement formulations for improved delivery of coenzyme q10 and methods of administration
US20060269535A1 (en) * 2005-05-31 2006-11-30 Naidu A S Metallo-lactoferrin-coenzyme compositions for trigger and release of bioenergy
US20060292134A1 (en) * 2005-06-22 2006-12-28 Sidney Stohs Composition for enhancing cellular energy
US20070085059A1 (en) * 2004-02-23 2007-04-19 Texas A&M University System Bioactive Complexes Compositions and Methods of Use Thereof

Patent Citations (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20030129177A1 (en) * 2000-04-04 2003-07-10 Sigma-Tau Healthscience S.P.A. Dietary supplement energy-providing to skeletal muscles and protecting the cardiovascular tract
EP1681053A1 (en) * 2003-10-31 2006-07-19 Kaneka Corporation Composition containing reduced coenzyme q
US20070085059A1 (en) * 2004-02-23 2007-04-19 Texas A&M University System Bioactive Complexes Compositions and Methods of Use Thereof
WO2006110924A2 (en) * 2005-04-14 2006-10-19 Jarrow Formulas, Inc. Dietary supplement formulations for improved delivery of coenzyme q10 and methods of administration
US20060269535A1 (en) * 2005-05-31 2006-11-30 Naidu A S Metallo-lactoferrin-coenzyme compositions for trigger and release of bioenergy
US20060292134A1 (en) * 2005-06-22 2006-12-28 Sidney Stohs Composition for enhancing cellular energy

Also Published As

Publication number Publication date
WO2008111919A2 (en) 2008-09-18
SI22465B (en) 2010-10-29
SI22465A (en) 2008-10-31

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