[go: up one dir, main page]

WO2008109934A3 - Degradation of coumarin based compounds - Google Patents

Degradation of coumarin based compounds Download PDF

Info

Publication number
WO2008109934A3
WO2008109934A3 PCT/AU2008/000319 AU2008000319W WO2008109934A3 WO 2008109934 A3 WO2008109934 A3 WO 2008109934A3 AU 2008000319 W AU2008000319 W AU 2008000319W WO 2008109934 A3 WO2008109934 A3 WO 2008109934A3
Authority
WO
WIPO (PCT)
Prior art keywords
based compounds
degradation
coumarin based
coumarin
aflatoxins
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Ceased
Application number
PCT/AU2008/000319
Other languages
French (fr)
Other versions
WO2008109934A2 (en
Inventor
Matthew C Taylor
David Tattersall
Lyndall J Briggs
Nigel French
Robyn J Russell
John G Oakeshott
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Commonwealth Scientific and Industrial Research Organization CSIRO
Grains Research and Development Corp
Original Assignee
Commonwealth Scientific and Industrial Research Organization CSIRO
Grains Research and Development Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Commonwealth Scientific and Industrial Research Organization CSIRO, Grains Research and Development Corp filed Critical Commonwealth Scientific and Industrial Research Organization CSIRO
Publication of WO2008109934A2 publication Critical patent/WO2008109934A2/en
Publication of WO2008109934A3 publication Critical patent/WO2008109934A3/en
Anticipated expiration legal-status Critical
Ceased legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/0004—Oxidoreductases (1.)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/0004—Oxidoreductases (1.)
    • C12N9/0012—Oxidoreductases (1.) acting on nitrogen containing compounds as donors (1.4, 1.5, 1.6, 1.7)
    • C12N9/0014—Oxidoreductases (1.) acting on nitrogen containing compounds as donors (1.4, 1.5, 1.6, 1.7) acting on the CH-NH2 group of donors (1.4)
    • C12N9/0022—Oxidoreductases (1.) acting on nitrogen containing compounds as donors (1.4, 1.5, 1.6, 1.7) acting on the CH-NH2 group of donors (1.4) with oxygen as acceptor (1.4.3)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Y—ENZYMES
    • C12Y104/00—Oxidoreductases acting on the CH-NH2 group of donors (1.4)
    • C12Y104/03—Oxidoreductases acting on the CH-NH2 group of donors (1.4) with oxygen as acceptor (1.4.3)
    • C12Y104/03005—Pyridoxal 5'-phosphate synthase (1.4.3.5), i.e. pyridoxamine 5-phosphate oxidase

Landscapes

  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Wood Science & Technology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Genetics & Genomics (AREA)
  • Engineering & Computer Science (AREA)
  • Zoology (AREA)
  • General Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Molecular Biology (AREA)
  • Medicinal Chemistry (AREA)
  • Biomedical Technology (AREA)
  • Biotechnology (AREA)
  • Microbiology (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Enzymes And Modification Thereof (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)

Abstract

The present invention relates to the identification of reductase enzymes that degrade coumarin based compounds such as aflatoxins. Methods, including those relying on transgenic organisms, are provided for degrading coumarin based compounds such as aflatoxins.
PCT/AU2008/000319 2007-03-09 2008-03-07 Degradation of coumarin based compounds Ceased WO2008109934A2 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US89395007P 2007-03-09 2007-03-09
US60/893,950 2007-03-09

Publications (2)

Publication Number Publication Date
WO2008109934A2 WO2008109934A2 (en) 2008-09-18
WO2008109934A3 true WO2008109934A3 (en) 2008-12-18

Family

ID=39760128

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/AU2008/000319 Ceased WO2008109934A2 (en) 2007-03-09 2008-03-07 Degradation of coumarin based compounds

Country Status (1)

Country Link
WO (1) WO2008109934A2 (en)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN104611305B (en) * 2014-12-30 2017-11-17 暨南大学 The Aflatoxin-detofizyme that trypsin-resistant improves
CN108514592A (en) * 2018-04-27 2018-09-11 山东省花生研究所 A kind of Chinese medicine preparation of aflatoxin degradation and preparation method thereof
CN112725294B (en) * 2021-01-29 2022-08-30 潍坊康地恩生物科技有限公司 Aflatoxin degrading enzyme mutant and high-yield strain thereof

Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20030013853A1 (en) * 1997-08-08 2003-01-16 Olga Bandman Human aflatoxin B1 aldehyde reductase

Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20030013853A1 (en) * 1997-08-08 2003-01-16 Olga Bandman Human aflatoxin B1 aldehyde reductase

Non-Patent Citations (4)

* Cited by examiner, † Cited by third party
Title
BISWAL B.K. ET AL.: "The molecular structure of Rv2074, a probable pyridoxine 5'-phosphate oxidase from Mycobacterium tuberculosis, at 1.6A resolution", ACTA CRYST., vol. F62, 2006, pages 735 - 742 *
JIN Y. ET AL.: "Aldo-Keto Reductases and Bioactivation/Detoxification", ANNU. REV. PHARMACOL. TOXICOL., vol. 47, 2007, pages 263 - 292 *
MANJUNATHA U.H. ET AL.: "Identification of nitroimidazo-oxazine-specific protein involved in PA-824 resistance in Mycobacterium tuberculosis", PROC. NATL. ACAD. SCI. USA, vol. 103, no. 2, 2006, pages 431 - 436 *
TULAYAKUL P. ET AL.: "Comparative activities of glutathione-S-transferase and dialdehyde reductase toward aflatoxin B1 in livers of experimental and farm animals", TOXICON, vol. 46, 2005, pages 204 - 209, XP004973662 *

Also Published As

Publication number Publication date
WO2008109934A2 (en) 2008-09-18

Similar Documents

Publication Publication Date Title
WO2006092213A8 (en) Pyrazolylcarboxanilides
WO2007085895A3 (en) Fap inhibitors
WO2008097619A3 (en) Variant buttiauxella sp. phytases having altered properties
WO2006065479A3 (en) Substituted phenols as active agents inhibiting vegf production
WO2009047498A3 (en) Mutant enzymes
WO2009100183A3 (en) Variant buttiauxela sp. phytases having altered properties
WO2008005375A3 (en) Kidney toxicity biomarkers
WO2011072099A3 (en) Compositions and methods comprising protease variants
WO2007139871A3 (en) Methods and materials for making simvastatin and related compounds
PT2623113T (en) Compound for enzyme inhibition
WO2008151170A3 (en) Process for the synthesis of ramelteon and its intermediates
AP2330A (en) Mill liner assembly.
WO2007127292A3 (en) Tigeycline crystalline forms and processes for preparation thereof
WO2009014891A3 (en) Increasing plant vigor
WO2006136357A3 (en) Crystalline modifications to pyraclostrobin
WO2010040952A3 (en) Reaction medium for staphylococcus aureus bacteria
WO2008121506A3 (en) Renin inhibitors
WO2006118862A3 (en) Methods for protecting glass
WO2006072612A3 (en) Triazolophthalazines as pde2- inhibitors
WO2008023264A3 (en) Coenzyme q10 production from marine bacteria
WO2009000533A8 (en) Novel herbicides
WO2008051860A3 (en) Anodization
EG25088A (en) Protection of solid acid catalysts from damage by volatile species.
WO2009076948A3 (en) Reductones for producing biogas
WO2008109934A3 (en) Degradation of coumarin based compounds

Legal Events

Date Code Title Description
NENP Non-entry into the national phase

Ref country code: DE

122 Ep: pct application non-entry in european phase

Ref document number: 08714367

Country of ref document: EP

Kind code of ref document: A2