[go: up one dir, main page]

WO2008108385A1 - Method for measurement of glycosylated hexapeptide - Google Patents

Method for measurement of glycosylated hexapeptide Download PDF

Info

Publication number
WO2008108385A1
WO2008108385A1 PCT/JP2008/053907 JP2008053907W WO2008108385A1 WO 2008108385 A1 WO2008108385 A1 WO 2008108385A1 JP 2008053907 W JP2008053907 W JP 2008053907W WO 2008108385 A1 WO2008108385 A1 WO 2008108385A1
Authority
WO
WIPO (PCT)
Prior art keywords
glycosylated
hexapeptide
derived
measurement
protein
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Ceased
Application number
PCT/JP2008/053907
Other languages
French (fr)
Japanese (ja)
Inventor
Kozo Hirokawa
Kazuhiko Shimoji
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Kikkoman Corp
Original Assignee
Kikkoman Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Kikkoman Corp filed Critical Kikkoman Corp
Priority to JP2009502596A priority Critical patent/JP5442432B2/en
Publication of WO2008108385A1 publication Critical patent/WO2008108385A1/en
Anticipated expiration legal-status Critical
Ceased legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/26—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving oxidoreductase
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/72—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving blood pigments, e.g. haemoglobin, bilirubin or other porphyrins; involving occult blood
    • G01N33/721—Haemoglobin
    • G01N33/723—Glycosylated haemoglobin

Landscapes

  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Molecular Biology (AREA)
  • Hematology (AREA)
  • Organic Chemistry (AREA)
  • Immunology (AREA)
  • Physics & Mathematics (AREA)
  • Zoology (AREA)
  • Urology & Nephrology (AREA)
  • Microbiology (AREA)
  • Wood Science & Technology (AREA)
  • Biomedical Technology (AREA)
  • Biotechnology (AREA)
  • Analytical Chemistry (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Pathology (AREA)
  • Biophysics (AREA)
  • General Physics & Mathematics (AREA)
  • Medicinal Chemistry (AREA)
  • Food Science & Technology (AREA)
  • Cell Biology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Engineering & Computer Science (AREA)
  • Genetics & Genomics (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Investigating Or Analysing Biological Materials (AREA)

Abstract

Disclosed is a method for measuring a glycosylated hexapeptide derived from a glycosylated protein rapidly and with high accuracy through a simple manipulation. Also disclosed is a reagent for the measurement. A glycosylated hexapeptide derived from a glycosylated protein in a sample can be measured by reacting the sample containing the glycosylated hexapeptide with a glycosylated hexapeptide oxidase derived from a microorganism for 60 minutes or shorter and measuring a product of the reaction or a material consumed in the reaction. This method enables to measure a glycosylated hexapeptide derived from a glycosylated protein (e.g., glycosylated hemoglobin), which is separated from the glycosylated protein by the action of a protease or the like, simply and with high accuracy.
PCT/JP2008/053907 2007-03-05 2008-03-05 Method for measurement of glycosylated hexapeptide Ceased WO2008108385A1 (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
JP2009502596A JP5442432B2 (en) 2007-03-05 2008-03-05 Method for measuring glycated hexapeptide

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
JP2007-054350 2007-03-05
JP2007054350 2007-03-05

Publications (1)

Publication Number Publication Date
WO2008108385A1 true WO2008108385A1 (en) 2008-09-12

Family

ID=39738258

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/JP2008/053907 Ceased WO2008108385A1 (en) 2007-03-05 2008-03-05 Method for measurement of glycosylated hexapeptide

Country Status (2)

Country Link
JP (1) JP5442432B2 (en)
WO (1) WO2008108385A1 (en)

Cited By (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2011057809A1 (en) 2009-11-16 2011-05-19 Nobel Biocare Services Ag System and method for planning a first and second dental restoration
WO2011126067A1 (en) * 2010-04-09 2011-10-13 東洋紡績株式会社 Method of measuring glycated hemoglobin
EP2639586A1 (en) 2012-03-15 2013-09-18 ARKRAY, Inc. Measurement method using enzymes
WO2013162035A1 (en) 2012-04-27 2013-10-31 キッコーマン株式会社 Modified amadoriase capable of acting on fructosyl hexapeptide
WO2015005257A1 (en) 2013-07-09 2015-01-15 協和メデックス株式会社 Method for measuring glycated hemoglobin
WO2015005258A1 (en) 2013-07-09 2015-01-15 協和メデックス株式会社 Glycated hexapeptide oxidase and use thereof
WO2015060431A1 (en) 2013-10-25 2015-04-30 キッコーマン株式会社 HbA1c MEASUREMENT METHOD USING AMADORIASE ACTING ON GLYCATED PEPTIDES
WO2015060429A1 (en) 2013-10-25 2015-04-30 キッコーマン株式会社 HEMOGLOBIN A1c MEASUREMENT METHOD AND MEASUREMENT KIT
WO2018101389A1 (en) 2016-11-30 2018-06-07 東洋紡株式会社 Method for measuring glycation rate of hemoglobin
WO2019045052A1 (en) 2017-08-31 2019-03-07 キッコーマン株式会社 Glycated hemoglobin oxidase variant and measurement method
US10934530B2 (en) 2015-04-03 2021-03-02 Kikkoman Corporation Amadoriase having improved specific activity
US11111517B2 (en) 2016-04-22 2021-09-07 Kikkoman Corporation HbA1c dehydrogenase
US11168349B2 (en) 2016-07-29 2021-11-09 Hitachi Chemical Diagnostics Systems Co., Ltd. Method for measuring glycated hemoglobin
US11384381B2 (en) 2016-07-13 2022-07-12 Kikkoman Corporation Reaction accelerating agent

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP3949854B2 (en) * 1999-10-01 2007-07-25 キッコーマン株式会社 Method for measuring glycated protein
JP4231668B2 (en) * 2001-09-04 2009-03-04 キッコーマン株式会社 Novel fructosyl peptide oxidase
JP4227820B2 (en) * 2003-03-12 2009-02-18 旭化成ファーマ株式会社 New enzyme
JP2005110657A (en) * 2003-09-18 2005-04-28 Kikkoman Corp METHOD FOR PRODUCING alpha-SACCHARIFIED DIPEPTIDE AND METHOD FOR MEASURING alpha-SACCHARIFIED DIPEPTIDE

Non-Patent Citations (4)

* Cited by examiner, † Cited by third party
Title
AKAZAWA, S. ET AL.: "Functional analysis of fructosyl-amino acid oxidases of Aspergillus oryzae.", APPLIED AND ENVIRONMENTAL MICROBIOLOGY, vol. 70, no. 10, 2004, pages 5882 - 5890, XP055352052 *
HIROKAWA, K. ET AL.: "An enzymatic method for the determination of hemoglobinAlC.", BIOTECHNOLOGY LETTERS, vol. 27, 2005, pages 963 - 968, XP019230894 *
HIROKAWA, K. ET AL.: "Enzymes used for the determination of HbA1C.", FEMS MICROBIOLOGY LETTERS, vol. 235, 2004, pages 157 - 162, XP003014720 *
HIROKAWA, K. ET AL.: "Molecular cloning and expression of novel fructosyl peptide oxidases and their application for the measurement of glycated protein.", BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS, vol. 311, no. 1, 2003, pages 104 - 111, XP004465110 *

Cited By (32)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2011057809A1 (en) 2009-11-16 2011-05-19 Nobel Biocare Services Ag System and method for planning a first and second dental restoration
WO2011126067A1 (en) * 2010-04-09 2011-10-13 東洋紡績株式会社 Method of measuring glycated hemoglobin
EP2639586A1 (en) 2012-03-15 2013-09-18 ARKRAY, Inc. Measurement method using enzymes
US8802366B2 (en) 2012-03-15 2014-08-12 Arkray, Inc. Measurement method using enzyme
WO2013162035A1 (en) 2012-04-27 2013-10-31 キッコーマン株式会社 Modified amadoriase capable of acting on fructosyl hexapeptide
US10767211B2 (en) 2012-04-27 2020-09-08 Kikkoman Corporation Modified amadoriase reacting with fructosyl hexapeptide
EP3508577A2 (en) 2012-04-27 2019-07-10 Kikkoman Corporation Modified amadoriase capable of acting on fructosyl hexapeptide
US9944970B2 (en) 2013-07-09 2018-04-17 Kyowa Medex Co., Ltd. Glycated hexapeptide oxidase and use thereof
WO2015005257A1 (en) 2013-07-09 2015-01-15 協和メデックス株式会社 Method for measuring glycated hemoglobin
WO2015005258A1 (en) 2013-07-09 2015-01-15 協和メデックス株式会社 Glycated hexapeptide oxidase and use thereof
US10006923B2 (en) 2013-07-09 2018-06-26 Kyowa Medex Co., Ltd. Method for measuring glycated hemoglobin
US11078517B2 (en) 2013-10-25 2021-08-03 Kikkoman Corporation Hemoglobin A1c measurement method and measurement kit
CN105683390B (en) * 2013-10-25 2021-02-26 龟甲万株式会社 HbA1c measurement method using amadoriase acting on glycosylated peptide
US20160274129A1 (en) * 2013-10-25 2016-09-22 Kikkoman Corporation METHOD FOR MEASUREMENT OF HbA1c USING AMADORIASE THAT REACTS WITH GLYCATED PEPTIDE
KR102390400B1 (en) * 2013-10-25 2022-04-25 기꼬만 가부시키가이샤 HbA1c measurement method using amadoriase acting on glycated peptides
CN105683390A (en) * 2013-10-25 2016-06-15 龟甲万株式会社 HbA1c measurement method using amadoriase acting on glycated peptides
JP7043161B2 (en) 2013-10-25 2022-03-29 キッコーマン株式会社 HbA1c measurement method using amadriase acting on glycated peptide
KR20160068966A (en) * 2013-10-25 2016-06-15 기꼬만 가부시키가이샤 HbA1c measurement method using amadoriase acting on glycated peptides
US10697979B2 (en) 2013-10-25 2020-06-30 Kikkoman Corporation Method for measurement of HbA1c using amadoriase that reacts with glycated peptide
WO2015060431A1 (en) 2013-10-25 2015-04-30 キッコーマン株式会社 HbA1c MEASUREMENT METHOD USING AMADORIASE ACTING ON GLYCATED PEPTIDES
WO2015060429A1 (en) 2013-10-25 2015-04-30 キッコーマン株式会社 HEMOGLOBIN A1c MEASUREMENT METHOD AND MEASUREMENT KIT
JP2020141690A (en) * 2013-10-25 2020-09-10 キッコーマン株式会社 HbA1c measurement method using amadriase acting on glycated peptides
JPWO2015060431A1 (en) * 2013-10-25 2017-03-09 キッコーマン株式会社 Method for measuring HbA1c using amadoriase acting on glycated peptide
US10934530B2 (en) 2015-04-03 2021-03-02 Kikkoman Corporation Amadoriase having improved specific activity
US11111517B2 (en) 2016-04-22 2021-09-07 Kikkoman Corporation HbA1c dehydrogenase
JP2022081510A (en) * 2016-04-22 2022-05-31 キッコーマン株式会社 HbA1c dehydrogenase
US11384381B2 (en) 2016-07-13 2022-07-12 Kikkoman Corporation Reaction accelerating agent
US11168349B2 (en) 2016-07-29 2021-11-09 Hitachi Chemical Diagnostics Systems Co., Ltd. Method for measuring glycated hemoglobin
EP3550030A4 (en) * 2016-11-30 2020-08-12 Toyobo Co., Ltd. METHOD OF MEASURING THE RATE OF GLYCATION OF HEMOGLOBIN
WO2018101389A1 (en) 2016-11-30 2018-06-07 東洋紡株式会社 Method for measuring glycation rate of hemoglobin
WO2019045052A1 (en) 2017-08-31 2019-03-07 キッコーマン株式会社 Glycated hemoglobin oxidase variant and measurement method
US12258589B2 (en) 2017-08-31 2025-03-25 Kikkoman Corporation Glycated hemoglobin oxidase variant and method for measurement

Also Published As

Publication number Publication date
JPWO2008108385A1 (en) 2010-06-17
JP5442432B2 (en) 2014-03-12

Similar Documents

Publication Publication Date Title
WO2008108385A1 (en) Method for measurement of glycosylated hexapeptide
WO2008070865A3 (en) Materials and methods for efficient and accurate detection of analytes
TW200606420A (en) Biosensors having improved sample application and uses thereof
WO2008078781A1 (en) Hemoglobin measurement method and electrophoresis apparatus
WO2003057850A3 (en) Binding proteins as biosensors
WO2008014132A3 (en) Combination analyte measurement device and method of use
WO2011012848A8 (en) Improvements relating to sensor devices
CN104105968A (en) Hemolysis reagent composition for hemoglobin a1c quantitative analysis using enzymatic method
WO2003046148A3 (en) Polypeptide quantitation
Liu et al. A portable fluorescence biosensor for rapid and sensitive glutathione detection by using quantum dots-based lateral flow test strip
SG10201408392PA (en) Methods of determining patient response by measurement of her-3
TW200720441A (en) New labelling strategies for the sensitive detection of analytes
AU2002350779A1 (en) Analyzer and analysing method and a fluid cartridge
DE602007012455D1 (en) METHOD FOR QUANTITATING CHOLESTERIN IN SMALL-SEALED LOW-DENSITY-LIPOPROTEIN
ATE532063T1 (en) ELECTROCHEMICAL BIOSENSOR
TWI265677B (en) Coding module, bio measuring meter and system for operating bio measuring meter
WO2004057336A3 (en) Use of nicotinamide n-methyltransferase as a marker for colorectal cancer
DE602006011756D1 (en) COMPLEX FORMING AND SEPARATION METHOD
WO2009006877A3 (en) Determination of the activity of proteases
WO2005010485A3 (en) Methods for detecting and analyzing n-glycolylneuraminic acid (neu5gc) in biological materials
WO2009021908A3 (en) Disposable enzymatic sensor for liquid samples
WO2005124356A3 (en) Use of protein cbp2 as a marker for colorectal cancer
PL1952154T3 (en) Turbidimetric immunoassay for assessing human cystatin c
WO2009132100A3 (en) Method for creating a standard for multiple analytes found in a starting material of biological origin
EP1693463A4 (en) PROCESS FOR MEASURING THE QUANTITY OF SACCHARIFIED AMINE

Legal Events

Date Code Title Description
121 Ep: the epo has been informed by wipo that ep was designated in this application

Ref document number: 08721327

Country of ref document: EP

Kind code of ref document: A1

WWE Wipo information: entry into national phase

Ref document number: 2009502596

Country of ref document: JP

NENP Non-entry into the national phase

Ref country code: DE

122 Ep: pct application non-entry in european phase

Ref document number: 08721327

Country of ref document: EP

Kind code of ref document: A1