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WO2008102572A1 - Ｌ－アミノ酸または核酸の製造方法 - Google Patents

Ｌ－アミノ酸または核酸の製造方法 Download PDF

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Publication number
WO2008102572A1
WO2008102572A1 PCT/JP2008/050135 JP2008050135W WO2008102572A1 WO 2008102572 A1 WO2008102572 A1 WO 2008102572A1 JP 2008050135 W JP2008050135 W JP 2008050135W WO 2008102572 A1 WO2008102572 A1 WO 2008102572A1
Authority
WO
WIPO (PCT)
Prior art keywords
amino acid
nucleic acid
crystal
culture medium
production
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Ceased
Application number
PCT/JP2008/050135
Other languages
English (en)
French (fr)
Inventor
Masayuki Araki
Yusuke Takahashi
Akihiro Watanabe
Fumito Ohnishi
Takahiro Asano
Kazuya Kondo
Wataru Hibino
Shintaro Iwatani
Satoshi Okutani
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Ajinomoto Co Inc
Original Assignee
Ajinomoto Co Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Ajinomoto Co Inc filed Critical Ajinomoto Co Inc
Priority to KR1020097019277A priority Critical patent/KR101452202B1/ko
Priority to CN2008800056160A priority patent/CN101617054B/zh
Priority to BRPI0807598A priority patent/BRPI0807598B1/pt
Priority to EP08703006.0A priority patent/EP2130924B1/en
Publication of WO2008102572A1 publication Critical patent/WO2008102572A1/ja
Priority to US12/541,204 priority patent/US8178322B2/en
Anticipated expiration legal-status Critical
Ceased legal-status Critical Current

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    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P13/00—Preparation of nitrogen-containing organic compounds
    • C12P13/04—Alpha- or beta- amino acids
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P19/00—Preparation of compounds containing saccharide radicals
    • C12P19/26—Preparation of nitrogen-containing carbohydrates
    • C12P19/28—N-glycosides
    • C12P19/38—Nucleosides
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P13/00—Preparation of nitrogen-containing organic compounds
    • C12P13/04—Alpha- or beta- amino acids
    • C12P13/08—Lysine; Diaminopimelic acid; Threonine; Valine
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P13/00—Preparation of nitrogen-containing organic compounds
    • C12P13/04—Alpha- or beta- amino acids
    • C12P13/14—Glutamic acid; Glutamine
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P13/00—Preparation of nitrogen-containing organic compounds
    • C12P13/04—Alpha- or beta- amino acids
    • C12P13/22—Tryptophan; Tyrosine; Phenylalanine; 3,4-Dihydroxyphenylalanine
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P19/00—Preparation of compounds containing saccharide radicals
    • C12P19/26—Preparation of nitrogen-containing carbohydrates
    • C12P19/28—N-glycosides
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P19/00—Preparation of compounds containing saccharide radicals
    • C12P19/26—Preparation of nitrogen-containing carbohydrates
    • C12P19/28—N-glycosides
    • C12P19/30—Nucleotides
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P19/00—Preparation of compounds containing saccharide radicals
    • C12P19/26—Preparation of nitrogen-containing carbohydrates
    • C12P19/28—N-glycosides
    • C12P19/30—Nucleotides
    • C12P19/32—Nucleotides having a condensed ring system containing a six-membered ring having two N-atoms in the same ring, e.g. purine nucleotides, nicotineamide-adenine dinucleotide
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P19/00—Preparation of compounds containing saccharide radicals
    • C12P19/26—Preparation of nitrogen-containing carbohydrates
    • C12P19/28—N-glycosides
    • C12P19/38—Nucleosides
    • C12P19/40—Nucleosides having a condensed ring system containing a six-membered ring having two nitrogen atoms in the same ring, e.g. purine nucleosides

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  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Zoology (AREA)
  • Engineering & Computer Science (AREA)
  • Wood Science & Technology (AREA)
  • Health & Medical Sciences (AREA)
  • Microbiology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Biotechnology (AREA)
  • Biochemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)

Abstract

　Ｌ－アミノ酸又は核酸の生産能を有する微生物を攪拌翼を備えた発酵槽中の液体培地で培養し、必要に応じて種晶を培地に添加して当該培地中にＬ－アミノ酸または核酸の結晶を生成、蓄積させ、培養物からＬ－アミノ酸又は核酸の結晶を採取するＬ－アミノ酸又は核酸の製造法において、攪拌翼の動力密度を結晶析出後又は種晶添加後に2.4kW/m3以下に制御する。
PCT/JP2008/050135 2007-02-20 2008-01-09 Ｌ－アミノ酸または核酸の製造方法 Ceased WO2008102572A1 (ja)

Priority Applications (5)

Application Number Priority Date Filing Date Title
KR1020097019277A KR101452202B1 (ko) 2007-02-20 2008-01-09 Ｌ-아미노산 또는 핵산의 제조방법
CN2008800056160A CN101617054B (zh) 2007-02-20 2008-01-09 L-氨基酸或核酸的生产方法
BRPI0807598A BRPI0807598B1 (pt) 2007-02-20 2008-01-09 método para produzir um l-aminoácido ou em ácido nucléico
EP08703006.0A EP2130924B1 (en) 2007-02-20 2008-01-09 Method for production of l-amino acid or nucleic acid
US12/541,204 US8178322B2 (en) 2007-02-20 2009-08-14 Method for producing an L-amino acid or a nucleic acid

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
JP2007-039843 2007-02-20
JP2007039843A JP2010110216A (ja) 2007-02-20 2007-02-20 Ｌ−アミノ酸または核酸の製造方法

Related Child Applications (1)

Application Number Title Priority Date Filing Date
US12/541,204 Continuation US8178322B2 (en) 2007-02-20 2009-08-14 Method for producing an L-amino acid or a nucleic acid

Publications (1)

Publication Number Publication Date
WO2008102572A1 true WO2008102572A1 (ja) 2008-08-28

Family

ID=39709852

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/JP2008/050135 Ceased WO2008102572A1 (ja) 2007-02-20 2008-01-09 Ｌ－アミノ酸または核酸の製造方法

Country Status (8)

Country Link
US (1) US8178322B2 (ja)
EP (1) EP2130924B1 (ja)
JP (1) JP2010110216A (ja)
KR (1) KR101452202B1 (ja)
CN (2) CN103382492B (ja)
BR (1) BRPI0807598B1 (ja)
HU (1) HUE026366T2 (ja)
WO (1) WO2008102572A1 (ja)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2015091265A (ja) * 2008-10-29 2015-05-14 株式会社カネカ Ｌ−アミノ酸の製造方法

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* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP2471940A1 (en) * 2010-12-31 2012-07-04 Süd-Chemie AG Efficient lignocellulose hydrolysis with integrated enzyme production
BR112013023465B1 (pt) * 2011-04-01 2020-10-27 Ajinomoto Co., Inc método para produzir l-cisteína
CN103833813B (zh) * 2014-02-25 2016-03-16 天津普恒康泰科技有限公司 一种基于等电溶析耦合制备腺苷酸晶体的方法
KR102797879B1 (ko) * 2015-11-20 2025-04-22 코베스트로 도이칠란트 아게 아미노벤조산 또는 아미노벤조산 유도체의 제조 방법
CN110117568B (zh) * 2018-02-06 2021-03-30 中国科学院微生物研究所 生产l-组氨酸的重组菌、其构建方法以及l-组氨酸的生产方法
CN111411134B (zh) * 2019-09-18 2023-05-12 大连民族大学 一种海洋芽孢杆菌Bacillus sp.JIN118发酵生产嘌呤的制备方法
CN110863022A (zh) * 2019-09-30 2020-03-06 大连民族大学 嘌呤的发酵生产工艺
CN112522338A (zh) * 2020-12-28 2021-03-19 江苏澳创生物科技有限公司 一种提高l-色氨酸发酵产率的方法
KR102495918B1 (ko) * 2021-01-26 2023-02-06 씨제이제일제당 주식회사 aroG 알돌라아제 (Phospho-2-dehydro-3-deoxyheptonate aldolase) 변이체 및 이를 이용한 분지쇄 아미노산 생산 방법
KR102281365B1 (ko) * 2021-01-26 2021-07-22 씨제이제일제당 (주) 신규한 프롤린 탈수소효소 변이체 및 이를 이용한 l-발린 생산 방법
KR102279137B1 (ko) * 2021-04-29 2021-07-19 씨제이제일제당 주식회사 신규한 아데닌 포스포리보실기 전이효소 변이체 및 이를 이용한 imp 생산 방법
KR102277409B1 (ko) * 2021-04-29 2021-07-14 씨제이제일제당 주식회사 신규한 2중기능성 포스포리보실아미노이미다졸카르복사미드 포밀트랜스퍼라아제/imp 사이클로하이드롤라아제 변이체 및 이를 이용한 imp 생산 방법
CA3247995A1 (en) * 2022-01-11 2025-07-10 Daesang Corporation METHOD FOR PREPARING A SEASONING SUBSTANCE BY MIXED FERMENTATION UNDER THE EFFECT OF HETEROGENEOUS MICROBES

Citations (133)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR356739A (fr) 1904-09-20 1905-12-07 Charles Glauser Perrin Mécanisme de remontoir et de mise à l'heure
JPS384395B1 (ja) 1959-01-14 1963-04-24
US3575809A (en) 1965-01-18 1971-04-20 Ajinomoto Kk Method of producing guanosine by fermentation
US3616206A (en) 1965-09-04 1971-10-26 Takeda Chemical Industries Ltd Method for the production of inosine
JPS50113209A (ja) 1974-02-13 1975-09-05
JPS5137347A (ja) 1974-09-26 1976-03-29 Seiichi Kitabayashi
JPS5238088A (en) 1975-09-19 1977-03-24 Ajinomoto Co Inc Preparation of l-glutamic acid
JPS5325034A (en) 1976-08-19 1978-03-08 Fujii Denko Anti precipitation device for horizontal movement
JPS5417033A (en) 1977-07-07 1979-02-08 Canon Inc Fixing roller for zerography
JPS5436233A (en) 1977-08-22 1979-03-16 Sumitomo Chem Co Ltd Obtainment of optically active isomers of threo-3-(3, 4-benzyloxy-phenyl)-n- carbobenzyloxy-cerin
JPS5545199A (en) 1978-09-22 1980-03-29 Rockwell International Corp Self bias structure for magnetic bubble domain
JPS561889A (en) 1979-06-20 1981-01-10 Ajinomoto Co Inc Preparation of l-glutamic acid by fermentation
JPS5612438A (en) 1979-07-13 1981-02-06 Mitsubishi Heavy Ind Ltd Drag suction-head for sludge dredging
JPS5635981A (en) 1979-08-31 1981-04-08 Ajinomoto Co Inc Novel variant
JPS5648890A (en) 1979-08-10 1981-05-02 Ajinomoto Co Inc Preparation of l-glutamic acid by fermentation
JPS56140895A (en) 1980-04-02 1981-11-04 Ajinomoto Co Inc Preparation of l-glutamic acid by fermentation
JPS56151495A (en) 1980-04-25 1981-11-24 Ajinomoto Co Inc Production of l-glutamine through fermentation
JPS572689A (en) 1981-03-23 1982-01-08 Ajinomoto Co Inc Preparation of l-glutamic acid
JPS5714160A (en) 1980-06-27 1982-01-25 Matsushita Electric Industrial Co Ltd Airconditioner
JPS5741915A (en) 1980-08-27 1982-03-09 Makoto Mori Manufacture of knife handle having sealed object inside thereof
JPS5765198A (en) 1980-10-09 1982-04-20 Ajinomoto Co Inc Fermentative production of l-glutamic acid
JPS5771397A (en) 1980-08-22 1982-05-04 Ajinomoto Co Inc Preparation of l-tryptophan by fermentation method
JPS58158192A (ja) 1982-03-15 1983-09-20 Ajinomoto Co Inc 発酵法によるｌ−グルタミン酸の製造方法
US4407952A (en) 1979-06-15 1983-10-04 Ajinomoto Company Incorporated Method for producing L-phenylalanine by fermentation
JPS5942895A (ja) 1982-07-27 1984-03-09 Takeda Chem Ind Ltd イノシンおよびグアノシンの製造法
EP0149911A2 (en) 1984-01-09 1985-07-31 Minnesota Mining And Manufacturing Company Electrical connector locator plate
JPS6115695A (ja) 1984-06-29 1986-01-23 Ajinomoto Co Inc 発酵法によるｌ−イソロイシンの製造方法
JPS6115696A (ja) 1984-06-29 1986-01-23 Ajinomoto Co Inc 発酵法によるｌ−イソロイシンの製造法
JPS61202694A (ja) 1985-03-07 1986-09-08 Ajinomoto Co Inc 発酵法によるｌ−グルタミンの製造法
JPS62288A (ja) 1985-03-09 1987-01-06 Sanraku Inc 発酵法によるｌ−アミノ酸の製造方法
JPS6214794A (ja) 1985-07-09 1987-01-23 Ajinomoto Co Inc 発酵法によるグアノシン及び／またはイノシンの製造法
JPS6230735A (ja) * 1985-08-02 1987-02-09 Meiji Seika Kaisha Ltd 新抗生物質ｓｆ−２４１８物質及びその製造法
JPS6234397A (ja) 1985-08-08 1987-02-14 Mitsubishi Electric Corp ダイナミツクメモリ装置
JPS6274293A (ja) 1985-09-28 1987-04-06 Kyowa Hakko Kogyo Co Ltd Ｌ−イソロイシンの製造法
JPS6291193A (ja) 1985-06-05 1987-04-25 Kyowa Hakko Kogyo Co Ltd Ｌ−スレオニンおよびｌ−イソロイシンの製造法
JPS62181281A (ja) * 1985-09-13 1987-08-08 ゲゼルシヤフト　ヒユア　ビオテクノロギツシエフオルシユング　ミツト　ベシユレンクテル　ハフツング 大環式抗生物質及びその製造方法
JPS62195293A (ja) 1986-02-22 1987-08-28 Kyowa Hakko Kogyo Co Ltd 発酵法によるｌ−イソロイシンの製造法
JPS62244382A (ja) 1986-04-16 1987-10-24 Ajinomoto Co Inc 新規プロモーター及び該プロモーターを用いた遺伝子発現方法
JPS63214189A (ja) 1987-03-04 1988-09-06 Asahi Chem Ind Co Ltd Ｌ―グルタミン酸の製造方法
JPS63230094A (ja) 1987-03-18 1988-09-26 Kyowa Hakko Kogyo Co Ltd ５′−イノシン酸の製造法
JPS63240794A (ja) 1987-03-30 1988-10-06 Ajinomoto Co Inc Ｌ−トリプトフアンの製造法
JPS63248392A (ja) 1987-04-06 1988-10-14 Kyowa Hakko Kogyo Co Ltd 発酵法によるｌ−ロイシンの製造法
EP0331145A2 (en) 1988-03-04 1989-09-06 Kyowa Hakko Kogyo Co., Ltd. Process for producing amino acids
KR890003681B1 (ko) 1987-03-26 1989-09-30 주식회사 미원 미생물에 의한 l-페닐 알라닌의 제조방법
WO1990004636A1 (fr) 1988-10-25 1990-05-03 Vsesojuzny Nauchno-Issledovatelsky Institut Genetiki I Selektsii Promyshlennykh Mikroorganizmov (Vniigenetika) Souche de bacteries escherichia coli, productrices de la threonine l
JPH02186994A (ja) 1989-01-13 1990-07-23 Ajinomoto Co Inc 発酵法によるｌ‐アミノ酸の製造法
JPH02303495A (ja) 1989-05-17 1990-12-17 Kyowa Hakko Kogyo Co Ltd 芳香族アミノ酸の製造法
JPH036929B2 (ja) 1982-06-15 1991-01-31 Toyo Tire & Rubber Co
JPH0358787A (ja) 1989-04-19 1991-03-13 Takeda Chem Ind Ltd Ｄｎａおよびその用途
WO1991008286A1 (fr) 1989-12-05 1991-06-13 Kyowa Hakko Kogyo Co., Ltd. Inosine guanosine kinase
JPH03216195A (ja) * 1990-01-22 1991-09-24 Ajinomoto Co Inc アミノ酸・核酸およびその誘導体の精製方法
JPH03232497A (ja) 1990-02-08 1991-10-16 Asahi Chem Ind Co Ltd 発酵法によるｌ―グルタミンの製造方法
JPH0428357A (ja) 1990-05-24 1992-01-30 Topcon Corp レーザ装置
JPH0488994A (ja) 1990-07-30 1992-03-23 Kyowa Hakko Kogyo Co Ltd 発酵法によるｌ―グルタミン酸の製造法
EP0488424A2 (en) 1990-11-30 1992-06-03 Ajinomoto Co., Inc. Recombinant DNA sequences encoding feedback inhibition released enzymes, plasmids comprising the recombinant DNA sequences, transformed microorganisms useful in the production of aromatic amino acids, and a process for preparing aromatic amino acids by fermentation
FR2669935A1 (fr) 1990-11-30 1992-06-05 Ajinomoto Kk Procede et appareil pour la regulation de la concentration de source de carbone dans la culture aerobie d'un micro-organisme.
JPH04262790A (ja) 1991-02-19 1992-09-18 Kyowa Hakko Kogyo Co Ltd 発酵法による５’−キサンチル酸の製造法
JPH0549489A (ja) 1991-08-22 1993-03-02 Ajinomoto Co Inc 発酵法によるｌ−フエニルアラニンの製造法
JPH0592944A (ja) 1991-07-16 1993-04-16 Ajinomoto Co Inc アミノ酸・核酸またはその誘導体の製造方法
JPH05130882A (ja) 1991-11-11 1993-05-28 Kyowa Hakko Kogyo Co Ltd 発酵法によるｌ−イソロイシンの製造法
JPH05304971A (ja) * 1992-01-30 1993-11-19 Ajinomoto Co Inc Ｌ−フェニルアラニンの製造法
JPH05304969A (ja) 1992-02-25 1993-11-19 Kyowa Hakko Kogyo Co Ltd 発酵法によるアミノ酸の製造法
JPH0665314A (ja) 1992-01-31 1994-03-08 Spherilene Srl オレフィンの重合用の成分及び触媒
WO1994008031A1 (de) 1992-09-28 1994-04-14 Consortium für elektrochemische Industrie GmbH Mikroorganismen für die produktion von tryptophan und verfahren zu ihrer herstellung
EP0593792A1 (en) 1992-10-14 1994-04-27 Ajinomoto Co., Inc. Novel L-threonine-producing microbacteria and a method for the production of L-threonine
US5354672A (en) 1992-11-24 1994-10-11 Ian Fotheringham Materials and methods for hypersecretion of amino acids
WO1995006114A1 (en) 1993-08-24 1995-03-02 Ajinomoto Co., Inc. Variant phosphoenolpyruvate carboxylase, gene thereof, and process for producing amino acid
JPH07231793A (ja) 1993-12-27 1995-09-05 Ajinomoto Co Inc ヌクレオシド−５’−燐酸エステルの製造法
WO1995034672A1 (en) 1994-06-14 1995-12-21 Ajinomoto Co., Inc. α-KETOGLUTARIC DEHYDROGENASE GENE
WO1996006926A1 (fr) 1994-08-30 1996-03-07 Ajinomoto Co., Inc. Procede pour produire de la l-valine et de la l-leucine
JPH0870879A (ja) 1994-06-30 1996-03-19 Kyowa Hakko Kogyo Co Ltd 発酵法によるｌ−ロイシンの製造法
JPH08168383A (ja) 1995-09-11 1996-07-02 Kyowa Hakko Kogyo Co Ltd 核酸関連物質の製造法
EP0733712A1 (en) 1993-10-28 1996-09-25 Ajinomoto Co., Inc. Process for producing substance
WO1996030501A1 (en) 1995-03-24 1996-10-03 Ajinomoto Co., Inc. Process for producing nucleic acids
JPH08266295A (ja) 1995-03-30 1996-10-15 Ajinomoto Co Inc Ｌ−ロイシンの製造方法
WO1996037603A1 (fr) 1995-05-25 1996-11-28 Ajinomoto Co., Inc. Procede de production du nucleoside-5'-phosphate
WO1997008333A1 (fr) 1995-08-30 1997-03-06 Ajinomoto Co., Inc. Procede de production d'acides amines levogyres
EP0763127A1 (en) 1994-06-09 1997-03-19 Purdue Research Foundation Deblocking the common pathway of aromatic amino acid synthesis
US5658766A (en) 1991-05-30 1997-08-19 Ajinomoto Co., Inc. Strains of Escherichia coli which produce isoleucine or valine and a method for their production
JPH10500002A (ja) * 1994-02-10 1998-01-06 バイオテクニカル リソーシス エル．ピー． 微生物におけるｌ−アスコルビン酸の生成
WO1998004715A1 (en) 1996-07-30 1998-02-05 Archer-Daniels-Midland Company Novel strains of escherichia coli, methods of preparing the same and use thereof in fermentation processes for l-threonine production
US5756345A (en) 1995-09-05 1998-05-26 Degussa Aktiengesellschaft Production of tryptophan by the bacterium Escherichia coli
US5763230A (en) 1996-03-22 1998-06-09 Triple-A B.V. P/A Produkschap Voor Veevoedor Amino acid fermentation processes
JPH10201481A (ja) 1996-11-21 1998-08-04 Ajinomoto Co Inc ヌクレオシド−５’−燐酸エステルの製造法
WO1999018228A2 (de) 1997-10-04 1999-04-15 Forschungszentrum Jülich GmbH Verfahren zur mikrobiellen herstellung von aminosäuren der aspartat- und/oder glutamatfamilie und im verfahren einsetzbare mittel
JPH11155571A (ja) 1997-11-25 1999-06-15 Ajinomoto Co Inc Ｌ−システインの製造法
US5932453A (en) 1996-10-15 1999-08-03 Ajinomoto Co., Ltd. Process for producing L-amino acid through fermentation
US5972663A (en) 1997-06-19 1999-10-26 Consortium Fur Elektrochemische Industrie Gmbh Microorganisms and processes for the fermentative preparation of L-cysteine, L-cystine, N-acetylserine or thiazolidine derivatives
EP0952221A2 (en) 1998-03-18 1999-10-27 Ajinomoto Co., Ltd. L-Glutamic acid-producing bacterium and method for producing L-glutamic acid
EP0955368A2 (en) 1998-03-18 1999-11-10 Ajinomoto Co., Ltd. L-glutamic acid-producing bacterium and method for producing l-glutamic acid
US5998178A (en) 1994-05-30 1999-12-07 Ajinomoto Co., Ltd. L-isoleucine-producing bacterium and method for preparing L-isoleucine through fermentation
EP0994190A2 (en) 1998-10-13 2000-04-19 Ajinomoto Co., Inc. DNA conferring L-homoserine resistance to bacteria, and its use
EP1013765A1 (en) 1998-12-23 2000-06-28 Ajinomoto Co., Ltd. Gene and method for producing L-amino acids
EP1016710A2 (en) 1998-12-30 2000-07-05 Ajinomoto Co., Inc. Method for producing L-amino acids
US6124121A (en) 1997-10-29 2000-09-26 Ajinomoto Co., Inc. Method for producing L-leucine
JP2000295996A (ja) 1999-02-08 2000-10-24 Kyowa Hakko Kogyo Co Ltd プリンヌクレオチドの製造法
WO2001002545A1 (fr) 1999-07-02 2001-01-11 Ajinomoto Co., Inc. Procede de production d'acide l-amine
WO2001002542A1 (fr) 1999-07-02 2001-01-11 Ajinomoto Co., Inc. Procede de production d'acide l-amine
EP1070376A1 (de) 1998-04-09 2001-01-24 Siemens Aktiengesellschaft Anordnung und verfahren zur elektrischen energieversorgung einer elektrischen last
EP1078989A2 (en) 1999-08-20 2001-02-28 Ajinomoto Co., Ltd. Method for producing L-glutamic acid by fermentation accompanied by precipitation
US6218168B1 (en) 1995-10-26 2001-04-17 CONSORTIUM FüR ELEKTROCHEMISCHE INUDSTRIE GMBH Process for preparing O-acetylserine, L-cysteine and L-cysteine-related products
EP1092776A1 (en) 1999-10-14 2001-04-18 Ajinomoto Co., Inc. Method for producing L-amino acid by fermentation
WO2001027307A1 (de) 1999-10-14 2001-04-19 Consortium für elektrochemische Industrie GmbH Verfahren zur fermentativen herstellung von l-cystein oder l-cystein-derivaten
JP2001169788A (ja) 1999-10-27 2001-06-26 Degussa Huels Ag 分枝アミノ酸の排出をコードするヌクレオチド配列、その単離法および使用
US6284495B1 (en) 1998-06-12 2001-09-04 Ajinomoto Co., Inc. Method for producing nucleic acid substances
JP2001245676A (ja) 1995-05-25 2001-09-11 Ajinomoto Co Inc 変異型酸性フォスファターゼ
JP3225597B2 (ja) 1992-06-15 2001-11-05 味の素株式会社 発酵法によるｌ−フェニルアラニンの製造法
JP2001346578A (ja) 2000-04-26 2001-12-18 Ajinomoto Co Inc アミノ酸生産菌及びアミノ酸の製造法
JP2002000289A (ja) 2000-06-23 2002-01-08 Ajinomoto Co Inc ヌクレオシド−５’−燐酸エステルの製造法
WO2002026993A1 (en) 2000-09-28 2002-04-04 Archer-Daniels-Midland Company Escherichia coli strains which over-produce l-threonine and processes for the production of l-threonine by fermentation
US6403342B1 (en) 1999-07-09 2002-06-11 Anjinomoto Co., Inc. DNA coding for mutant isopropylmalate synthase L-leucine-producing microorganism and method for producing L-leucine
EP1233068A2 (en) 2001-02-20 2002-08-21 Ajinomoto Co., Inc. Method for producing L-glutamic acid
EP1239041A2 (en) 2001-02-13 2002-09-11 Ajinomoto Co., Inc. Method for producing L-amino acid using bacteria belonging to the genus Escherichia
JP2002300887A (ja) 2001-02-05 2002-10-15 Ajinomoto Co Inc 発酵法によるｌ−グルタミンの製造法及びｌ−グルタミン生産菌
WO2003004598A2 (en) 2001-07-06 2003-01-16 Degussa Ag Process for the preparation of l-amino acids using strains of the enterobacteriaceae family
WO2003008611A2 (en) 2001-07-18 2003-01-30 Degussa Ag Process for the preparation of l-amino acids using strains of the enterobacteriaceae family which contain an enhanced talb gene
WO2003048374A1 (en) 2001-12-05 2003-06-12 Dsm Ip Assets B.V. Process for the production of an aromatic amino acid metabolite or derivative thereof
KR20030056490A (ko) 2001-12-28 2003-07-04 씨제이 주식회사 5'-크산틸산을 생산하는 미생물
JP2003219876A (ja) 2002-01-24 2003-08-05 Ajinomoto Co Inc プリンヌクレオシドおよびプリンヌクレオチドの製造方法
US20030148473A1 (en) 2001-11-23 2003-08-07 Ajinomoto Co., Inc. Method for producing L-amino acid using bacteria belonging to the genus escherichia
US20030157667A1 (en) 2001-11-23 2003-08-21 Ajinomoto Co., Inc. Method for producing L-amino acids using bacteria belonging to the genus escherichia
JP2004187684A (ja) 2002-11-26 2004-07-08 Ajinomoto Co Inc Ｌ−グルタミンの製造法及びｌ−グルタミン生産菌
US20040166575A1 (en) 2003-02-17 2004-08-26 Misa Tominaga Inosine producing bacterium belonging to the genus Bacillus and method for producing inosine
WO2004090125A2 (en) 2003-04-07 2004-10-21 Ajinomoto Co., Inc. Method for producing l-amino acid using bacteria having enhanced expression of the gene pcka
EP1484410A1 (en) 2003-06-05 2004-12-08 Ajinomoto Co., Ltd. Fermentation methods and genetically modified bacteria with increased substrate and byproduct uptake.
RU2003121601A (ru) 2003-07-16 2005-02-27 Закрытое акционерное общество "Научно-исследовательский институт "Аджиномото-Генетика" (ЗАО "АГРИ") (RU) Мутантная серинацетилтрансфераза
WO2005049808A1 (en) 2003-11-21 2005-06-02 Ajinomoto Co., Inc. Method for producing l-amino acid by fermentation
US6905819B1 (en) 1999-08-12 2005-06-14 Ajinomoto Co., Inc. Plasmid autonomously replicable in coryneform bacteria
WO2005103275A1 (ja) 2004-04-26 2005-11-03 Ajinomoto Co., Ltd. 発酵法によるｌ－トリプトファンの製造法
EP1616940A1 (en) 2004-06-15 2006-01-18 Ajinomoto Co., Inc. L-tyrosine-producing bacterium and a method for producing L-tyrosine
WO2006070944A2 (en) 2004-12-28 2006-07-06 Ajinomoto Co., Inc. L-glutamic acid-producing microorganism and a method for producing l-glutamic acid
JP3823099B2 (ja) 2003-06-26 2006-09-20 中日産業株式会社 キャリーカート
WO2006109830A1 (ja) 2005-04-12 2006-10-19 Kyowa Hakko Kogyo Co., Ltd. アミノ酸の製造法

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
BE620900A (ja) * 1961-08-01
US5001059A (en) * 1985-07-01 1991-03-19 Bio-Technical Resources, Inc. L-ascorbic acid production in microorganisms
FR2686898B1 (fr) * 1992-01-30 1996-09-20 Ajinomoto Kk Methode de production de la l-phenylalanine.
AU3674500A (en) * 1999-04-09 2000-11-14 Ajinomoto Co., Inc. L-amino acid-producing bacteria and process for producing l-amino acid
JP2002209596A (ja) * 2001-01-19 2002-07-30 Ajinomoto Co Inc Ｌ−アミノ酸の製造法
CN1429812A (zh) * 2002-01-03 2003-07-16 刘世斋 一种谷氨酸提取方法
AU2004248005A1 (en) * 2003-06-10 2004-12-23 Ajinomoto Co., Inc. Process for producing L-glutamic acid
WO2005010794A2 (en) * 2003-07-29 2005-02-03 Ajinomoto Co., Inc. Method for determining metabolic flux affecting substance production
JP2009153382A (ja) * 2006-03-30 2009-07-16 Ajinomoto Co Inc メタノール資化性細菌を用いたカルボン酸の製造法

Patent Citations (145)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR356739A (fr) 1904-09-20 1905-12-07 Charles Glauser Perrin Mécanisme de remontoir et de mise à l'heure
JPS384395B1 (ja) 1959-01-14 1963-04-24
US3575809A (en) 1965-01-18 1971-04-20 Ajinomoto Kk Method of producing guanosine by fermentation
US3616206A (en) 1965-09-04 1971-10-26 Takeda Chemical Industries Ltd Method for the production of inosine
JPS50113209A (ja) 1974-02-13 1975-09-05
JPS5137347A (ja) 1974-09-26 1976-03-29 Seiichi Kitabayashi
JPS5238088A (en) 1975-09-19 1977-03-24 Ajinomoto Co Inc Preparation of l-glutamic acid
JPS5325034A (en) 1976-08-19 1978-03-08 Fujii Denko Anti precipitation device for horizontal movement
JPS5417033A (en) 1977-07-07 1979-02-08 Canon Inc Fixing roller for zerography
JPS5436233A (en) 1977-08-22 1979-03-16 Sumitomo Chem Co Ltd Obtainment of optically active isomers of threo-3-(3, 4-benzyloxy-phenyl)-n- carbobenzyloxy-cerin
JPS5545199A (en) 1978-09-22 1980-03-29 Rockwell International Corp Self bias structure for magnetic bubble domain
US4407952A (en) 1979-06-15 1983-10-04 Ajinomoto Company Incorporated Method for producing L-phenylalanine by fermentation
JPS561889A (en) 1979-06-20 1981-01-10 Ajinomoto Co Inc Preparation of l-glutamic acid by fermentation
JPS5612438A (en) 1979-07-13 1981-02-06 Mitsubishi Heavy Ind Ltd Drag suction-head for sludge dredging
JPS5648890A (en) 1979-08-10 1981-05-02 Ajinomoto Co Inc Preparation of l-glutamic acid by fermentation
JPS5635981A (en) 1979-08-31 1981-04-08 Ajinomoto Co Inc Novel variant
JPS56140895A (en) 1980-04-02 1981-11-04 Ajinomoto Co Inc Preparation of l-glutamic acid by fermentation
JPS56151495A (en) 1980-04-25 1981-11-24 Ajinomoto Co Inc Production of l-glutamine through fermentation
JPS5714160A (en) 1980-06-27 1982-01-25 Matsushita Electric Industrial Co Ltd Airconditioner
US4371614A (en) 1980-08-22 1983-02-01 Ajinomoto Co., Inc. E.Coli bacteria carrying recombinant plasmids and their use in the fermentative production of L-tryptophan
JPS5771397A (en) 1980-08-22 1982-05-04 Ajinomoto Co Inc Preparation of l-tryptophan by fermentation method
JPS5741915A (en) 1980-08-27 1982-03-09 Makoto Mori Manufacture of knife handle having sealed object inside thereof
JPS5765198A (en) 1980-10-09 1982-04-20 Ajinomoto Co Inc Fermentative production of l-glutamic acid
JPS572689A (en) 1981-03-23 1982-01-08 Ajinomoto Co Inc Preparation of l-glutamic acid
JPS58158192A (ja) 1982-03-15 1983-09-20 Ajinomoto Co Inc 発酵法によるｌ−グルタミン酸の製造方法
JPH036929B2 (ja) 1982-06-15 1991-01-31 Toyo Tire & Rubber Co
JPS5942895A (ja) 1982-07-27 1984-03-09 Takeda Chem Ind Ltd イノシンおよびグアノシンの製造法
EP0149911A2 (en) 1984-01-09 1985-07-31 Minnesota Mining And Manufacturing Company Electrical connector locator plate
JPS6115695A (ja) 1984-06-29 1986-01-23 Ajinomoto Co Inc 発酵法によるｌ−イソロイシンの製造方法
JPS6115696A (ja) 1984-06-29 1986-01-23 Ajinomoto Co Inc 発酵法によるｌ−イソロイシンの製造法
JPS61202694A (ja) 1985-03-07 1986-09-08 Ajinomoto Co Inc 発酵法によるｌ−グルタミンの製造法
JPS62288A (ja) 1985-03-09 1987-01-06 Sanraku Inc 発酵法によるｌ−アミノ酸の製造方法
JPS6291193A (ja) 1985-06-05 1987-04-25 Kyowa Hakko Kogyo Co Ltd Ｌ−スレオニンおよびｌ−イソロイシンの製造法
JPS6214794A (ja) 1985-07-09 1987-01-23 Ajinomoto Co Inc 発酵法によるグアノシン及び／またはイノシンの製造法
JPS6230735A (ja) * 1985-08-02 1987-02-09 Meiji Seika Kaisha Ltd 新抗生物質ｓｆ−２４１８物質及びその製造法
JPS6234397A (ja) 1985-08-08 1987-02-14 Mitsubishi Electric Corp ダイナミツクメモリ装置
JPS62181281A (ja) * 1985-09-13 1987-08-08 ゲゼルシヤフト　ヒユア　ビオテクノロギツシエフオルシユング　ミツト　ベシユレンクテル　ハフツング 大環式抗生物質及びその製造方法
JPS6274293A (ja) 1985-09-28 1987-04-06 Kyowa Hakko Kogyo Co Ltd Ｌ−イソロイシンの製造法
JPS62195293A (ja) 1986-02-22 1987-08-28 Kyowa Hakko Kogyo Co Ltd 発酵法によるｌ−イソロイシンの製造法
JPS62244382A (ja) 1986-04-16 1987-10-24 Ajinomoto Co Inc 新規プロモーター及び該プロモーターを用いた遺伝子発現方法
JPS63214189A (ja) 1987-03-04 1988-09-06 Asahi Chem Ind Co Ltd Ｌ―グルタミン酸の製造方法
JPS63230094A (ja) 1987-03-18 1988-09-26 Kyowa Hakko Kogyo Co Ltd ５′−イノシン酸の製造法
KR890003681B1 (ko) 1987-03-26 1989-09-30 주식회사 미원 미생물에 의한 l-페닐 알라닌의 제조방법
JPS63240794A (ja) 1987-03-30 1988-10-06 Ajinomoto Co Inc Ｌ−トリプトフアンの製造法
JPS63248392A (ja) 1987-04-06 1988-10-14 Kyowa Hakko Kogyo Co Ltd 発酵法によるｌ−ロイシンの製造法
EP0331145A2 (en) 1988-03-04 1989-09-06 Kyowa Hakko Kogyo Co., Ltd. Process for producing amino acids
US5175107A (en) 1988-10-25 1992-12-29 Ajinomoto Co., Inc. Bacterial strain of escherichia coli bkiim b-3996 as the producer of l-threonine
WO1990004636A1 (fr) 1988-10-25 1990-05-03 Vsesojuzny Nauchno-Issledovatelsky Institut Genetiki I Selektsii Promyshlennykh Mikroorganizmov (Vniigenetika) Souche de bacteries escherichia coli, productrices de la threonine l
JPH02186994A (ja) 1989-01-13 1990-07-23 Ajinomoto Co Inc 発酵法によるｌ‐アミノ酸の製造法
JPH0358787A (ja) 1989-04-19 1991-03-13 Takeda Chem Ind Ltd Ｄｎａおよびその用途
JPH02303495A (ja) 1989-05-17 1990-12-17 Kyowa Hakko Kogyo Co Ltd 芳香族アミノ酸の製造法
WO1991008286A1 (fr) 1989-12-05 1991-06-13 Kyowa Hakko Kogyo Co., Ltd. Inosine guanosine kinase
JPH03216195A (ja) * 1990-01-22 1991-09-24 Ajinomoto Co Inc アミノ酸・核酸およびその誘導体の精製方法
JPH03232497A (ja) 1990-02-08 1991-10-16 Asahi Chem Ind Co Ltd 発酵法によるｌ―グルタミンの製造方法
JPH0428357A (ja) 1990-05-24 1992-01-30 Topcon Corp レーザ装置
JPH0488994A (ja) 1990-07-30 1992-03-23 Kyowa Hakko Kogyo Co Ltd 発酵法によるｌ―グルタミン酸の製造法
EP0488424A2 (en) 1990-11-30 1992-06-03 Ajinomoto Co., Inc. Recombinant DNA sequences encoding feedback inhibition released enzymes, plasmids comprising the recombinant DNA sequences, transformed microorganisms useful in the production of aromatic amino acids, and a process for preparing aromatic amino acids by fermentation
FR2669935A1 (fr) 1990-11-30 1992-06-05 Ajinomoto Kk Procede et appareil pour la regulation de la concentration de source de carbone dans la culture aerobie d'un micro-organisme.
US5912113A (en) 1990-11-30 1999-06-15 Ajinomoto Co., Inc. Method and apparatus for controlling carbon source concentration in aerobic cultivation of a microorganism
EP0488424B1 (en) 1990-11-30 1997-03-05 Ajinomoto Co., Inc. Recombinant DNA sequences encoding feedback inhibition released enzymes, plasmids comprising the recombinant DNA sequences, transformed microorganisms useful in the production of aromatic amino acids, and a process for preparing aromatic amino acids by fermentation
JPH04262790A (ja) 1991-02-19 1992-09-18 Kyowa Hakko Kogyo Co Ltd 発酵法による５’−キサンチル酸の製造法
US5658766A (en) 1991-05-30 1997-08-19 Ajinomoto Co., Inc. Strains of Escherichia coli which produce isoleucine or valine and a method for their production
JPH0592944A (ja) 1991-07-16 1993-04-16 Ajinomoto Co Inc アミノ酸・核酸またはその誘導体の製造方法
JPH0549489A (ja) 1991-08-22 1993-03-02 Ajinomoto Co Inc 発酵法によるｌ−フエニルアラニンの製造法
JPH05130882A (ja) 1991-11-11 1993-05-28 Kyowa Hakko Kogyo Co Ltd 発酵法によるｌ−イソロイシンの製造法
JPH05304971A (ja) * 1992-01-30 1993-11-19 Ajinomoto Co Inc Ｌ−フェニルアラニンの製造法
JPH0665314A (ja) 1992-01-31 1994-03-08 Spherilene Srl オレフィンの重合用の成分及び触媒
JPH05304969A (ja) 1992-02-25 1993-11-19 Kyowa Hakko Kogyo Co Ltd 発酵法によるアミノ酸の製造法
JP3225597B2 (ja) 1992-06-15 2001-11-05 味の素株式会社 発酵法によるｌ−フェニルアラニンの製造法
WO1994008031A1 (de) 1992-09-28 1994-04-14 Consortium für elektrochemische Industrie GmbH Mikroorganismen für die produktion von tryptophan und verfahren zu ihrer herstellung
US6180373B1 (en) 1992-09-28 2001-01-30 Consortium f{umlaut over (u)}r elektrochemische Industrie GmbH Microorganisms for the production of tryptophan and process for the preparation thereof
EP0593792A1 (en) 1992-10-14 1994-04-27 Ajinomoto Co., Inc. Novel L-threonine-producing microbacteria and a method for the production of L-threonine
US5354672A (en) 1992-11-24 1994-10-11 Ian Fotheringham Materials and methods for hypersecretion of amino acids
WO1995006114A1 (en) 1993-08-24 1995-03-02 Ajinomoto Co., Inc. Variant phosphoenolpyruvate carboxylase, gene thereof, and process for producing amino acid
EP0733712A1 (en) 1993-10-28 1996-09-25 Ajinomoto Co., Inc. Process for producing substance
US5830716A (en) 1993-10-28 1998-11-03 Ajinomoto Co., Inc. Increased amounts of substances by modifying a microorganism to increase production of NADPH from NADH
JPH07231793A (ja) 1993-12-27 1995-09-05 Ajinomoto Co Inc ヌクレオシド−５’−燐酸エステルの製造法
JPH10500002A (ja) * 1994-02-10 1998-01-06 バイオテクニカル リソーシス エル．ピー． 微生物におけるｌ−アスコルビン酸の生成
US5998178A (en) 1994-05-30 1999-12-07 Ajinomoto Co., Ltd. L-isoleucine-producing bacterium and method for preparing L-isoleucine through fermentation
EP0763127A1 (en) 1994-06-09 1997-03-19 Purdue Research Foundation Deblocking the common pathway of aromatic amino acid synthesis
WO1995034672A1 (en) 1994-06-14 1995-12-21 Ajinomoto Co., Inc. α-KETOGLUTARIC DEHYDROGENASE GENE
JPH0870879A (ja) 1994-06-30 1996-03-19 Kyowa Hakko Kogyo Co Ltd 発酵法によるｌ−ロイシンの製造法
WO1996006926A1 (fr) 1994-08-30 1996-03-07 Ajinomoto Co., Inc. Procede pour produire de la l-valine et de la l-leucine
WO1996030501A1 (en) 1995-03-24 1996-10-03 Ajinomoto Co., Inc. Process for producing nucleic acids
JPH08266295A (ja) 1995-03-30 1996-10-15 Ajinomoto Co Inc Ｌ−ロイシンの製造方法
JP2001245676A (ja) 1995-05-25 2001-09-11 Ajinomoto Co Inc 変異型酸性フォスファターゼ
WO1996037603A1 (fr) 1995-05-25 1996-11-28 Ajinomoto Co., Inc. Procede de production du nucleoside-5'-phosphate
WO1997008333A1 (fr) 1995-08-30 1997-03-06 Ajinomoto Co., Inc. Procede de production d'acides amines levogyres
EP0877090A1 (en) 1995-08-30 1998-11-11 Ajinomoto Co., Inc. Process for producing l-amino acids
US6319696B1 (en) 1995-08-30 2001-11-20 Ajinomoto Co., Inc. Process for producing L-amino acids
US5756345A (en) 1995-09-05 1998-05-26 Degussa Aktiengesellschaft Production of tryptophan by the bacterium Escherichia coli
JPH08168383A (ja) 1995-09-11 1996-07-02 Kyowa Hakko Kogyo Co Ltd 核酸関連物質の製造法
US6218168B1 (en) 1995-10-26 2001-04-17 CONSORTIUM FüR ELEKTROCHEMISCHE INUDSTRIE GMBH Process for preparing O-acetylserine, L-cysteine and L-cysteine-related products
US5763230A (en) 1996-03-22 1998-06-09 Triple-A B.V. P/A Produkschap Voor Veevoedor Amino acid fermentation processes
WO1998004715A1 (en) 1996-07-30 1998-02-05 Archer-Daniels-Midland Company Novel strains of escherichia coli, methods of preparing the same and use thereof in fermentation processes for l-threonine production
US5932453A (en) 1996-10-15 1999-08-03 Ajinomoto Co., Ltd. Process for producing L-amino acid through fermentation
JPH10201481A (ja) 1996-11-21 1998-08-04 Ajinomoto Co Inc ヌクレオシド−５’−燐酸エステルの製造法
US5972663A (en) 1997-06-19 1999-10-26 Consortium Fur Elektrochemische Industrie Gmbh Microorganisms and processes for the fermentative preparation of L-cysteine, L-cystine, N-acetylserine or thiazolidine derivatives
WO1999018228A2 (de) 1997-10-04 1999-04-15 Forschungszentrum Jülich GmbH Verfahren zur mikrobiellen herstellung von aminosäuren der aspartat- und/oder glutamatfamilie und im verfahren einsetzbare mittel
US6124121A (en) 1997-10-29 2000-09-26 Ajinomoto Co., Inc. Method for producing L-leucine
JPH11155571A (ja) 1997-11-25 1999-06-15 Ajinomoto Co Inc Ｌ−システインの製造法
EP0955368A2 (en) 1998-03-18 1999-11-10 Ajinomoto Co., Ltd. L-glutamic acid-producing bacterium and method for producing l-glutamic acid
EP0952221A2 (en) 1998-03-18 1999-10-27 Ajinomoto Co., Ltd. L-Glutamic acid-producing bacterium and method for producing L-glutamic acid
EP1070376A1 (de) 1998-04-09 2001-01-24 Siemens Aktiengesellschaft Anordnung und verfahren zur elektrischen energieversorgung einer elektrischen last
US6284495B1 (en) 1998-06-12 2001-09-04 Ajinomoto Co., Inc. Method for producing nucleic acid substances
EP0994190A2 (en) 1998-10-13 2000-04-19 Ajinomoto Co., Inc. DNA conferring L-homoserine resistance to bacteria, and its use
EP1013765A1 (en) 1998-12-23 2000-06-28 Ajinomoto Co., Ltd. Gene and method for producing L-amino acids
EP1016710A2 (en) 1998-12-30 2000-07-05 Ajinomoto Co., Inc. Method for producing L-amino acids
JP2000295996A (ja) 1999-02-08 2000-10-24 Kyowa Hakko Kogyo Co Ltd プリンヌクレオチドの製造法
WO2001002542A1 (fr) 1999-07-02 2001-01-11 Ajinomoto Co., Inc. Procede de production d'acide l-amine
WO2001002545A1 (fr) 1999-07-02 2001-01-11 Ajinomoto Co., Inc. Procede de production d'acide l-amine
US6403342B1 (en) 1999-07-09 2002-06-11 Anjinomoto Co., Inc. DNA coding for mutant isopropylmalate synthase L-leucine-producing microorganism and method for producing L-leucine
US6905819B1 (en) 1999-08-12 2005-06-14 Ajinomoto Co., Inc. Plasmid autonomously replicable in coryneform bacteria
EP1078989A2 (en) 1999-08-20 2001-02-28 Ajinomoto Co., Ltd. Method for producing L-glutamic acid by fermentation accompanied by precipitation
EP1092776A1 (en) 1999-10-14 2001-04-18 Ajinomoto Co., Inc. Method for producing L-amino acid by fermentation
WO2001027307A1 (de) 1999-10-14 2001-04-19 Consortium für elektrochemische Industrie GmbH Verfahren zur fermentativen herstellung von l-cystein oder l-cystein-derivaten
JP2001169788A (ja) 1999-10-27 2001-06-26 Degussa Huels Ag 分枝アミノ酸の排出をコードするヌクレオチド配列、その単離法および使用
JP2001346578A (ja) 2000-04-26 2001-12-18 Ajinomoto Co Inc アミノ酸生産菌及びアミノ酸の製造法
JP2002000289A (ja) 2000-06-23 2002-01-08 Ajinomoto Co Inc ヌクレオシド−５’−燐酸エステルの製造法
WO2002026993A1 (en) 2000-09-28 2002-04-04 Archer-Daniels-Midland Company Escherichia coli strains which over-produce l-threonine and processes for the production of l-threonine by fermentation
JP2002300887A (ja) 2001-02-05 2002-10-15 Ajinomoto Co Inc 発酵法によるｌ−グルタミンの製造法及びｌ−グルタミン生産菌
EP1239041A2 (en) 2001-02-13 2002-09-11 Ajinomoto Co., Inc. Method for producing L-amino acid using bacteria belonging to the genus Escherichia
EP1233068A2 (en) 2001-02-20 2002-08-21 Ajinomoto Co., Inc. Method for producing L-glutamic acid
US6596517B2 (en) 2001-02-20 2003-07-22 Ajinomoto Co., Inc. Method for producing L-glutamic acid
WO2003004598A2 (en) 2001-07-06 2003-01-16 Degussa Ag Process for the preparation of l-amino acids using strains of the enterobacteriaceae family
WO2003004664A2 (en) 2001-07-06 2003-01-16 Degussa Ag Process for the preparation of l-amino acids using strains of the enterobacteriaceae family with enhanced fba expression
WO2003008609A2 (en) 2001-07-18 2003-01-30 Degussa Ag Process for the preparation of l-amino acids using strains of the enterobacteriaceae family which contain an enhanced pykf gene
WO2003008611A2 (en) 2001-07-18 2003-01-30 Degussa Ag Process for the preparation of l-amino acids using strains of the enterobacteriaceae family which contain an enhanced talb gene
US20030157667A1 (en) 2001-11-23 2003-08-21 Ajinomoto Co., Inc. Method for producing L-amino acids using bacteria belonging to the genus escherichia
US20030148473A1 (en) 2001-11-23 2003-08-07 Ajinomoto Co., Inc. Method for producing L-amino acid using bacteria belonging to the genus escherichia
WO2003048374A1 (en) 2001-12-05 2003-06-12 Dsm Ip Assets B.V. Process for the production of an aromatic amino acid metabolite or derivative thereof
KR20030056490A (ko) 2001-12-28 2003-07-04 씨제이 주식회사 5'-크산틸산을 생산하는 미생물
JP2003219876A (ja) 2002-01-24 2003-08-05 Ajinomoto Co Inc プリンヌクレオシドおよびプリンヌクレオチドの製造方法
JP2004187684A (ja) 2002-11-26 2004-07-08 Ajinomoto Co Inc Ｌ−グルタミンの製造法及びｌ−グルタミン生産菌
US20040166575A1 (en) 2003-02-17 2004-08-26 Misa Tominaga Inosine producing bacterium belonging to the genus Bacillus and method for producing inosine
JP2004242610A (ja) 2003-02-17 2004-09-02 Ajinomoto Co Inc バチルス属に属するイノシン生産菌及びイノシンの製造法
WO2004090125A2 (en) 2003-04-07 2004-10-21 Ajinomoto Co., Inc. Method for producing l-amino acid using bacteria having enhanced expression of the gene pcka
EP1484410A1 (en) 2003-06-05 2004-12-08 Ajinomoto Co., Ltd. Fermentation methods and genetically modified bacteria with increased substrate and byproduct uptake.
JP3823099B2 (ja) 2003-06-26 2006-09-20 中日産業株式会社 キャリーカート
RU2003121601A (ru) 2003-07-16 2005-02-27 Закрытое акционерное общество "Научно-исследовательский институт "Аджиномото-Генетика" (ЗАО "АГРИ") (RU) Мутантная серинацетилтрансфераза
WO2005049808A1 (en) 2003-11-21 2005-06-02 Ajinomoto Co., Inc. Method for producing l-amino acid by fermentation
WO2005103275A1 (ja) 2004-04-26 2005-11-03 Ajinomoto Co., Ltd. 発酵法によるｌ－トリプトファンの製造法
EP1616940A1 (en) 2004-06-15 2006-01-18 Ajinomoto Co., Inc. L-tyrosine-producing bacterium and a method for producing L-tyrosine
WO2006070944A2 (en) 2004-12-28 2006-07-06 Ajinomoto Co., Inc. L-glutamic acid-producing microorganism and a method for producing l-glutamic acid
WO2006109830A1 (ja) 2005-04-12 2006-10-19 Kyowa Hakko Kogyo Co., Ltd. アミノ酸の製造法

Non-Patent Citations (21)

* Cited by examiner, † Cited by third party
Title
"Amino Acid Fermentation", 30 May 1986, GAKKAI SHUPPAN CENTER (LTD.), pages: 77 - 100
"Bacillus subtilis and Its Closest Relatives", 2002, ASM PRESS
"Bergey's Manual of Determinative Bacteriology", 1974, pages: 599
"Escherichia and Salmonella", 1996, ASM PRESS
"Experiments in Molecular Genetics", 1972, COLD SPRING HARBOR LABORATORY PRESS
"Kagaku Kogaku Binran", MARUZEN CO., LTD., pages: 1310 - 1311
APPL. MICROBIOL. BIOTECHNOL., vol. 42, 1994, pages 67 - 72
ARCH. MICROBIOL., vol. 149, 1988, pages 441 - 446
BIOSCI. BIOTECH. BIOCHEM., vol. 51, 1997, pages 840
BULLETIN OF THE CHEMICAL SOCIETY OF JAPAN, vol. 42, pages 3505
CHISTORERDOV, A.Y.; TSYGANKOV, Y.D., PLASMID, vol. 16, 1986, pages 161 - 167
EBBOLE D.J.; ZALKIN H., J. BIOL. CHEM., vol. 262, no. 17, 1987, pages 8274 - 87
EBBOLE, D.J.; H. ZALIKN, J. BIOL. CHEM., vol. 262, 1987, pages 8274 - 8287
FUJIMOTO, M.; UCHIDA, K., AGR. BIOL. CHEM., vol. 29, 1965, pages 249 - 259
INT. J. SYST. BACTERIOL., vol. 41, 1991, pages 255 - 260
LYNN, S.P. ET AL., MOL. BIOL., vol. 194, 1987, pages 59 - 69
MATSUYAMA, S.; MIZUSHIMA, S., J. BACTERIOL., vol. 162, 1985, pages 1196 - 1202
RES. MICROBIOL., vol. 154, 2003, pages 123 - 135
ROTH ET AL., METHODS ENZYMOL., vol. 51, 1978, pages 12 - 17
SWITZER ET AL., METHODS ENZYMOL., vol. 51, 1978, pages 3 - 11
UCHIDA, K. ET AL., AGR. BIOL. CHEM., vol. 25, 1961, pages 804 - 805

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2015091265A (ja) * 2008-10-29 2015-05-14 株式会社カネカ Ｌ−アミノ酸の製造方法
US9464306B2 (en) 2008-10-29 2016-10-11 Kaneka Corporation Method for producing L-amino acid

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