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WO2008101862A1 - Tube de perfusion - Google Patents

Tube de perfusion Download PDF

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Publication number
WO2008101862A1
WO2008101862A1 PCT/EP2008/051813 EP2008051813W WO2008101862A1 WO 2008101862 A1 WO2008101862 A1 WO 2008101862A1 EP 2008051813 W EP2008051813 W EP 2008051813W WO 2008101862 A1 WO2008101862 A1 WO 2008101862A1
Authority
WO
WIPO (PCT)
Prior art keywords
tube
head
orifices
forward end
tube according
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Ceased
Application number
PCT/EP2008/051813
Other languages
English (en)
Inventor
Philip Alan Visser
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Individual
Original Assignee
Individual
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Individual filed Critical Individual
Publication of WO2008101862A1 publication Critical patent/WO2008101862A1/fr
Anticipated expiration legal-status Critical
Ceased legal-status Critical Current

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61DVETERINARY INSTRUMENTS, IMPLEMENTS, TOOLS, OR METHODS
    • A61D7/00Devices or methods for introducing solid, liquid, or gaseous remedies or other materials into or onto the bodies of animals

Definitions

  • This invention relates to an infusing tube, also sometimes referred to as an infusing pipette.
  • the infusing tube is arranged to be used in cows and/or horses and arranged to deliver a drug or medicament thereto.
  • the uterus and cervix of animals may need to be treated due to the presence of conditions such as metritis and endometritis or because of infection. Trauma can be caused to the uterus and/or cervix during calving and such trauma can subsequently become infected. Administering antibiotic or disinfectant inside the uterus and cervix can treat these conditions. This has been found to be more effective than intra-muscular injection.
  • an infusing tube arranged to deliver a liquid into the uterus and/or cervix of a cow or horse
  • the infusing tube comprising: a length of flexible tube having a duct therethrough and having a forward end region arranged, in use, to be positioned within the uterus of a cow or horse and a rearward end region generally arranged to protrude from the cow or horse; the forward end region having a head, of larger diameter than the flexible tube, having a plurality of orifices therein which communicate with the duct of the tube.
  • Such a tube is advantageous as it may help to deliver liquids more effectively than prior art tubes.
  • the orifices in the head are arranged to spray liquid into the uterus in which the tube is, in use, inserted. Such spraying from a plurality of orifices can deliver the liquid more evenly over the interior of the uterus. Should the liquid be a medicament then the uterus may be treated more effectively than using prior art tubes.
  • the flexible nature of the tube allows the infusing tube to pass from the vaginal canal and through the cervical opening into the uterus .
  • the conditions that need to be treated by the liquid delivered may be present in both the uterus and cervix it is desirable for the liquid to be capable of flowing between the uterus and cervix.
  • the head is a separate member which is attached the flexible tube. Attachment may be by way of adhesive, welding (such as friction welding) or other suitable means.
  • the forward end of the head is curved.
  • Such an arrangement is advantageous as it can help to prevent damage to the vaginal, cervical and uteral tissue which may occur using tubes having squared-off ends.
  • the head may be egg shaped, preferably with the blunt end of the egg facing away from the flexible tube.
  • the head may comprise a portion of a tube of larger diameter than of the flexible tube. Such an arrangement may be simpler to manufacture than other embodiments .
  • the head may be ball shaped - i.e. it may be spherical or at least roughly spherical. Any suitable curve profile may be used for the head.
  • both the forward and rearward faces of the head are rounded. Rounding the rear face of the head may help to prevent damage to the cow or horse as the tube is retracted once the treatment has been finished.
  • the orifices may extend roughly perpendicularly from a plane passing along an axis of the duct within the tube. Such an arrangement is believed to be simpler to manufacture than other orientations of the orifices . The skilled person will appreciate the meaning of perpendicular but for the avoidance of doubt it is intended to mean at right angles to a plane.
  • the orifices may be arranged in rows around the circumference of the head; that is such as the orifices are provided in rings around the head.
  • the orifices within neighbouring rings may be offset from one another. Such an arrangement is convenient as it may provide for more even delivery of the fluid from the device. It is also believed that having orifices which extend substantially perpendicularly to the duct and/or the surface of the head can assist in the even delivery of the fluid.
  • the head may have at least one orifice in the forward end thereof. Again, such an arrangement is convenient for helping to ensure the even delivery of liquid into which the device has been inserted. There may be a plurality of orifices in the forward end region of the head.
  • the infusing tube is manufactured from a flexible material.
  • a flexible material is advantageous as it can make inserting the tube easier and less likely to damage the animal.
  • the material will generally be a plasties material. Materials such as Polyvinyl chloride (PVC) , Polycarbonate or polyethylene are likely to be suitable. Generally, the material will be of a medical grade.
  • the tube is likely to be arranged to be disposable.
  • the or each hole in the forward end of the head is of smaller diameter than any holes provided circumferentially around the head. Such an arrangement may help to increase the flow of liquid from any circumferentially placed holes by restricting the flow of liquid through the or each hole in the forward end of the head.
  • the hole in the forward end face is of smaller diameter than that of the duct passing through the tube.
  • the majority of the head of the tube is of solid material. Such an arrangement is convenient because it helps to prevent wastage of a liquid, such as a drug, which is delivered by the tube.
  • the volume of the duct through the tube and head may be of substantially a known volume.
  • a liquid such as a drug
  • This can be important when the amount of liquid needs to be controlled in order to deliver a known volume.
  • outer walls of the head taper, such that the diameter of the head decreases, from the forward end region towards the rearward end region.
  • Such an arrangement can help facilitate withdrawal of the infusing tube from the animal into which it is inserted.
  • the material from which the head is fabricated is of a softer material than that of the tube.
  • Such an arrangement can be advantageous as it can help to protect an animal into which the infusing tube is inserted and can also facilitate attaching the head to the flexible tube.
  • a pack comprising a plurality of tubes according to the first aspect of the invention.
  • the pack comprises roughly 5, 10, 15 , 20, 25 , 30 or 40 tubes (or any number in between these) .
  • the tubes within the pack may or may not be individually wrapped. Such wrapping may be arranged to keep the tube sterile which is advantageous as it helps to prevent the animal on which the tube is used becoming infected through use of the tube.
  • an infusing tube arranged to deliver a liquid into the uterus and/or cervix of a cow or horse
  • the infusing tube comprising: a body portion comprising a length of tube having a duct therethrough and having a forward end region arranged, in use, to be positioned within the uterus of a cow or horse and a rearward end region arranged to protrude from the cow or horse; the forward end region comprising a head having a plurality of orifices therein which communicate with the duct of the tube.
  • Figure 1 shows a cross section through a first embodiment of the invention
  • Figure 2 shows a cross section through a second embodiment of the invention
  • FIG. 3 schematically shows the second embodiment of Figure 2
  • Figure 4 schematically shows how liquid is ejected from the second embodiment
  • Figure 5 schematically shows a perspective view of a further embodiment
  • Figure 6 schematically shows a cross section along a centre line of the embodiment shown in Figure 5.
  • Figure 1 shows an infusing tube 2 according to one embodiment of the invention which comprises a tube 4, which is of a flexible material, having a forward end region 6.
  • the flexible tube may be thought of as a body portion of the infusing tube 2.
  • a duct 8 extends through the tube 4 and into the forward end region 8.
  • a head 10 provided at the forward end region 6 comprises a roughly egg shaped member having its blunt end 12 at a forward end 32 thereof; i.e. the end that is inserted into the vaginal tract of the animal.
  • the forward end of the head 10 is curved.
  • three rows a, b, c of orifices are shown.
  • the orifices 14 within each row of holes forms a ring around the circumference of the forward end region.
  • Figure 2 shows a second embodiment of the infusing tube 2.
  • like parts of the second embodiment have been referred to with like reference numbers. Again, it will be seen that the forward end of the head 10 is curved.
  • the head 10 of the forward end region 6 is provided by a portion of a tube of larger diameter than the tube 4 of the body portion.
  • the larger diameter tube is affixed to the smaller diameter tube by a means such as adhesive, welding or the like.
  • the tube of the head 10 has rounded corners 16 at a forward end thereof. Such rounded corners 16 help to reduce injuries to the animal into which the infusing tube is being inserted.
  • the flexible tube 4 of the body portion is roughly 5mm in diameter and the tube of the head 10 is roughly 10mm.
  • the tube 4 of the body portion may be roughly any of the following diameters: 3mm, 4mm, 6mm, 7mm, 8mm.
  • the tube of the head 10 may be roughly any of the following diameters: 6mm, 7mm, 8mm, 9mm, 10mm, 11mm, 12mmm, 13mm, 14mm, 15mm. It is perhaps convenient if the duct passing through the head and body portion is of as small a volume as practicable since this case make the delivery of a drug more accurate. If the volume is large then the amount of liquid (which might be a drug) delivered may be imprecise since a significant volume of liquid may remain in the duct. If an expensive drug is being used then it is particularly undesirable for the drug to be wasted in this manner.
  • the head is roughly 15mm to 20mm in length. However, in other embodiments, the head may have other lengths, perhaps in the range 5mm to 25mm or even 30mm.
  • Figure 3 shows a perspective view of the second embodiment highlighting the further rows of orifices d, e and also a rearward end region of the infusing tube 30.
  • the row of orifices d is positioned between rows a and b and the orifices are staggered (i.e. offset) such that an orifice in row d lies roughly midway between orifices in either row a or b.
  • row e is positioned between rows b and c and the orifices are staggered such that an orifice in row e lies roughly midway between orifices in either row b or row c.
  • Each of the rows of orifices a, b, c, d, e comprises 4 orifices and as such in this embodiment there are 21 orifices - there being a single orifice in the forward end of the head 10.
  • Other embodiments may have different numbers of orifices in each row of orifices and indeed there may be different numbers of rows of orifices.
  • Figure 4 schematically shows how a liquid may be ejected from the orifices of the tube 2. It will be seen that a liquid is ejected such that a large area is covered thereby thus helping to ensure that the liquid covers a large area of the uterus into which the head has been inserted.
  • the body portion of the tube 4 is long enough to extend through the vaginal tract of a horse/cow such that the head 10 can be inserted into the uterus thereof and an end region of the tube 4 distal that of the head 10 extends from the animal.
  • the tube 4 may generally be 50cm to 60cm in length.
  • a user will insert the head 10 of the tube 2 into the vaginal tract of the animal to be treated.
  • the tube 2 is then pushed along the vaginal tract and guided through the cervix into the uterus.
  • the user will have his/her arm in the animal's rectal canal to guide the tube through the vaginal tract.
  • the resistance to insertion of the tube 4 drops and as such the user may be able to determine that the tube 4 has entered the uterus.
  • the device may be pulled backwards once the head 10 has entered the uterus thus the portions of the egg shaped head 10, which is of larger diameter than the body portion, may be held against the cervical opening.
  • a temporary seal between the head 10 and the cervical opening may be formed which may help prevent any liquid injected into the animal from escaping.
  • FIGS. 5 and 6 show a further embodiment of an infusing tube and again like parts are referred to with like reference numerals.
  • the head 10 has a roughly hemispherical forward end face 60, which can be though of as being egg shaped. In this end face there is provided, at roughly a central region thereof, an orifice 62. From Figure 6, it can be seen that the diameter of the orifice 62 in the forward end face is of smaller diameter than the duct through the flexible tube 4. Likewise the diameters of the orifices 14 other than the one in the end face are of smaller diameter than the duct. However, it should be noted that the diameter of the orifice 62 in the end face is of smaller diameter than the ducts 14 which are circumferentially positioned around the head 10.
  • each row having four holes therein.
  • the holes in one of the rows are offset, by roughly 45°, from the holes in the other of the rows.
  • the rear face 64 of the head is also curved, so as to present a smooth rear face to assist removal of the infusing tube from an animal into which it has been inserted.
  • the outer walls of the head 10 taper slightly from forward face 60 toward the rear face 64. Also, it will be seen that the duct within the head 10 tapers from a diameter arranged to accept the flexible tube at a rear end region, to a smaller diameter toward a forward end region. Such an embodiment can be advantageous in order to reduce the volume of fluid that can be maintained within the infusing tube.

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Engineering & Computer Science (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Infusion, Injection, And Reservoir Apparatuses (AREA)

Abstract

L'invention concerne un tube de perfusion conçu pour administrer un liquide dans l'utérus et/ou dans le col de l'utérus d'une vache ou d'un cheval. Ce tube de perfusion comprend : une longueur de tube souple (4) présentant un conduit (8) le traversant et présentant une zone d'extrémité avant (6) conçue pour être positionnée, pendant son utilisation, à l'intérieur de l'utérus d'une vache ou d'un cheval, et une zone d'extrémité arrière généralement conçue pour faire saillie hors de la vache ou du cheval, la zone d'extrémité avant présentant une tête (10) dont le diamètre est plus grand que celui du tube souple (4), laquelle tête présentant une pluralité d'orifices (14) en communication avec le conduit (8) du tube souple (4).
PCT/EP2008/051813 2007-02-24 2008-02-14 Tube de perfusion Ceased WO2008101862A1 (fr)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GB0703639A GB0703639D0 (en) 2007-02-24 2007-02-24 Infusing Tube
GB0703639.5 2007-02-24

Publications (1)

Publication Number Publication Date
WO2008101862A1 true WO2008101862A1 (fr) 2008-08-28

Family

ID=37945687

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/EP2008/051813 Ceased WO2008101862A1 (fr) 2007-02-24 2008-02-14 Tube de perfusion

Country Status (2)

Country Link
GB (1) GB0703639D0 (fr)
WO (1) WO2008101862A1 (fr)

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
USD918388S1 (en) 2018-06-15 2021-05-04 Wiesman Holdings, LLC Solution diffusing head
US11207509B2 (en) 2017-06-15 2021-12-28 Wiesman Holdings, LLC Method and device for delivery of a solution into a body orifice

Citations (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE196469C (de) * 1907-06-08 1908-03-16 Vorfallgeschirrr zur Behandlung des Gebärmuttervofalles bei Kühen usw.
DE200944C (de) * 1907-06-08 1908-08-03 Vorfallgeschirr
CA2213252A1 (fr) 1995-12-18 1997-06-26 Manuel P. Botelho Pipette d'injection trans-uterine et son procede d'utilisation
WO1999043269A2 (fr) * 1998-02-25 1999-09-02 Bryher Holdings Limited Dispositif veterinaire d'administration de substances et procede correspondant
US20020193658A1 (en) * 2001-06-14 2002-12-19 Simmet Ludwig O. Device for sow intra-uterine insemination and embryo transfer

Patent Citations (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE196469C (de) * 1907-06-08 1908-03-16 Vorfallgeschirrr zur Behandlung des Gebärmuttervofalles bei Kühen usw.
DE200944C (de) * 1907-06-08 1908-08-03 Vorfallgeschirr
CA2213252A1 (fr) 1995-12-18 1997-06-26 Manuel P. Botelho Pipette d'injection trans-uterine et son procede d'utilisation
CA2213252C (fr) * 1995-12-18 2005-10-18 Manuel P. Botelho Pipette d'injection trans-uterine et son procede d'utilisation
WO1999043269A2 (fr) * 1998-02-25 1999-09-02 Bryher Holdings Limited Dispositif veterinaire d'administration de substances et procede correspondant
US20020193658A1 (en) * 2001-06-14 2002-12-19 Simmet Ludwig O. Device for sow intra-uterine insemination and embryo transfer

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US11207509B2 (en) 2017-06-15 2021-12-28 Wiesman Holdings, LLC Method and device for delivery of a solution into a body orifice
USD918388S1 (en) 2018-06-15 2021-05-04 Wiesman Holdings, LLC Solution diffusing head

Also Published As

Publication number Publication date
GB0703639D0 (en) 2007-04-04

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