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WO2008152653A3 - An improved process for the preparation of tamsulosin hydrochloride - Google Patents

An improved process for the preparation of tamsulosin hydrochloride Download PDF

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Publication number
WO2008152653A3
WO2008152653A3 PCT/IN2008/000367 IN2008000367W WO2008152653A3 WO 2008152653 A3 WO2008152653 A3 WO 2008152653A3 IN 2008000367 W IN2008000367 W IN 2008000367W WO 2008152653 A3 WO2008152653 A3 WO 2008152653A3
Authority
WO
WIPO (PCT)
Prior art keywords
improved process
preparation
tamsulosin hydrochloride
tamsulosin
hydrochloride
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Ceased
Application number
PCT/IN2008/000367
Other languages
French (fr)
Other versions
WO2008152653A2 (en
Inventor
Om Dutt Tyagi
Purna Chandra Ray
Konudula Babu Rao
Yogendra Kumar Chauhan
Bandlamudi Veera Narayana
Dosarala Siva Prasad Reddy
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Mylan Laboratories Ltd
Original Assignee
Matrix Laboratories Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Matrix Laboratories Ltd filed Critical Matrix Laboratories Ltd
Publication of WO2008152653A2 publication Critical patent/WO2008152653A2/en
Anticipated expiration legal-status Critical
Publication of WO2008152653A3 publication Critical patent/WO2008152653A3/en
Ceased legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C311/00—Amides of sulfonic acids, i.e. compounds having singly-bound oxygen atoms of sulfo groups replaced by nitrogen atoms, not being part of nitro or nitroso groups
    • C07C311/30—Sulfonamides, the carbon skeleton of the acid part being further substituted by singly-bound nitrogen atoms, not being part of nitro or nitroso groups
    • C07C311/37—Sulfonamides, the carbon skeleton of the acid part being further substituted by singly-bound nitrogen atoms, not being part of nitro or nitroso groups having the sulfur atom of at least one of the sulfonamide groups bound to a carbon atom of a six-membered aromatic ring
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C303/00—Preparation of esters or amides of sulfuric acids; Preparation of sulfonic acids or of their esters, halides, anhydrides or amides
    • C07C303/36—Preparation of esters or amides of sulfuric acids; Preparation of sulfonic acids or of their esters, halides, anhydrides or amides of amides of sulfonic acids
    • C07C303/40—Preparation of esters or amides of sulfuric acids; Preparation of sulfonic acids or of their esters, halides, anhydrides or amides of amides of sulfonic acids by reactions not involving the formation of sulfonamide groups
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07B—GENERAL METHODS OF ORGANIC CHEMISTRY; APPARATUS THEREFOR
    • C07B2200/00—Indexing scheme relating to specific properties of organic compounds
    • C07B2200/07—Optical isomers

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  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)

Abstract

The invention relates an improved process for preparing the (R)-(-)5-[2-[[2-(2-ethoxyphenoxyethyl]amino]propyl]-2-methoxybenzenesulfonamide of Formula (I): and its pharmaceutically acceptable salts.
PCT/IN2008/000367 2007-06-11 2008-06-10 An improved process for the preparation of tamsulosin hydrochloride Ceased WO2008152653A2 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
IN1205CH2007 2007-06-11
IN1205/CHE/2007 2007-06-11

Publications (2)

Publication Number Publication Date
WO2008152653A2 WO2008152653A2 (en) 2008-12-18
WO2008152653A3 true WO2008152653A3 (en) 2010-04-29

Family

ID=40130294

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/IN2008/000367 Ceased WO2008152653A2 (en) 2007-06-11 2008-06-10 An improved process for the preparation of tamsulosin hydrochloride

Country Status (1)

Country Link
WO (1) WO2008152653A2 (en)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN102898336B (en) * 2012-10-16 2013-11-27 北京悦康科创医药科技有限公司 Preparation method of tamsulosin hydrochloride

Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA1282077C (en) * 1985-11-13 1991-03-26 Kunihiro Niigata Process for producing substituted-phenethylamine derivatives
WO2003035608A1 (en) * 2001-10-25 2003-05-01 Leciva, A.S. A method of the preparation of (r)-(-)-5`2-`2-(2-ethoxyphenoxy) ethylamino! propyl!-2-methoxybenzenesulphonamide (tamsulosin)
WO2004087623A2 (en) * 2003-03-07 2004-10-14 Alembic Limited An improved process for the preparation of (r) (-) tamsulosin hydrochloride
EP1734036A1 (en) * 2005-06-14 2006-12-20 Well-being Biochemical Corp. Process for preparation of tamsulosin and its derivatives

Patent Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA1282077C (en) * 1985-11-13 1991-03-26 Kunihiro Niigata Process for producing substituted-phenethylamine derivatives
WO2003035608A1 (en) * 2001-10-25 2003-05-01 Leciva, A.S. A method of the preparation of (r)-(-)-5`2-`2-(2-ethoxyphenoxy) ethylamino! propyl!-2-methoxybenzenesulphonamide (tamsulosin)
WO2004087623A2 (en) * 2003-03-07 2004-10-14 Alembic Limited An improved process for the preparation of (r) (-) tamsulosin hydrochloride
EP1734036A1 (en) * 2005-06-14 2006-12-20 Well-being Biochemical Corp. Process for preparation of tamsulosin and its derivatives

Also Published As

Publication number Publication date
WO2008152653A2 (en) 2008-12-18

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