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WO2008148317A1 - Procédé de mesures autonomes du flux sanguin cérébral - Google Patents

Procédé de mesures autonomes du flux sanguin cérébral Download PDF

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Publication number
WO2008148317A1
WO2008148317A1 PCT/CN2008/070838 CN2008070838W WO2008148317A1 WO 2008148317 A1 WO2008148317 A1 WO 2008148317A1 CN 2008070838 W CN2008070838 W CN 2008070838W WO 2008148317 A1 WO2008148317 A1 WO 2008148317A1
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WO
WIPO (PCT)
Prior art keywords
blood flow
probe
flow signal
angle
motor
Prior art date
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Ceased
Application number
PCT/CN2008/070838
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English (en)
Chinese (zh)
Inventor
Xiaoyi Wang
Kai Wang
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SHENZHEN DELICATE ELECTRONICS CO Ltd
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SHENZHEN DELICATE ELECTRONICS CO Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
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Publication date
Application filed by SHENZHEN DELICATE ELECTRONICS CO Ltd filed Critical SHENZHEN DELICATE ELECTRONICS CO Ltd
Publication of WO2008148317A1 publication Critical patent/WO2008148317A1/fr
Anticipated expiration legal-status Critical
Ceased legal-status Critical Current

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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B8/00—Diagnosis using ultrasonic, sonic or infrasonic waves
    • A61B8/06—Measuring blood flow
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B8/00—Diagnosis using ultrasonic, sonic or infrasonic waves
    • A61B8/08—Clinical applications
    • A61B8/0808—Clinical applications for diagnosis of the brain

Definitions

  • the present invention relates to a cerebral blood flow detecting method, and more particularly to a method for automatically adjusting and detecting a cerebral blood flow detecting probe holder.
  • transcranial Doppler blood flow analyzer also known as “transcranial Doppler cerebral blood flow diagnostic system”, “transcranial Doppler detector”, “transcranial Doppler” Diagnosis and monitoring system “etc.” detection of cerebrovascular signals
  • TCD is a non-invasive medical device for the diagnosis and/or monitoring of intracranial and cervical vascular diseases in humans.
  • the probe In the clinical application of TCD, since the detection of blood flow signals is easily disturbed, the probe is adjusted to transmit ultrasonic waves to the patient.
  • the optimal position and angle of the head and neck is the key to successful diagnosis and monitoring, and is the most difficult place to operate throughout the clinical application.
  • Probe holder device As shown in FIG. 12, in the prior art head frame diagram, the probe holder 10a can be fitted to the head of the subject, and the probe holder 10a is provided with a fixed arm l la, which can usually be connected by bolts. It is fixed to the probe holder 10a (the probe is not shown, only the mounting hole 12a of the probe is shown).
  • the device has the characteristics of a patient suitable for different brain shapes and sizes; the device can fix the probe after manually finding the target blood vessel, eliminating long-distance operation (especially long-range monitoring).
  • the hand-held probe is easily trembled. Any small movements, such as speech, which are susceptible to fatigue and the resulting signal instability.
  • the process of finding the target vessel position is still all manual operation, and the blood flow signal will change after the probe is displaced by the vibration caused by various reasons during the monitoring process after the probe is fixed. Weak or even disappear.
  • there are obvious shortcomings in the probe adjustment method of the probe holder on the market which are mainly reflected in:
  • An object of the present invention is to provide a method for automatically detecting cerebral blood flow.
  • the probe By setting a judgment and adjustment of a blood flow signal by a single-chip microcomputer, the probe can be automatically controlled to adjust the detection position.
  • a method for automatically detecting cerebral blood flow comprising the steps of:
  • A Set the optimal position and angle of the probe
  • [14] B According to the position and angle of the probe, the current blood flow signal parameter is obtained, and it is determined whether the current blood flow signal parameter is the optimal blood flow signal parameter, and if so, the current blood flow signal parameter is saved as the most Good blood flow signal parameters, and save the position and angle of the probe as the optimal position and angle of the probe;
  • the step B includes the following steps:
  • step B1 determining whether the position and angle of the probe change by detecting blood flow signal parameters, and if yes, proceeding to step B2;
  • [18] B2 acquiring a next scanning point of the probe, and adjusting the probe to the scanning point;
  • [19] B3 acquiring a current blood flow signal parameter of the scan point, and determining whether the current blood flow signal parameter is an optimal blood flow signal parameter, and if yes, saving the current blood flow signal parameter as an optimal blood Stream signal Count and save the position and angle of the probe for the optimal position and angle of the probe; otherwise, repeat step B2 and step B3.
  • the step A includes: A1: moving the probe to an arbitrary position, and setting a blood flow signal parameter of the position detected by the probe to an optimal blood. Flow signal parameters and set the position to the optimal position and angle of the probe;
  • [21] A2 Determine whether the next scan point is successfully obtained. If the acquisition is successful, move the probe to the scan point, then perform step B until the detection of all scan points is completed, and then perform step C.
  • the method is applied to a transcranial Doppler blood flow analyzer, and the probe of the transcranial Doppler blood flow analyzer is placed on a probe holder, and one is set for A microcontroller that controls the position and angle of the probe;
  • step A first setting an optimal blood flow signal parameter, wherein the optimal blood flow signal parameter is a blood flow signal intensity threshold value that is pre-specified;
  • step B monitoring the current blood flow signal parameter obtained by the probe as a blood flow signal intensity threshold
  • step C by controlling a plurality of driving motors, adjusting the position and angle of the probe, and performing a comparison between monitoring the blood flow signal and the blood flow signal intensity threshold until the blood flow signal detection is satisfied.
  • step C further includes:
  • the driving motor comprises two angle-adjusting angle motors, and three adjusting positions of the azimuth motor; the angle motor pulls the probe rear end by a pull rod, and the probe front end is disposed on the elastic damping portion;
  • the angle motor and the probe are arranged as an angle adjustment module, and the azimuth motor is arranged to drive the spatial displacement of the angle adjustment module.
  • step C further includes:
  • step C further includes:
  • the MCU controls the motor to rotate forward and backward, respectively, centering on the current position of the two angle motors, and the blood flow in the four directions is obtained.
  • the detection signal parameter is compared with the blood flow detection signal intensity threshold to determine whether the blood flow detection requirement is met.
  • the driving motor is a servo motor
  • the motor control process realized by the single chip microcomputer realizes forward or reverse rotation
  • the motor control process includes a rotation speed control of the driving motor and a motor driving. Output and position determination.
  • the speed control process includes:
  • A1-1 periodically obtain the position of the drive motor and define it as the current position
  • the current motion rate and the programmed rate are defined as the set speed to compare whether the current rate meets the setting requirement. If the speed is too slow, increase the speed; if the speed is too fast, Reduce the speed; if the speed and set value are always, keep the speed.
  • the location determination process includes:
  • the invention provides a method for automatically detecting cerebral blood flow, and uses a controller to control the blood flow signal, and automatically adjusts the probe according to the detection result of the TCD, and automatically adjusts the probe. It realizes the automatic recovery of blood flow signal detection, which can be applied to the occasion of long daytime monitoring, and increases the range of use of TCD.
  • FIG. 1 is a schematic flow chart of realizing automatic tracking in a method for automatically detecting cerebral blood flow according to the present invention
  • FIG. 2 is a schematic flow chart of realizing automatic scanning and the like in the method for automatically detecting cerebral blood flow according to the present invention
  • FIG. 3 is a schematic diagram of a control flow of a method for automatically detecting cerebral blood flow according to the present invention.
  • FIG. 4 is a schematic view showing the trajectory of two driving motors for tracking vasospasm in the method of the present invention
  • FIG. 5 is a schematic diagram showing the structure of an automatic adjustment probe for automatically detecting cerebral blood flow according to the present invention.
  • FIG. 6 is a schematic view showing the structure of an automatic adjustment probe for automatically detecting cerebral blood flow according to the present invention.
  • FIG. 7 is a schematic diagram showing the operation of the blood flow signal module of the method of the present invention.
  • FIG. 8 is a schematic diagram showing the operation of the entire system of the present invention.
  • FIG. 9 is a schematic diagram of a single-chip control instruction of the method of the present invention.
  • FIG. 10 is a schematic diagram of a speed control process of the method of the present invention.
  • FIG. 11 is a schematic diagram of a motor control flow in a position determination process of the method of the present invention.
  • FIG. 12 is a schematic structural view of a prior art probe holder.
  • the method of the present invention is used for automatically monitoring cerebral blood flow, and can realize functions such as automatic scanning, directional scanning, automatic searching, and automatic tracking.
  • the method mainly comprises the following steps: first setting an optimal blood flow signal parameter and an optimal position and angle of the probe; then obtaining a current blood flow signal parameter according to the position and angle of the probe, and determining the current blood flow signal parameter Whether it is the optimal blood flow signal parameter, if yes, save the current blood flow signal parameter as the optimal blood flow signal parameter, and save the probe position and angle as the optimal position and angle of the probe; finally, adjust the probe To the best position and angle as described.
  • the automatic tracking refers to performing automatic tracking after obtaining the precise position of the blood vessel by automatic scanning or directional scanning or automatic searching or manual searching; automatically tracking through the blood flow signal after various external factors cause slight change of the probe position or angle
  • the algorithm detects the change; after detecting the change, the system slightly adjusts the position and angle of the probe, and simultaneously tracks the change of the signal to determine whether it matches the signal before the change, and stops the position and angle adjustment of the probe after detecting the coincidence signal; Spiral scanning from the center outward or by raster scanning [58] Specifically, the blood flow signal is first detected, and blood flow signal parameters, such as blood flow signal intensity, blood flow index, continuous daytime, etc.
  • the position and angle of the probe are determined according to the blood flow signal parameter. Whether there is a change, for example, when the current blood flow signal parameter is compared with the optimal blood flow signal parameter, the variation range exceeds the set value, and the continuous daytime exceeds a certain time, the position and angle of the probe are changed, otherwise it is determined as No change has taken place. After it is determined that the probe position and angle have not changed, it is judged whether the tracking setting has been manually stopped, and then it is ended, otherwise the blood flow signal parameter is continuously monitored.
  • the next scan point and adjust the probe to the scan point obtains the next scan point and adjust the probe to the scan point.
  • the acquisition of the next scan point can be obtained by an external spiral method or a raster scan method.
  • the blood flow signal parameter of the scanning point is obtained by the probe, and whether the probe position and the angle return to normal according to the blood flow signal parameter, for example, the blood flow signal parameter of the scanning point is compared with the optimal blood flow signal parameter, The range of variation within the daytime is within the set value range, and the probe position and angle are restored to the normal position; then, the blood flow signal parameters and the probe position and angle of the scan point are saved, and then the blood flow signal is continuously monitored; If it does not return to the normal position, it is judged whether to stop the tracking manually, if it stops, it ends, otherwise it returns to step #, continues to adjust to the next scanning point, and scans until it is judged that the probe position returns to normal.
  • the probe is manually moved to an arbitrary position, and the blood flow signal parameter detected by the probe at the position is set as the optimal blood flow signal parameter, and the position is set as the probe. Best position and angle.
  • All the scanning points in the setting area when all the scanning points have been detected by the probe, it is judged that the next scanning point cannot be obtained, and then the scanning is finished, the probe is adjusted to the optimal position and angle; otherwise, it is judged to be able to obtain Next scan point, then move the probe to the scan point, detect the blood flow signal parameter of the scan point as the current blood flow signal parameter; then determine whether the current blood flow signal parameter is better than the optimal blood flow signal parameter, and if so, Save the current blood flow signal parameters as the optimal blood flow signal parameters, and Save the current probe position as the optimal position and angle of the probe; otherwise, continue to determine if the next scan point can be obtained until all scan points are detected and adjust the probe to the optimal position and angle of the probe.
  • the comparison between the current blood flow signal parameter and the optimal blood flow signal parameter may be in any of the following manners; of course, those skilled in the art may also compare the blood flow signal parameters. Any other parameters are used for judgment, and are not listed here.
  • the difference between I, RI, HR, etc. determines whether the predetermined amplitude is exceeded, and determines whether the continuous daytime exceeds the predetermined time, and determines whether the position and angle of the probe change, thereby obtaining whether the current blood flow signal is the optimal blood flow signal.
  • the real DOP blood flow index (Peak, Means Dias, PI, RI, HR, etc.) The difference between the predetermined DOP blood flow index (Peak, Means Dias, PI, RI, HR, etc.), whether the two exceed the predetermined amplitude and whether the continuous daytime exceeds the predetermined time, and whether the probe position and angle are judged. A change occurs to determine whether the current blood flow signal is the optimal blood flow signal.
  • the method for automatically detecting cerebral blood flow of the present invention is shown below, as shown in Fig. 3, which is used in an application example of a transcranial Doppler blood flow analyzer.
  • the probe 110 of the transcranial Doppler blood flow analyzer is placed on a probe holder, as shown in FIG. 5 and FIG. 6, and a controller is provided (here, the single chip microcomputer 100, of course, can also be other forms of control. , such as logic circuits, integrated circuits, etc., are used to control the adjustment of the probe 110.
  • the adjustment process at least includes: predetermining the detected blood flow signal intensity threshold for comparing whether the blood flow signal intensity detected at a certain position satisfies the requirement; and then monitoring the blood flow signal at a certain position, and the blood flow signal intensity
  • the threshold is compared, if the threshold is lower, an instruction for adjusting the position and angle of the probe is issued; the command for adjusting the position and angle of the probe issued by the single chip can control a plurality of driving motors, and the plurality of driving motors can adjust the position of the probe 110 Position and angle, and in turn for each position
  • the detection signal is compared with the blood flow signal intensity threshold until the blood flow signal detection requirement is met
  • the driving motor used in the present invention comprises at least two angle-adjusting angle motors 130, and three adjustment positions of the azimuth motors 1, 2, 3, as shown in FIGS. 5 and 6;
  • the first end of the probe 110 is pulled by rotating the blade 1 31 and the pull rod, and the front end of the probe 110 is disposed on the elastic damper portion 120.
  • the angle motor 130 and the probe 110 may be disposed as an angle adjustment module 140, and the position motor 1, 2, 3 is configured to drive the angle adjustment module to move in a space outside the surface to be tested 210.
  • the above adjustment of the position and angle needs to be realized by the control of the single chip microcomputer 100.
  • the method for automatically detecting cerebral blood flow of the present invention is preferably adjusted manually, set to a position that can be measured, and then, during monitoring or measurement, when the detection signal becomes weak , automatic control adjustment is possible.
  • the so-called automatic control means that the controlled object or process is automatically carried out according to predetermined requirements by the controller without direct participation of the person.
  • an actuator refers to a device composed of a dual motor for controlling the position of the probe, and the adjusted (or controlled) object is a probe, and the source of the command for adjusting the control For the microcontroller.
  • the transcranial Doppler blood flow analyzer having the single-chip microcomputer is provided with a 'monitoring blood flow signal, a module and a 'calculating probe position angle' module for monitoring and reaction calculation, respectively.
  • a reference blood flow signal intensity threshold Ir is given, for example, a signal intensity value that is manually adjusted to be the strongest blood flow signal; and then according to transcranial Doppler blood flow analysis
  • the 'Calculate Probe Position Angle' module determines the rotation of the motor based on the value of Id: When the Id is not less than the threshold value, the motor maintains the original position without any rotation operation (ie, the position and direction change information of the motor that needs to be rotated remains unchanged. When the Id is less than the threshold zero, the 'calculate probe position angle' module converts the Id value into the position and direction change information that the motor needs to rotate, and transmits the result to the controller (for at least two motors for controlling the probe) Location device).
  • the controller rotates the motor to the specified target position, thereby adjusting the probe connected to the motor to the designated position, and finally adjusting the position and angle of the probe.
  • the azimuth motors 1, 2, 3 As shown in Fig. 6 for control.
  • the method for automatically detecting cerebral blood flow of the present invention realizes the function of automatically finding and retrieving (target) blood vessels by automatically adjusting the position and angle of the probe controlled by the single chip microcomputer.
  • the controller ie, the actuator
  • the process of automatically adjusting the direction and position of the motor by the system is: when searching for a vascular sputum using a raster scanning mode, the so-called search for a blood vessel refers to a manual search without prior manual search. Positioning, but the system operates completely independently, and finds the blood flow signal that meets the detection requirements by itself. Therefore, the probe needs to perform a large range of mobile positioning within a certain range. And the search process needs to follow certain movement rules, such as traversing all the outlets in a certain range according to the grid method.
  • the step size is S, where D is the displacement distance.
  • X belongs to any value in (Dlmin, Dlmax) and y belongs to any value in (D2min, D2 max)
  • the system can move the probe to the raster scan (ie, from left to right, top to bottom). All possible dot positions (x, y), then compare the blood flow signal strength at each location to determine whether the blood flow signal strength requirements are met, and find the appropriate probe target angle and direction.
  • the system adjusts the motor direction and position as follows: Centering on the current position of the two motors, respectively, sequentially forwards And rotate the motor backwards, as shown in Figure 6, and then compare the blood flow signal parameters in the four directions A, B, C, D with the threshold to find the target angle and direction of the probe that meets the requirements.
  • the number of rotations and the rotation distance can be adjusted as needed.
  • the adjustment rotation distance is smaller than the above-described step size S, and the search for the flaw is small-range and partial.
  • Both the tracking blood vessel and the search blood vessel are pitch angle control, except that the range of rotation of the latter electrode is the entire effective range, and the former is the current position.
  • the heart is offset by a fixed distance (usually the step size), ie only once in each direction. The positional movement is relative to the center of the probe, not the true translation. Because when turning (pitching) the probe ⁇ , the center position will also have a small offset.
  • the working principle of detecting the blood flow signal module in the method of the present invention includes: a blood flow signal (modulated onto an ultrasonic carrier) is converted into an electrical signal by piezoelectrically converting the wafer, and then passes through The digital blood flow signal is obtained by preamplification, demodulation, filtering, sample/holding, etc. Finally, the blood flow signal strength parameter If is obtained by digital signal processing technology (such as high-pass filtering, FFT fast Fourier transform algorithm).
  • digital signal processing technology such as high-pass filtering, FFT fast Fourier transform algorithm.
  • the invention automatically detects cerebral blood flow, and implants a probe adjusting mechanism on the probe frame, and the TCD main body is connected to the probe and the probe frame through a cable, and the probe is mounted on the adjusting mechanism, and the structure principle is See Figure 5 and Figure 6.
  • the MCU for control and the corresponding software system are configured in the TCD host, for example, adding recognition and analysis processing functions to the original TCD dedicated software platform.
  • the probe holder is manually installed, and after manually adjusting to the optimal detection position by the mechanical adjustment device on the probe holder (this part of the technology is similar to the existing headstock technology), the host system memorizes the signal strength of the cymbal and sets it to The initial value, that is, the blood flow signal intensity threshold used for reference; during the detection process, the host system synchronizes the analysis and comparison of the received detection signals.
  • the initial value that is, the blood flow signal intensity threshold used for reference
  • the host system synchronizes the analysis and comparison of the received detection signals.
  • the host feeds back information to the hardware control.
  • the system the control circuit sends an adjustment command to drive the micro servo motor, and the motor drives the adjustment mechanism to repeatedly adjust the position and angle of the probe until the signal strength is restored to the preset value.
  • the schematic block diagram is shown in Figure 8.
  • the system periodically scans the received signal and analyzes and calculates the waveform of the signal.
  • a range ⁇ this The range can be set in advance
  • the system feeds back information to the control chip of the control circuit, and controls The chip will execute the program of writing, and the control signal will drive the motor through the sequencing circuit, that is, three kinds of control commands are issued to the motor through the decoder: motor address code, motor steering code, motor rotation amplitude code
  • the motor selection, motor steering and rotation amplitude are controlled separately, and the adjustment mechanism adjusts the motion accordingly.
  • the position and angle of the probe are changed.
  • the new probe signal is fed back to the host.
  • the system periodically scans and compares the newly received blood flow signal again. If the blood flow signal is still not ideal, the second cycle is issued. The adjustment command until the detected blood flow signal meets the detection requirements.
  • the adjusting mechanism is realized by using a servo motor to drive a connecting rod mounted on the motor, and the probe is mounted on the other end of the metal shaft.
  • the connecting rod carries the end of the probe together in the motor.
  • the direction of rotation of the probe is changed in the forward or reverse direction, which is structurally easy to implement.
  • the invention can configure a plurality of motors and connecting rods to realize position adjustment and angle adjustment of the probe in multiple directions and multiple dimensions.
  • the servo motor realizes forward or reverse rotation through the motor control device.
  • the motor control device controls the motor rotation through three modules: speed control, motor drive output and position determination, which are described as follows:
  • the speed control periodically acquires the position of the motor (defined as the current position) and compares the current position with the position acquired in the previous cycle (defined as the last position) to obtain the motor's moving distance in one cycle. , that is, the motor's motion rate (current speed). The rate is compared with the programmed rate (defined as the set speed) to determine whether the current rate meets the set requirement. If the speed is too slow, increase the speed; if the speed is too fast, decrease the speed; Keep the speed in accordance with the set value.
  • the specific process is shown in Figure 10. Acceleration or deceleration is achieved by the motor drive output, which is accomplished by outputting the motor control signal to the motor's control input.
  • the process of position determination periodically acquires the position of the motor (defined as the current position), and compares the current position with the programmed position (defined as the target position), thereby obtaining the distance from the target position.
  • the difference (defined as the target distance difference); this difference is compared with the programmed stop distance. If the target distance difference is greater than the stop distance, the motor moves at the normal speed; otherwise, the set speed of the motor is reduced.
  • the specific process is shown in Figure 11.
  • the method for automatically detecting cerebral blood flow of the invention utilizes feedback, identification, and tracking of the detection signal, and adjusts the probe on the probe frame by controlling the motor in sequence, thereby realizing the automatic control process of the probe device.
  • the signal feedback and recognition are used to control the actuator, so that the position and angle of the probe are automatically adjusted, and a satisfactory blood flow detection signal can be obtained.
  • the signal processing method and algorithm of the method of the invention are relatively simple, so the processing speed is fast and the sensitivity is high. .
  • the probe holder or the like detecting device uses the control method provided by the present invention, and after the detection starts to adjust the detection position, the detecting device can automatically determine the strength of the signal and automatically adjust. Instead of manual operations, reduce human intervention.
  • the method of the invention can realize automatic and real adjustment: even if the signal quality is degraded or lost, the method of the invention can automatically respond, and correct, improve, and substantially eliminate the cumbersome operation of manually re-finding the signal; Under the condition of long daytime monitoring, no human attention is required, the inconvenience and troubles of the user are reduced, and the signal continuity is good, which has important clinical value in long-term monitoring, intensive care and thrombus detection;
  • the dependence of the probe holder on the degree of mechanical fixation of the wearer is weakened, which greatly reduces the pain and discomfort of the patient because the probe holder is too tight.
  • TCDs to assist in the diagnosis of symptoms require long-term continuous monitoring, such as intensive care and thrombus testing. Any one of the tested patients, such as coughing, turning over, etc., may affect the signal collection. .
  • the cumbersomeness of the medical staff needs to be greatly avoided, and the quality is more conducive to the collection of high-quality continuity of signals and data, which is conducive to diagnosis.
  • control circuit board of the control system in the above embodiments of the present invention can be mounted on the probe holder. It can also be installed in the TCD mainframe; the control system is a servo motor system, and other types of motors such as stepping motors can also be used, the difference is that the control precision is different. Further, the main element for controlling the operation can also be realized by using a hydraulic element or the like.
  • the monitored blood flow intensity parameter can be replaced by other forms of signals that can effectively reflect changes in blood flow, such as energy, amplitude, etc. of the blood flow signal, and preamplification, demodulation, filtering, ⁇ The order of processing, such as holding, is variable, for example, before demodulation.
  • digital signal processing can be implemented in software or in hardware or firmware. In digital signal processing, high-pass filtering is optional.
  • the threshold used for comparison with the difference Id in the comparison section may be other values (not necessarily 0). and many more.

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Abstract

L'invention concerne un procédé de mesures autonomes du flux sanguin cérébral, comprenant les étapes suivantes : fixation de la position et de l'angle optimaux de la sonde, acquisition des paramètres du signal de flux sanguin courant fondé sur la position et l'angle de la sonde, détermination permettant de savoir si ces paramètres de signal de flux sanguin courants sont les paramètres optimaux du flux sanguin, et sauvegarde des paramètres courants du signal de flux sanguin courant comme paramètres optimaux du flux sanguin et sauvegarde de la position et de l'angle de la sonde comme position et angle de sonde optimaux si ces paramètres sont les paramètres optimaux, réglage de la sonde et de la position et de l'angle optimaux.
PCT/CN2008/070838 2007-06-01 2008-04-29 Procédé de mesures autonomes du flux sanguin cérébral Ceased WO2008148317A1 (fr)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
CN200710074716.6 2007-06-01
CN2007100747166A CN101313855B (zh) 2007-06-01 2007-06-01 一种用于自动检测脑血流的方法

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WO2008148317A1 true WO2008148317A1 (fr) 2008-12-11

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CN114366163A (zh) * 2022-01-11 2022-04-19 深圳市德力凯医疗设备股份有限公司 基于快速扫描的脑血流数据采集方法、系统及智能终端

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CN103330575A (zh) * 2013-06-27 2013-10-02 苏州边枫电子科技有限公司 基于超声波检测的血流检测装置
CN103431877B (zh) * 2013-09-04 2015-04-15 中国科学院深圳先进技术研究院 脑血流检测探头支架
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CN107137110A (zh) * 2017-07-06 2017-09-08 郑州信翰科技有限公司 脑血管超声彩色多普勒分析仪的项圈式可穿戴探头
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