[go: up one dir, main page]

WO2008143342A1 - Method for producing 3-amino-2,5-dioxopyrrolidine derivative - Google Patents

Method for producing 3-amino-2,5-dioxopyrrolidine derivative Download PDF

Info

Publication number
WO2008143342A1
WO2008143342A1 PCT/JP2008/059505 JP2008059505W WO2008143342A1 WO 2008143342 A1 WO2008143342 A1 WO 2008143342A1 JP 2008059505 W JP2008059505 W JP 2008059505W WO 2008143342 A1 WO2008143342 A1 WO 2008143342A1
Authority
WO
WIPO (PCT)
Prior art keywords
amino
producing
dioxopyrrolidine derivative
dioxopyrrolidine
derivative
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Ceased
Application number
PCT/JP2008/059505
Other languages
French (fr)
Japanese (ja)
Inventor
Michinari Nishizuka
Koichiro Nishimura
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Kyowa Hakko Bio Co Ltd
KH Neochem Co Ltd
Sumitomo Pharma Co Ltd
Original Assignee
Kyowa Hakko Kogyo Co Ltd
Sumitomo Dainippon Pharma Co Ltd
Kyowa Hakko Bio Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Kyowa Hakko Kogyo Co Ltd, Sumitomo Dainippon Pharma Co Ltd, Kyowa Hakko Bio Co Ltd filed Critical Kyowa Hakko Kogyo Co Ltd
Priority to JP2009515279A priority Critical patent/JPWO2008143342A1/en
Publication of WO2008143342A1 publication Critical patent/WO2008143342A1/en
Anticipated expiration legal-status Critical
Ceased legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D207/00—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D207/02—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D207/30—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members
    • C07D207/34—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D207/36—Oxygen or sulfur atoms
    • C07D207/40—2,5-Pyrrolidine-diones
    • C07D207/416—2,5-Pyrrolidine-diones with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to other ring carbon atoms

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pyridine Compounds (AREA)
  • Pyrrole Compounds (AREA)

Abstract

Disclosed is a method for efficiently producing a 3-amino-2,5-dioxopyrrolidine derivative, which is useful as a synthesis intermediate for pharmaceutical products, without protecting an amino group. Specifically disclosed is a method for producing a 3-amino-2,5-dioxopyrrolidine derivative represented by the following reaction formula.
PCT/JP2008/059505 2007-05-23 2008-05-23 Method for producing 3-amino-2,5-dioxopyrrolidine derivative Ceased WO2008143342A1 (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
JP2009515279A JPWO2008143342A1 (en) 2007-05-23 2008-05-23 Method for producing 3-amino-2,5-dioxopyrrolidine derivative

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
JP2007-136649 2007-05-23
JP2007136649 2007-05-23

Publications (1)

Publication Number Publication Date
WO2008143342A1 true WO2008143342A1 (en) 2008-11-27

Family

ID=40032024

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/JP2008/059505 Ceased WO2008143342A1 (en) 2007-05-23 2008-05-23 Method for producing 3-amino-2,5-dioxopyrrolidine derivative

Country Status (2)

Country Link
JP (1) JPWO2008143342A1 (en)
WO (1) WO2008143342A1 (en)

Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPH06192222A (en) * 1992-12-25 1994-07-12 Dainippon Pharmaceut Co Ltd Succinic acid imide derivative
JP2000514436A (en) * 1996-07-10 2000-10-31 ノバルティス アクチエンゲゼルシャフト Functionalized ferrocenyl diphosphines, their preparation and uses
JP2001055366A (en) * 1999-08-12 2001-02-27 Kissei Pharmaceut Co Ltd Biarylacetic amide derivative
WO2004103984A1 (en) * 2003-05-26 2004-12-02 Wilex Ag Hydroxyamidine and hydroxyguanidine compounds as urokinase inhibitors

Patent Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPH06192222A (en) * 1992-12-25 1994-07-12 Dainippon Pharmaceut Co Ltd Succinic acid imide derivative
JP2000514436A (en) * 1996-07-10 2000-10-31 ノバルティス アクチエンゲゼルシャフト Functionalized ferrocenyl diphosphines, their preparation and uses
JP2001055366A (en) * 1999-08-12 2001-02-27 Kissei Pharmaceut Co Ltd Biarylacetic amide derivative
WO2004103984A1 (en) * 2003-05-26 2004-12-02 Wilex Ag Hydroxyamidine and hydroxyguanidine compounds as urokinase inhibitors

Also Published As

Publication number Publication date
JPWO2008143342A1 (en) 2010-08-12

Similar Documents

Publication Publication Date Title
WO2007125547A3 (en) Novel process for statins and its pharmaceutically acceptable salts thereof
WO2010062590A3 (en) Process for the preparation of protected l-alanine derivatives
EP2460797A3 (en) Process for preparation of ivabradine hydrochloride
WO2009036281A3 (en) Bortezomib and process for producing same
WO2009125992A3 (en) Vector for transformation using transposons, microorganisms transformed by the vector, and method for producing l-lysine using the same
WO2010031720A3 (en) Novel antibody formulation
UA102817C2 (en) Normal;heading 1;heading 2;heading 3;PROCESS FOR AGOMELATINE SYNTHESIS
WO2010048477A3 (en) Improved process for preparation of coupled products from 4-amino-3-cyanoquinolines using stabilized intermediates
WO2010015657A3 (en) Alkoxypyrazoles and the process for their preparation
UA102220C2 (en) Normal;heading 1;heading 2;heading 3;PROCESS FOR THE SYNTHESIS OF AGOMELATINE
WO2009123704A3 (en) Process for preparing bis(thiohydrazide amides)
WO2010076810A3 (en) A process for the preparation of gefitinib
WO2010059297A3 (en) Processes using molecular sieve ssz-82
WO2009055289A3 (en) Therapeutic substituted lactams
WO2009053446A3 (en) Pregabalin intermediates and process for preparing them and pregabalin
WO2010120058A3 (en) Novel cyanine compound for labelling biomolecules, and preparation method thereof
WO2008021491A3 (en) Method for synthesis of 8-alkoxy-9h-isothiazolo[5,4-b]quinoline-3,4-diones
WO2007119116A3 (en) Improved synthesis and preparations of duloxetine salts
WO2009065872A3 (en) Processes for the synthesis of varenicline l-tartrate
IL175253A0 (en) A process for preparing pyrrole derivatives
UA106195C2 (en) Process for the synthesis of agomelatine
WO2010113182A8 (en) Intermediates in the preparation of 1,4-diphenyl azetidinone
WO2011038169A3 (en) Oxalamide derivative as umami flavouring agent
WO2007016029A3 (en) Diazepinoquinolines, synthesis thereof, and intermediates thereto
WO2009140205A3 (en) Therapeutic substituted cyclopentanes

Legal Events

Date Code Title Description
121 Ep: the epo has been informed by wipo that ep was designated in this application

Ref document number: 08764551

Country of ref document: EP

Kind code of ref document: A1

ENP Entry into the national phase

Ref document number: 2009515279

Country of ref document: JP

Kind code of ref document: A

NENP Non-entry into the national phase

Ref country code: DE

122 Ep: pct application non-entry in european phase

Ref document number: 08764551

Country of ref document: EP

Kind code of ref document: A1