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WO2008143015A1 - コハク酸およびコハク酸アンモニウム溶液の製造方法 - Google Patents

コハク酸およびコハク酸アンモニウム溶液の製造方法 Download PDF

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Publication number
WO2008143015A1
WO2008143015A1 PCT/JP2008/058569 JP2008058569W WO2008143015A1 WO 2008143015 A1 WO2008143015 A1 WO 2008143015A1 JP 2008058569 W JP2008058569 W JP 2008058569W WO 2008143015 A1 WO2008143015 A1 WO 2008143015A1
Authority
WO
WIPO (PCT)
Prior art keywords
production
succinate
solution
succinic acid
calcium
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Ceased
Application number
PCT/JP2008/058569
Other languages
English (en)
French (fr)
Inventor
Kiyohiko Nishi
Hiroshi Kaneko
Hirofumi Tasaki
Masaki Koga
Testuo Tanegawa
Seisaku Furuya
Kenji Fujiwara
Takeru Satou
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Ajinomoto Co Inc
Original Assignee
Ajinomoto Co Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Ajinomoto Co Inc filed Critical Ajinomoto Co Inc
Priority to EP08752455.9A priority Critical patent/EP2157185B1/en
Priority to JP2009515148A priority patent/JP5333213B2/ja
Publication of WO2008143015A1 publication Critical patent/WO2008143015A1/ja
Priority to US12/620,747 priority patent/US8034975B2/en
Anticipated expiration legal-status Critical
Ceased legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P7/00—Preparation of oxygen-containing organic compounds
    • C12P7/40—Preparation of oxygen-containing organic compounds containing a carboxyl group including Peroxycarboxylic acids
    • C12P7/44—Polycarboxylic acids
    • C12P7/46—Dicarboxylic acids having four or less carbon atoms, e.g. fumaric acid, maleic acid
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C51/00—Preparation of carboxylic acids or their salts, halides or anhydrides
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C51/00—Preparation of carboxylic acids or their salts, halides or anhydrides
    • C07C51/41—Preparation of salts of carboxylic acids
    • C07C51/412—Preparation of salts of carboxylic acids by conversion of the acids, their salts, esters or anhydrides with the same carboxylic acid part
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C51/00—Preparation of carboxylic acids or their salts, halides or anhydrides
    • C07C51/42—Separation; Purification; Stabilisation; Use of additives
    • C07C51/43—Separation; Purification; Stabilisation; Use of additives by change of the physical state, e.g. crystallisation

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  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Health & Medical Sciences (AREA)
  • Microbiology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Biochemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Biotechnology (AREA)
  • Crystallography & Structural Chemistry (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)

Abstract

本発明は、発酵由来のコハク酸製造にあたり、複雑な工程を経ず、副生物が全てコハク酸製造に再利用可能なコハク酸アンモニウム溶液を効率よく製造するものであり、発酵由来のコハク酸アンモニウムを製造するに際し、 　（１）コハク酸カルシウム・３水和物を微生物により製造する晶析発酵工程、 　（２）コハク酸カルシウム・３水和物をコハク酸カルシウム・１水和物に転移晶析する転移工程 　（３）コハク酸カルシウム・１水和物を分離する結晶分離工程 　（４）分離したコハク酸カルシウム・１水和物をコハク酸アンモニウム溶液にする塩置換工程 　（５）コハク酸アンモニウム溶液より炭酸カルシウム沈殿を除去する固液分離工程　からなる。  
PCT/JP2008/058569 2007-05-18 2008-05-08 コハク酸およびコハク酸アンモニウム溶液の製造方法 Ceased WO2008143015A1 (ja)

Priority Applications (3)

Application Number Priority Date Filing Date Title
EP08752455.9A EP2157185B1 (en) 2007-05-18 2008-05-08 Process for production of succinic acid, and process for production of ammonium succinate solution
JP2009515148A JP5333213B2 (ja) 2007-05-18 2008-05-08 コハク酸およびコハク酸アンモニウム溶液の製造方法
US12/620,747 US8034975B2 (en) 2007-05-18 2009-11-18 Method of manufacturing succinic acid and ammonium succinate solutions

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
JP2007-132917 2007-05-18
JP2007132917 2007-05-18

Related Child Applications (1)

Application Number Title Priority Date Filing Date
US12/620,747 Continuation US8034975B2 (en) 2007-05-18 2009-11-18 Method of manufacturing succinic acid and ammonium succinate solutions

Publications (1)

Publication Number Publication Date
WO2008143015A1 true WO2008143015A1 (ja) 2008-11-27

Family

ID=40031727

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/JP2008/058569 Ceased WO2008143015A1 (ja) 2007-05-18 2008-05-08 コハク酸およびコハク酸アンモニウム溶液の製造方法

Country Status (4)

Country Link
US (1) US8034975B2 (ja)
EP (1) EP2157185B1 (ja)
JP (1) JP5333213B2 (ja)
WO (1) WO2008143015A1 (ja)

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2010063762A3 (en) * 2008-12-02 2010-08-05 Purac Biochem Bv Process for the preparation of a monovalent succinate salt
CN103827308A (zh) * 2011-07-21 2014-05-28 阿彻丹尼尔斯米德兰德公司 通过发酵制备c4二酸的铵盐的方法及制备其c4衍生物的综合方法

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
NZ589053A (en) * 2006-10-27 2012-03-30 Signal Pharm Llc Process of preparing 4-[9-(tetrahydro-furan-3-yl)-8-(2,4,6-trifluoro-phenylamino)-9h-purin-2-ylamino]-cyclohexan-1-ol compounds
ES2432642T3 (es) 2010-02-12 2013-12-04 Purac Biochem Bv Proceso de producción de ácido succínico
CN102918017B (zh) 2010-03-26 2014-12-17 生物琥珀酸有限公司 从含有琥珀酸二铵、琥珀酸一铵和/或琥珀酸的发酵液制备琥珀酸一铵的方法及琥珀酸一铵到琥珀酸的转化
WO2011123268A1 (en) 2010-04-01 2011-10-06 Bioamber S.A.S. Processes for producing succinic acid from fermentation broths containing diammonium succinate
KR20130020779A (ko) 2010-04-01 2013-02-28 바이오엠버 인터내셔널 에스.에이.알.엘. 숙신산염으로부터 테트라하이드로퓨란, 감마-부티로락톤 및/또는 부탄디올의 제조방법
US8410291B2 (en) 2010-04-01 2013-04-02 BioAmber International S.á.r.l. Processes for the production of hydrogenated products
US8399687B2 (en) 2010-04-01 2013-03-19 Bioamber International S.A.R.L. Processes for the production of hydrogenated products
CA2807102C (en) * 2010-07-31 2018-08-21 Myriant Corporation Improved fermentation process for the production of organic acids
US20120259138A1 (en) * 2011-04-05 2012-10-11 BioAmber International S.à.r.I. Methods and systems of producing dicarboxylic acids
WO2019234092A1 (de) 2018-06-07 2019-12-12 Covestro Deutschland Ag Verfahren zur herstellung von aminobenzoesäure oder eines aminobenzosäure-folgeprodukts

Citations (8)

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Publication number Priority date Publication date Assignee Title
JPS62294090A (ja) 1986-06-11 1987-12-21 シ−・ピ−・シ−・インタ−ナシヨナル・インコ−ポレイテツド 嫌気性発酵によりコハク酸を製造する方法
JPH02283289A (ja) 1989-03-17 1990-11-20 Michigan Biotechnol Inst コハク酸の製造及び精製方法
JPH0330685A (ja) 1989-06-28 1991-02-08 Michigan Biotechnol Inst コハク酸の発酵および精製法
JP2001514900A (ja) 1997-08-18 2001-09-18 アプライド カーボケミカルズ コハク酸の製造方法および精製方法
JP2004196768A (ja) 2002-05-10 2004-07-15 Mitsubishi Chemicals Corp 有機酸の製造方法及びアンモニウム塩の分解方法、並びに有機酸及びポリマー
WO2005026349A1 (ja) 2003-09-17 2005-03-24 Mitsubishi Chemical Corporation 非アミノ有機酸の製造方法
JP2005139137A (ja) 2003-11-07 2005-06-02 Ajinomoto Co Inc 有機酸の製造方法
JP2005295998A (ja) 2003-11-07 2005-10-27 Mitsubishi Chemicals Corp 有機酸アンモニウム溶液の製造方法

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPH1192502A (ja) 1997-09-19 1999-04-06 Bio Polymer Reserch:Kk 酸素富化条件下でのバクテリアセルロースの製造方法
EP1482055B1 (en) * 2003-05-26 2006-03-01 Ajinomoto Co., Inc. Method for producing cadaverine dicarboxylate and its use for the production of nylon
CN100575496C (zh) 2003-08-28 2009-12-30 三菱化学株式会社 产生琥珀酸的方法
EP1669459B1 (en) * 2003-09-30 2014-10-22 Ajinomoto Co., Inc. Method of purifying succinic acid from fermentation liquid
WO2005045049A1 (ja) * 2003-11-07 2005-05-19 Mitsubishi Chemical Corporation 有機酸アンモニウム溶液の製造方法

Patent Citations (8)

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JPS62294090A (ja) 1986-06-11 1987-12-21 シ−・ピ−・シ−・インタ−ナシヨナル・インコ−ポレイテツド 嫌気性発酵によりコハク酸を製造する方法
JPH02283289A (ja) 1989-03-17 1990-11-20 Michigan Biotechnol Inst コハク酸の製造及び精製方法
JPH0330685A (ja) 1989-06-28 1991-02-08 Michigan Biotechnol Inst コハク酸の発酵および精製法
JP2001514900A (ja) 1997-08-18 2001-09-18 アプライド カーボケミカルズ コハク酸の製造方法および精製方法
JP2004196768A (ja) 2002-05-10 2004-07-15 Mitsubishi Chemicals Corp 有機酸の製造方法及びアンモニウム塩の分解方法、並びに有機酸及びポリマー
WO2005026349A1 (ja) 2003-09-17 2005-03-24 Mitsubishi Chemical Corporation 非アミノ有機酸の製造方法
JP2005139137A (ja) 2003-11-07 2005-06-02 Ajinomoto Co Inc 有機酸の製造方法
JP2005295998A (ja) 2003-11-07 2005-10-27 Mitsubishi Chemicals Corp 有機酸アンモニウム溶液の製造方法

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"Sekko Sekkai Handbook (Gypsum Line Handbook)", 1972, GIHODO SHUPPAN, pages: L26 - 144
LIELBL, W. ET AL., INTERNATIONAL JOURNAL OF SYSTEMATIC BACTERIOLOGY, vol. 41, 1991, pages 255 - 260

Cited By (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2010063762A3 (en) * 2008-12-02 2010-08-05 Purac Biochem Bv Process for the preparation of a monovalent succinate salt
JP2012510451A (ja) * 2008-12-02 2012-05-10 ピュラック バイオケム ビー．ブイ． 一価のコハク酸塩の製造方法
US8865438B2 (en) 2008-12-02 2014-10-21 Purac Biochem B.V. Process for the preparation of a monovalent succinate salt
AU2009324161B2 (en) * 2008-12-02 2016-04-14 Purac Biochem Bv Process for the preparation of a monovalent succinate salt
CN102612563B (zh) * 2008-12-02 2016-09-14 普拉克生化公司 一价琥珀酸盐的制备方法
KR101767034B1 (ko) * 2008-12-02 2017-08-10 푸락 바이오켐 비.브이. １가 숙신산 염의 제조방법
CN103827308A (zh) * 2011-07-21 2014-05-28 阿彻丹尼尔斯米德兰德公司 通过发酵制备c4二酸的铵盐的方法及制备其c4衍生物的综合方法
CN103827308B (zh) * 2011-07-21 2016-08-24 阿彻丹尼尔斯米德兰德公司 通过发酵制备c4二酸的铵盐的方法及制备其c4衍生物的综合方法

Also Published As

Publication number Publication date
EP2157185B1 (en) 2014-05-14
US8034975B2 (en) 2011-10-11
US20100094051A1 (en) 2010-04-15
JPWO2008143015A1 (ja) 2010-08-05
JP5333213B2 (ja) 2013-11-06
EP2157185A1 (en) 2010-02-24
EP2157185A4 (en) 2011-06-08

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