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WO2008142129A3 - Partially degradable scaffolds for biomedical applications - Google Patents

Partially degradable scaffolds for biomedical applications Download PDF

Info

Publication number
WO2008142129A3
WO2008142129A3 PCT/EP2008/056299 EP2008056299W WO2008142129A3 WO 2008142129 A3 WO2008142129 A3 WO 2008142129A3 EP 2008056299 W EP2008056299 W EP 2008056299W WO 2008142129 A3 WO2008142129 A3 WO 2008142129A3
Authority
WO
WIPO (PCT)
Prior art keywords
material layer
bioactive material
partially degradable
biomedical applications
degradable scaffolds
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Ceased
Application number
PCT/EP2008/056299
Other languages
French (fr)
Other versions
WO2008142129A2 (en
Inventor
Soheil Asgari
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Cinvention AG
Original Assignee
Cinvention AG
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Cinvention AG filed Critical Cinvention AG
Priority to CA002687637A priority Critical patent/CA2687637A1/en
Priority to AU2008252907A priority patent/AU2008252907A1/en
Priority to EP08759900A priority patent/EP2146756A2/en
Publication of WO2008142129A2 publication Critical patent/WO2008142129A2/en
Publication of WO2008142129A3 publication Critical patent/WO2008142129A3/en
Anticipated expiration legal-status Critical
Ceased legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/28—Materials for coating prostheses
    • A61L27/30—Inorganic materials
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/50—Materials characterised by their function or physical properties, e.g. injectable or lubricating compositions, shape-memory materials, surface modified materials
    • A61L27/58—Materials at least partially resorbable by the body
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
    • C12M25/00—Means for supporting, enclosing or fixing the microorganisms, e.g. immunocoatings
    • C12M25/14—Scaffolds; Matrices

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Transplantation (AREA)
  • Epidemiology (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Dermatology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Organic Chemistry (AREA)
  • Zoology (AREA)
  • Oral & Maxillofacial Surgery (AREA)
  • Wood Science & Technology (AREA)
  • Biotechnology (AREA)
  • Microbiology (AREA)
  • Sustainable Development (AREA)
  • Biomedical Technology (AREA)
  • Inorganic Chemistry (AREA)
  • Biochemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • Genetics & Genomics (AREA)
  • Immunology (AREA)
  • Materials For Medical Uses (AREA)
  • Prostheses (AREA)

Abstract

The present invention is directed to a scaffold for tissue engineering, comprising a support structure having an outer surface, at least a part of the outer surface being covered by a bioactive material layer that allows cell attachment, wherein the bioactive material layer is at least partially degradable in an environment of use, to allow a detachment of the cells from the support structure by degradation of the bioactive material layer. The invention is further directed to the use of an at least partially degradable bioactive material layer on a scaffold for tissue engineering, for allowing detachment of the cells or grown tissue by degradation of the bioactive material layer.
PCT/EP2008/056299 2007-05-22 2008-05-21 Partially degradable scaffolds for biomedical applications Ceased WO2008142129A2 (en)

Priority Applications (3)

Application Number Priority Date Filing Date Title
CA002687637A CA2687637A1 (en) 2007-05-22 2008-05-21 Partially degradable scaffolds for biomedical applications
AU2008252907A AU2008252907A1 (en) 2007-05-22 2008-05-21 Partially degradable scaffolds for biomedical applications
EP08759900A EP2146756A2 (en) 2007-05-22 2008-05-21 Partially degradable scaffolds for biomedical applications

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US93960707P 2007-05-22 2007-05-22
US60/939,607 2007-05-22

Publications (2)

Publication Number Publication Date
WO2008142129A2 WO2008142129A2 (en) 2008-11-27
WO2008142129A3 true WO2008142129A3 (en) 2009-02-05

Family

ID=39855181

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/EP2008/056299 Ceased WO2008142129A2 (en) 2007-05-22 2008-05-21 Partially degradable scaffolds for biomedical applications

Country Status (4)

Country Link
EP (1) EP2146756A2 (en)
AU (1) AU2008252907A1 (en)
CA (1) CA2687637A1 (en)
WO (1) WO2008142129A2 (en)

Families Citing this family (18)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US8557288B2 (en) 2008-08-15 2013-10-15 Washington University Hydrogel microparticle formation in aqueous solvent for biomedical applications
US10240419B2 (en) 2009-12-08 2019-03-26 Baker Hughes, A Ge Company, Llc Downhole flow inhibition tool and method of unplugging a seat
US9707739B2 (en) 2011-07-22 2017-07-18 Baker Hughes Incorporated Intermetallic metallic composite, method of manufacture thereof and articles comprising the same
US9033055B2 (en) 2011-08-17 2015-05-19 Baker Hughes Incorporated Selectively degradable passage restriction and method
US9010416B2 (en) 2012-01-25 2015-04-21 Baker Hughes Incorporated Tubular anchoring system and a seat for use in the same
US10553875B2 (en) 2013-04-16 2020-02-04 California Institute Of Technology Use and fabrication of microscaffolds and nanoscaffolds
WO2014172495A2 (en) * 2013-04-16 2014-10-23 California Institute Of Technology Design, use and fabrication of microscaffolds and nanoscaffolds
US9816339B2 (en) 2013-09-03 2017-11-14 Baker Hughes, A Ge Company, Llc Plug reception assembly and method of reducing restriction in a borehole
CN104414772A (en) * 2013-09-06 2015-03-18 山东百多安医疗器械有限公司 In-vivo degradable and absorbable artificial medical tissue repairing film
US10689740B2 (en) 2014-04-18 2020-06-23 Terves, LLCq Galvanically-active in situ formed particles for controlled rate dissolving tools
WO2015127174A1 (en) 2014-02-21 2015-08-27 Terves, Inc. Fluid activated disintegrating metal system
US11167343B2 (en) 2014-02-21 2021-11-09 Terves, Llc Galvanically-active in situ formed particles for controlled rate dissolving tools
GB201410506D0 (en) * 2014-06-12 2014-07-30 Cell Therapy Ltd Hybrid composition
US10378303B2 (en) 2015-03-05 2019-08-13 Baker Hughes, A Ge Company, Llc Downhole tool and method of forming the same
CA3012511A1 (en) 2017-07-27 2019-01-27 Terves Inc. Degradable metal matrix composite
CN109465170A (en) * 2018-09-26 2019-03-15 湖北大学 A coating for fast photohealing based on near-infrared laser response and its preparation method and application
CN113913805B (en) * 2021-10-20 2023-08-22 中南大学湘雅医院 A kind of cold spray modified layer and its application
WO2025117862A1 (en) * 2023-12-01 2025-06-05 Allumin8, Inc. Scaffolds based on continuous folded sheets

Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP1027897A1 (en) * 1999-02-10 2000-08-16 Isotis B.V. Cartillage tissue engineering
WO2001034060A1 (en) * 1999-11-12 2001-05-17 The Trustees Of The University Of Pennsylvania Bioactive, degradable composite for tissue engineering
US20040098108A1 (en) * 2002-11-13 2004-05-20 Biotronik Gmbh & Co. Kg Endoprosthesis

Patent Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP1027897A1 (en) * 1999-02-10 2000-08-16 Isotis B.V. Cartillage tissue engineering
WO2001034060A1 (en) * 1999-11-12 2001-05-17 The Trustees Of The University Of Pennsylvania Bioactive, degradable composite for tissue engineering
US20040098108A1 (en) * 2002-11-13 2004-05-20 Biotronik Gmbh & Co. Kg Endoprosthesis

Also Published As

Publication number Publication date
AU2008252907A1 (en) 2008-11-27
WO2008142129A2 (en) 2008-11-27
EP2146756A2 (en) 2010-01-27
CA2687637A1 (en) 2008-11-27

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