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WO2008039052A3 - Proceso para estabilización de famotidina - Google Patents

Proceso para estabilización de famotidina Download PDF

Info

Publication number
WO2008039052A3
WO2008039052A3 PCT/MX2007/000108 MX2007000108W WO2008039052A3 WO 2008039052 A3 WO2008039052 A3 WO 2008039052A3 MX 2007000108 W MX2007000108 W MX 2007000108W WO 2008039052 A3 WO2008039052 A3 WO 2008039052A3
Authority
WO
WIPO (PCT)
Prior art keywords
famotidine
composition
wax
present
stabilizing
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Ceased
Application number
PCT/MX2007/000108
Other languages
English (en)
French (fr)
Other versions
WO2008039052A2 (es
WO2008039052A8 (es
Inventor
Abdala Leopoldo De Je Espinoza
Armanta Maria Elena Garcia
Ochoa Victor Guillermo Alvarez
Murillo Josefina Santos
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Individual
Original Assignee
Individual
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Individual filed Critical Individual
Priority to EP07834489A priority Critical patent/EP2085079A2/en
Priority to BRPI0717425-0A priority patent/BRPI0717425A2/pt
Publication of WO2008039052A2 publication Critical patent/WO2008039052A2/es
Publication of WO2008039052A3 publication Critical patent/WO2008039052A3/es
Anticipated expiration legal-status Critical
Publication of WO2008039052A8 publication Critical patent/WO2008039052A8/es
Ceased legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0087—Galenical forms not covered by A61K9/02 - A61K9/7023
    • A61K9/0095—Drinks; Beverages; Syrups; Compositions for reconstitution thereof, e.g. powders or tablets to be dispersed in a glass of water; Veterinary drenches
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
    • A61K9/5005—Wall or coating material
    • A61K9/5015—Organic compounds, e.g. fats, sugars
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants

Landscapes

  • Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Manufacturing Of Micro-Capsules (AREA)

Abstract

La presente invención está relacionada con la industria farmacéutica, y más específicamente con la industria farmacéutica de la manufactura de productos a partir de la famotidina. La presente invención describe un método para estabilizar en pH alcalino a un inhibidor de receptores de H2 tal como lo es la Famotidina mediante un proceso de microencapsulación utilizando como materiales formadores de la película productos en cera o de naturaleza polimérica, tal como lo es la cera microcristalina, cera montánica, cera ozoquerita, chitosan o alginato de sodio. Las ventajas de la presente invención con respecto de los procedimientos del estado de la técnica es el de hacer posible con su aplicación de una composición de famotidina que resista más el medio de la composición en la que se encuentra y los efectos que pudiera tener la composición en el tracto digestivo. Sobre todo cuando esta sustancia se incluye en una composición conteniendo antiácido alcalino.
PCT/MX2007/000108 2006-09-25 2007-09-24 Proceso para estabilización de famotidina Ceased WO2008039052A2 (es)

Priority Applications (2)

Application Number Priority Date Filing Date Title
EP07834489A EP2085079A2 (en) 2006-09-25 2007-09-24 Process for stabilizing famotidine
BRPI0717425-0A BRPI0717425A2 (pt) 2006-09-25 2007-09-24 Processo para estabilização de famotidina

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
MXPA/A/2006/010972 2006-09-25
MXPA06010972A MXPA06010972A (es) 2006-09-25 2006-09-25 Proceso para estabilizacion de famotidina.

Publications (3)

Publication Number Publication Date
WO2008039052A2 WO2008039052A2 (es) 2008-04-03
WO2008039052A3 true WO2008039052A3 (es) 2008-06-19
WO2008039052A8 WO2008039052A8 (es) 2009-05-07

Family

ID=39230698

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/MX2007/000108 Ceased WO2008039052A2 (es) 2006-09-25 2007-09-24 Proceso para estabilización de famotidina

Country Status (8)

Country Link
EP (1) EP2085079A2 (es)
AR (1) AR062987A1 (es)
BR (1) BRPI0717425A2 (es)
CL (1) CL2007002760A1 (es)
CO (1) CO6160290A2 (es)
CR (1) CR10685A (es)
MX (1) MXPA06010972A (es)
WO (1) WO2008039052A2 (es)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
MX351059B (es) * 2012-08-17 2017-09-29 Laboratorios Senosiain S A De C V Star Composicion farmaceutica oral en forma de microesferas y proceso de elaboracion.
WO2018083583A1 (en) * 2016-11-01 2018-05-11 Johnson & Johnson Consumer Inc. Liquid oral pharmaceutical dosage form comprising an histamine h2-receptor antagonist and an antacid
AU2018343214B2 (en) * 2017-09-29 2023-10-05 Kenvue Brands Llc Solid simethicone particles and dosage form thereof
CN112020350A (zh) 2018-04-27 2020-12-01 强生消费者公司 液体口服药物剂型
AU2019360443B2 (en) 2018-10-18 2024-10-31 Kenvue Brands Llc Novel dosage form
US20220331294A1 (en) * 2019-09-27 2022-10-20 Johnson & Johnson Consumer Inc. Gel-chewable dosage form

Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20020147204A1 (en) * 1997-10-27 2002-10-10 Sumitomo Pharmaceuticals Company, Limited Amide derivative
US20050053655A1 (en) * 2003-09-05 2005-03-10 Pharmaceutical Industry Technology And Development Center Rapid disintegrating tablets (RDTs) for pharmaceutical use and method for preparing the same

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20020147204A1 (en) * 1997-10-27 2002-10-10 Sumitomo Pharmaceuticals Company, Limited Amide derivative
US20050053655A1 (en) * 2003-09-05 2005-03-10 Pharmaceutical Industry Technology And Development Center Rapid disintegrating tablets (RDTs) for pharmaceutical use and method for preparing the same

Non-Patent Citations (2)

* Cited by examiner, † Cited by third party
Title
CHIAPPETTA D.A.: "Microencapsulacion of medicamentos", 14 April 2004 (2004-04-14), XP008104739, Retrieved from the Internet <URL:http://www.ffyb.uba.ar/farmacotecnia%20I/Microencapsulacion.htm> *
MARTIN-BANDERAS L. ET AL.: "Microcapsulas of famotidina of liberacion programada para administraction oral", CIENC. TECNOL. PHARM., vol. 13, no. 3, 2003, pages 87 - 98, XP008104756 *

Also Published As

Publication number Publication date
CO6160290A2 (es) 2010-05-20
WO2008039052A2 (es) 2008-04-03
MXPA06010972A (es) 2009-04-17
EP2085079A2 (en) 2009-08-05
AR062987A1 (es) 2008-12-17
CR10685A (es) 2009-05-22
WO2008039052A8 (es) 2009-05-07
CL2007002760A1 (es) 2008-04-25
BRPI0717425A2 (pt) 2013-11-12

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