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WO2008038305A3 - Therapeutical formulation comprising a thiazolidinedione and a nitric oxide scavenger. - Google Patents

Therapeutical formulation comprising a thiazolidinedione and a nitric oxide scavenger. Download PDF

Info

Publication number
WO2008038305A3
WO2008038305A3 PCT/IN2007/000437 IN2007000437W WO2008038305A3 WO 2008038305 A3 WO2008038305 A3 WO 2008038305A3 IN 2007000437 W IN2007000437 W IN 2007000437W WO 2008038305 A3 WO2008038305 A3 WO 2008038305A3
Authority
WO
WIPO (PCT)
Prior art keywords
thiazolidinedione
nitric oxide
oxide scavenger
formulation
therapeutical
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Ceased
Application number
PCT/IN2007/000437
Other languages
French (fr)
Other versions
WO2008038305A2 (en
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Individual
Original Assignee
Individual
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Individual filed Critical Individual
Publication of WO2008038305A2 publication Critical patent/WO2008038305A2/en
Publication of WO2008038305A3 publication Critical patent/WO2008038305A3/en
Anticipated expiration legal-status Critical
Ceased legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/325—Carbamic acids; Thiocarbamic acids; Anhydrides or salts thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/425—Thiazoles
    • A61K31/427—Thiazoles not condensed and containing further heterocyclic rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/555—Heterocyclic compounds containing heavy metals, e.g. hemin, hematin, melarsoprol
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Epidemiology (AREA)
  • Diabetes (AREA)
  • Endocrinology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Hematology (AREA)
  • Obesity (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Emergency Medicine (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Thiazole And Isothizaole Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)

Abstract

A therapeutic formulation comprising of Thiazolidinediones as active agents namely, Pioglitazone and Rosiglitazone, characterized in that said Thiazolidinediones are combined or complexated with NO Scavenger to prevent Diabetic Complications arising out of Nitrosative stress.
PCT/IN2007/000437 2006-09-26 2007-09-26 Therapeutical formulation comprising a thiazolidinedione and a nitric oxide scavenger. Ceased WO2008038305A2 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
IN1762/CHE/2006 2006-09-26
IN1762CH2006 2006-09-26

Publications (2)

Publication Number Publication Date
WO2008038305A2 WO2008038305A2 (en) 2008-04-03
WO2008038305A3 true WO2008038305A3 (en) 2008-05-15

Family

ID=39230689

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/IN2007/000437 Ceased WO2008038305A2 (en) 2006-09-26 2007-09-26 Therapeutical formulation comprising a thiazolidinedione and a nitric oxide scavenger.

Country Status (1)

Country Link
WO (1) WO2008038305A2 (en)

Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20020049190A1 (en) * 1999-03-19 2002-04-25 Bridger Gary J. Pharmaceutical compositions comprising metal complexes
US20030087840A1 (en) * 1998-05-19 2003-05-08 Medinox, Inc. Conjugates of dithiocarbamates with pharmacologically active agents and uses therefor
US20030181495A1 (en) * 1998-06-23 2003-09-25 Medinox, Inc. Therapeutic methods employing disulfide derivatives of dithiocarbamates and compositions useful therefor

Patent Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20030087840A1 (en) * 1998-05-19 2003-05-08 Medinox, Inc. Conjugates of dithiocarbamates with pharmacologically active agents and uses therefor
US20030181495A1 (en) * 1998-06-23 2003-09-25 Medinox, Inc. Therapeutic methods employing disulfide derivatives of dithiocarbamates and compositions useful therefor
US20020049190A1 (en) * 1999-03-19 2002-04-25 Bridger Gary J. Pharmaceutical compositions comprising metal complexes

Also Published As

Publication number Publication date
WO2008038305A2 (en) 2008-04-03

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