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WO2008031257A1 - A percussion-controlling device of gene gun - Google Patents

A percussion-controlling device of gene gun Download PDF

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Publication number
WO2008031257A1
WO2008031257A1 PCT/CN2006/002129 CN2006002129W WO2008031257A1 WO 2008031257 A1 WO2008031257 A1 WO 2008031257A1 CN 2006002129 W CN2006002129 W CN 2006002129W WO 2008031257 A1 WO2008031257 A1 WO 2008031257A1
Authority
WO
WIPO (PCT)
Prior art keywords
firing
valve shaft
tube portion
gene gun
firing tube
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Ceased
Application number
PCT/CN2006/002129
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English (en)
French (fr)
Inventor
Hai-Lung Huang
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Individual
Original Assignee
Individual
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Filing date
Publication date
Application filed by Individual filed Critical Individual
Priority to PCT/CN2006/002129 priority Critical patent/WO2008031257A1/zh
Publication of WO2008031257A1 publication Critical patent/WO2008031257A1/zh
Anticipated expiration legal-status Critical
Ceased legal-status Critical Current

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
    • C12M35/00—Means for application of stress for stimulating the growth of microorganisms or the generation of fermentation or metabolic products; Means for electroporation or cell fusion
    • C12M35/04—Mechanical means, e.g. sonic waves, stretching forces, pressure or shear stimuli
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies

Definitions

  • the present invention relates to a gene gun, and more particularly to the structural design proposed for the firing control device in the gene gun. Background technique
  • a gene gun is a tool used for gene transfer and other purposes. It mainly uses high-pressure gas (helium, nitrogen, etc.) to attach DNA or vaccine to metal particles (such as high-density metal particles such as tungsten and gold). Pushed into the deep layers of plants and animals to overcome the biological limitations of the cell wall, it is widely used in animal and plant gene transfer, gene therapy, vaccine research and so on.
  • high-pressure gas helium, nitrogen, etc.
  • the design of the aforementioned gene gun mainly includes a gas pipeline externally connected to a high-pressure gas source, and a gene gun body.
  • the gas pipeline is provided with a control group, and the gene gun body is provided with a grip, and a starter device is connected to the control group.
  • the gene gun body is provided with a device such as a sprayer and a feeding mechanism, and a vaccine, DNA, or the like is input by the feeding mechanism, thereby controlling the input of the high-pressure gas, and the vaccine or DNA is directed to the target via the sprayer. Things.
  • the aforementioned gene gun design is an apparatus for transferring a vaccine into an animal or plant.
  • the firing control group of the gene gun rapidly injects the vaccine into the plant and animal cells at each firing. Immediately after the stop, the appropriate follow-up thrust is not provided, making the vaccine difficult to reach the intended location of the target, thus affecting the effectiveness of the vaccine. Summary of the invention
  • a primary object of the present invention is to provide a firing control device for a gene gun that further provides a subsequent thrust when the gene gun is fired, so that the vaccine can be effectively controlled to be launched at a predetermined position of the target.
  • the firing control device for a gene gun of the present invention comprises: a firing control group and a trigger unit disposed in a gene gun body, wherein the firing control group includes a valve shaft and an action a plate, a spring and an adjusting block, the valve shaft is air-tightly arranged in the firing tube portion of the gun body, the valve shaft has a valve block at the front end thereof, and the valve port of the firing tube portion is controlled to open and close, and the action plate is pivoted In the firing tube portion, the upper end is connected to the valve shaft, and the lower end extends beyond the firing tube portion to connect the firing member of the trigger unit to the torsion spring.
  • the adjusting block has a screwing portion, and the adjustable position is screwed to the firing tube portion.
  • the spring is disposed in the firing tube portion and abuts between the rear end of the valve shaft and the adjusting block; or the firing control group includes a valve shaft and a spring, and the spring is sleeved on the valve shaft and abuts
  • the firing portion is connected between the pipe portion and the valve shaft, and the rear end of the valve shaft is connected to the firing member of the trigger unit which is subjected to the torsion spring.
  • the achievable effect of the present invention is: when the firing control device is applied to the gene gun, in addition to the firing control group, the introduction of the high pressure gas can be controlled, and is introduced into the barrel of the front end of the gun body.
  • the vaccine provides power to the target object.
  • the firing control group of the present invention is further abutted against the upper end of the plate through the spring of the valve shaft, and is offset from the lower end of the action plate by a trigger unit acting on the torsion spring, or
  • the spring valve shaft directly abuts against the trigger unit that is subjected to the torsion spring, and the force part of the valve shaft is offset, delaying the valve port time of the front end of the valve shaft to close the firing tube portion, thereby prolonging the action time of the high pressure gas push vaccine.
  • the vaccine can be made deeper to the intended location of the target.
  • Figure 1 is a schematic plan view showing the first preferred embodiment of the gene gun firing control device of the present invention applied to a gene gun.
  • FIG. 2 to 6 are schematic views showing the operation of the first preferred embodiment of the firing control device shown in Fig. 1 applied to a gene gun.
  • Fig. 7 is a schematic view showing the operation of adjusting the elastic force of the first preferred embodiment of the gene gun firing control device shown in Fig. 1.
  • Fig. 8 is a schematic plan view showing the first preferred embodiment of the gene gun firing control device of the present invention applied to another type of gene gun.
  • FIG. 9 to 11 are schematic views showing the operation of the first preferred embodiment of the firing control device shown in FIG. 8 applied to another type of gene gun.
  • Figure 12 is a schematic plan view showing the application of the second preferred embodiment of the gene gun firing control device of the present invention to a gene gun.
  • FIG. 13 to 15 are views showing the operation of the second preferred embodiment of the firing control device shown in Fig. 12 applied to a gene gun.
  • a schematic diagram of a second gene gun which can be seen in the figure, includes a gun body 10, a barrel 40, and a firing control device of the present invention.
  • the firing control device includes a trigger unit 30 and a firing control group. 20, where:
  • the upper portion of the gun body 10 has a lateral firing tube portion 11 and a gun handle on the rear side of the firing tube portion 11.
  • the firing tube portion 11 is internally provided with an assembly hole 12 at the front end and an air chamber. 13 is located behind the assembly hole 12, and an action chamber 14 is located behind the air chamber 13.
  • the assembly hole 12 and the air chamber 13 are connected with a valve port 16 having a slightly smaller aperture.
  • the valve port 16 is adjacent to one end of the air chamber 13.
  • the air chamber 13 and the action chamber 14 are connected to a middle hole having a slightly smaller aperture, and a relay block 15 is disposed between the air chamber 13 and the action chamber 14.
  • the relay block 15 is connected to the air chamber 13 and the operating chamber 14, and the firing tube portion 11 is provided with an air inlet hole 18 extending from the outside into the air chamber 13 for externally connecting a high-pressure air source.
  • the firing tube portion 11 is further provided with a through hole 17 extending upward from the bottom of the firing tube portion 11 to the front portion of the operating chamber 14.
  • the rear end of the firing tube portion 11 is further provided with a screw hole 19 communicating axially from the outside to the operating chamber 14.
  • the air inlet hole 18 provided in the gun body 10 is designed as shown in FIG. 1, FIG. 8, etc., wherein, in the embodiment shown in FIG. 1, the air inlet hole 18 is taken from the side of the firing tube portion 11. Radially penetrates into the air chamber 13, as shown in the embodiment of Fig. 8, the air inlet hole 18 extends forward from the rear end of the firing tube portion 11 and penetrates downward to the air chamber 13.
  • the rear end of the barrel 40 has a connecting portion 43 for assembling into the mounting hole 12 at the front end of the gun body 10.
  • the barrel 40 has an axially extending tube hole 41, and the middle portion of the tube hole 41 is small.
  • the hole section 411, the front and the rear sections respectively form a tapered expansion section 412, 413 which gradually increases in diameter toward the outside, and forms a Venturi tubular.
  • the middle section of the barrel 40 is further provided with a small-aperture vaccine inlet 42 extending from the outside. Up to the small hole section 411, the vaccine inlet 42 can also be provided with a connecting member 44 for externally connecting the gene source.
  • the trigger unit 30 of the present invention comprises a gusset 31, a firing member 32 and two torsion springs 33, 34.
  • the gusset 31 is assembled to the bottom of the gun body 10 by a pivotal engagement torque spring 33 at its upper end.
  • the outer side of the bottom end of the gun body 10 is disposed in the gun body 10 with a lower end of the firing member 32, and the upper end portion of the firing member 32 extends below the through hole 17 of the firing portion 11.
  • the latching portion 311 and the passive portion 321 are respectively disposed at adjacent ends of the gusset 31 and the firing member 32.
  • the firing control group 20 of the present invention is mounted in the firing tube portion 11 of the gun body 10, and includes a valve shaft 21, an action plate 22, a spring 23 and an adjusting block 24, wherein - the valve shaft 21 is in the middle portion
  • the airtightly movable group is disposed in the middle hole of the firing tube portion 11, and the front and rear ends respectively extend into the air chamber 13 and the action chamber 14.
  • the front end of the valve shaft 21 has a wide block 211 which can be controlled at the valve port 16. Opening and closing, the rear end is provided with a convex driving portion 212, and the valve block 211 can be provided with a first sealing ring 213 so that the valve port 16 can be controlled to be sealed, and the middle portion of the valve shaft 21 can be installed.
  • a second sealing ring 214 is for airtightly abutting between the inner wall of the middle hole of the firing tube portion 11 and the ceramic shaft 21.
  • the action plate 22 is pivotally disposed in the through hole 17 of the firing tube portion 11 through a pivot portion thereof.
  • the upper portion of the action plate 22 extends into the action chamber 14 to abut the driving portion 212 on the valve shaft 21.
  • the lower portion of the action plate 22 protrudes out through the through hole 17 of the firing tube portion 11, and the firing member 32 of the trigger unit 30 abuts against the rear end thereof.
  • the upper portion of the action plate 22 has a fork shape with an opening facing upward for the sleeve. It is connected to both sides of the valve shaft 21 and abuts the driving portion 212 laterally.
  • the adjusting block 24 has a screwing portion 241 for screwing into the screw hole 19 at the rear end of the firing tube portion 11.
  • the spring 23 is disposed at the two ends of the operating chamber 14 of the firing tube portion 11 and abuts between the valve shaft 21 and the adjusting block 24, and the adjusting block 24 screwed to the rear end of the firing tube portion 11 can be rotated to change position and adjust the spring. 23 The amount of spring applied to the valve shaft 21.
  • FIG. 2 to FIG. 7 or FIG. 9 to FIG. 11 for externally connecting the air inlet hole 18 of the gun body 10 to nitrogen, nitrogen, and the like.
  • the high-pressure gas is used as the power source, and the vaccine inlet 42 of the barrel 40 is externally connected to the vaccine source.
  • the gusset 31 of the trigger unit 30 is pressed, so that the gusset 31 has the dialing portion 311.
  • the passive portion 321 of the firing member 32 is pushed forward, and after the firing member 32 is rotated backward by an angle, the elastic force is supplied by the torsion spring 34, and the upper end portion of the firing member 32 is rotated against the action plate 22 to rotate the action plate 22.
  • valve shaft 21 is pushed back, so that the front end valve block 211 opens the valve port 16, so that the high pressure gas enters the barrel 40 through the gas chamber 13 and the valve port 16, wherein:
  • the gene gun forms a venturi structure inside the barrel 40, so that the high pressure gas accelerates when passing through the small hole section 411 in the middle thereof, and the fluid pressure at the small hole section 411 is small, so that the vaccine naturally
  • the vaccine inlet 42 is inhaled, and the vaccine is pushed into the target by the high pressure gas through the barrel 40.
  • the spring 23 is biased by the driving portion 212 of the valve shaft 21
  • the lower end of the action plate 22 is further abutted by the firing member 32 which is acted upon by the torsion spring 34, and the valve block at the front end of the valve shaft 21 is delayed by the force of the two portions being offset. 211 closes the valve port 16 time, thereby prolonging the action time of the high-pressure gas push vaccine, so that the vaccine can be deep to the target position, so that the accuracy of the vaccine injection operation is even more remarkable.
  • the firing control group 20 of the present invention can adjust the elastic force applied to the valve shaft 21 by the adjusting block 24 screwed to the rear end of the firing tube portion 11, thereby controlling the length of time for the valve block 211 to open the valve port 16, and further Adjusting the action time of controlling the high-pressure gas source enables the vaccine to be effectively controlled to the depth of the target, so that the effectiveness of the vaccine injection can be achieved to a better extent.
  • the gene gun includes a gun body 10, a barrel 40, and the present invention.
  • the firing control device includes a trigger unit 30 and a firing control group 20, wherein the composition of the gun body 10, the barrel 40, the trigger unit 30, and the firing control group 20 is substantially the same as that shown in FIG.
  • the preferred embodiment has the same structural design, and the same portions are not described herein again.
  • the gene gun different from the first preferred embodiment is:
  • the gun body 10 is axially disposed with a mounting hole 12 at the front end and an air chamber 13 at the rear end of the mounting hole 12, and the mounting hole 12 is connected to the connecting portion 43 of the barrel 40.
  • the mounting hole 12 is connected with the air chamber 13 to be connected with a valve port 16 , and an air inlet hole 18 is defined in the firing tube portion 11 opposite to the air chamber 13 .
  • the rear end of the plenum 13 forms a cornice.
  • the trigger unit 30 also includes a gusset 31, a firing member 32 and two torsion springs 33, 34.
  • the gusset 31 and the firing member 32 are each assembled in the gun body 10 by a pivotal coupling torque spring 33, 34.
  • the shank of the gusset 31 is extended outside the bottom end of the gun body 10.
  • the upper end of the firing member 32 extends toward the rear end opening of the plenum 13 of the firing tube portion 11.
  • the firing control group 20 is also mounted in the firing tube portion 11 of the gun body 10 and includes a valve shaft 21 and a spring 23, wherein:
  • the valve shaft 21 is movably assembled in the air chamber 13 of the firing tube portion 11, the outer diameter of which is slightly smaller than the diameter of the air chamber 13, and the front end of the valve shaft 21 has a larger outer diameter including the first sealing ring 213.
  • the valve block 211 can be controlled to open and close at the valve port 16, the rear end of the valve shaft 21 has a larger outer diameter striking portion 215 including a second sealing ring 214, and is airtightly movably disposed at the rear of the air chamber 13 And extending the rear end opening, the firing member 32 of the trigger unit 30 strikes the outer end portion.
  • the spring 23 is sleeved outside the valve shaft 21, and both ends abut against the inner wall of the firing tube portion 11 and the inner end portion of the striking portion 215.
  • FIG. 13 to FIG. 15 is a schematic view showing the operation of the second preferred embodiment of the firing control device of the present invention applied to a gene gun.
  • the air inlet 18 of the gun body 10 is externally connected with a high-pressure gas.
  • the power source, and the vaccine inlet 42 of the barrel 40 is externally connected to the vaccine source.
  • the spring force is provided by the torsion spring 34, so that the upper end portion of the firing member 32 is rotated against the rear end striking portion 215 of the valve shaft 21, thereby pushing the valve shaft 21 forward, so that the front end valve block 211 opens the valve port 16, so that the front end valve block 211 opens the valve port 16
  • the high pressure gas enters the barrel 40 via the plenum 13 and the valve port 16.
  • the firing control group 20 Since the spring 23 is compressed between the firing tube portion 11 and the strike portion 215 of the valve shaft 21, the firing member 32 acts as a two-force portion with respect to the torsion spring 34.
  • the parts are offset, thereby delaying the time when the valve block 211 at the front end of the valve shaft 21 closes the valve port 16, thereby prolonging the action time of the high-pressure gas push vaccine, so that the vaccine can be deepened to a predetermined position of the target, and the accuracy of the vaccine injection operation is made.

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Description

基因枪的击发控制装置 技术领域
本发明关于一种基因枪，特别是针对该基因枪中的击发控制装置所提出 的构造设计。 背景技术
基因枪是一种用于基因转殖等用途的工具， 其主要是利用高压气体（氦 气、 氮气等） 将附着于金属微粒（如钨、 金等高密度金属微粒）上的 DNA或 是疫苗推送入动植物的细胞深层中， 以克服细胞壁的生物限制， 目前被广泛 地应用于动植物的基因转殖、 基因治疗、 疫苗研究等方面。
有关前述基因枪的设计， 其主要是包括一气体管道外接高压气源， 以及 一基因枪本体， 该气体管道上设有控制组， 该基因枪本体设有一握把， 连接 一启动装置接合控制组， 且该基因枪本体上还设有喷布器以及送料机构等构 件， 并以该送料机构输入疫苗或 DNA等， 据此， 控制输入高压气体， 将该疫 苗或 DNA经由喷布器射向目标物。
但前述基因枪设计虽然是一项可将疫苗转殖入动植物中的器具， 然而， 该基因枪的击发控制组于每一次击发时， 该高压气体即快速地将该疫苗射入 动植物细胞后立即停止， 并未提供适当的后续推力， 造成该疫苗不易抵达目 标物的预定位置， 以致影响疫苗注射的成效。 发明内容
本发明的主要目的在于提供一种基因枪的击发控制装置，使其于基因枪 击发时， 可进一步提供后续推力， 使疫苗可被有效地控制而射入目标物的预 定位置处。
为达前述目的， 本发明所提出的基因枪的击发控制装置， 包括： 设于基 因枪枪体中的击发控制组及扳机组， 其中该击发控制组包括一阀轴、 一作用 板、 一弹簧及一调整块， 该阀轴气密地活动组设于该枪体的击发管部内， 该 阀轴前端具有阀块， 控制击发管部的阀口启闭， 该作用板枢设于该击发管部 内， 并上端连接阀轴， 下端伸出击发管部外连接扳机组中受扭力弹簧作用的 击发件， 该调整块具有螺接部， 可调整位置地螺设于击发管部后端， 该弹簧 设于击发管部内， 并抵接于阀轴后端与调整块之间； 或者， 使该击发控制组 包括一阀轴及一弹簧， 弹簧套设于阀轴上且抵接于击发管部与阀轴间， 并其 阀轴后端连接该扳机组中受扭力弹簧作用的击发件。
本发明通过前述技术方案， 将可达成的功效是： 当该击发控制装置应用 于基因枪后， 于击发时， 除可利用击发控制组控制高压气体的导入， 并对导 入枪体前端枪管中的疫苗提供动力射向目标物外， 本发明中的击发控制组更 通过其弹簧经阀轴顶抵作用板上端，与作用板下端另供受扭力弹簧作用的扳 机组所顶抵， 或是通过弹簧阀轴直接顶抵受扭力弹簧作用的扳机组， 通过两 者作用力部份相抵消， 延缓该阀轴前端阀块关闭击发管部的阀口时间， 进而 延长高压气体推送疫苗的作用时间， 使该疫苗可以深及至目标物预定位置。 附图说明
图 1 为本发明基因枪击发控制装置的第一较佳实施例应用于基因 枪中的平面示意图。
图 2〜6 为图 1 所示击发控制装置第一较佳实施例应用于基因枪中的 操作示意图。
图 7 为图 1 所示基因枪击发控制装置第一较佳实施例于调整弹力 大小的操作示意图。
图 8 为本发明基因枪击发控制装置第一较佳实施例应用于另一型 式基因枪中的平面示意图。
图 9〜11 为图 8所示击发控制装置第一较佳实施例应用于另一型式基 因枪中的操作示意图 图 12 为本发明基因枪击发控制装置的第二较佳实施例应用于基因 枪中的平面示意图。
图 13〜15为图 12所示击发控制装置第二较佳实施例应用于基因枪中的 操作示意图。
主要元件符号说明
10 … …枪体 11 … …击发管部
12 … …装配孔 13 … …气室
14 … …动作室 15 ·· …-中继块
16 … …阀口 17 … …通孔
18 … …进气孔 19 … …螺孔
20 … …击发控制组 21 … …阀轴
211 ··· …阀块 212··· …驱动部
213··· …第一密封环 214〜 …第二密封环
215- …触击部 22 … …作用板
23 … …弹簧 24 … …调整块
241 - …螺接部 34 … …扭力弹簧
30 … …扳机组 31 … …扣板
311〜 …拨动部 32 … …击发件
321— …被动部 33 … …扭力弹簧
40 … …枪管 41 … …管孔
411 - …小孔段 412〜 …扩张段
413- …扩张段 42 ·· …-疫苗入口
43 … …连接部 44 ·· …，连接件 具体实施方式 二基因枪中的平面示意图， 由图中可以见到， 该基因枪主要包括一枪体 10、 一枪管 40以及本发明的击发控制装置， 该击发控制装置包括一扳机组 30及 击发控制组 20， 其中：
该枪体 10内部上段具有一横向的击发管部 11，并于击发管部 11下方后 侧设有一枪柄， 该击发管部 11内部轴向依序设有一装配孔 12位于前端处、 一气室 13位于装配孔 12后方， 及一动作室 14位于气室 13后方， 该装配孔 12与气室 13之间设有一孔径略小的阀口 16相连通， 该阀口 16邻接气室 13 的一端可形成圆锥状， 该气室 13与动作室 14之间设有一孔径略小的中孔相 连通，其中可于该气室 13与动作室 14之间装设一中继块 15，该中孔设于该 中继块 15中， 连通气室 13与动作室 14， 且该击发管部 11上设有一自外侧 贯通至气室 13中的进气孔 18，供外接高压气源之用， 该击发管部 11上还设 有一通孔 17， 由击发管部 11底部向上连通至动作室 14前段， 该击发管部 11后端还设有一螺孔 19自外侧轴向连通至动作室 14。
前述中， 设于枪体 10中的进气孔 18设计， 可如图 1、 图 8等设计， 其 中如图 1所示的实施例， 该进气孔 18采取自击发管部 11的一侧边径向贯通 至气室 13中， 如图 8所示的实施例， 该进气孔 18则是自击发管部 11后端 朝前延伸再朝下贯通至气室 13。
该枪管 40后端具有一连接部 43， 用以组接于枪体 10前端的装配孔 12 中，该枪管 40中具有一轴向延伸的管孔 41，该管孔 41中段为一小孔段 411， 前后两区段分别形成朝外呈孔径逐渐加大的锥状扩张段 412、 413，而形成一 文氏管状， 该枪管 40中段另设有一小孔径的疫苗入口 42， 自外侧延伸至该 小孔段 411处， 又该疫苗入口 42还可加装一连接件 44， 用以外接基因源。
本发明的扳机组 30包括一扣板 31、 一击发件 32及二扭力弹簧 33、 34， 该扣板 31以其上端通过一枢柱配合扭力弹簧 33组装于枪体 10底部， 其柄 部伸出枪体 10底端外侧，该击发件 32以其下端通过一枢柱配合扭力弹簧 34 组设于枪体 10中， 且该击发件 32上端部伸向击发 部 11的通孔 17下方， 该扣板 31及击发件 32相邻端部处分别设有拨动部 311及被动部 321。
本发明的击发控制组 20装设于枪体 10的击发管部 11中， 其包括一阀 轴 21、 一作用板 22、 一弹簧 23及一调整块 24， 其中- 该阀轴 21以其中段气密地可活动组设于该击发管部 11的中孔中，并使 前后端分别伸向气室 13及动作室 14中， 该阀轴 21前端具有阔块 211可于 阀口 16处控制启闭，后端则设有一外凸的驱动部 212，又该阀块 211上可装 设一第一密封环 213， 使其可受控密封阀口 16， 该阀轴 21中段则可装设置 一第二密封环 214， 用以气密抵接于击发管部 11的中孔内壁与陶轴 21间。
该作用板 22以其中段通过一枢柱枢设于该击发管部 11的通孔 17中， 该作用板 22上段伸入动作室 14内，抵接该阀轴 21上的驱动部 212，该作用 板 22下段经由该击发管部 11的通孔 17伸出于外，供扳机组 30的击发件 32 抵接于其后端， 前述作用板 22上段为开口朝上的叉状， 用以套接于阀轴 21 两侧， 并侧向抵接驱动部 212。
该调整块 24—端具有螺接部 241， 用以螺接于击发管部 11后端的螺孔 19中。
该弹簧 23设于击发管部 11的动作室 14中两端抵接于阀轴 21与调整块 24之间，该螺接于击发管部 11后端的调整块 24可旋转前后改变位置，调整 弹簧 23施于阀轴 21的弹力大小。
有关前述击发控制装置第一较佳实施例应用于基因枪的使用操作情形， 请配合参阅图 2〜7或图 9〜11所示， 其令枪体 10的进气孔 18外接氦、 氮 等高压气体作为动力源， 另令枪管 40的疫苗入口 42外接疫苗源， 当使用者 以枪管瞄准目标物后， 按压扳机组 30的扣板 31， 使该扣板 31以其拨动部 311推抵击发件 32的被动部 321， 而使击发件 32先向后旋转一角度后， 再 通过扭力弹簧 34提供弹力，而使击发件 32上端部旋转撞击作用板 22，使该 作用板 22旋转而推动阀轴 21后移，使其前端阀块 211开启阀口 16，使高压 气体经由气室 13、 阀口 16进入枪管 40中， 其中： 该基因枪一方面通过枪管 40 内部形成文氏管构造， 使该高压气体通过 其中间的小孔段 411时产生加速作用， 以及该小孔段 411处流体压力较小， 使疫苗自然地自疫苗入口 42处被吸入， 进而使该疫苗经枪管 40由高压气体 推送下射入目标物； 另一方面， 该击发控制组 20中， 因有弹簧 23经阀轴 21 的驱动部 212顶抵着作用板 22上端， 该作用板 22下端另由受扭力弹簧 34 作用的击发件 32所顶抵， 因两者的作用力部份相抵消的情形下， 进而延缓 该阀轴 21前端的阀块 211关闭阀口 16的时间， 进而延长高压气体推送疫苗 的作用时间， 使该疫苗可以深及至目标物预定位置， 让疫苗注射操作的精准 性更 Ί王。
又本发明的击发控制组 20可透过螺接于击发管部 11后端的调整块 24 调整弹簧 23施于阀轴 21的弹力大小， 进而控制阀块 211幵启阀口 16的时 间长短， 进而调整控制高压气源的作用时间， 使该疫苗可被有效地控制射入 目标物的深度， 使疫苗注射的成效达到较佳的程度。
如图 12所示， 为本发明击发控制装置第二较佳实施例应用于基因枪的 平面示意图， 由图中可以见到， 该基因枪包括一枪体 10、 一枪管 40以及本 发明的击发控制装置，该击发控制装置包括一扳机组 30及一击发控制组 20， 其中枪体 10、 枪管 40、 扳机组 30及击发控制组 20的组成构造大致上概与 图 1所示第一较佳实施例相对应构造设计相同， 其中相同的部份在此即不再 赘述， 至于不同于第一较佳实施例的基因枪之处在于：
该枪体 10于其击发管部 11 内部轴向依序设有一位于前端的装配孔 12 以及一气室 13位于装配孔 12后端， 该装配孔 12供枪管 40的连接部 43组 接其中， 该装配孔 12与气室 13之间设有一阀口 16相连通， 且该击发管部 11中相对于气室 13上方设有一进气孔 18自后端朝前延伸一段距离后朝下延 伸连通气室 13中段， 该气室 13后端形成幵口。
该扳机组 30同样包括一扣板 31、 一击发件 32及二扭力弹簧 33、 34, 该扣板 31及击发件 32各通过一枢柱结合扭力弹簧 33、34组装于枪体 10中， 并使扣板 31的柄部伸出枪体 10底端外侧， 该击发件 32上端部伸向击发管 部 11气室 13后端开口处。
该击发控制组 20同样装设于枪体 10的击发管部 11中， 其包括一阀轴 21及一弹簧 23， 其中：
该阀轴 21可活动地组设于该击发管部 11的气室 13中， 其外径略小于 气室 13孔径， 该阀轴 21前端具有一包含有第一密封环 213的较大外径阀块 211可于阀口 16处控制启闭， 阀轴 21后端具有一包含有第二密封环 214的 较大外径触击部 215 , 且气密可活动地设置于气室 13后段并伸出后端开口 夕卜， 可供扳机组 30的击发件 32触击其外端部。
该弹簧 23套设于该阀轴 21外， 且两端抵接于击发管部 11内壁以及触 击部 215的内端部。
如图 13至图 15所示， 为本发明击发控制装置第二较佳实施例应用于基 因枪的使用操作示意图， 由图中可以见到， 该枪体 10的进气孔 18外接高压 气体作为动力源， 另以枪管 40的疫苗入口 42外接疫苗源， 当使用者以枪管 瞄准目标物后， 按压扳机组 30的扣板 31， 使该扣板 31推抵击发件 32先向 后旋转一角度后， 再通过扭力弹簧 34提供弹力， 使击发件 32上端部旋转撞 击阀轴 21后端触击部 215， 进而推动阀轴 21前移， 使其前端阀块 211开启 阀口 16， 使高压气体经由气室 13、 阀口 16进入枪管 40中。
当该高压气体进入枪管 40后， 通过其内部文氏管构造产生加速作用， 并使疫苗自疫苗入口 42处被吸入， 进而使疫苗经枪管 40由高压气体推送下 射入目标物； 另一方面， 该击发控制组 20中， 因其弹簧 23被压缩于击发管 部 11与阀轴 21的触击部 215之间， 相对于受扭力弹簧 34作用的击发件 32 间呈二作用力部份相抵消， 进而延缓该阀轴 21前端的阀块 211关闭阀口 16 的时间， 进而延长高压气体推送疫苗的作用时间， 使该疫苗可以深及至目标 物预定位置， 让疫苗注射操作的精准性更佳。

Claims

权 利 要 求 书
1. 一种基因枪的击发控制装置， 包括一击发控制组设于基因枪枪体的 击发管部中， 以及一扳机组设于枪体中的击发管部下方， 其特征是： 该击发 控制组包括一阀轴、 一作用板、 一弹簧及一调整块， 该阀轴气密且可活动地 组设于该击发 部内， 该阀轴前端具有一阀块， 用以控制击发管部的阀口启 闭， 该作用板枢设于该击发管部内且以一端连接于阀轴， 该调整块具有螺接 部， 可调整位置地螺设于击发管部后端， 该弹簧设于击发管部内， 抵接于阀 轴后端与调整块之间； 该扳机组包括一扣板、 一击发件及二扭力弹簧， 该扣 板及击发件各结合一扭力弹簧相对枢设于枪体中， 该击发件上端伸向击发管 部抵接作用板。
2. 如权利要求 1所述的基因枪的击发控制装置， 其特征是： 该阀轴后 端设有一外凸的驱动部，该作用板上端为开口朝上的叉状，套接于阀轴两侧， 并侧向抵接该驱动部。
3. 如权利要求 1或 2所述的基因枪的击发控制装置， 其特征是： 该阀 块上装设一第一密封环。
4. 如权利要求 1或 2所述的基因枪的击发控制装置， 其特征是： 该阀 轴中段设有一第二密封环， 用以气密抵接于击发管部内壁。
5. 一种基因枪的击发控制装置， 包括一击发控制组设于基因枪枪体的 击发管部中， 以及一扳机组设于枪体中的击发管部下方， 其特征是： 该击发 控制组包括一阀轴可活动地组设于该击发管部内， 以及一弹簧套设于阀轴上 抵接于击发管部与阀轴间， 该阀轴前端具有阀块， 用以控制击发管部的阀口 启闭， 该阀轴后端具有一触击部气密且可活动地伸出击发管部后端外， 该扳 机组包括一扣板、 一击发件及二扭力弹簧， 该扣板及击发件各结合一扭力弹 簧相对枢设于枪体中， 该扣板的柄部伸出枪体外， 该击发件上端伸向击发管 部后端抵接触击部。
6. 如权利要求 5所述的基因枪的击发控制装置， 其特征是： 该阀块及 触击部上各设有一密封环， 用以气密抵接于击发管部内壁。
PCT/CN2006/002129 2006-08-22 2006-08-22 A percussion-controlling device of gene gun Ceased WO2008031257A1 (en)

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Citations (5)

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Publication number Priority date Publication date Assignee Title
CN1305006A (zh) * 2001-02-27 2001-07-25 周芳 一种台式气体基因枪
CN1305007A (zh) * 2001-02-27 2001-07-25 周芳 一种手枪式气体基因枪
US6436709B1 (en) * 2001-10-19 2002-08-20 Bioware Technology Co., Ltd. Low pressure-accelerated particle gene gun
CN1475277A (zh) * 2003-07-04 2004-02-18 清华大学 纱窗式整流加速基因微弹的方法及基因枪
EP1444999A1 (en) * 2003-02-03 2004-08-11 BioWare Technology Co., Ltd Low pressure gas accelerated gene gun

Patent Citations (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1305006A (zh) * 2001-02-27 2001-07-25 周芳 一种台式气体基因枪
CN1305007A (zh) * 2001-02-27 2001-07-25 周芳 一种手枪式气体基因枪
US6436709B1 (en) * 2001-10-19 2002-08-20 Bioware Technology Co., Ltd. Low pressure-accelerated particle gene gun
EP1444999A1 (en) * 2003-02-03 2004-08-11 BioWare Technology Co., Ltd Low pressure gas accelerated gene gun
CN1475277A (zh) * 2003-07-04 2004-02-18 清华大学 纱窗式整流加速基因微弹的方法及基因枪

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