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WO2008030818A3 - Nouvelles compositions de liposomes - Google Patents

Nouvelles compositions de liposomes Download PDF

Info

Publication number
WO2008030818A3
WO2008030818A3 PCT/US2007/077548 US2007077548W WO2008030818A3 WO 2008030818 A3 WO2008030818 A3 WO 2008030818A3 US 2007077548 W US2007077548 W US 2007077548W WO 2008030818 A3 WO2008030818 A3 WO 2008030818A3
Authority
WO
WIPO (PCT)
Prior art keywords
liposome compositions
novel liposome
containing compositions
lipid
targeted liposomes
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Ceased
Application number
PCT/US2007/077548
Other languages
English (en)
Other versions
WO2008030818A2 (fr
Inventor
Yusuke Miyajima
Kazushi Okada
Naoyuki Morisaki
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Mebiopharm Co Ltd
Original Assignee
Mebiopharm Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Mebiopharm Co Ltd filed Critical Mebiopharm Co Ltd
Publication of WO2008030818A2 publication Critical patent/WO2008030818A2/fr
Publication of WO2008030818A3 publication Critical patent/WO2008030818A3/fr
Anticipated expiration legal-status Critical
Ceased legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/10—Dispersions; Emulsions
    • A61K9/127—Synthetic bilayered vehicles, e.g. liposomes or liposomes with cholesterol as the only non-phosphatidyl surfactant

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Dispersion Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)

Abstract

Cette invention concerne des compositions contenant des lipides, dont des liposomes ciblés encapsulant du méthotrexate, et des préparations pharmaceutiques de ces compositions, ainsi que des méthodes de fabrication et d'utilisation des compositions contenant des lipides, y compris l'utilisation de liposomes ciblés pour le traitement du cancer, de la polyarthrite rhumatoïde et d'autres pathologies.
PCT/US2007/077548 2006-09-05 2007-09-04 Nouvelles compositions de liposomes Ceased WO2008030818A2 (fr)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
US84246706P 2006-09-05 2006-09-05
US60/842,467 2006-09-05
US90527007P 2007-03-05 2007-03-05
US60/905,270 2007-03-05

Publications (2)

Publication Number Publication Date
WO2008030818A2 WO2008030818A2 (fr) 2008-03-13
WO2008030818A3 true WO2008030818A3 (fr) 2008-06-05

Family

ID=39157979

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/US2007/077548 Ceased WO2008030818A2 (fr) 2006-09-05 2007-09-04 Nouvelles compositions de liposomes

Country Status (1)

Country Link
WO (1) WO2008030818A2 (fr)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7829113B2 (en) 2005-03-10 2010-11-09 Mebiopharm Co., Ltd. Liposome compositions

Families Citing this family (24)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US9770414B2 (en) * 2010-05-13 2017-09-26 Pacira Pharmaceuticals, Inc. Sustained release formulation of methotrexate as a disease-modifying antirheumatic drug (DMARD) and an anti-cancer agent
US10610486B2 (en) 2010-10-28 2020-04-07 Pacira Pharmaceuticals, Inc. Sustained release formulation of a non-steroidal anti-inflammatory drug
JP6535281B2 (ja) 2012-07-05 2019-06-26 タイワン リポソーム カンパニー リミテッド 関節炎の処置方法
SG11201501010QA (en) 2012-08-10 2015-04-29 Taiho Pharmaceutical Co Ltd Stable oxaliplatin-encapsulating liposome aqueous dispersion and method for stabilizing same
WO2018031968A1 (fr) 2016-08-12 2018-02-15 L.E.A.F. Holdings Group Llc Antifolates polyglutamés alpha et gamma-d et leurs utilisations
CA3177187A1 (fr) 2016-08-12 2018-02-15 L.E.A.F Holdings Group Llc Antifolates alpha et gamma-d de polyglutamates et leurs utilisations
EP3541815A4 (fr) 2016-11-18 2020-07-15 Pacira Pharmaceuticals, Inc. Formulations de liposomes multivésiculaires à microparticules de complexe de méloxicam de zinc et leurs procédés de fabrication
CN108553420A (zh) * 2017-11-20 2018-09-21 平顶山学院 一种口服甲氨蝶呤脂质体及其制备方法
CN111954530A (zh) 2018-02-07 2020-11-17 L.E.A.F.控股集团公司 γ聚谷氨酸化培美曲塞及其用途
CA3090384A1 (fr) 2018-02-07 2019-08-15 L.E.A.F. Holdings Group Llc Aminopterine alpha-polyglutamatee et utilisations associees
EP3749318A4 (fr) 2018-02-07 2022-07-06 L.E.A.F Holdings Group LLC Raltitrexed gamma-polyglutamaté et utilisations associées
WO2019157133A1 (fr) 2018-02-07 2019-08-15 L.E.A.F. Holdings Group Llc Raltitrexed alpha-polyglutamaté et utilisations associées
US12220431B2 (en) 2018-02-07 2025-02-11 L.E.A.F. Holdings Group Llc Gamma polyglutamated antifolates and uses thereof
CA3090381A1 (fr) 2018-02-07 2019-08-15 L.E.A.F. Holdings Group Llc Lometrexol alpha-polyglutamate et utilisations associees
JP7491573B2 (ja) 2018-02-07 2024-05-28 エル．イー．エー．エフ． ホールディングス グループ エルエルシー アルファポリグルタミン酸化メトトレキセートおよびその使用
CN111954531A (zh) 2018-02-07 2020-11-17 L.E.A.F.控股集团公司 α聚谷氨酸化培美曲塞及其用途
US11730738B2 (en) 2018-02-07 2023-08-22 L.E.A.F. Holdings Group Llc Alpha polyglutamated pralatrexate and uses thereof
US12076402B2 (en) 2018-02-07 2024-09-03 L.E.A.F. Holdings Group Llc Alpha polyglutamated antifolates and uses thereof
CA3090506A1 (fr) 2018-02-07 2019-08-15 L.E.A.F. Holdings Group Llc Tetrahydrofolates alpha polyglutames et leurs utilisations
US12048766B2 (en) 2018-02-14 2024-07-30 L.E.A.F. Holdings Group Llc Gamma polyglutamated tetrahydrofolates and uses thereof
WO2019160733A1 (fr) 2018-02-14 2019-08-22 L.E.A.F. Holdings Group Llc Méthotrexate gamma polyglutamique et ses utilisations
US12048767B2 (en) 2018-02-14 2024-07-30 L.E.A.F. Holdings Group Llc Gamma polyglutamated pralatrexate and uses thereof
CA3090943A1 (fr) 2018-02-14 2019-08-22 L.E.A.F. Holdings Group Llc Aminopterine gamma polyglutamique et ses utilisations
WO2019160734A1 (fr) 2018-02-14 2019-08-22 L.E.A.F. Holdings Group Llc Lométrexol gamma polyglutamique et ses utilisations

Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6294191B1 (en) * 1996-10-15 2001-09-25 The Liposome Company, Inc. N-acyl phosphatidylethanolamine-mediated liposomal drug delivery

Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6294191B1 (en) * 1996-10-15 2001-09-25 The Liposome Company, Inc. N-acyl phosphatidylethanolamine-mediated liposomal drug delivery

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7829113B2 (en) 2005-03-10 2010-11-09 Mebiopharm Co., Ltd. Liposome compositions
US8758810B2 (en) 2005-03-10 2014-06-24 Mebiopharm Co., Ltd. Liposome compositions

Also Published As

Publication number Publication date
WO2008030818A2 (fr) 2008-03-13

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