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WO2008030818A3 - Nouvelles compositions de liposomes - Google Patents

Nouvelles compositions de liposomes Download PDF

Info

Publication number
WO2008030818A3
WO2008030818A3 PCT/US2007/077548 US2007077548W WO2008030818A3 WO 2008030818 A3 WO2008030818 A3 WO 2008030818A3 US 2007077548 W US2007077548 W US 2007077548W WO 2008030818 A3 WO2008030818 A3 WO 2008030818A3
Authority
WO
WIPO (PCT)
Prior art keywords
liposome compositions
novel liposome
containing compositions
lipid
targeted liposomes
Prior art date
Application number
PCT/US2007/077548
Other languages
English (en)
Other versions
WO2008030818A2 (fr
Inventor
Yusuke Miyajima
Kazushi Okada
Naoyuki Morisaki
Original Assignee
Mebiopharm Co Ltd
Yusuke Miyajima
Kazushi Okada
Naoyuki Morisaki
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Mebiopharm Co Ltd, Yusuke Miyajima, Kazushi Okada, Naoyuki Morisaki filed Critical Mebiopharm Co Ltd
Publication of WO2008030818A2 publication Critical patent/WO2008030818A2/fr
Publication of WO2008030818A3 publication Critical patent/WO2008030818A3/fr

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/10—Dispersions; Emulsions
    • A61K9/127—Synthetic bilayered vehicles, e.g. liposomes or liposomes with cholesterol as the only non-phosphatidyl surfactant

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Dispersion Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)

Abstract

Cette invention concerne des compositions contenant des lipides, dont des liposomes ciblés encapsulant du méthotrexate, et des préparations pharmaceutiques de ces compositions, ainsi que des méthodes de fabrication et d'utilisation des compositions contenant des lipides, y compris l'utilisation de liposomes ciblés pour le traitement du cancer, de la polyarthrite rhumatoïde et d'autres pathologies.
PCT/US2007/077548 2006-09-05 2007-09-04 Nouvelles compositions de liposomes WO2008030818A2 (fr)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
US84246706P 2006-09-05 2006-09-05
US60/842,467 2006-09-05
US90527007P 2007-03-05 2007-03-05
US60/905,270 2007-03-05

Publications (2)

Publication Number Publication Date
WO2008030818A2 WO2008030818A2 (fr) 2008-03-13
WO2008030818A3 true WO2008030818A3 (fr) 2008-06-05

Family

ID=39157979

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/US2007/077548 WO2008030818A2 (fr) 2006-09-05 2007-09-04 Nouvelles compositions de liposomes

Country Status (1)

Country Link
WO (1) WO2008030818A2 (fr)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7829113B2 (en) 2005-03-10 2010-11-09 Mebiopharm Co., Ltd. Liposome compositions

Families Citing this family (24)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US9770414B2 (en) * 2010-05-13 2017-09-26 Pacira Pharmaceuticals, Inc. Sustained release formulation of methotrexate as a disease-modifying antirheumatic drug (DMARD) and an anti-cancer agent
US10610486B2 (en) 2010-10-28 2020-04-07 Pacira Pharmaceuticals, Inc. Sustained release formulation of a non-steroidal anti-inflammatory drug
HUE062466T2 (hu) 2012-07-05 2023-11-28 Taiwan Liposome Co Ltd Eljárások arthritis kezelésére
SG11201501010QA (en) 2012-08-10 2015-04-29 Taiho Pharmaceutical Co Ltd Stable oxaliplatin-encapsulating liposome aqueous dispersion and method for stabilizing same
US20180236098A1 (en) 2016-08-12 2018-08-23 L.E.A.F. Holdings Group Llc Alpha and gamma-d polyglutamated antifolates and uses thereof
EP3496756A4 (fr) 2016-08-12 2020-07-22 L.E.A.F Holdings Group LLC Antifolates alpha et gamma-d de polyglutamates et leurs utilisations.
CN109983013A (zh) 2016-11-18 2019-07-05 帕西拉制药有限公司 美洛昔康锌复合物微粒多囊脂质体制剂及其制备方法
CN115475142A (zh) * 2017-11-20 2022-12-16 平顶山学院 一种口服甲氨蝶呤脂质体及其制备方法
CA3090391A1 (fr) 2018-02-07 2019-08-15 L.E.A.F. Holdings Group Llc Raltitrexed gamma-polyglutamate et utilisations associees
US11730738B2 (en) 2018-02-07 2023-08-22 L.E.A.F. Holdings Group Llc Alpha polyglutamated pralatrexate and uses thereof
JP7490239B2 (ja) 2018-02-07 2024-05-27 エル．イー．エー．エフ． ホールディングス グループ エルエルシー ガンマポリグルタミン酸化ペメトレキセドおよびその使用
US12246015B2 (en) 2018-02-07 2025-03-11 L.E.A.F. Holdings Group Llc Alpha polyglutamated raltitrexed and uses thereof
US12220431B2 (en) 2018-02-07 2025-02-11 L.E.A.F. Holdings Group Llc Gamma polyglutamated antifolates and uses thereof
WO2019157123A1 (fr) 2018-02-07 2019-08-15 L.E.A.F. Holdings Group Llc Aminoptérine alpha-polyglutamatée et utilisations associées
CA3090494A1 (fr) 2018-02-07 2019-08-15 L.E.A.F. Holdings Group Llc Pemetrexed alpha-polyglutamate et utilisations associees
EP3749312A4 (fr) 2018-02-07 2022-02-23 L.E.A.F Holdings Group LLC Lométrexol alpha-polyglutamaté et utilisations associées
EP3749313A4 (fr) 2018-02-07 2022-03-16 L.E.A.F Holdings Group LLC Antifolates alpha-polyglutamatés et utilisations associées
CN111954529A (zh) 2018-02-07 2020-11-17 L.E.A.F.控股集团公司 α聚谷氨酸化氨甲蝶呤及其用途
EP3749319A4 (fr) 2018-02-07 2022-06-22 L.E.A.F Holdings Group LLC Tétrahydrofolates alpha polyglutamés et leurs utilisations
US12350271B2 (en) 2018-02-14 2025-07-08 L.E.A.F. Holdings Group Llc Gamma polyglutamated aminopterin and uses thereof
CA3090992A1 (fr) 2018-02-14 2019-08-22 L.E.A.F. Holdings Group Llc Tetrahydrofolates gamma polyglutamiques et leurs utilisations
US11771700B2 (en) 2018-02-14 2023-10-03 L.E.A.F. Holdings Group Llc Gamma polyglutamated lometrexol and uses thereof
CN111936145A (zh) 2018-02-14 2020-11-13 L.E.A.F.控股集团公司 γ聚谷氨酸化氨甲蝶呤及其用途
EP3752156A4 (fr) 2018-02-14 2021-10-27 L.E.A.F Holdings Group LLC Pralatrexate gamma-polyglutamaté et utilisations associées

Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6294191B1 (en) * 1996-10-15 2001-09-25 The Liposome Company, Inc. N-acyl phosphatidylethanolamine-mediated liposomal drug delivery

Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6294191B1 (en) * 1996-10-15 2001-09-25 The Liposome Company, Inc. N-acyl phosphatidylethanolamine-mediated liposomal drug delivery

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7829113B2 (en) 2005-03-10 2010-11-09 Mebiopharm Co., Ltd. Liposome compositions
US8758810B2 (en) 2005-03-10 2014-06-24 Mebiopharm Co., Ltd. Liposome compositions

Also Published As

Publication number Publication date
WO2008030818A2 (fr) 2008-03-13

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