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WO2008026048A3 - Compositions pharmaceutiques injectables stables de docétaxel - Google Patents

Compositions pharmaceutiques injectables stables de docétaxel Download PDF

Info

Publication number
WO2008026048A3
WO2008026048A3 PCT/IB2007/002495 IB2007002495W WO2008026048A3 WO 2008026048 A3 WO2008026048 A3 WO 2008026048A3 IB 2007002495 W IB2007002495 W IB 2007002495W WO 2008026048 A3 WO2008026048 A3 WO 2008026048A3
Authority
WO
WIPO (PCT)
Prior art keywords
docetaxel
pharmaceutical compositions
injectable pharmaceutical
stable injectable
stable
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Ceased
Application number
PCT/IB2007/002495
Other languages
English (en)
Other versions
WO2008026048A2 (fr
Inventor
Bhaveshkumar Vallabhbhai Patel
Amit Gupta
Bhushan Subhash Yeola
Ranjith K. Kumar
Girish Kumar Jain
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Wockhardt Research Centre
Original Assignee
Wockhardt Research Centre
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Wockhardt Research Centre filed Critical Wockhardt Research Centre
Publication of WO2008026048A2 publication Critical patent/WO2008026048A2/fr
Anticipated expiration legal-status Critical
Publication of WO2008026048A3 publication Critical patent/WO2008026048A3/fr
Ceased legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
    • A61K47/12—Carboxylic acids; Salts or anhydrides thereof

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Engineering & Computer Science (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Dermatology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)

Abstract

La présente invention concerne des compositions pharmaceutiques injectables stables de docétaxel ou de sels de celui-ci, comprenant une solution mère et une solution de diluant, la solution mère comprenant du docétaxel ou des sels de celui-ci ainsi que des excipients acceptables du point de vue pharmaceutique et de l'éthanol et la solution de diluant étant essentiellement constituée d'eau. La présente invention concerne également des compositions pharmaceutiques injectables stables de docétaxel, caractérisées en ce que leur pH est maintenu à une valeur comprise entre environ 3 et environ 6.
PCT/IB2007/002495 2006-08-31 2007-08-30 Compositions pharmaceutiques injectables stables de docétaxel Ceased WO2008026048A2 (fr)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
IN1391/MUM/2006 2006-08-31
IN1384MU2006 2006-08-31
IN1384/MUM/2006 2006-08-31
IN1391MU2006 2006-08-31

Publications (2)

Publication Number Publication Date
WO2008026048A2 WO2008026048A2 (fr) 2008-03-06
WO2008026048A3 true WO2008026048A3 (fr) 2009-08-27

Family

ID=39136321

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/IB2007/002495 Ceased WO2008026048A2 (fr) 2006-08-31 2007-08-30 Compositions pharmaceutiques injectables stables de docétaxel

Country Status (1)

Country Link
WO (1) WO2008026048A2 (fr)

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US8940786B2 (en) 2012-10-01 2015-01-27 Teikoku Pharma Usa, Inc. Non-aqueous taxane nanodispersion formulations and methods of using the same
US10842770B2 (en) 2010-05-03 2020-11-24 Teikoku Pharma Usa, Inc. Non-aqueous taxane pro-emulsion formulations and methods of making and using the same

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2010023321A1 (fr) * 2008-09-01 2010-03-04 Stragen Pharma S.A. Formulation liquide contenant un dérivé taxane
EP2204167A1 (fr) 2009-01-05 2010-07-07 Azad Pharma AG Microémulsion pharmaceutique pour la prévention de l'agrégation supramoléculaire de molécules amphiphiles
KR101074936B1 (ko) * 2009-05-25 2011-10-18 보령제약 주식회사 도세탁셀 주사제용 조성물 및 그의 제조방법
US8476310B2 (en) 2009-10-19 2013-07-02 Scidose Llc Docetaxel formulations with lipoic acid
US7772274B1 (en) 2009-10-19 2010-08-10 Scidose, Llc Docetaxel formulations with lipoic acid
US8912228B2 (en) 2009-10-19 2014-12-16 Scidose Llc Docetaxel formulations with lipoic acid
JP6076744B2 (ja) * 2013-01-04 2017-02-08 ナガセ医薬品株式会社 ドセタキセル含有医薬組成物
CN111557934A (zh) * 2020-06-10 2020-08-21 四川汇宇制药股份有限公司 一种含多西他赛的药物组合物及其制备方法和用途

Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5403858A (en) * 1991-07-08 1995-04-04 Rhone-Poulenc Rorer, S.A. New compositions containing taxane derivatives
US5750561A (en) * 1991-07-08 1998-05-12 Rhone-Poulenc Rorer, S.A. Compositions containing taxane derivatives
US5977163A (en) * 1996-03-12 1999-11-02 Pg-Txl Company, L. P. Water soluble paclitaxel prodrugs

Patent Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5403858A (en) * 1991-07-08 1995-04-04 Rhone-Poulenc Rorer, S.A. New compositions containing taxane derivatives
US5750561A (en) * 1991-07-08 1998-05-12 Rhone-Poulenc Rorer, S.A. Compositions containing taxane derivatives
US5977163A (en) * 1996-03-12 1999-11-02 Pg-Txl Company, L. P. Water soluble paclitaxel prodrugs

Cited By (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US10842770B2 (en) 2010-05-03 2020-11-24 Teikoku Pharma Usa, Inc. Non-aqueous taxane pro-emulsion formulations and methods of making and using the same
US8940786B2 (en) 2012-10-01 2015-01-27 Teikoku Pharma Usa, Inc. Non-aqueous taxane nanodispersion formulations and methods of using the same
US9308195B2 (en) 2012-10-01 2016-04-12 Teikoku Pharma Usa, Inc. Non-aqueous taxane formulations and methods of using the same
US9763880B2 (en) 2012-10-01 2017-09-19 Teikoku Pharma Usa, Inc. Non-aqueous taxane formulations and methods of using the same

Also Published As

Publication number Publication date
WO2008026048A2 (fr) 2008-03-06

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