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WO2008019070A3 - Pharmaceutical compositions of trospium for treating smooth muscle hyperactivity disorders - Google Patents

Pharmaceutical compositions of trospium for treating smooth muscle hyperactivity disorders Download PDF

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Publication number
WO2008019070A3
WO2008019070A3 PCT/US2007/017353 US2007017353W WO2008019070A3 WO 2008019070 A3 WO2008019070 A3 WO 2008019070A3 US 2007017353 W US2007017353 W US 2007017353W WO 2008019070 A3 WO2008019070 A3 WO 2008019070A3
Authority
WO
WIPO (PCT)
Prior art keywords
smooth muscle
trospium
pharmaceutical compositions
hyperactivity disorders
muscle hyperactivity
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Ceased
Application number
PCT/US2007/017353
Other languages
French (fr)
Other versions
WO2008019070A2 (en
Inventor
Ebrahim Versi
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Individual
Original Assignee
Individual
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Individual filed Critical Individual
Publication of WO2008019070A2 publication Critical patent/WO2008019070A2/en
Publication of WO2008019070A3 publication Critical patent/WO2008019070A3/en
Anticipated expiration legal-status Critical
Ceased legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/47—Quinolines; Isoquinolines
    • A61K31/4747—Quinolines; Isoquinolines spiro-condensed

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

Pharmaceutical compositions and methods are disclosed using trospium and/or its metabolites, and pro-drugs with antimuscarinic smooth muscle relaxant properties, administered as a subcutaneous injection, implant or other depot preparation for the treatment of urinary incontinence, and other smooth muscle hyperactivity disorders thus avoiding the poor bioavailability of oral administration.
PCT/US2007/017353 2006-08-04 2007-08-03 Pharmaceutical compositions of trospium for treating smooth muscle hyperactivity disorders Ceased WO2008019070A2 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US83551606P 2006-08-04 2006-08-04
US60/835,516 2006-08-04

Publications (2)

Publication Number Publication Date
WO2008019070A2 WO2008019070A2 (en) 2008-02-14
WO2008019070A3 true WO2008019070A3 (en) 2008-04-24

Family

ID=39033495

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/US2007/017353 Ceased WO2008019070A2 (en) 2006-08-04 2007-08-03 Pharmaceutical compositions of trospium for treating smooth muscle hyperactivity disorders

Country Status (1)

Country Link
WO (1) WO2008019070A2 (en)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU2016279798B2 (en) * 2015-06-15 2021-07-08 Qaam Pharmaceuticals, Llc Glycopyrronium fatty acid salts and methods of making same

Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5998430A (en) * 1996-11-27 1999-12-07 Dr. R. Pfleger Chemische Fabrik Gmbh Use of trospium chloride and 2-component system for the same
US6974820B2 (en) * 2002-11-06 2005-12-13 Bridge Pharma, Inc. Methods for treating urinary incontinence and other disorders using trospium

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5998430A (en) * 1996-11-27 1999-12-07 Dr. R. Pfleger Chemische Fabrik Gmbh Use of trospium chloride and 2-component system for the same
US6974820B2 (en) * 2002-11-06 2005-12-13 Bridge Pharma, Inc. Methods for treating urinary incontinence and other disorders using trospium

Also Published As

Publication number Publication date
WO2008019070A2 (en) 2008-02-14

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