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WO2008017466A8 - Dérivés de benzimidazole pharmaceutiquement actifs substitués par la tétrahydroisoquinoléine - Google Patents

Dérivés de benzimidazole pharmaceutiquement actifs substitués par la tétrahydroisoquinoléine

Info

Publication number
WO2008017466A8
WO2008017466A8 PCT/EP2007/007007 EP2007007007W WO2008017466A8 WO 2008017466 A8 WO2008017466 A8 WO 2008017466A8 EP 2007007007 W EP2007007007 W EP 2007007007W WO 2008017466 A8 WO2008017466 A8 WO 2008017466A8
Authority
WO
WIPO (PCT)
Prior art keywords
pharmaceutically active
benzimidazole derivatives
substituted benzimidazole
tetrahydroisoquinoline
active tetrahydroisoquinoline
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Ceased
Application number
PCT/EP2007/007007
Other languages
English (en)
Other versions
WO2008017466A1 (fr
Inventor
Peter Jan Zimmermann
Christof Brehm
Wilm Buhr
Andreas Palmer
Saskia Zemolka
Wolfgang-Alexander Simon
Stefan Postius
Wolfgang Kromer
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Takeda GmbH
Original Assignee
Nycomed GmbH
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Nycomed GmbH filed Critical Nycomed GmbH
Publication of WO2008017466A1 publication Critical patent/WO2008017466A1/fr
Publication of WO2008017466A8 publication Critical patent/WO2008017466A8/fr
Anticipated expiration legal-status Critical
Ceased legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/04—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/14—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing three or more hetero rings

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Engineering & Computer Science (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

L'invention concerne des composés de formule (1) dont les substituants et symboles sont tels que définis dans la description. Les composés inhibent la sécrétion de l'acide gastrique.
PCT/EP2007/007007 2006-08-08 2007-08-08 Dérivés de benzimidazole pharmaceutiquement actifs substitués par la tétrahydroisoquinoléine Ceased WO2008017466A1 (fr)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP06118597.1 2006-08-08
EP06118597 2006-08-08

Publications (2)

Publication Number Publication Date
WO2008017466A1 WO2008017466A1 (fr) 2008-02-14
WO2008017466A8 true WO2008017466A8 (fr) 2008-03-20

Family

ID=37733683

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/EP2007/007007 Ceased WO2008017466A1 (fr) 2006-08-08 2007-08-08 Dérivés de benzimidazole pharmaceutiquement actifs substitués par la tétrahydroisoquinoléine

Country Status (1)

Country Link
WO (1) WO2008017466A1 (fr)

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AR043063A1 (es) * 2002-12-13 2005-07-13 Altana Pharma Ag Bencimidazoles 6-sustituidos y su uso como inhibidores de secreciones gastricas
PL1784402T3 (pl) * 2004-09-03 2011-12-30 Yuhan Corp Pochodne pirolo[3,2-c]pirydyny oraz sposoby ich wytwarzania

Also Published As

Publication number Publication date
WO2008017466A1 (fr) 2008-02-14

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