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WO2008016984A3 - Polysaccharide vaccine and uses thereof - Google Patents

Polysaccharide vaccine and uses thereof Download PDF

Info

Publication number
WO2008016984A3
WO2008016984A3 PCT/US2007/074985 US2007074985W WO2008016984A3 WO 2008016984 A3 WO2008016984 A3 WO 2008016984A3 US 2007074985 W US2007074985 W US 2007074985W WO 2008016984 A3 WO2008016984 A3 WO 2008016984A3
Authority
WO
WIPO (PCT)
Prior art keywords
polysaccharide vaccine
polysaccharide
compositions
alp3
elicit
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Ceased
Application number
PCT/US2007/074985
Other languages
French (fr)
Other versions
WO2008016984A2 (en
Inventor
Lawrence C Madoff
Lawrence Paoletti
Dennis L Kasper
Catherine Lachenauer
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Brigham and Womens Hospital Inc
Original Assignee
Brigham and Womens Hospital Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Brigham and Womens Hospital Inc filed Critical Brigham and Womens Hospital Inc
Publication of WO2008016984A2 publication Critical patent/WO2008016984A2/en
Publication of WO2008016984A3 publication Critical patent/WO2008016984A3/en
Anticipated expiration legal-status Critical
Ceased legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/02—Bacterial antigens
    • A61K39/09—Lactobacillales, e.g. aerococcus, enterococcus, lactobacillus, lactococcus, streptococcus
    • A61K39/092—Streptococcus
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/60—Medicinal preparations containing antigens or antibodies characteristics by the carrier linked to the antigen
    • A61K2039/6031—Proteins

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Immunology (AREA)
  • Medicinal Chemistry (AREA)
  • Microbiology (AREA)
  • Mycology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)

Abstract

This invention relates to antigenic compositions that include an ALP3 polypeptide in combination with a polysaccharide such as a group B streptococcus polysaccharide and to methods of using the compositions to elicit an immune response.
PCT/US2007/074985 2006-08-01 2007-08-01 Polysaccharide vaccine and uses thereof Ceased WO2008016984A2 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US83500306P 2006-08-01 2006-08-01
US60/835,003 2006-08-01

Publications (2)

Publication Number Publication Date
WO2008016984A2 WO2008016984A2 (en) 2008-02-07
WO2008016984A3 true WO2008016984A3 (en) 2008-11-20

Family

ID=38997841

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/US2007/074985 Ceased WO2008016984A2 (en) 2006-08-01 2007-08-01 Polysaccharide vaccine and uses thereof

Country Status (1)

Country Link
WO (1) WO2008016984A2 (en)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
RU2757426C2 (en) 2015-10-21 2021-10-15 МинерваКС Апс Immunogenic fused protein
WO2017114655A1 (en) 2015-12-30 2017-07-06 Minervax Aps Immunogenic complex for eliciting protective immunity against group b streptococcus

Non-Patent Citations (5)

* Cited by examiner, † Cited by third party
Title
LACHENAUER ET AL.: "A Protective Surface Protein from Type V Group B Streptococci Shares N-Terminal Sequence Homology with the Alpha C Protein", INFECTION AND IMMUNITY, vol. 64, no. 10, October 1996 (1996-10-01), pages 4255 - 4260 *
LACHENAUER ET AL.: "Mosaicism in the Alpha-Like Protein Genes of Group B Streptococci", PNAS, vol. 97, no. 17, 15 August 2000 (2000-08-15), pages 9630 - 9635, XP002152238, DOI: doi:10.1073/pnas.97.17.9630 *
MAELAND ET AL.: "Antigenic Determinants of Alpha-Like Proteins of the Streptococcus agalactiae", CLINICAL AND DIAGNOSTIC LABORATORY IMMUNOLOGY, vol. 11, no. 6, November 2004 (2004-11-01), pages 1035 - 1039 *
PAOLETTI ET AL.: "Group B Streptococcus Type II Polysaccharide-Tetanus Toxois Conjugate Vaccine", INFECTION AND IMMUNITY, vol. 60, no. 10, October 1992 (1992-10-01), pages 4009 - 4014, XP000601510 *
WESSELS ET AL.: "Immunogenicity in Animals of a Polysaccharide-Protein Conjugate Vaccine against Ype III Group B Streptococcus", J. CLIN. INVEST., vol. 86, November 1990 (1990-11-01), pages 1428 - 1433, XP002546281 *

Also Published As

Publication number Publication date
WO2008016984A2 (en) 2008-02-07

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