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WO2008016666A3 - Entités chimiques, compositions et méthodes - Google Patents

Entités chimiques, compositions et méthodes Download PDF

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Publication number
WO2008016666A3
WO2008016666A3 PCT/US2007/017231 US2007017231W WO2008016666A3 WO 2008016666 A3 WO2008016666 A3 WO 2008016666A3 US 2007017231 W US2007017231 W US 2007017231W WO 2008016666 A3 WO2008016666 A3 WO 2008016666A3
Authority
WO
WIPO (PCT)
Prior art keywords
methods
chemical entities
compositions
certain chemical
muscle myosin
Prior art date
Application number
PCT/US2007/017231
Other languages
English (en)
Other versions
WO2008016666A2 (fr
Inventor
Xiangping Qian
Jeffrey T Finer
Pu-Ping Lu
Chihyuan Grace Chuang
Bradley P Morgan
David J Morgans Jr
Original Assignee
Cytokinetics Inc
Xiangping Qian
Jeffrey T Finer
Pu-Ping Lu
Chihyuan Grace Chuang
Bradley P Morgan
David J Morgans Jr
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Cytokinetics Inc, Xiangping Qian, Jeffrey T Finer, Pu-Ping Lu, Chihyuan Grace Chuang, Bradley P Morgan, David J Morgans Jr filed Critical Cytokinetics Inc
Publication of WO2008016666A2 publication Critical patent/WO2008016666A2/fr
Publication of WO2008016666A3 publication Critical patent/WO2008016666A3/fr

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D239/00—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
    • C07D239/70—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings condensed with carbocyclic rings or ring systems
    • C07D239/72—Quinazolines; Hydrogenated quinazolines
    • C07D239/86—Quinazolines; Hydrogenated quinazolines with hetero atoms directly attached in position 4
    • C07D239/88—Oxygen atoms

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)

Abstract

L'invention concerne des entités chimiques qui modulent la myosine des muscles lisses et/ou la myosine non musculaire, des compositions pharmaceutiques et des méthodes de traitement de pathologies et de troubles associés à la myosine des muscles lisses et/ou à la myosine non musculaire.
PCT/US2007/017231 2006-08-02 2007-08-01 Entités chimiques, compositions et méthodes WO2008016666A2 (fr)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US83523706P 2006-08-02 2006-08-02
US60/835,237 2006-08-02

Publications (2)

Publication Number Publication Date
WO2008016666A2 WO2008016666A2 (fr) 2008-02-07
WO2008016666A3 true WO2008016666A3 (fr) 2008-07-24

Family

ID=38997710

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/US2007/017231 WO2008016666A2 (fr) 2006-08-02 2007-08-01 Entités chimiques, compositions et méthodes

Country Status (1)

Country Link
WO (1) WO2008016666A2 (fr)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
NZ600238A (en) * 2008-06-19 2014-04-30 Takeda Pharmaceutical Heterocyclic compound and use thereof
KR102496364B1 (ko) * 2014-09-10 2023-02-06 에피자임, 인코포레이티드 Ｓｍｙｄ 억제제
EP3876939A4 (fr) 2018-11-07 2022-08-10 Dana-Farber Cancer Institute, Inc. Dérivés benzothiazoles et dérivés 7-aza benzothiazoles comme inhibiteurs de la janus kinase 2 et leurs utilisations
MX2022006700A (es) 2019-12-02 2022-09-02 Storm Therapeutics Ltd Compuestos poliheterociclicos como inhibidores de mettl3.
JP2023525047A (ja) 2020-05-06 2023-06-14 エイジャックス セラピューティクス， インコーポレイテッド Ｊａｋ２阻害薬としての６－ヘテロアリールオキシベンゾイミダゾール及びアザベンゾイミダゾール
WO2022140527A1 (fr) 2020-12-23 2022-06-30 Ajax Therapeutics, Inc. 6-hétéroaryloxy benzimidazoles et azabenzimidazoles utilisés en tant qu'inhibiteurs de jak2
US12162881B2 (en) 2021-11-09 2024-12-10 Ajax Therapeutics, Inc. Forms and compositions of inhibitors of JAK2
EP4430042A1 (fr) 2021-11-09 2024-09-18 Ajax Therapeutics, Inc. 6-hetero-aryloxy-benzimidazoles et azabenzimidazoles en tant qu'inhibiteurs de jak2

Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20070135435A1 (en) * 2005-11-02 2007-06-14 Xiangping Qian Certain chemical entities, compositions, and methods
US20070293530A1 (en) * 2006-06-14 2007-12-20 Methylgene Inc. Sulfamide and sulfamate derivatives as histone deacetylase inhibitors

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20070135435A1 (en) * 2005-11-02 2007-06-14 Xiangping Qian Certain chemical entities, compositions, and methods
US20070293530A1 (en) * 2006-06-14 2007-12-20 Methylgene Inc. Sulfamide and sulfamate derivatives as histone deacetylase inhibitors

Also Published As

Publication number Publication date
WO2008016666A2 (fr) 2008-02-07

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