[go: up one dir, main page]

WO2008007674A1 - Dispositif de chargement d'un produit chimique liquide - Google Patents

Dispositif de chargement d'un produit chimique liquide Download PDF

Info

Publication number
WO2008007674A1
WO2008007674A1 PCT/JP2007/063750 JP2007063750W WO2008007674A1 WO 2008007674 A1 WO2008007674 A1 WO 2008007674A1 JP 2007063750 W JP2007063750 W JP 2007063750W WO 2008007674 A1 WO2008007674 A1 WO 2008007674A1
Authority
WO
WIPO (PCT)
Prior art keywords
cylinder
holder
piston
chemical
chemical liquid
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Ceased
Application number
PCT/JP2007/063750
Other languages
English (en)
Japanese (ja)
Inventor
Shigeru Nemoto
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Nemoto Kyorindo Co Ltd
Original Assignee
Nemoto Kyorindo Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Nemoto Kyorindo Co Ltd filed Critical Nemoto Kyorindo Co Ltd
Priority to JP2008524805A priority Critical patent/JPWO2008007674A1/ja
Publication of WO2008007674A1 publication Critical patent/WO2008007674A1/fr
Anticipated expiration legal-status Critical
Ceased legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/178—Syringes
    • A61M5/1782—Devices aiding filling of syringes in situ
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/14—Infusion devices, e.g. infusing by gravity; Blood infusion; Accessories therefor
    • A61M5/142—Pressure infusion, e.g. using pumps
    • A61M5/145—Pressure infusion, e.g. using pumps using pressurised reservoirs, e.g. pressurised by means of pistons
    • A61M5/1452—Pressure infusion, e.g. using pumps using pressurised reservoirs, e.g. pressurised by means of pistons pressurised by means of pistons
    • A61M5/1456—Pressure infusion, e.g. using pumps using pressurised reservoirs, e.g. pressurised by means of pistons pressurised by means of pistons with a replaceable reservoir comprising a piston rod to be moved into the reservoir, e.g. the piston rod is part of the removable reservoir
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B65—CONVEYING; PACKING; STORING; HANDLING THIN OR FILAMENTARY MATERIAL
    • B65B—MACHINES, APPARATUS OR DEVICES FOR, OR METHODS OF, PACKAGING ARTICLES OR MATERIALS; UNPACKING
    • B65B3/00—Packaging plastic material, semiliquids, liquids or mixed solids and liquids, in individual containers or receptacles, e.g. bags, sacks, boxes, cartons, cans, or jars
    • B65B3/003—Filling medical containers such as ampoules, vials, syringes or the like
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M2209/00—Ancillary equipment
    • A61M2209/04—Tools for specific apparatus
    • A61M2209/045—Tools for specific apparatus for filling, e.g. for filling reservoirs
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/007—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests for contrast media
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/14—Infusion devices, e.g. infusing by gravity; Blood infusion; Accessories therefor
    • A61M5/142—Pressure infusion, e.g. using pumps
    • A61M5/145—Pressure infusion, e.g. using pumps using pressurised reservoirs, e.g. pressurised by means of pistons
    • A61M5/1452—Pressure infusion, e.g. using pumps using pressurised reservoirs, e.g. pressurised by means of pistons pressurised by means of pistons
    • A61M5/1458—Means for capture of the plunger flange

Definitions

  • the present invention relates to a chemical liquid filling device that fills a chemical liquid into a chemical liquid syringe.
  • Medical syringes are widely used in the medical field.
  • CT Computer Tomography
  • MRI Magnetic resonance Imaging
  • diagnostic imaging equipment such as Resonance Imaging, PE ⁇ (Positron mission Tomography), Nonki, and MRA (MR Angio)
  • medical solutions such as contrast media and physiological saline are injected into the subject.
  • a syringe is used.
  • Patent Document 1 and Patent Document 2 disclose a chemical liquid filling device that automatically fills a chemical liquid syringe.
  • the chemical liquid filling device disclosed in Patent Document 1 includes a cylinder holder that holds the cylinder of the chemical liquid syringe, a drive mechanism that moves the piston holder relative to the cylinder holder, and a piston that is held
  • the chemical solution filling device calculates the amount of the necessary chemical solution based on the input inspection condition, and moves the piston according to the calculated amount of the chemical solution.
  • Patent Document 2 describes that a chemical liquid filling device acquires data related to a chemical liquid and data related to a syringe and fills the chemical liquid into the chemical liquid syringe based on these data.
  • the chemical solution filling apparatus has a concave portion that holds a cylinder of the chemical solution syringe and a rod that holds a piston of the chemical solution syringe, and the chemical solution can be filled with the chemical solution by sliding the rod.
  • Patent Document 1 Japanese Patent Application Laid-Open No. 2000-189515
  • Patent Document 2 Japanese Patent Application Laid-Open No. 2004-313579 Disclosure of the invention
  • the conventional chemical liquid filling device holds the chemical liquid syringe by separately holding the cylinder and the piston, and filling the chemical liquid by relatively moving the cylinder and the piston.
  • there are a plurality of types of force chemical syringes for example, for 100 ml and 200 ml, respectively, and there are many cases in which the outer diameters of the cylinder and its flange are different depending on the capacity.
  • the conventional chemical solution filling device only supports one type of outer diameter to hold the cylinder! /, !!, so when you want to fill multiple types of chemical solution syringes, It was necessary to prepare a chemical filling device for each type.
  • Patent Document 2 describes that an adapter used in a chemical liquid injection device can be attached to the chemical liquid filling apparatus, and a chemical liquid with a small outer diameter is provided. It describes that the syringe can be attached to the chemical liquid filling device via an adapter.
  • the adapter used in the chemical injection device is a substantially semi-cylindrical member that holds the outer peripheral portion of the cylinder and the flange on the inner surface. Therefore, the size of the adapter itself is relatively large. Therefore, it is necessary for the chemical filling device to be able to attach such an adapter.
  • the conventional chemical solution filling apparatus fills the chemical solution into the chemical solution syringe by a predetermined amount or an amount obtained from the input data. For this reason, there are also requests for manually setting the filling amount of the chemical solution.
  • a first object of the present invention is to provide a chemical liquid filling device that can be miniaturized while having a configuration capable of filling a plurality of types of chemical liquid syringes having different diameters.
  • the second object of the present invention is to provide a chemical liquid filling device capable of arbitrarily setting the filling amount of the chemical liquid.
  • a chemical liquid filling device of the present invention is a chemical liquid filling device that fills a chemical liquid syringe with a chemical liquid syringe having a cylinder and a piston movably provided in the cylinder, the cylinder holder supporting the cylinder, and the cylinder holder And a piston pull-out mechanism for pulling out the piston of the chemical syringe with the cylinder supported from the cylinder.
  • the cylinder holder is It has a plurality of cylinder flange support portions that support a plurality of cylinders with different diameters and each support a cylinder flange provided in the cylinder.
  • the cylinder holder since the cylinder holder has a plurality of cylinder flange support portions, a plurality of types of chemical liquid syringes having different cylinder diameters can be exchangeably mounted.
  • the cylinder holder supports the cylinder flange, not the outer peripheral surface of the cylinder, so the size can be minimized.
  • examples of the cylinder holder include the following modes.
  • a pair of flange support arm portions that are one of a plurality of cylinder flange support portions that support the cylinder flange of the cylinder having the largest diameter among the plurality of types of cylinders, and the flange
  • at least one adapter provided with a cylinder flange support that is detachably provided on the support arm and is suitable for a cylinder other than the cylinder having the largest diameter among the plurality of types of cylinders.
  • a pair of flange support arm portions that are one of a plurality of cylinder flange support portions that support the cylinder flange of the cylinder having the largest diameter among the plurality of types of cylinders, and the flange
  • an adapter having a plurality of cylinder flange support portions, which are detachably provided on the support arm portion and have the largest diameter among the plurality of types of cylinders! And are adapted to a plurality of types of cylinders other than the cylinders.
  • the cylinder holder is formed with a plurality of cylinder flange support portions in a step shape.
  • the piston pull-out mechanism has a piston holder that holds the piston flange of the piston and pulls the piston out of the cylinder by moving with respect to the cylinder holder. It is preferable to further include a filling amount setting section that includes an operation section that can be adjusted in a direction parallel to the movement direction of the piston holder, and that stops the movement of the piston holder at a position corresponding to the position of the operation section. According to this, the position of the operation unit is adjusted according to the amount of the chemical liquid to be filled, and the filling amount of the chemical liquid into the chemical syringe is set.
  • the filling amount setting unit further includes a holder detection sensor for detecting the piston holder.
  • the movement of the piston holder can be stopped when the piston holder is detected by the holder detection sensor.
  • the cylinder holder is configured as described above, so that the chemical liquid can be filled into a plurality of types of chemical liquid syringes having different cylinder diameters.
  • the structure for holding, and the entire chemical filling device can be downsized.
  • by providing a filling amount setting unit it is possible to arbitrarily set the filling amount of the chemical solution.
  • FIG. 1 is a perspective view of a chemical liquid filling device according to a first embodiment of the present invention.
  • FIG. 2 is a perspective view of a state in which the first chemical liquid syringe is attached to the chemical liquid filling apparatus shown in FIG. 1.
  • FIG. 3 is a perspective view of a state in which the second chemical liquid syringe is attached to the chemical liquid filling apparatus shown in FIG. A certain garden 44]]
  • Fig. 11 shows that the pipistonton holdorda is taken out from the housing of the filling device for chemical liquid filling.
  • FIG. 2 is a perspective view shown in FIG. .
  • FIG. 5 is a diagram schematically showing a filling amount setting / setting part. .
  • FIG. 16 is a plan view of the filling / filling amount setting setting unit shown in FIG. .
  • FIG. 16 is a side view of the side of the filling / filling amount setting setting unit shown in FIG. .
  • FIG. 77AA Another example of the filling and filling amount setting and setting portion is shown, of the fixed and fixed portion to the guide shaft. It is a plane top view figure. .
  • FIG. 77BB Side side surface of the filling and filling amount setting and setting portion shown in FIG. 77AA corresponding to the portion corresponding to FIG. 77AA FIG. .
  • FIG. 2 is a plan view of a part. .
  • FIG. 99 is a plan view of a Sicilinda Dakhoruda that is used in the twenty-second embodiment of the present invention. The .
  • FIG. 99B is a diagram showing a state where the eleventh drug solution Sicilinundisi's sicilinunda is supported and supported by 99BB.
  • FIG. 9B is a diagram showing a state where the second chemical solution, ⁇ , is supported.
  • FIG. 1 is a perspective view of a chemical liquid filling device according to a first embodiment of the present invention.
  • Figure 2 FIG. 3 is a perspective view of a state in which the first chemical liquid syringe is attached to the chemical liquid filling apparatus shown in FIG. 1, and
  • FIG. 3 is a perspective view of a state in which the second chemical liquid syringe is attached to the chemical liquid filling apparatus shown in FIG.
  • the chemical liquid filling device 100 of the present embodiment has either the first chemical liquid syringe 200 shown in FIG. 2 or the second chemical liquid syringe 210 shown in FIG. Alternatively, the first or second chemical liquid syringe 200, 210 is filled with the chemical liquid by operating the second chemical liquid syringe 200, 210.
  • the medicine night syringes 200, 210 have a cylinder 201, 211, and a piston 202, 212 inserted into the cylinder 201, 211 so as to be reciprocally movable in the direction of the vehicle.
  • Cylinder 200, 210 (with one end of the cylinder, 201b, 21 lb, and lower.
  • Piston 202, 212 (The other end, which is the end opposite to one end of the cylinder 201, 211) Are inserted into cylinders 201 and 211.
  • Cylinder flanges 201a and 211a are formed at the other ends of the cylinders 201 and 211.
  • the pistons 202 and 212 are also connected to the cylinders 201 and 211.
  • Piston flanges 202a and 212a are formed at the end opposite to the inserted flange J.
  • the capacity of the first chemical liquid syringe 200 is larger than the capacity of the second chemical liquid syringe 210.
  • the volume of the first chemical syringe 200 is 200 ml
  • the volume of the second chemical syringe 210 is 100 ml. Therefore, when the first chemical syringe 200 and the second chemical syringe 210 are compared, the size of the first chemical syringe 200 is larger than that of the second chemical syringe 210.
  • the diameter is larger than the diameters of the cylinder 211 and the cylinder flange 211a of the second chemical liquid syringe 210.
  • the strokes of the pistons 202 and 212 are the same for both the first chemical liquid syringe 200 and the second chemical liquid syringe 210.
  • the strokes of the pistons 202 and 212 may be different between the first chemical syringe 200 and the second chemical syringe 210.
  • the chemical liquid filling device 100 includes a cylinder holder 110, and a piston honoreda 120 that is disposed so as to face the cylinder holder 110 and supported to move toward and away from the cylinder holder 110. .
  • the direction in which the cylinder hore 110 and the piston hore 120 are opposed to each other is not particularly limited, but in the present embodiment, the chemical liquid filling device 100 is used. Both are arranged so that the piston holder 120 is located below the cylinder holder 110 in the service state.
  • the cylinder holder 110 includes two flange support arms 111 fixed to the housing 101, and an adapter 150 that is detachably attached to the flange support arm 111.
  • the flange support arm 111 supports the cylinder flange 201a of the first drug solution syringe 200, and is arranged in parallel at intervals in the direction orthogonal to the moving direction of the piston holder 120.
  • the upper surfaces of these flange support arms 111 (the surface opposite to the surface facing the piston holder 120) serve as a mounting surface 11la on which the cylinder flange 201a is mounted.
  • a cylinder flange 201a is mounted on the mounting surface 111a with the conduit portion 201b facing upward, whereby the cylinder 201 of the first chemical syringe 200 is mounted on the cylinder holder. Supported on 110.
  • the piston 202 of the first chemical syringe 200 extends from between the two flange support portions 111 toward the piston holder 120, and is filled between the two flange support portions 111 when filling the chemical solution.
  • the movement of the piston 202 is accompanied. For this reason, the distance between the two flange support arms 111 does not interfere with the flange support arm 111 even if the piston 202 moves!
  • the adapter 150 is for allowing the second chemical syringe 210 to be attached in place of the first chemical syringe 200, and includes two adapters into which the flange support arms 111 of the cylinder holder 110 are inserted. There are fitting grooves 153 on both sides. By inserting the flange support arm 111 into these fitting grooves 153, the adapter 150 is detachably attached to the cylinder holder 110. A recess 151 for receiving the piston 212 of the second chemical syringe 2 10 from the side is formed between the fitting grooves 153 of the adapter 150, and the adapter 150 is formed in a substantially U shape as a whole! /
  • the recess 151 is located on the side farther from the piston holder 120 force than the side closer to the piston holder 120.
  • a flange support portion 152 protruding toward the center of the recess is formed in a step shape on the inner peripheral surface of the adapter 140 forming the recess 151.
  • the flange support portion 152 is configured so that the cylinder flange 21 of the second drug solution syringe 210 is placed with the conduit portion 21 lb facing upward. By placing la, the cylinder 211 is supported.
  • the piston holder 120 has a hono-redder main body 121 and a slider portion 122 provided integrally with the holder main body 121, together with piston holder driving means for driving the piston holder 120.
  • the piston pulling mechanism is configured.
  • the slider section 122 constitutes a part of a ball screw mechanism that is a piston holder driving means.
  • the ball screw mechanism includes a ball screw shaft 132 disposed in parallel to a direction in which the flange support arm 111 (see FIG. 1) and the piston holder 120 face each other, and a ball screw nut that is screwed onto the ball screw shaft 132.
  • the slider 122 functions as this ball screw nut. Further, in order to prevent the slider portion 122 from rotating, a guide shaft 131 arranged in parallel with the ball screw shaft 132 passes through the slider portion 122.
  • the slider portion 122, the guide shaft 131, and the ball screw shaft 132 are accommodated in a housing 101 (see FIG. 1) of the chemical liquid filling device 100.
  • the holder main body 121 extends out of the housing 101, and has a flange support arm.
  • the holder main body 121 has two flange presser arms 121a arranged in the same manner as the flange support arm 111.
  • the distance between the two flange presser arms 121a is larger than the diameter of the piston 202 and smaller than the diameter of the piston flange 202a.
  • a stepping motor (not shown) can be used as a driving source for the ball screw shaft 132.
  • the cylinder flange 201a is supported on the flange support arm 111 and the piston flange 202a is held by the piston holder 120, whereby the first chemical liquid syringe. 200 is installed (see Figure 2). Also, the cylinder flange 21 la is supported on the adapter 150, and the piston holder 120 By holding the screw 212a, the second chemical syringe 210 is attached (see FIG. 3).
  • the adapter 211 as described above corresponds to the cylinder 211 of the second chemical syringe 210, but such an adapter is not necessary for the piston 212.
  • a chemical solution is injected into a subject using a chemical solution injection device (not shown)
  • the chemical solution injection device pushes the piston into the cylinder with the piston flange chucked. Since the rod portion and flange of the piston can be designed regardless of the capacity of the chemical syringe, in general, the dimensions of the piston flange are often common regardless of the capacity of the chemical syringe. Therefore, also in the chemical liquid filling apparatus 100 of the present embodiment, the piston holder 120 can be used in common for the chemical liquid syringes 200 and 210.
  • the chemical filling apparatus 100 of this embodiment sets an initialization sensor for setting the initial position of the piston holder 120, a syringe detection sensor for detecting the mounting of the chemical syringes 200 and 210, and a filling amount of the chemical liquid And a filling amount setting unit.
  • Each of these sensors and the filling amount setting unit are built in the housing 101.
  • the initialization sensor 131 has a limit switch 132.
  • This limit switch 132 has a lever type actuator.
  • the slider 122 is brought into contact with the limit switch 132 (indicated by a broken line in the figure), and the limit switch 132 is It is arranged at the position to turn on.
  • the limit switch 132 is turned on, it is detected that the piston holder 120 is in the initial position.
  • the syringe detection sensor 136 is positioned above the cylinder holder 110, and includes a limit switch 137 and a rod 138 that is slidably supported.
  • the rod 138 is provided with a tip protruding from the side surface of the housing 101 at a position facing the outer peripheral surface of the cylinder when the chemical syringe is supported by the cylinder holder 110. Is biased in a direction protruding from the side surface of the housing 101.
  • the limit switch 137 has a lever type actuator that is displaced when the rod 138 is pushed into the housing 101.
  • the syringe detection sensor 136 is not equipped with a chemical syringe in the chemical filling device 100. It is off in the state.
  • the rod 138 is pushed into the housing 101 by the cylinder of the attached chemical syringe.
  • the pushed rod 138 displaces the actuator of the limit switch 137, whereby the syringe detection sensor 136 is turned on.
  • the syringe detection sensor 136 is turned on, it is detected that the chemical syringe is attached to the chemical filling device 100.
  • the drug solution syringes to be detected by the syringe detection sensor 136 are both the first and second drug solution syringes 200 and 210, but only the first drug solution syringe 200 having a large diameter is used. It may be. Also, as the output at the time of detection, a sensor that takes a plurality of states according to the displacement of the actuator rather than simple on / off is used, and either the first chemical syringe 200 or the second chemical syringe 210 is attached. It may be possible to reduce the height by half from the output from the sensor.
  • the above-described initialization sensor 131 and syringe detection sensor 136 are merely examples, and may be any devices that can detect the mounting of the chemical syringe on the chemical liquid filling device 100 and the initialization position of the piston holder 120, respectively. Any detection device such as an optical sensor can be used.
  • the filling amount setting unit 140 is arranged below the piston holder 120, that is, at a position farther from the cylinder holder 110 than the piston holder 120.
  • the filling amount setting unit 140 will be described with reference to FIGS. 6A and 6B.
  • the filling amount setting unit 140 has a first operation lever 141 through which the above-described guide shaft 131 and the ball screw shaft 132 pass, and slidably supported with respect to the guide shaft 131 and the ball screw shaft 132.
  • the first operating lever 141 is provided with a second operating lever 142 that is rotatable around the support shaft 143 by a support shaft 143 arranged in parallel with the guide shaft 131.
  • the support shaft 143 supports the second operation lever 142 at the intermediate portion in the longitudinal direction of the second operation lever 142.
  • One end portions of the first operation lever 141 and the second operation lever 142 are operation knob portions 141a and 142a, respectively.
  • the operation knob portions 141a and 142a are arranged to face each other and extend to the outside of the casing 101 (see FIG. 1).
  • the second operating lever 142 is configured such that the operating knob 142a is moved by the torsion coil spring 144 held by the support shaft 143. Is biased away from the operation knob 141a.
  • the tip of the second operation lever 142 extends to a position facing the guide shaft 131, and a stopper is provided on the surface facing the guide shaft 131.
  • 146 is fixed.
  • the stock 146 is preferably made of a material having a high coefficient of static friction with respect to the guide shaft 131, such as rubber.
  • a holder detection sensor 145 that detects the piston holder 120 is provided at the tip of the first operation lever 141.
  • the holder detection sensor 145 any means such as an optical sensor or a limit switch can be used as long as it can detect the piston holder 120.
  • an optical sensor having a light emitting element and a light receiving element is used as the holoreder detection sensor 145.
  • a shielding plate 122a is provided so as to protrude from the slider portion 122 of the piston holder 120, as shown by a one-dot chain line in FIG. More specifically, the shielding plate 122a extends between the light emitting element and the light receiving element of the holder detection sensor 145 on the side of the slider part 122 facing the filling amount setting part 140.
  • the piston holder 120 is detected by the proximity of the piston holder 120 and the filling amount setting unit 140, and the shielding plate 122a entering between the light emitting element and the light receiving element. The power to do S.
  • the chemical liquid filling operation by the chemical liquid filling apparatus 100 of the present embodiment will be described.
  • the piston holder 120 When power is supplied to the chemical solution filling apparatus 100, the piston holder 120 is moved to an initial position that is a position close to the cylinder holder 110. In this state, the first chemical solution syringe 200 or the second chemical solution syringe 210 is attached to the chemical solution filling apparatus 100. When the chemical syringe 200, 210 is attached, this is detected by the syringe detection sensor 136, and the chemical filling device 100 enters a standby state.
  • the subsequent operation of the chemical solution filling apparatus 100 will be described by taking as an example the case of filling the first chemical solution syringe 200 with the chemical solution.
  • the adapter 150 is not used and the cylinder flange 201a is placed on the flange support arm 111. Since the piston holder 120 is in the initial position, the piston holder 120 is located between the flange support arm 111 and the piston flange 202a.
  • a chemical solution container (not shown) is connected to the conduit portion 201b of the chemical solution syringe 200 via a tube (not shown).
  • the filling amount of the chemical solution into the chemical syringe 200 is set.
  • the filling amount is set by the filling amount setting unit 140.
  • the operator operates the operation knobs 141a and 142a to set the filling amount setting unit 140 to a predetermined position determined according to the filling amount of the chemical solution into the chemical syringe 200.
  • a scale not shown
  • the moving speed of the piston holder 120 at the time of filling the chemical liquid can be appropriately set according to the viscosity of the chemical liquid to be filled.
  • the filling rate of the drug solution is It is preferable to move the piston holder 120 so that it is within the range of 1.0 ml / sec to 3. Oml / sec.
  • the movement speed of the piston holder 120 can be made variable so that the injection speed of the chemical can be adjusted according to the type of chemical!
  • the movement of the piston holder 120 during the filling of the chemical solution is also a movement in a direction approaching the filling amount setting unit 140.
  • the piston holder 120 moves toward the filling amount setting unit 140, and the shielding plate 122a is detected by the holder detection sensor 145 as shown in FIG. 6B, the operation of the piston holder driving mechanism is stopped.
  • the chemical solution syringe 200 is filled with the chemical solution while the piston 202 is pulled out of the cylinder 201. Therefore, when the operation of the piston holder driving mechanism stops, a force in a direction in which the piston 201 is pushed into the cylinder 201 acts on the piston 201 from the relationship between the internal pressure of the cylinder 201 and the atmospheric pressure. Due to this force, the cylinder flange 201a and the piston flange 202a are pressed against the flange support arm 111 and the piston holder 120, respectively, and it may be difficult to remove the chemical liquid syringe 200.
  • the above is the filling operation of the chemical liquid into the first chemical liquid syringe 200.
  • the adapter 150 is attached to the flange support arm 111, and the cylinder flange 21 la is placed on the flange placement surface 152 of the adapter 150, whereby the second chemical solution syringe 2 10 is filled.
  • the chemical solution syringe 210 is attached to the chemical solution filling device 100.
  • the subsequent procedures and operations are the same as those for the first chemical syringe 200.
  • the cylinder holder 110 is attached to the pair of flange support arms 111 that are compatible with the first chemical liquid syringe 200, and the adapter 150 that is compatible with the second chemical liquid syringe 210 is detachably provided.
  • the two types of chemical syringes 200 with different diameters , 210 can be filled with chemicals.
  • the flange support arm 111 supports the cylinder flange 201a, and the adapter 150 is also attached to the flange support arm 111 to support the cylinder flange 212a of the second drug solution syringe 210. It is formed as a part having a stepped recess 151.
  • Both the flange support arm 111 and the adapter 150 do not support the outer peripheral surface of the chemical syringes 200 and 210, but only the cylinder flanges 201a and 21 la, so that they are extremely simple and small in size. be able to.
  • the chemical filling device 100 according to the present embodiment can be significantly reduced in size compared to the conventional chemical filling device, whether viewed with the entire configuration including the adapter 150 or with the adapter 150 alone. .
  • the chemical liquid filling device 100 of the present embodiment has a filling amount setting unit 140 for stopping the movement of the piston holder 120, and the position of the filling amount setting unit 140 is provided to be adjustable.
  • the filling amount of the chemical solution can be arbitrarily set.
  • the first operation lever 141 and the piston holder 120 of the filling amount setting unit 140 are supported by a common support member (in this embodiment, the guide shaft 131 and the ball screw shaft 132), so that a new amount for the filling amount setting unit 140 can be obtained. No support member is required.
  • the structure is simplified, and an increase in the size of the chemical liquid filling device 100 due to the provision of the filling amount setting unit 140 can be minimized.
  • the filling amount setting unit 140 has shown an example in which the filling amount setting unit 140 is fixed at an arbitrary position by using the static frictional force between the guide shaft 131 and the stagger 146.
  • the structure for fixing the quantity setting unit 140 is not limited to this.
  • the mating hook 147 extends from the front end portion of the second operation lever 142 toward the guide shaft 131 by force.
  • a rack 131b is provided in a region of the guide shaft 131 facing the meshing hook 147.
  • Rack 131a The id shaft 131 has a large number of teeth arranged in the axial direction.
  • the positioning pin 148 extends from the front end portion of the second operation lever 142 toward the guide shaft 131.
  • a plurality of positioning holes 131b are provided at regular intervals along the axial direction of the guide shaft 131 in a region facing the positioning pin 148 of the guide shaft 131.
  • the positioning pin 148 engages with the positioning hole 131b, thereby filling the filling amount.
  • the position of the setting unit is fixed.
  • the filling amount setting portion can be moved along the guide shaft 131.
  • the position of the filling amount setting portion with respect to the guide shaft 131 can be adjusted by changing the positioning hole 131b with which the positioning pin 148 is engaged.
  • the chemical liquid filling apparatus including the filling amount setting unit has been described on the assumption that the filling amount of the chemical liquid can be arbitrarily set.
  • the movement amount of the piston holder 120 is determined in advance, and the chemical liquid can be filled by a predetermined amount. In that case, the filling amount setting unit is unnecessary.
  • the force shown in the example in which the adapter 150 is detachably provided so that the two types of chemical syringes 200 and 210 having different diameters can be filled with the chemical solution is compatible with the chemical syringes having different diameters.
  • two types with different diameters are used by using an adapter for a cylinder holder.
  • a chemical solution filling apparatus that can fill a chemical solution syringe with a chemical solution has been described.
  • an example of a chemical filling apparatus capable of filling two types of chemical liquid syringes having different diameters by using a cylinder holder in a specific shape without using an adapter will be described.
  • FIG. 9A shows a plan view of the cylinder holder 160 used in the second embodiment of the present invention.
  • FIG. 9B is a front view of the cylinder holder 160. Since the configuration other than the cylinder holder 160 in the chemical liquid filling device of the present embodiment may be the same as that of the first embodiment, the description thereof is omitted, and not only FIG. 9A and FIG. 9B but also the first embodiment.
  • the cylinder holder 160 of this embodiment will be described with reference to the drawings used in the description.
  • the cylinder holder 160 is configured by a generally plate-like member, and can be provided integrally with the housing of the chemical liquid filling apparatus, as in the first embodiment.
  • the cylinder holder 160 has a recess 162 partially opened so that the pistons 201 and 211 (see FIGS. 2 and 3) of the chemical syringes 200 and 210 can be received from the side. It is formed to penetrate in the direction.
  • first and second flange support portions 163, 164 are formed stepwise.
  • the second flange support portion 164 supports the cylinder flange 21 la of the second drug solution syringe 210, and is formed around the recess 162 as a first step.
  • the first flange support portion 163 supports the cylinder flange 201a of the first chemical syringe 200, and is formed around the second flange support portion 164 as a second step.
  • the cylinder holder 160 has the two flange support portions 163 and 164 provided in a stepped manner, so that two types of drug solution syringes having different diameters without using an adapter are used. Can be filled. Also, by not using an adapter, the number of parts can be reduced and the adapter can be lost.
  • the cylinder holder can be configured by having three or more flange support portions provided in a step shape. According to this, it is possible to deal with three or more types of chemical syringes having different diameters.
  • the first embodiment and the second embodiment are combined 3 It is possible to correspond to more than one kind of liquid syringe.
  • an adapter 170 mounted on a flange support arm 111 similar to that shown in FIG. 1 has a structure having two flange support portions 171 and 172 provided in a step shape. To do.
  • one type of chemical liquid syringe supported by the flange support arm 111 and two types of chemical liquid syringes supported by the adapter 170 can be used in combination with three types of chemical liquid syringes.
  • the flange support arm 111 is supported by the chemical syringe having the largest cylinder diameter among the three types of chemical syringes.
  • the number of stages of the flange support part of the adapter 170 is three or more, it is possible to handle four or more types of liquid syringes.

Landscapes

  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Vascular Medicine (AREA)
  • Anesthesiology (AREA)
  • Biomedical Technology (AREA)
  • Hematology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Mechanical Engineering (AREA)
  • Infusion, Injection, And Reservoir Apparatuses (AREA)
  • Medical Preparation Storing Or Oral Administration Devices (AREA)

Abstract

Dispositif de chargement d'un produit chimique liquide (100) ayant un support de cylindre (110) et un support de piston (120). Le support de cylindre (110) a un bras support à bride (111) et un adaptateur (150) attaché de façon détachable au bras support à bride (111). Le bras support à bride (111) supporte une seringue de produit chimique liquide au niveau sa bride de cylindre et cette seringue est une seringue ayant un cylindre ayant le diamètre maximal parmi les cylindres de seringues de produit chimique liquide, remplie d'un produit chimique liquide par le dispositif de chargement de produit chimique liquide (100). L'adaptateur (150) a une section de support de bride (152) servant à supporter la bride de cylindre d'une seringue de produit chimique liquide dont le cylindre a un plus petit diamètre que le cylindre ayant le diamètre maximal.
PCT/JP2007/063750 2006-07-11 2007-07-10 Dispositif de chargement d'un produit chimique liquide Ceased WO2008007674A1 (fr)

Priority Applications (1)

Application Number Priority Date Filing Date Title
JP2008524805A JPWO2008007674A1 (ja) 2006-07-11 2007-07-10 薬液充填装置

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
JP2006-190816 2006-07-11
JP2006190816 2006-07-11

Publications (1)

Publication Number Publication Date
WO2008007674A1 true WO2008007674A1 (fr) 2008-01-17

Family

ID=38923231

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/JP2007/063750 Ceased WO2008007674A1 (fr) 2006-07-11 2007-07-10 Dispositif de chargement d'un produit chimique liquide

Country Status (2)

Country Link
JP (1) JPWO2008007674A1 (fr)
WO (1) WO2008007674A1 (fr)

Cited By (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2009183469A (ja) * 2008-02-06 2009-08-20 Nippon Pulse Motor Co Ltd シリンダユニット
WO2011145464A1 (fr) * 2010-05-20 2011-11-24 株式会社根本杏林堂 Tête d'injection et système d'injection de solution de médicament
WO2012066767A1 (fr) * 2010-11-18 2012-05-24 パナソニック株式会社 Dispositif d'injection de médicament
WO2014129493A1 (fr) * 2013-02-20 2014-08-28 株式会社根本杏林堂 Dispositif d'aspiration de solution chimique actionné mécaniquement
JP2014168601A (ja) * 2013-03-05 2014-09-18 Mita Rika Kogyo Kk シリンジ充填装置
JP2015139625A (ja) * 2014-01-30 2015-08-03 テルモ株式会社 薬液充填装置
JP2016116908A (ja) * 2016-02-17 2016-06-30 アッヴィ合同会社 自己注射補助具および自己注射システム
JP2017035358A (ja) * 2015-08-11 2017-02-16 株式会社安川電機 薬品搾取方法及び薬品搾取システム
ES2643119A1 (es) * 2016-05-18 2017-11-21 Kiro Grifols S.L Dispositivo para la carga de contenedores médicos en máquinas de dosificación, adaptador para los contenedores, soporte para los adaptadores y usos de los mismos
JP2018019671A (ja) * 2016-08-05 2018-02-08 パナソニック株式会社 液体移動装置
JP2019013780A (ja) * 2013-08-02 2019-01-31 ジェイ アンド ジェイ ソリューションズ，インコーポレイテッド 薬の安全な移送のための配合システムおよび方法
JP2021090628A (ja) * 2019-12-10 2021-06-17 ピジョン株式会社 採乳補助具および採乳装置
WO2023037163A1 (fr) * 2021-09-10 2023-03-16 Takeda Pharmaceutical Company, Limited Pompe à perfusion

Citations (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS58112551A (ja) * 1981-12-21 1983-07-05 ビー・ブラウン―エスエスシー・アクチエンゲゼルシャフト 医療用加圧点滴装置
JPH01166768A (ja) * 1987-11-22 1989-06-30 Fresenius Ag 注入ポンプ
JP2000513261A (ja) * 1996-07-01 2000-10-10 フアーマシア・アンド・アツプジヨン・アー・ベー 注入装置およびその操作方法
JP2004313579A (ja) * 2003-04-18 2004-11-11 Nemoto Kyorindo:Kk 薬液充填装置
JP2005021431A (ja) * 2003-07-03 2005-01-27 Nemoto Kyorindo:Kk 薬液注入システム
WO2006057089A1 (fr) * 2004-11-26 2006-06-01 Nemoto Kyorindo Co., Ltd Systeme d’injection de fluides medicaux

Patent Citations (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS58112551A (ja) * 1981-12-21 1983-07-05 ビー・ブラウン―エスエスシー・アクチエンゲゼルシャフト 医療用加圧点滴装置
JPH01166768A (ja) * 1987-11-22 1989-06-30 Fresenius Ag 注入ポンプ
JP2000513261A (ja) * 1996-07-01 2000-10-10 フアーマシア・アンド・アツプジヨン・アー・ベー 注入装置およびその操作方法
JP2004313579A (ja) * 2003-04-18 2004-11-11 Nemoto Kyorindo:Kk 薬液充填装置
JP2005021431A (ja) * 2003-07-03 2005-01-27 Nemoto Kyorindo:Kk 薬液注入システム
WO2006057089A1 (fr) * 2004-11-26 2006-06-01 Nemoto Kyorindo Co., Ltd Systeme d’injection de fluides medicaux

Cited By (21)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2009183469A (ja) * 2008-02-06 2009-08-20 Nippon Pulse Motor Co Ltd シリンダユニット
WO2011145464A1 (fr) * 2010-05-20 2011-11-24 株式会社根本杏林堂 Tête d'injection et système d'injection de solution de médicament
JPWO2011145464A1 (ja) * 2010-05-20 2013-07-22 株式会社根本杏林堂 注入ヘッドおよび薬液注入システム
US9446206B2 (en) 2010-11-18 2016-09-20 Panasonic Healthcare Holdings Co., Ltd. Pharmaceutical injection device
WO2012066767A1 (fr) * 2010-11-18 2012-05-24 パナソニック株式会社 Dispositif d'injection de médicament
CN103228304A (zh) * 2010-11-18 2013-07-31 松下电器产业株式会社 药剂注入装置
JPWO2012066767A1 (ja) * 2010-11-18 2014-05-12 パナソニック株式会社 薬剤注入装置
CN103228304B (zh) * 2010-11-18 2015-11-25 松下健康医疗控股株式会社 药剂注入装置
WO2014129493A1 (fr) * 2013-02-20 2014-08-28 株式会社根本杏林堂 Dispositif d'aspiration de solution chimique actionné mécaniquement
JP2014168601A (ja) * 2013-03-05 2014-09-18 Mita Rika Kogyo Kk シリンジ充填装置
JP2019013780A (ja) * 2013-08-02 2019-01-31 ジェイ アンド ジェイ ソリューションズ，インコーポレイテッド 薬の安全な移送のための配合システムおよび方法
JP2015139625A (ja) * 2014-01-30 2015-08-03 テルモ株式会社 薬液充填装置
JP2017035358A (ja) * 2015-08-11 2017-02-16 株式会社安川電機 薬品搾取方法及び薬品搾取システム
JP2016116908A (ja) * 2016-02-17 2016-06-30 アッヴィ合同会社 自己注射補助具および自己注射システム
ES2643119A1 (es) * 2016-05-18 2017-11-21 Kiro Grifols S.L Dispositivo para la carga de contenedores médicos en máquinas de dosificación, adaptador para los contenedores, soporte para los adaptadores y usos de los mismos
US10646403B2 (en) 2016-05-18 2020-05-12 Kiro Grifols, S.L. Device for loading medical containers in dosing machines, adapter for the containers, support for the adapters and use thereof
US11337893B2 (en) 2016-05-18 2022-05-24 Kiro Grifols, S.L. Adaptor for medical containers
JP2018019671A (ja) * 2016-08-05 2018-02-08 パナソニック株式会社 液体移動装置
JP2021090628A (ja) * 2019-12-10 2021-06-17 ピジョン株式会社 採乳補助具および採乳装置
JP7433032B2 (ja) 2019-12-10 2024-02-19 ピジョン株式会社 採乳補助具および採乳装置
WO2023037163A1 (fr) * 2021-09-10 2023-03-16 Takeda Pharmaceutical Company, Limited Pompe à perfusion

Also Published As

Publication number Publication date
JPWO2008007674A1 (ja) 2009-12-10

Similar Documents

Publication Publication Date Title
WO2008007674A1 (fr) Dispositif de chargement d'un produit chimique liquide
US7025757B2 (en) Syringe loading devices for use with syringes and medical injectors
JP4338447B2 (ja) 薬液注入システム
JP4708189B2 (ja) 薬液注入装置への薬液シリンジの着脱を検出する薬液注入システム
JP4256677B2 (ja) 医療用インジェクタに使用されるシリンジインターフェース及びアダプタ
JP4960180B2 (ja) 薬液注入装置及び薬液注入システム
JP5490840B2 (ja) 薬液注入装置及び薬液注入システム
JP4934431B2 (ja) 薬液注入システム
JP2005000203A (ja) 薬液注入システム
JP5346231B2 (ja) シリンジホルダ
JP2024161140A (ja) 薬液注入器およびそれを備えた薬液注入装置
JP4902096B2 (ja) 薬液シリンジ
JP4769196B2 (ja) コントローラ装置
US7192417B2 (en) Injectors and syringe interfaces for syringes of variable size
JP4044780B2 (ja) 注入ヘッド
JP5027888B2 (ja) 薬液注入装置の動作確認装置
JP4394342B2 (ja) 薬液注入システム
JP4198442B2 (ja) 薬液注入装置
JP4594582B2 (ja) 薬液注入装置
JP4154185B2 (ja) 薬液注入システム
JP4119224B2 (ja) 薬液注入装置
JP2008295926A (ja) 応力吸収構造を備えたシリンジ操作装置
JP2024161141A (ja) 薬液注入器およびそれを備えた薬液注入装置
WO2006132146A1 (fr) Adaptateur cylindrique
US20200069868A1 (en) Injector

Legal Events

Date Code Title Description
121 Ep: the epo has been informed by wipo that ep was designated in this application

Ref document number: 07790568

Country of ref document: EP

Kind code of ref document: A1

WWE Wipo information: entry into national phase

Ref document number: 2008524805

Country of ref document: JP

NENP Non-entry into the national phase

Ref country code: DE

NENP Non-entry into the national phase

Ref country code: RU

122 Ep: pct application non-entry in european phase

Ref document number: 07790568

Country of ref document: EP

Kind code of ref document: A1