[go: up one dir, main page]

WO2008005752A3 - Modification of surfaces of polymeric articles by michael addition reaction - Google Patents

Modification of surfaces of polymeric articles by michael addition reaction Download PDF

Info

Publication number
WO2008005752A3
WO2008005752A3 PCT/US2007/072119 US2007072119W WO2008005752A3 WO 2008005752 A3 WO2008005752 A3 WO 2008005752A3 US 2007072119 W US2007072119 W US 2007072119W WO 2008005752 A3 WO2008005752 A3 WO 2008005752A3
Authority
WO
WIPO (PCT)
Prior art keywords
addition reaction
michael addition
medical device
coating polymer
modification
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Ceased
Application number
PCT/US2007/072119
Other languages
French (fr)
Other versions
WO2008005752A2 (en
Inventor
Joseph C Salamone
Wenyan Yan
Yu-Chin Lai
Weihong Lang
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Bausch and Lomb Inc
Original Assignee
Bausch and Lomb Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from US11/480,243 external-priority patent/US20080003259A1/en
Priority claimed from US11/479,227 external-priority patent/US20080003252A1/en
Application filed by Bausch and Lomb Inc filed Critical Bausch and Lomb Inc
Priority to EP07812327A priority Critical patent/EP2035050A2/en
Publication of WO2008005752A2 publication Critical patent/WO2008005752A2/en
Publication of WO2008005752A3 publication Critical patent/WO2008005752A3/en
Anticipated expiration legal-status Critical
Ceased legal-status Critical Current

Links

Classifications

    • G—PHYSICS
    • G02—OPTICS
    • G02B—OPTICAL ELEMENTS, SYSTEMS OR APPARATUS
    • G02B1/00—Optical elements characterised by the material of which they are made; Optical coatings for optical elements
    • G02B1/04—Optical elements characterised by the material of which they are made; Optical coatings for optical elements made of organic materials, e.g. plastics
    • G02B1/041—Lenses
    • G02B1/043—Contact lenses
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/28—Materials for coating prostheses
    • A61L27/34—Macromolecular materials
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2400/00—Materials characterised by their function or physical properties
    • A61L2400/18—Modification of implant surfaces in order to improve biocompatibility, cell growth, fixation of biomolecules, e.g. plasma treatment

Landscapes

  • Health & Medical Sciences (AREA)
  • Physics & Mathematics (AREA)
  • Transplantation (AREA)
  • Epidemiology (AREA)
  • Chemical & Material Sciences (AREA)
  • Dermatology (AREA)
  • Medicinal Chemistry (AREA)
  • Oral & Maxillofacial Surgery (AREA)
  • General Physics & Mathematics (AREA)
  • Optics & Photonics (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Materials For Medical Uses (AREA)

Abstract

A medical device having an increased surface hydrophilicity comprises a coating polymer comprising units of a polymerizable hydrophilic compound that is attached to the surface of the medical device via the Michael addition reaction. The coating polymer can be applied to a medical device comprising a hydrogel material. The attachment of the coating polymer may be enhanced by increasing the population of the medical-device surface functional groups before contacting the medical device with the coating polymer.
PCT/US2007/072119 2006-06-30 2007-06-26 Modification of surfaces of polymeric articles by michael addition reaction Ceased WO2008005752A2 (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
EP07812327A EP2035050A2 (en) 2006-06-30 2007-06-26 Modification of surfaces of polymeric articles by michael addition reaction

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
US11/480,243 US20080003259A1 (en) 2006-06-30 2006-06-30 Modification of surfaces of polymeric articles by Michael addition reaction
US11/479,227 2006-06-30
US11/480,243 2006-06-30
US11/479,227 US20080003252A1 (en) 2006-06-30 2006-06-30 Functionalized hydrophilic macromonomers and medical devices incorporating same

Publications (2)

Publication Number Publication Date
WO2008005752A2 WO2008005752A2 (en) 2008-01-10
WO2008005752A3 true WO2008005752A3 (en) 2008-09-18

Family

ID=38669223

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/US2007/072119 Ceased WO2008005752A2 (en) 2006-06-30 2007-06-26 Modification of surfaces of polymeric articles by michael addition reaction

Country Status (2)

Country Link
EP (1) EP2035050A2 (en)
WO (1) WO2008005752A2 (en)

Families Citing this family (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP2398523B1 (en) * 2009-02-21 2018-04-04 Covidien LP Medical devices having activated surfaces
US9486311B2 (en) 2013-02-14 2016-11-08 Shifamed Holdings, Llc Hydrophilic AIOL with bonding
US9250357B2 (en) 2013-03-15 2016-02-02 Johnson & Johnson Vision Care, Inc. Silicone-containing contact lens having reduced amount of silicon on the surface
BR112015024156A2 (en) 2013-03-21 2017-07-18 Shifamed Holdings Llc accommodation intraocular lens
US10195018B2 (en) 2013-03-21 2019-02-05 Shifamed Holdings, Llc Accommodating intraocular lens
EP4574093A3 (en) 2014-08-26 2025-09-17 Shifamed Holdings, LLC Accommodating intraocular lens
US11141263B2 (en) 2015-11-18 2021-10-12 Shifamed Holdings, Llc Multi-piece accommodating intraocular lens
EP4375066B1 (en) 2015-11-18 2025-07-30 Shifamed Holdings, LLC Multi-piece accommodating intraocular lens
WO2018119408A1 (en) 2016-12-23 2018-06-28 Shifamed Holdings, Llc Multi-piece accommodating intraocular lenses and methods for making and using same
US10350056B2 (en) 2016-12-23 2019-07-16 Shifamed Holdings, Llc Multi-piece accommodating intraocular lenses and methods for making and using same
WO2018222579A1 (en) 2017-05-30 2018-12-06 Shifamed Holdings, Llc Surface treatments for accommodating intraocular lenses and associated methods and devices
CN110996850B (en) 2017-06-07 2023-02-17 施菲姆德控股有限责任公司 Intraocular lens capable of adjusting optical power
US10975246B2 (en) 2018-03-27 2021-04-13 Mercene Coatings Ab Coating and primer
CA3206178A1 (en) * 2020-12-30 2022-07-07 Convatec Technologies Inc. Functionalisation of medical devices

Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2000072052A1 (en) * 1999-05-20 2000-11-30 Bausch & Lomb Incorporated Surface treatment of medical devices with reactive hydrophilic polymers
US20020120333A1 (en) * 2001-01-31 2002-08-29 Keogh James R. Method for coating medical device surfaces
WO2003063926A1 (en) * 2002-02-01 2003-08-07 Sustech Gmbh & Co. Kg Stellate prepolymers for the production of ultra-thin coatings that form hydrogels
WO2005102675A2 (en) * 2004-04-21 2005-11-03 Novartis Ag Curable colored inks for making colored silicone hydrogel lenses

Patent Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2000072052A1 (en) * 1999-05-20 2000-11-30 Bausch & Lomb Incorporated Surface treatment of medical devices with reactive hydrophilic polymers
US20020120333A1 (en) * 2001-01-31 2002-08-29 Keogh James R. Method for coating medical device surfaces
WO2003063926A1 (en) * 2002-02-01 2003-08-07 Sustech Gmbh & Co. Kg Stellate prepolymers for the production of ultra-thin coatings that form hydrogels
WO2005102675A2 (en) * 2004-04-21 2005-11-03 Novartis Ag Curable colored inks for making colored silicone hydrogel lenses

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
HEGGLI M. ET AL: "Michael-type addition as a tool for surface functionalization", BIOCONJUGATE CHEM., vol. 14, 2003, pages 967 - 973, XP002485565 *

Also Published As

Publication number Publication date
WO2008005752A2 (en) 2008-01-10
EP2035050A2 (en) 2009-03-18

Similar Documents

Publication Publication Date Title
WO2008005752A3 (en) Modification of surfaces of polymeric articles by michael addition reaction
WO2009091728A3 (en) Polymerizable contact lens formulations and contact lenses obtained therefrom
WO2009044912A1 (en) Hydrophilic coating agent, hydrophilic coating film, and hydrophilic base
WO2007052260A3 (en) Use of poss nanostructured molecules for hydrophobic and self cleaning coatings
ATE481118T1 (en) HYDROPHILIC COATING WITH A POLYELECTROLYTE
WO2008005643A3 (en) Carboxylic siloxanyl monomers with pendant polymerizable groups
WO2006013337A3 (en) Tissue-adhesive materials
WO2008023048A3 (en) Method of coating a contact lens
WO2007136504A3 (en) Medical devices having bioactive surfaces
EP4276161A3 (en) Low particulate lubricious coating with vinyl pyrrolidone and acidic polymer-containing layers
WO2009137046A3 (en) Novel crosslinked polymeric substrates methods of preparation and end use applications of the substrates
WO2008030383A3 (en) Medical devices having nanostructured coating for macromolecule delivery
BR112013001922A2 (en) scratch and abrasion resistant coating process and physical entanglement of plastic substrates, more particularly poly (methyl methacrylate), with nanocomposite coating material
WO2008034047A3 (en) Endoprosthesis with adjustable surface features
WO2008087980A1 (en) Polymerizable composition containing hydrophilic monomer and dental material
DE60202866D1 (en) COATINGS OF TYPE "BOTTLE-BRUSH" WITH SWIVELED POLYMERS
EP2052855A3 (en) Barrier film and device
WO2012082856A3 (en) Improved waterless printing members and related methods
TW200718723A (en) Moisture curable silylated polymer containing free polyols for coating, adhesive and sealant application
DE602007010979D1 (en) PROCESS FOR COATING CONTACT LENSES
EP2301596A3 (en) Medical device having a lubricious coating with a hydrophilic compound in an interlocking network
WO2012006135A3 (en) Fluorinated polymers and lubricious coatings
WO2009158068A3 (en) Methods of application of coatings composed of hydrophobic, high glass transition polymers with tunable drug release rates
WO2013001506A3 (en) Medical and non-medical devices made from hydrophilic rubber materials
EP2287215A3 (en) Production method of water-absorbent resin, water-absorbent resin and usage of water-absorbent resin

Legal Events

Date Code Title Description
WWE Wipo information: entry into national phase

Ref document number: 200780024792.4

Country of ref document: CN

121 Ep: the epo has been informed by wipo that ep was designated in this application

Ref document number: 07812327

Country of ref document: EP

Kind code of ref document: A2

DPE1 Request for preliminary examination filed after expiration of 19th month from priority date (pct application filed from 20040101)
WWE Wipo information: entry into national phase

Ref document number: 2009518510

Country of ref document: JP

WWE Wipo information: entry into national phase

Ref document number: 2007812327

Country of ref document: EP

NENP Non-entry into the national phase

Ref country code: DE

NENP Non-entry into the national phase

Ref country code: RU

NENP Non-entry into the national phase

Ref country code: JP

NENP Non-entry into the national phase

Ref country code: JP