[go: up one dir, main page]

WO2008004902A3 - Protéine, ses fragments et leur utilisation - Google Patents

Protéine, ses fragments et leur utilisation Download PDF

Info

Publication number
WO2008004902A3
WO2008004902A3 PCT/PL2007/000045 PL2007000045W WO2008004902A3 WO 2008004902 A3 WO2008004902 A3 WO 2008004902A3 PL 2007000045 W PL2007000045 W PL 2007000045W WO 2008004902 A3 WO2008004902 A3 WO 2008004902A3
Authority
WO
WIPO (PCT)
Prior art keywords
fragment
protein
pharmacy
medicine
extract
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Ceased
Application number
PCT/PL2007/000045
Other languages
English (en)
Other versions
WO2008004902A2 (fr
Inventor
Andrzej Gamian
Danuta Witkowska
Bernadeta Szostko
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Instytut Immunologii i Terapii Doswiadczalnej PAN
Instytut Przemyslu Farmaceutycznego
Original Assignee
Instytut Immunologii i Terapii Doswiadczalnej PAN
Instytut Przemyslu Farmaceutycznego
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Instytut Immunologii i Terapii Doswiadczalnej PAN, Instytut Przemyslu Farmaceutycznego filed Critical Instytut Immunologii i Terapii Doswiadczalnej PAN
Publication of WO2008004902A2 publication Critical patent/WO2008004902A2/fr
Publication of WO2008004902A3 publication Critical patent/WO2008004902A3/fr
Anticipated expiration legal-status Critical
Ceased legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/195—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria
    • C07K14/24—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria from Enterobacteriaceae (F), e.g. Citrobacter, Serratia, Proteus, Providencia, Morganella, Yersinia
    • C07K14/25—Shigella (G)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
    • Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
    • Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Medicinal Chemistry (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Peptides Or Proteins (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)

Abstract

La protéine isolée faisant l'objet de la présente invention, présente dans l'extrait de protéines de membrane externe bactérienne, ainsi que ses fragments, sont appropriés à une utilisation en médicine et en pharmacie, particulièrement pour la production de vaccins et de tests diagnostiques.
PCT/PL2007/000045 2006-07-04 2007-07-04 Protéine, ses fragments et leur utilisation Ceased WO2008004902A2 (fr)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
PL380105A PL380105A1 (pl) 2006-07-04 2006-07-04 Białko, jego fragment oraz ich zastosowania
PLP380105 2006-07-04

Publications (2)

Publication Number Publication Date
WO2008004902A2 WO2008004902A2 (fr) 2008-01-10
WO2008004902A3 true WO2008004902A3 (fr) 2008-07-10

Family

ID=38895028

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/PL2007/000045 Ceased WO2008004902A2 (fr) 2006-07-04 2007-07-04 Protéine, ses fragments et leur utilisation

Country Status (2)

Country Link
PL (1) PL380105A1 (fr)
WO (1) WO2008004902A2 (fr)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
PL220297B1 (pl) * 2012-11-07 2015-10-30 Wrocławskie Ct Badań Eit & Spółka Z Ograniczoną Odpowiedzialności& Epitop i jego zastosowanie

Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2002057780A1 (fr) * 2001-01-18 2002-07-25 Newcastle University Ventures Ltd. Biocapteur a proteines transmembranaires attachees de maniere covalente
WO2004091372A2 (fr) * 2003-04-11 2004-10-28 Cedars-Sinai Medical Center Procedes pour faire une estimation du phenotype d'un patient souffrant de la maladie de crohn par la reaction serologique i2, ompc et asca

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2002057780A1 (fr) * 2001-01-18 2002-07-25 Newcastle University Ventures Ltd. Biocapteur a proteines transmembranaires attachees de maniere covalente
WO2004091372A2 (fr) * 2003-04-11 2004-10-28 Cedars-Sinai Medical Center Procedes pour faire une estimation du phenotype d'un patient souffrant de la maladie de crohn par la reaction serologique i2, ompc et asca

Non-Patent Citations (15)

* Cited by examiner, † Cited by third party
Title
ALBERTI SEBASTIAN ET AL: "A porin from Klebsiella pneumoniae: Sequence homology, three-dimensional model, and complement binding", INFECTION AND IMMUNITY, vol. 63, no. 3, 1995, pages 903 - 910, ISSN: 0019-9567 *
DATABASE Geneseq [online] 13 January 2005 (2005-01-13), "Outer membrane protein c, OmpC, precursor, SEQ ID 10.", XP002478621, retrieved from EBI accession no. GSP:ADT50378 Database accession no. ADT50378 *
DATABASE Geneseq [online] 15 October 2002 (2002-10-15), "E coli outer membrane protein OmpF.", XP002478623, retrieved from EBI accession no. GSP:AAO18573 Database accession no. AAO18573 *
DATABASE Geneseq [online] 20 December 1999 (1999-12-20), "E. coli wild-type ompC protein.", XP002478622, retrieved from EBI accession no. GSP:AAY42549 Database accession no. AAY42549 *
DATABASE UniProt [online] 1 June 2003 (2003-06-01), "Outer membrane protein 1a (Ia;b;F).", XP002478625, retrieved from EBI accession no. UNIPROT:Q83RY4 Database accession no. Q83RY4 *
DATABASE UniProt [online] 1 March 2003 (2003-03-01), "Outer membrane protein C precursor (Porin ompC) (Outer membrane protein 1B).", XP002478619, retrieved from EBI accession no. UNIPROT:Q8CVW1 Database accession no. Q8CVW1 *
DATABASE UniProt [online] 1 November 1996 (1996-11-01), "Outer membrane protein C precursor (Porin ompC) (Porin ompk36).", XP002478627, retrieved from EBI accession no. UNIPROT:Q48473 Database accession no. Q48473 *
DATABASE UniProt [online] 15 December 1998 (1998-12-15), "Outer membrane protein F precursor (Porin ompF) (Outer membrane protein S3).", XP002478624, retrieved from EBI accession no. UNIPROT:Q56113 Database accession no. Q56113 *
DATABASE UniProt [online] 15 March 2005 (2005-03-15), "Outer membrane protein C precursor (Porin ompC).", XP002478626, retrieved from EBI accession no. UNIPROT:P0A263 Database accession no. P0A263 *
DATABASE UniProt [online] 6 December 2005 (2005-12-06), "Outer membrane protein 1b.", XP002478620, retrieved from EBI accession no. UNIPROT:Q32I16 Database accession no. Q32I16 *
JIN QI ET AL: "Genome sequence of Shigella flexneri 2a: Insights into pathogenicity through comparison with genomes of Escherichia coli K12 and O157.", NUCLEIC ACIDS RESEARCH, vol. 30, no. 20, 15 October 2002 (2002-10-15), pages 4432 - 4441, XP002478617, ISSN: 0305-1048 *
MOLLOY MARK P ET AL: "Extraction of membrane proteins by differential solubilization for separation using two-dimensional gel electrophoresis", ELECTROPHORESIS, vol. 19, no. 5, May 1998 (1998-05-01), pages 837 - 844, XP002478715, ISSN: 0173-0835 *
NEGM R S ET AL: "The porin OmpC of Salmonella typhimurium mediates adherence to macrophages.", CANADIAN JOURNAL OF MICROBIOLOGY AUG 1999, vol. 45, no. 8, August 1999 (1999-08-01), pages 658 - 669, XP002478618, ISSN: 0008-4166 *
WITKOWSKA DANUTA ET AL: "Enterobacterial 38-kDa outer membrane protein is an age-dependent molecular marker of innate immunity and immunoglobulin deficiency as results from its reactivity with IgG and IgA antibody", FEMS IMMUNOLOGY AND MEDICAL MICROBIOLOGY, vol. 48, no. 2, November 2006 (2006-11-01), pages 205 - 214, XP002478615, ISSN: 0928-8244 *
YANG FAN ET AL: "Genome dynamics and diversity of Shigella species, the etiologic agents of bacillary dysentery.", NUCLEIC ACIDS RESEARCH 2005, vol. 33, no. 19, 2005, pages 6445 - 6458, XP002478616, ISSN: 1362-4962 *

Also Published As

Publication number Publication date
PL380105A1 (pl) 2008-01-07
WO2008004902A2 (fr) 2008-01-10

Similar Documents

Publication Publication Date Title
WO2011157741A3 (fr) Conjugués anticorps humain-médicament contre le facteur tissulaire
EP2450360A3 (fr) (S)-N-Méthylnaltrexone
WO2008021076A3 (fr) Vaccins à base de matrice protéique et procédés de fabrication et d'administration de tels vaccins
WO2011143624A3 (fr) Anticorps monoclonaux anti-cd47 humanisés et chimères
WO2007007173A3 (fr) Nouveaux anticorps anti-madcam
MX2007007033A (es) Estreptococus del grupo b.
EA019476B9 (ru) АНТИТЕЛА ПРОТИВ IL-23p19 И ИХ ПРИМЕНЕНИЕ
EP2433959A3 (fr) Identification des antigènes associés aux tumeurs pour diagnostics et thérapie
WO2004013180A3 (fr) Anticorps anti-alpha-fetoproteine immu31, proteines de fusion et procedes d'utilisation de ceux-ci
WO2007116360A3 (fr) Anticorps se liant à la protéine tyrosine phosphatase bêta humaine (hptpbêta) et utilisations correspondantes
EP2457928A3 (fr) Anticorps monoclonal humain spécifique d'une tumeur
IL214779A (en) Isolated monoclonal antibody or epitope-binding antibody on cadm1, methods of preparation and use for drug preparation
WO2004111081A3 (fr) Peptides antigeniques de coronavirus de sars, et utilisations
WO2019241672A3 (fr) Variants de piline comp glycosylés, leurs procédés de fabrication et leurs utilisations
EP2251035A3 (fr) Nouveaux facteurs de virulence de la pneumonie à streptocoques
WO2008054595A3 (fr) Étiquettes moléculaires contrôlées par médicament
WO2009115509A3 (fr) Fragments de protéine antigénique de streptococcus pneumoniae
WO2009020553A3 (fr) Antigènes chlamydiens
WO2007075915A3 (fr) Anticorps monoclonaux utilises contre des orthopoxvirus
WO2008004902A3 (fr) Protéine, ses fragments et leur utilisation
WO2007118077A3 (fr) Catalase-peroxydase mycobactérienne utilisée dans le cadre du diagnostic et du traitement d'une sarcoïdose
BRPI0818715A2 (pt) proteína m de streptococcus, fragmentos imunogênicos, ácidos nucléicos e métodos de uso
DE602006012463D1 (de) Konjugat mit p21-protein zur krebsbehandlung
PL401502A1 (pl) Epitop i jego zastosowanie
WO2007054537A8 (fr) Nouvelle bactérie et vaccin

Legal Events

Date Code Title Description
121 Ep: the epo has been informed by wipo that ep was designated in this application

Ref document number: 07747754

Country of ref document: EP

Kind code of ref document: A2

NENP Non-entry into the national phase

Ref country code: DE

NENP Non-entry into the national phase

Ref country code: RU

122 Ep: pct application non-entry in european phase

Ref document number: 07747754

Country of ref document: EP

Kind code of ref document: A2