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WO2008002175A1 - Régime hebdomadaire destiné aux patients oncologiques et aux personnes ayant une durée de vie remarquablement longue - Google Patents

Régime hebdomadaire destiné aux patients oncologiques et aux personnes ayant une durée de vie remarquablement longue Download PDF

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Publication number
WO2008002175A1
WO2008002175A1 PCT/RU2006/000340 RU2006000340W WO2008002175A1 WO 2008002175 A1 WO2008002175 A1 WO 2008002175A1 RU 2006000340 W RU2006000340 W RU 2006000340W WO 2008002175 A1 WO2008002175 A1 WO 2008002175A1
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cancer
patient
green
flour
fresh
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Russian (ru)
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Vulf Abramovich Laskin
Alexandr Vladimirovich Baljura
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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/28—Asteraceae or Compositae (Aster or Sunflower family), e.g. chamomile, feverfew, yarrow or echinacea
    • A61K36/282—Artemisia, e.g. wormwood or sagebrush
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23L—FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES, NOT OTHERWISE PROVIDED FOR; PREPARATION OR TREATMENT THEREOF
    • A23L33/00—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof
    • A23L33/10—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof using additives
    • A23L33/105—Plant extracts, their artificial duplicates or their derivatives
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23L—FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES, NOT OTHERWISE PROVIDED FOR; PREPARATION OR TREATMENT THEREOF
    • A23L33/00—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof
    • A23L33/10—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof using additives
    • A23L33/115—Fatty acids or derivatives thereof; Fats or oils
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23L—FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES, NOT OTHERWISE PROVIDED FOR; PREPARATION OR TREATMENT THEREOF
    • A23L33/00—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof
    • A23L33/40—Complete food formulations for specific consumer groups or specific purposes, e.g. infant formula
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/12—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/56—Materials from animals other than mammals
    • A61K35/60—Fish, e.g. seahorses; Fish eggs
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/06—Fungi, e.g. yeasts
    • A61K36/07—Basidiomycota, e.g. Cryptococcus
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/23—Apiaceae or Umbelliferae (Carrot family), e.g. dill, chervil, coriander or cumin
    • A—HUMAN NECESSITIES
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    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/31—Brassicaceae or Cruciferae (Mustard family), e.g. broccoli, cabbage or kohlrabi
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/48—Fabaceae or Leguminosae (Pea or Legume family); Caesalpiniaceae; Mimosaceae; Papilionaceae
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/63—Oleaceae (Olive family), e.g. jasmine, lilac or ash tree
    • A—HUMAN NECESSITIES
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    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
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    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/67—Piperaceae (Pepper family), e.g. Jamaican pepper or kava
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    • A61K36/18—Magnoliophyta (angiosperms)
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    • A—HUMAN NECESSITIES
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    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/73—Rosaceae (Rose family), e.g. strawberry, chokeberry, blackberry, pear or firethorn
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/73—Rosaceae (Rose family), e.g. strawberry, chokeberry, blackberry, pear or firethorn
    • A61K36/738—Rosa (rose)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/75—Rutaceae (Rue family)
    • A61K36/752—Citrus, e.g. lime, orange or lemon
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/81—Solanaceae (Potato family), e.g. tobacco, nightshade, tomato, belladonna, capsicum or jimsonweed
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/82—Theaceae (Tea family), e.g. camellia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/87—Vitaceae or Ampelidaceae (Vine or Grape family), e.g. wine grapes, muscadine or peppervine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/88—Liliopsida (monocotyledons)
    • A61K36/896—Liliaceae (Lily family), e.g. daylily, plantain lily, Hyacinth or narcissus
    • A61K36/8962—Allium, e.g. garden onion, leek, garlic or chives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents

Definitions

  • the invention relates to medicine, and specifically to oncology and gerontology, and relates to a diet proposed for the treatment of cancer patients, in addition, it can be successfully used for centenarians.
  • the incidence of cancer has a positive trend: about 5 million people die of cancer every year in the world, and 9 million patients who first have malignant neoplasms face a difficult survival task (Kruglyak L.G. Rational nutrition in cancer, St. Moscow: IG "BEC", 2004, p.6).
  • breast cancer breast cancer
  • operative radiation operative radiation
  • chemotherapy systemic effects
  • Radiotherapy and chemotherapy are nonspecific and damage not only tumor cells, but also normal, actively proliferating cells, including immunocompetent ones. Cytostatics contribute to the radical “knocking out” of a lymphocyte clone (LF) activated to a specific antigen, disrupting an initially defective immune defense. In some cases (IP) it is so suppressed that the ability to independently restore the immune response (AI) does not appear even after a break in treatment.
  • LF lymphocyte clone
  • IP immune response
  • AI immune response
  • the total number of LF in the blood decreases by 50% of the initial number, CD4 cells by 60%, the immunoregulatory index (IRI) drops to 1.5 and remains at this level for 2-3 years.
  • Radiation therapy also has an immunosuppressive effect.
  • the suppression of humoral and cellular immune responses is accompanied by an increased risk of dissemination of an existing tumor, the emergence of new malignant neoplasms, and superinfection.
  • the myelodepressive effect of cytostatics complicates the specific treatment, makes it necessary to reduce single and total doses of drugs, prescribe expensive colony-stimulating factors.
  • Antitumor agents of various classes and mechanism of action, radiation therapy induce staged in the patient's body changes in antioxidant activity (AOA) of lipids and have one common feature: at one stage or another they reduce the level of antioxidant reactions.
  • AOA antioxidant activity
  • BIOCKAH C biologically active additives
  • This dietary supplement is a natural product extracted from Siberian larch wood.
  • the main component of dietary supplement is bioflavonoid-dihydroquercytin.
  • the total content of active substances in the dietary supplement is at least 90%.
  • the specified flavonoid is one of the strongest natural antioxidants, which causes a wide range of biochemical activity of “BIOCKAH C”.
  • a known method of corrective therapy for the complex treatment of breast cancer including the appointment of biologically active additives "BIOCKAH C" two days before the start of chemotherapy at a dose of 10-15 ml twice a day, and before the start and during chemotherapy, the indicators of the number of leukocytes in blood and transaminase levels and with a decrease in the number of leukocytes to 3, 3xlO 3 / L - 3.0xl0Vl and / or an increase in the level of transaminases by 1.5-2 times compared with the norm, the dose of “BIOCKAH C” is doubled, while the biologically active additive “ BIOCKAH C "breed 0.9% f isological solution (patent RU N ° 2223779, IPC 7 A 61 K 35/78, A 61 B 5/145, A 61 P 35/00, 2002).
  • knotweed birdlance
  • dioica nettle grass field horsetail grass
  • marshmallow roots barberry grass
  • Chernobyl grass five-lobed motherwort grass
  • valerian grass roots grasshopper grass
  • wild roots porcini mushroom
  • mummy bear bile
  • forgotten roots common caraway seeds
  • linden flowers lingonberry leaves
  • medicinal verbena grass grass of the uterine uterus (one-sided ortilia)
  • common rhizome grass anise seeds go, pink periwinkle grass, goose cinquefoil (whole plant)
  • angelica roots common flax grass
  • saber-eared marsh roots high root roots
  • birch buds ordinary hop cones
  • medicinal drop letters orthosiphon grass (Japanese tea bud)
  • infusion in accordance with the collection of medicinal plants taken for decoction, they take in the given proportions the inflorescences of tansy ordinary, sweet clover, common wormwood, motherwort five-lobed, flowers of marigold medicinal, mint field, celandine big, oregano, marsh rosemary, mother-and- stepmother, drooping birch, dioica nettle or marigold flowers, motherwort five-lobed, medicinal melissa, hawthorn blood-red, yarrow, chamomile, large celandine, common wormwood , white mistletoe, large plantain, immortelle sandy (patent RU Xa 21 b 1979, IPC 7 A 61 K 35/78, 1999)
  • the proposed phytocomplex provides an increase in the protective ability of the body and is used to treat various diseases, including breast cancer.
  • various diseases including breast cancer.
  • herbal preparations are their versatility and gentle effects on the body, the absence or insignificant side effect, and good tolerance to patients.
  • a known composition having antitumor, hepatoprotective and immunostimulating effects including dry extract of hill hodgepodge grass, dry extract of chaga mushroom and dry extract of Kuril tea in the following ratio of components, wt.%: Dry extract of fungus mushroom 40-80, dry extract of Kuril tea 12, 5-37.5, dry extract of grass hodgepodge hill 7.5-22.5 (patent RU JVb 2221586, IPC 7 A 61 K 35/78, 2002)
  • neoplasms which is an alcohol tincture of herbs with antitumor activity, and herbs that have a general strengthening effect on the body and stimulate the body's immune system and tone.
  • the composition of the product includes: calamus marsh, marigold, rosehip, knotweed, immortelle, viburnum, marin root, St. John's wort, horsetail, pink periwinkle, blueberries, black currants, horse sorrel, black mulberries, celandine, hawthorn, medicinal comfrey, licorice, Chaga , cinquefoil erect and garlic (patent RU N ° 2044547, IPC 6 A 61 K 35/78, 1995).
  • a means for the prevention and postoperative treatment of malignant neoplasms consisting of two tinctures and a decoction, which include: tincture 1 (alcohol) - angelica root, calamus root, ephedra grass and plantain grass; in tincture 2 (alcohol) - the root of the step, the root of the decopus and the grass of ephedra; in broth (distilled water) - chaga, wild rosemary, St.
  • Another analogue can be noted - a phytopreparation, which is prepared from medicinal mushrooms and plants containing karyoclastic poisons (patent RU Ns 2074731, IPC 6 A 61 K 35/78, 1997).
  • compositions described above The disadvantage of all these compositions is the high toxicity of herbal medicines based on karyoclast poisons, which act not only on atypical cells, but also on the whole organism.
  • the main task when using the compositions described above is to reduce the harmful effects of karyoclastic plant poisons on healthy tissues of the body, while maintaining and strengthening them effects on malignant neoplasms, as well as strengthen the effect of x-ray therapy and chemotherapy with a decrease in their dosage, which does not reduce the effectiveness of the therapy, to prevent the development of leuko- and thrombocytopenia, metastasis and relapse in the postoperative period.
  • a dose of deoxyribonucleic acid and antitumor phytopreparations are administered, as well as additionally antitoxic and / or antianemic and / or tonic and / or antihistamine and / or immunomodulating and / or diuretic drugs herbal remedies.
  • the main phytopreparation is prepared from phyto-collection, which includes medicinal plants and mushrooms in the following ratio of components by weight: corm seeds of Colchicum autumn 2-60, Colchicum vulgaris 2-60, Pedophilus thyroid (resin rhizomes) 20-40, gorinik Russian 200 - 400, pink periwinkle 100–200, spotted hemlock 1–20, Dzhungarian aconite 1–20, large celandine 2–60, dipelia 20–60, small-leaf burser 100–200 fly agaric, 200–600 red fly agaric, 100–200 long-legged talker, honey agaric winter 100 - 200, thick pig 100 - 200, giant raincoat th 60-100.
  • phyto-collection which includes medicinal plants and mushrooms in the following ratio of components by weight: corm seeds of Colchicum autumn 2-60, Colchicum vulgaris 2-60, Pedophilus thyroid (resin rhizomes) 20-40, gorinik Russian 200 - 400, pink periwinkle 100
  • An antitumor herbal preparation is prepared from a phyto-collection, which includes medicinal plants in the following ratio of components, parts by weight: plantain 4-6, cornstalk 2-6, cornflower stalk 1-2, narrow-leaved 1-2, field horsetail 2-6, Chaga 6 - 10, purifications purple 2 - 4.
  • An antitoxic phytopreparation is prepared from phyto-collection, which includes medicinal plants in the following ratio of components, parts by weight: milky-flowered peony 1 - 8, Chinese remany 1 - 8, poria coconut 1 - 8, atractylodes ovoid 1 - 2, Ural licorice 1 - 2 .
  • An antianemic herbal preparation is prepared from a phyto-collection, which includes medicinal plants in the following ratio of components, parts by weight: nippon dioscorea 10–20, yellow red 1–3, cornflower stalk 1–5, Pacific frangipani 10–40, fragrant nippon 1–1 3, Scutellaria baicalensis 20–40, Chinese romania 10–30, St. John's wort perforated 10–30.
  • a tonic phytopreparation is prepared from phyto-collection, which includes medicinal plants in the following ratio of components, parts by weight: real ginseng 10–50, asterisk 10–50, bird highlander 10–50, prickly eleutherococcus 5–10, pink rhodiola 5–10 , Himalayan rhododendron 1–3, Chinese magnolia vine 1–3, heart-shaped aralia 1–3, aloe 5–30, pakhima cholean 5–30.
  • An antihistamine phytopreparation is prepared from phyto-collection, which includes medicinal plants in the following ratio of components, parts by weight: Ural licorice 5 - 10, evasive peony 10 - 30, Indian colosant 1 - 3, Baikal skullcap 10 - 30.
  • a diuretic phytopreparation is prepared from a phyto-collection, which includes medicinal plants in the following ratio of components, parts by weight: tansy 1–5, Ural licorice 10–30, paper therapanax 1–5, field horsetail 10–30, St. John's wort perforated 10–30, hairy wormwood 1–3, Chernobyl 10–30, buds foliate 5–10, plantain large 10–40, nettle 1–10, mountaineer 10–30 (patent RU JN ° 2161040, IPC 7 A 61 K 35/78, A 61 P 35/00, 2000).
  • Extracts of karyoclastic poisons acting on tumors as mitotic poison, inhibit cell division in metaphase with sharp damage to cell nuclei and gluing of chromosomes, i.e. these poisons have a cytotoxic, anti-miotic, and in some cases inhibitory effect against atypical cancer cells.
  • Cells of malignant tumors which have a characteristic spindle-shaped shape, become rounded, and their cytoplasm and nucleus undergo changes (fragmentation, pycnosis), leading to atypical cells to death.
  • the simultaneous administration of a complex of karyoclastic poisons into the patient's body increases the radiosensitivity of tissues and the effectiveness of x-ray therapy, enhancing cytostatic and cytotoxic the effect of radiation due to the positive effect on the metabolism of amino acids (glycine, tyrosine, leucine, tryptophan, thionine) in inoperable cancer patients.
  • amino acids glycine, tyrosine, leucine, tryptophan, thionine
  • karyoclastic poisons and medicinal plants is determined by the sum of biologically active substances contained in various parts of plants and fungi, the most important of which is colchicine and its derivatives - colchicerin, narcotine, and the amount of alkaloids.
  • Colchicine is effective in malignant neoplasms, a characteristic feature of which is intensive cell division. It affects the functional activity of cells, in particular, the release of prolactin and growth hormone by the functioning pituitary carcinoma cells, 2-3 times increases the intracellular concentration of prolactin and growth hormone, blocks the inhibitory effect of hydrocortisone on the accumulation of prolactin and growth hormones inside the cells. Colchicine and its derivatives are effective against lymphosarcoma and adenocarcinoma.
  • colchicine synergists alkaloids with a stilbamine group - berberine, bulbocapnin, d-tubocurarine, vetrin, strychnine, papaverine, thebaine, corridine, laurotetaine, glaucine, aporfin, morphoteba.
  • the mechanism of action of the drug containing these substances is as follows: there are two receptors for mitotic poisons in the cell; the binding of one of these receptors causes a cell division disorder, whereas when the second receptor binds, the process of cell division proceeds normally.
  • the alkaloids bind the second receptor, as a result of which a large amount of colchicine binds to the first receptor, and the effect on mitosis is enhanced.
  • Muscle poisons of the strychnine type enhance the antimitotic effect by analogy with the chemistry of the cell spindle and muscles in the contracture phase. But since the spindle is still not completely identical to myofibrils, muscle poisons do not immediately act on it, their effect appears only after the spindle damaged by colchicine becomes even more similar to muscle fiber.
  • colchamine Another biologically active substance contained in the plants of the medicinal phytosport used in the implementation of the claimed invention is colchamine (omain), which is 7-8 times less toxic than colchicine.
  • Colchamine affects the metabolism of aminoxylot, normalizing it. When using colchamine, inhibition of glycine metabolism in the spleen and kidneys is more pronounced, tyrosine in the tissues of the brain and liver, leucine in the kidneys, tryptophan in the liver and spleen, methionine in the tissues of the liver, spleen and kidneys. Colchamine stimulates erythropoiesis somewhat.
  • Plants used in treatment affect thiodisulfide metabolism, redox enzymes, and regulatory proteins of signal-transmitting receptor systems that control the metabolic processes and activity of the genetic apparatus of cells, mainly organs of immune and hematopoiesis.
  • immunomodulators Under the influence of plant collections, immunomodulators have a differentiated effect on normal and pathologically altered cells (atypical and virus-modified), as a result of which the proliferation and differentiation of normal cells is stimulated along with the induction of apoptosis mechanisms in transformed cells.
  • the compositions mentioned above are used as monotherapy in inoperable cases of the 3-4 stage of the disease and as an accompaniment to chemotherapy, radiological and surgical treatment.
  • cyclophosphamide DNA damage.
  • the main side effects of cyclophosphamide are hematopoiesis, immunosuppression, and a hepatotoxic effect is also noted.
  • the main objective of this direction of the fight against malignant neoplasms is to expand the arsenal of products from plant materials, which simultaneously increase the antitumor activity of chemotherapy drugs and reduce their toxicity, in particular, hepatotoxicity.
  • lohein as a means of increasing the antitumor and antimetastatic activity of cyclophosphamide (patent RU JCH 2225720, IPC 7 A 61 K 35/78, A 61 P 35/00, 35/04, 2002)
  • vitamin A retinoids, sodium butyrate, vitamin D, perilyl alcohol, limonene, farnesyltransferase inhibitors
  • non-steroidal anti-inflammatory drugs indomethacin, voltaren, aspirin, cyclooxygenase-2 inhibitors and lipoxygenase
  • carcinogen absorption, activation and detoxification modulators calcium, phenethylisothiocyanate, indol-3-carbinol, ursodiol, oltipraz, N-acetylcysteine
  • epselon amino caproic acid antioxidants (beta-carotene and other carotenoids, selenium, vitamin E, P-methoxyphenol and other flavonoids, butylhydroxyanisole); antiproliferative agents (alpha-carotene and other carotenoids, selenium, vitamin E, P-methoxyphenol and other flavonoids, butylhydroxyanisole); antiproliferative agents (
  • wheat bran consists of half of dietary fiber - natural polymers: cellulose, hemicellulose, pectin, lignin, and also contain a complex of essential macro- and microelements, B vitamins. It was found that in experimental, epidemiological and clinical studies they prevent the occurrence of and the development of colon and breast cancer (Fergusop LR, Narris PJ. Protestiop agaipst sapper bu wh Vintaget bran ⁇ role thereafter hereby dieter fibr apd rhutochemisls. ⁇ ur. J. Sapser ⁇ rev. 1999, 00340
  • wheat bran causes increased gas formation in the intestine, with prolonged use it is excreted from the body, thus causing a deficiency of calcium, magnesium, iron, zinc and other essential micronutrients, which. may lead to diarrhea. They are also contraindicated in peptic ulcer disease, in addition, the chemical composition of wheat bran is multicomponent and unstable, which complicates their standardization.
  • BST peat-based biostimulants
  • BST is obtained from sphagnum peat as follows. The initial peat is subjected to alkaline hydrolysis, the resulting peat slurry is then oxidized with atmospheric oxygen at elevated temperature and pressure, the products are neutralized with acid and precipitated, after which they receive BST from the modification.
  • BST or other peat oxyhumate belongs to the class of high molecular weight organic polymers, is a product of black or dark brown color, odorless and tasteless, non-volatile, readily soluble in alkalis and alcohols, insoluble in acids and water (Mayakova E.F. and etc., Technological process for the production of growth biostimulant at Boksitogorsk biochemical plant. Proceedings of VNIITP, 1987, issue 59, p.83-88).
  • BST as an additive to the diets of cattle, pigs, and broiler chickens is known to increase the general nonspecific resistance, improve metabolism, growth-promoting action and increase productivity.
  • BST as a stimulator of hair growth is known (patent RU Ns 2045948).
  • Bespalov V.G. et al. first proposed the use of BLS as an anti-cancer agent for cancer prevention.
  • Known dietary supplement for food including an immunobiological preparation, which contains human recombinant alpha-2-interferon and immunoglobulins at the rate of 10 3 -10 ME per 1 g of an acceptable food product.
  • This dietary supplement significantly increases the body's defenses, however, it contains components obtained by expensive and complex methods of genetic engineering, while the biological spectrum of such an additive is quite narrow, because it introduces only certain components of the immune system into the body.
  • a dietary supplement was proposed based on a biologically active substance isolated from mushrooms, containing a composition of biologically active substances in vegetable oil, characterized by the following content of components, in
  • lipids 2000 - 4000 mg 100 ml of an oil solution: lipids 2000 - 4000 mg, phospholipids 800 - 1200 mg, ubiquinone QlO 0.4 - 1.2 mg, vegetable oil up to 100 ml.
  • This biologically active additive may contain, in addition to the mentioned components, lactose, with the following content of components in the capsule, 1 gram: lipids 30-70 mg, phospholipids 14-20 mg, ubiquinone QlO 0.014-0.02 mg, lactose up to 1 gram.
  • said biologically active additive may contain a composition of biologically active substances in an aqueous alcohol solution in the following ratio of components in 100 ml of an aqueous alcohol solution: lipids 100-200 mg, phospholipids 40-60 mg, ubiquinone QlO 0, 02-0.06 mg, enzymes with protease, including collagenase, chitinase and lipase activities 20-30 mg, phospholipase AII 20-50 mg, ribonuclease 15-25 mg, ⁇ -glucan 200-400 mg, ethanol 7000-10000 mg, water up to 100 ml (patent RU JNa 2177699, IPC 7 A 23 L 1/29, 1/30, 1/054, 2000).
  • diet means a way of life, but later on “diet” began to denote a certain method of nutrition, a therapeutic factor (Shevchenko VP Long-liver diet. Special menu for every day for various diseases, for weight loss. M. , Centropolygraph, 2003, p. 318).
  • fats found in meat, pastries and snacks fats found in meat, pastries and snacks. These fats provide 34% of the calories an average American consumes. Reducing this amount to 30% of all calories consumed can reduce the risk of cancer. Considering that 1 gram of fat contains 9 calories, 30% will correspond to: 57 grams for a diet of 1700 calories, 67 g - 2000 cal., 73 g - 2200 cal., 83 g - 2500 cal.
  • C, A and E beta carotene
  • anti-cancer antioxidant suppressing carcinogenesis.
  • Vitamip A apd E Furth réeller Clues for Growth Sapser Reveptiop, Jörpal Otphe Natiopal Sapser Ipstitue, 1998, 90 (6), p. 414-415; Tomato S. et Al. 1991, 15 (6), P. 491-494).
  • Products containing vitamin E vegetable oils, green leaves of vegetables, eggs, seeds (grains) of wild rose.
  • the general anti-cancer effect is antioxidant, prevents fatty degeneration of the cell, stimulates the immune system; specifically prevents cancer of the skin, prostate and large intestine (Ogiipi I., Nasu K., Yamato mototo S., Nomuga T. On the appetitive optivitis fungus tepa lef. Agris Biol. Chet, 1988, 52, p. 1879-1880; Pastorino U. et al. Adjuvapt Treftef Stag 1 Lups Sapper with High-Vitamin A, Jufal Sopliso 1993, I, p. .
  • Products containing vitamin C red pepper, zucchini, broccoli, onions, garlic, tomatoes, turnips, citrus fruits, currants, strawberries, raspberries, mountain ash, rose hips.
  • the general anticancer effect - antioxidant inhibits the genetic rearrangement of the cell.
  • Specific effect - prevents cancer of the lung, trachea, esophagus, stomach, pancreas (Blosk G. et al. Vitamin C: A New Look. Ashials Optimal Medicine, 1991, 114 (10), p.909-910).
  • Products containing vitamin D liver, fish roe, salmon meat, liver of mammals and birds, eggs (yolk).
  • EGCG epilocatechins galates
  • General anti-cancer effect antioxidant, stimulates cellular immunity, suppresses fatty degeneration of cells, normalizes the water balance in the body.
  • Specific anti-cancer effect - protect the skin, mammary glands, large intestine, larynx from carcinogenic effects; protect the immune system from damage during chemotherapeutic treatment (Clark L.C. et al. Effects of Selenium Supplementation of Pharmaceuticals with Pharmaceuticals of Skiing, Medicine Pharmaceuticals, 24, 1996, 27 Medicinal -1963; Sembambia G., et al.
  • Products containing flavonoids are a large group of plant products containing phenolic components, which makes them similar to the hormones of the estrogen series of animals and humans: broccoli, seaweed, buckwheat, rosehips.
  • General anti-cancer effect suppress the mutation of the p53 suppressor.
  • Specific effect - inhibit the development of breast, prostate, and ovarian cancers .There Sapser Reveptiop Diet, St. Martin's Griffip, New York, 1994; Redappa P. et al.
  • Shiitake mushrooms and maitaki mushrooms have an immunostimulating effect (Kioka N. et al. Quercetip, and Bioflavoid, Iphibits the Iprease ⁇ f ⁇ umap Multidrig Residepse Gene (MDRl) Expreessi réellecep Servicess Sprint 30 Materialss Canalp Technologiess Canal 30 ⁇ e intendp réelles Canal 30 ⁇ e intendp réelleser 3. ; LaRossa L.M. et al.
  • GERMANY in garlic, mushrooms, shitaki, onions, etc .
  • IODINE in marine products, in all types of marine fish, garlic, legumes, mushrooms, etc .
  • SELENIUM - broccoli brown rice, chickens (not from an incubator), garlic, garlic feathers, brown seaweed, onions, salmon fish, tuna, sprouted wheat, alfalfa, big burdock root, capsicum, dill seeds, blueberry, parsley , raspberry leaves, yarrow, orange juice, barley, wholemeal bread; 6 000340
  • the animal organism has a previously unknown organ - the main stem cell (an analogue of the apical cell in plants), which coordinates growth and differentiation processes, is capable of counting past and upcoming cell divisions, the genetic program of which encodes an individual development program (cell division program, cytochronous potential). This program is laid during fertilization and the exhaustion of this program leads to the death of the body.
  • the duration of one cell division is considered to be an elementary unit of biological time - or a cytochron.
  • the sum of all cytochrons from the first division - zygotes to the last cell division - is the cytochronous potential of the organism's viability. It is very important that the genetic program of individual development determines, apparently, not only the number of past and upcoming cell divisions, but also the rate of differentiation of cells of various organs and tissues, and therefore their functional state.
  • accelerated metabolism and the associated reduction in the duration of cell divisions shorten the life of animals.
  • small animals with an accelerated metabolism pass their life path faster than large ones. The reason is that a small animal has a relatively large surface area per unit mass of body. Therefore, these animals lose heat much faster than large ones.
  • the main stem cell performs a certain number of “equal” and “constant” divisions. With equal divisions, daughter cells receive the same residual portion of the original cell division program that the mother stem cell had at the time of this division; if unequal - shortened division programs.
  • Daughter cells from equal divisions of the main stem cell become 1st order stem cells.
  • stem cells of organs, tissues, segments, etc. arise (stem cells of 1, 2,3 ... order).
  • a characteristic feature of stem cells is their ability to repeatedly replicate and differentiate into different types of secondary cells.
  • the functioning of the main stem cell in animals is probably mandatory during growth and maturation.
  • the death of the main stem cell its functions are taken over by the 1st order stem cells, in the case of the death of the 1st order stem cell, the 2nd order stem cells, etc. After exhausting the cytochronous potentials of stem cells, old age comes and death occurs.
  • the cells with the help of which information is transferred from the main stem cell to stem cells of the 1,2,3 ... order and further to the effector cells of various organs and tissues are, apparently, T-lymphocytes.
  • the data of A.G. Babayeva are interesting (Babaeva A.G. Regeneration and immunogenesis system. M., Medicine, 1985, p. 255.), From which it follows that the first partial hepatectomy increases the ability of lymphocytes to transmit repair information during reoperation. This fact resembles the phenomenon of immunological memory. In these cases, repeated regeneration proceeds much faster than the primary one (Babaeva A.G. Regeneration and immunogenesis system. M., Medicine, 1985, p. 255; Babaeva A.G., Zotikov E.A. Immunology of the processes of adaptive growth of proliferation and their disorders. M., Nauka, 1987, p.207).
  • the task underlying the present invention is to use a specific set of products for the treatment of cancer.
  • the technical result achieved in the process of using the claimed invention consists in the treatment of almost all varieties of malignant neoplasms without exception, without the use of radiation, chemotherapy, and in the process of nutrition with a specially selected set of products.
  • the well-known set of products including flour, whole grains, vegetable oil, boiled vegetables, additionally contains: dogrose flour, buckwheat, bran, green tea, bread from wholemeal flour, beans, lentils, fresh and dried shitaki or mantaka mushrooms, fresh salmon, non-incubator chickens, onions, garlic, carrots, tomatoes, white cabbage, Brussels sprouts, cauliflower, broccoli, red beets, pepper not bitter (red, yellow, green), celery, dill, parsley, wormwood, blueberries, grapes, pineapple, dad, lemon, orange, olive oil in the following ratio of components in g: rosehip flour 205 - 210, buckwheat groats 340 - 350, bran 65 - 70, green tea 32 - 35, wholemeal bread 980 - 1000, beans 190 - 200, lentils 190 - 200, shiitake or mantaka mushrooms fresh 290 - 300
  • the proposed list of products provides the patient with the necessary amount of vitamins C, A, D, E, K and biologically active flavonoids - quartzetine, luteolin, apiginin, bromelain, which have an anticarcinogenic effect and prevent the development of cancer at all 7 stages of its growth (Jonh Boik, Natural Comprods IP Sapser therapy, 2001).
  • the restoration of immunity is carried out through products containing selenium and vitamin E.
  • May hips contains: carotene (vitamin A precursor) 9, 75 mg%, pectin substances 14.1%, citric acid 1.58%, total sugars 23.93%, inverted Sugars 18.56%, sucrose 5.99%, pentosans 8.92%, vitamin P, including quartzetine and isocvercitin 4%, anthocyanins 45mg%.
  • Buckwheat groats vitamin P, including quartzetin8%.
  • both rosehip and buckwheat products contain more than half of the recommended by the inventors to block the cancer process at all stages of its development and restore immunity.
  • the concentration of biologically active compounds and vitamins in dogrose and buckwheat is more than three times higher than in the prototype.
  • the authors found that to suppress the cancer process, it is necessary to limit the intake of arachidonic acid and fatty acids into the developing tumor, and to suppress the angiogenesis of the growing tumor and apaptosis of growing cancer cells, quartzetin is needed, which is most found in rosehips and buckwheat. This is the main essence of the proposed invention.
  • the authors also offered a menu for the week.
  • the repetition of the seven-day menu for 3-6 months is due to the cyclical life of the cancerous tumor.
  • the claimed set of products is the necessary and minimum list of products that a cancer patient must consume every week during treatment. From many years of treatment experience it follows that the long-term use of a limited range of products is very tiring for the patient and not all patients cope with this, even if they mobilize all their willpower and desire to overcome a serious illness.
  • the authors offer additional, optional products that will only facilitate the systematic long-term adoption of a limited, uniform list of products for the patient.
  • the proposed weekly menu is as follows.
  • porridge is prepared from one tablespoon of rosehip flour. To do this, 100 grams of rose hips need to grind in a coffee grinder to a fine flour, sift. Grind the leftovers in a mortar and mix with the main flour. Take one tablespoon of the resulting mixture, dilute with cold boiled water to the consistency of liquid porridge. Add one dessert spoon of flower honey to the obtained porridge. Eat slowly.
  • Soup a cup of beans, chop 1 head of onion, 2 stalks of celery, 3 carrots, add 2 tablespoons of olive oil and 4 glasses of water. Cook for 30 minutes.
  • the second dish salmon fish.
  • Method of preparation 100-150 grams of fish, 2 stalks of asparagus, 2 small tomatoes, 4-5 shitaki mushrooms, 5 grapes without grains, 3 tablespoons of vegetable oil, a teaspoon of lemon juice, 1 garlic clove, dill, fresh green pepper. Cook in a deep skillet over low heat for 15 minutes.
  • Second course chickens (preferably not incubator) with ginger and onions.
  • Method of preparation 200 grams of chicken without skin, cut 2 large onions and 1 tomato, 2 tablespoons of vegetable oil, a tablespoon of white wine, a teaspoon of fresh ginger, 2 tablespoons of orange juice, a teaspoon of grated orange peel, a cup of grapes without grains.
  • the second dish any vegetarian dishes. Bread 150-200 grams from wholemeal flour. On the third, any natural juices, freshly prepared, sugar free 200-250 grams.
  • Stewed vegetables for vegetarian days medium-sized beets, 2 carrots, 100 grams of broccoli, 100 grams of Brussels sprouts, 100 grams of cauliflower, 1 capsicum, 1 tablespoon of olive oil. Cut and stew vegetables for 30 minutes. The ratio of the number of vegetables consumed to the number of fish or chicken should be 3: 1.
  • the table shows the products, their weight and calories needed by the cancer patient for a week.
  • Example 1 Patient 34 years. Diagnosis: Cancer of the left breast gland Stage III TZN1M0, the state after radical mastectomy and radiotherapy in 1972. The patient underwent chemotherapy according to the standard CMF regimen (cyclophosphamide + metectrate + 5ftopyracil) on the background of a 100% cereal diet, which the patient maintained for three years. In the future, the complete exclusion of sugar, salt, animal proteins. Salts are not more than 0.5 grams per day. Last survey in 1998: no data for relapse and metastasis.
  • Example 2 Patient 38 years. Diagnosis: Cancer of the right breast IV Art. T 2 NlMl. Cancer metastases to the lung. The patient was transferred to a 100% cereal diet, twice a day in the morning before breakfast and in the afternoon before meals - liquid porridge from brown (May) rosehip flour. The patient underwent three courses of chemotherapy according to the standard ACMF regimen (adriablastin + cyclophosphamide + methotrexate + 5ftopyracil). Three months later, during a follow-up examination, lung metastases were not detected.
  • Example 3 Patient 37 years. Diagnosis: Cancer of the right mammary gland 116 tbsp. T2 Nl MO. Radical mastectomy, postoperative radiation therapy and 6 courses of chemotherapy according to the CMF scheme. After 3 years, cancer metastases to the liver. The liver is three transverse fingers below the edge of the costal arch. The patient was transferred to a 100% cereal diet, twice a day - porridge from dogrose flour. On day 25, the liver contracted to normal size. Later, the patient developed cirrhosis of the liver, as a result of which the patient died. At autopsy, liver metastases were not detected.
  • Example 4 Patient 63 years. Diagnosis: Cancer of the right breast T2 Nl MO. Comprehensive treatment. After 9 years, metastases in the 12 thoracic vertebra with compression fracture and compression of the spinal cord, flaccid paralysis of both lower extremities. The patient was assigned a 100% cereal diet and a forced position on his back on a wooden shield. After 6 weeks, the patient stood on crutches and went. The last visit to the sick doctor was a year later, the patient on her own on public transport, leaning on a stick, came to the doctor for an appointment.
  • Example 5 Patient 15 years. Diagnosis: Lymphogranulomatosis with lesions of the lymph nodes above and below the diaphragm. 6 chemotherapy courses at the VSC was ineffective - there was an increase in lymph nodes. The patient was transferred to a 100% cereal diet, against the background of which chemotherapy was carried out according to the CORR-b scheme. At 100% cereal diet, the patient was 24 weeks. A year later, the patient got married, gave birth to two daughters. The last examination after 15 years of data for the recurrence of lymphogranulomatosis was not.
  • Example 6 The patient is 19 years old. Diagnosis: Lymphogranulomatosis, stage IV, damage to the lymph nodes above and below the diaphragm, liver damage. Ascites. Against the background of a 100% cereal diet, the patient was given 6 courses of COPP. After the first 2 courses of COPP against the background of a 100% cereal diet, ascites was not determined, the lymph nodes of the neck decreased. The patient graduated from high school, the Institute of Communications. He went to work in one of the banks. Errors in the diet began. As soon as the patient switched to the general table, relapse occurred. Treatment all the traditional methods of chemotherapy at the Hematology Center AM Russia was not effective.
  • Example 7 Patient 50 years. Diagnosis: Lymphosarcoma with the defeat of feather plaques stage 111 tbsp. The symptom of the disease was expressed in frequent, up to 24 times a day, loose stool. After transferring the patient to a 100% cereal diet, on day 5, the stool became 3 times a day. The patient noted that when switching to a common table, the chair immediately became more frequent.
  • Example 8 The patient is 40 years old. Diagnosis: Lymphosarcoma of the stomach and mesenteric lymph nodes soldered together in a single conglomerate with a diameter of up to 20 cm stage IV art. The patient was transferred to a 100% cereal diet and 6 courses of ACOP chemotherapy were performed (Adriamycin + Cyclophosphamide + Vincristine + Procarbazine). The tumor is no longer being determined. The patient strictly adhered to the cereal diet for 2.5 years. The last examination at the oncological institute did not reveal a relapse of lymphosarcoma.
  • Example 9 Patient 72 years. Diagnosis: Ovarian cancer T2N1M1, peritoneal metastases, ascites.
  • ACOP Adriamycin + Cyclophosphamide + Vincristine + Procarbazine
  • Example 10. Patient 58 years old. Diagnosis: Prostate cancer T2N1M1 with metastases in the pelvic bone, with germination in the urethra. The patient has severe pain during urination. When transferring the patient to a 100% cereal diet and rosehip porridge, the pain syndrome stopped after 7 days. The patient was given 4 courses of ACOP. The patient lived without pain for 3 years.
  • Diagnosis Lymphogranulomatosis with damage to all groups of peripheral lymph nodes stage 1 V st. The last three months the patient in the evening, the temperature rose to 39.5-40.5 degrees. When transferring the patient to a 100% cereal diet and rosehip porridge, the temperature on the 5th day returned to normal. After three weeks, the peripheral lymph nodes decreased significantly. The patient stayed on the proposed diet for 3 months. Considering himself healthy, despite the doctor’s warnings, he switched to the general table. Rapid relapse occurred on the third day of the general table, the patient died after 3 weeks.
  • Example 12 Patient 32 years. Cancer of the right breast T2N1M0. Operation radical mastectomy, chemotherapy 6 courses of CMF (cyclophosphamide + methotrexate + 5 fluorouracil) and radiation therapy. Two years after the last course of chemotherapy, the patient developed jaundice; liver scans revealed liver metastases. The patient was transferred to a 100% cereal diet and started treatment with microclysters of horseradish infusion every other day for a month, with a control scan of the liver metastases were not detected. Six months later, stress - a divorce from her husband, relapse of liver metastases.
  • CMF cyclophosphamide + methotrexate + 5 fluorouracil
  • Example 13 The patient is 77 years old. Skin cancer of the right lower leg T2N0M0, the operation is a wide excision of the tumor. Two years later, cancer metastases in the right inguinal and left axillary regions. A cytological examination revealed metastases of a malignant neuroepithelial tumor (Merkell cellulitis). Sick US citizen. Lives in New York. After the first course of chemotherapy (Adriamycin - Taxol) metastases remained unchanged. The patient was transferred to a cereal diet. Three weeks after the appointment of the diet, a second course of the same chemotherapy was carried out. Two months after the examination of the patient, when the above metastases were revealed and 5 weeks after chemotherapy, when examining the patient, metastases were not detected in the right inguinal region or in the left axillary.
  • the proposed set for weekly dietary nutrition unlike many therapeutic drugs used to treat oncology and which are highly specialized, provides suppression of any types of oncology at all stages of tumor development due to restoration of the normal functioning of the complex in which the P-53 gene is located.
  • the use of products containing them instead of vitamins directly also allows you to gently affect the body, restore impaired immunity without side effects, expand the range of pharmacological effects, and increase the effectiveness of chemotherapy.
  • the proposed set of products in addition to the identified effective therapeutic effects, can be used for prevention and prevention oncological diseases.
  • Organized diet food based on the proposed set of products, can be recommended for centenarians.

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Abstract

L'invention concerne la médecine. Un ensemble d'aliments pour un régime hebdomadaire destiné aux patients oncologiques et aux personnes ayant une durée de vie remarquablement longue comprend les aliments utilisés dans des proportions suivantes, en grammes : farine de cynorrhodon 205-210, farine de sarrasin 340-350, son 65-70, thé vert 32-35, pain de farine grossière 980-1000, fèves 190-200, lentilles 190-200, champignons frais shiitake ou mantaki 290-300 ou séchés 145-150, saumon frais 290-300, poulet non élevé en batterie 140-150, oignon 190-200, ail 90-95, carottes 1450-1500, tomates1450-1500, choux blanc 450-500, choux de Bruxelles 450-500, chou-fleur 450-500, brocoli 290-300, betterave rouge 470-500, poivrons rouges, verts ou jaunes 340-350, céleri 18-20, aneth 18-20, persil 18-20, myrtilles 380-400, raisin 380-400, ananas 2600-2700, papaye 2400-2450, citron 240-250, orange 260-270 et huile d'olive 340-350.
PCT/RU2006/000340 2006-06-29 2006-06-29 Régime hebdomadaire destiné aux patients oncologiques et aux personnes ayant une durée de vie remarquablement longue Ceased WO2008002175A1 (fr)

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CN101669651B (zh) * 2009-09-23 2013-03-20 青岛浩源集团有限公司 一种三文鱼蔬菜圈的制备工艺
JP2015523366A (ja) * 2012-07-05 2015-08-13 ニュートラマックス ラボラトリーズ，インコーポレイテッド スルホラファンまたはスルホラファン前駆体およびキノコ抽出物または粉末を含む組成物

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RU2044547C1 (ru) * 1993-11-18 1995-09-27 Леонид Петрович Бурага Средство для профилактики и лечения злокачественных новообразований
RU2136324C1 (ru) * 1998-03-20 1999-09-10 Антоненко Надежда Николаевна Способ коррекции статуса больных с онкозаболеваниями по методу антоненко
UA41000A (fr) * 2000-12-26 2001-08-15
RU2218169C2 (ru) * 2002-01-30 2003-12-10 Савватеев Евгений Витальевич Комплексный способ химиолучевой и диетотерапии при лечении онкологических заболеваний

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RU2044547C1 (ru) * 1993-11-18 1995-09-27 Леонид Петрович Бурага Средство для профилактики и лечения злокачественных новообразований
RU2136324C1 (ru) * 1998-03-20 1999-09-10 Антоненко Надежда Николаевна Способ коррекции статуса больных с онкозаболеваниями по методу антоненко
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RU2218169C2 (ru) * 2002-01-30 2003-12-10 Савватеев Евгений Витальевич Комплексный способ химиолучевой и диетотерапии при лечении онкологических заболеваний

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Publication number Priority date Publication date Assignee Title
CN101669651B (zh) * 2009-09-23 2013-03-20 青岛浩源集团有限公司 一种三文鱼蔬菜圈的制备工艺
JP2015523366A (ja) * 2012-07-05 2015-08-13 ニュートラマックス ラボラトリーズ，インコーポレイテッド スルホラファンまたはスルホラファン前駆体およびキノコ抽出物または粉末を含む組成物
US11654186B2 (en) 2012-07-05 2023-05-23 Nutramax Laboratories, Inc. Compositions comprising sulforaphane or a sulforaphane precursor and a mushroom extract or powder
US12064471B2 (en) 2012-07-05 2024-08-20 Nutramax Laboratories, Inc. Compositions comprising sulforaphane or a sulforaphane precursor and a mushroom extract or powder

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