[go: up one dir, main page]

WO2008000186A8 - A method for identifying novel gene and the resulting novel genes - Google Patents

A method for identifying novel gene and the resulting novel genes Download PDF

Info

Publication number
WO2008000186A8
WO2008000186A8 PCT/CN2007/070153 CN2007070153W WO2008000186A8 WO 2008000186 A8 WO2008000186 A8 WO 2008000186A8 CN 2007070153 W CN2007070153 W CN 2007070153W WO 2008000186 A8 WO2008000186 A8 WO 2008000186A8
Authority
WO
WIPO (PCT)
Prior art keywords
genes
novel
human
identifying
gene
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Ceased
Application number
PCT/CN2007/070153
Other languages
French (fr)
Chinese (zh)
Other versions
WO2008000186A1 (en
Inventor
Zailin Yu
Zhihua Zheng
Y Tom Tang
Fu Genny Yan Yu
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Tianjin Sinobiotech Ltd
Fortunerock Inc
Original Assignee
Tianjin Sinobiotech Ltd
Fortunerock Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Tianjin Sinobiotech Ltd, Fortunerock Inc filed Critical Tianjin Sinobiotech Ltd
Priority to CNA2007800202904A priority Critical patent/CN101460625A/en
Publication of WO2008000186A1 publication Critical patent/WO2008000186A1/en
Anticipated expiration legal-status Critical
Publication of WO2008000186A8 publication Critical patent/WO2008000186A8/en
Ceased legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/775—Apolipopeptides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6876—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
    • C12Q1/6883—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/92—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving lipids, e.g. cholesterol, lipoproteins, or their receptors
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00—Oligonucleotides characterized by their use
    • C12Q2600/156—Polymorphic or mutational markers

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Organic Chemistry (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Analytical Chemistry (AREA)
  • Biophysics (AREA)
  • Zoology (AREA)
  • Genetics & Genomics (AREA)
  • Immunology (AREA)
  • Biochemistry (AREA)
  • Biotechnology (AREA)
  • Biomedical Technology (AREA)
  • Microbiology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Urology & Nephrology (AREA)
  • Physics & Mathematics (AREA)
  • Hematology (AREA)
  • Wood Science & Technology (AREA)
  • Pathology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Cell Biology (AREA)
  • Toxicology (AREA)
  • General Engineering & Computer Science (AREA)
  • Food Science & Technology (AREA)
  • General Physics & Mathematics (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Endocrinology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)

Abstract

The present invention discloses a method for identifying novel gene using bioinformatics analyses, computer simulation forecasting technique and molecular biological technique. In particular, using human genome sequence data, a computer analysis and forecast means are obtained by self-programming and analyses. And thus a series of novel genes are identified and preparated. These new genes, which are designed as BFC06016 and BFC06104, are similar to human apolioprotein AIBP, and their accession numbers in GenBank are DQ778079 and DQ778080, respectively. The genes and its encoded proteins are possible to be related to the metabolism in body ofcholesterol, and can be used as the candidate targets of medicaments in the diagnoses and treatment of human cardiovascular disease.
PCT/CN2007/070153 2006-06-21 2007-06-21 A method for identifying novel gene and the resulting novel genes Ceased WO2008000186A1 (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
CNA2007800202904A CN101460625A (en) 2006-06-21 2007-06-21 Method for discovering novel gene and discovered novel gene

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
CN200610089339.9 2006-06-21
CNA2006100893399A CN1884521A (en) 2006-06-21 2006-06-21 Method for finding novel gene and computer system platform using same and novel gene

Publications (2)

Publication Number Publication Date
WO2008000186A1 WO2008000186A1 (en) 2008-01-03
WO2008000186A8 true WO2008000186A8 (en) 2009-07-09

Family

ID=37582826

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/CN2007/070153 Ceased WO2008000186A1 (en) 2006-06-21 2007-06-21 A method for identifying novel gene and the resulting novel genes

Country Status (2)

Country Link
CN (2) CN1884521A (en)
WO (1) WO2008000186A1 (en)

Families Citing this family (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1884521A (en) * 2006-06-21 2006-12-27 北京未名福源基因药物研究中心有限公司 Method for finding novel gene and computer system platform using same and novel gene
CN101930502B (en) * 2010-09-03 2011-12-21 深圳华大基因科技有限公司 Method and system for detection of phenotype genes and analysis of biological information
CN103186716B (en) * 2011-12-29 2017-02-08 上海生物信息技术研究中心 Metagenomics-based unknown pathogeny rapid identification system and analysis method
CN105095623B (en) * 2014-05-13 2017-11-17 中国人民解放军总医院 Screening assays, platform, server and the system of disease biomarkers
CN110019155B (en) * 2017-09-30 2023-04-07 山西医科大学 MicroRNA omics data perturbation platform
CA3100607A1 (en) * 2018-05-23 2019-11-28 Envisagenics, Inc. Systems and methods for analysis of alternative splicing
US20210225455A1 (en) * 2018-08-15 2021-07-22 Zymergen Inc. Bioreachable prediction tool with biological sequence selection
EP3867400A4 (en) * 2018-10-17 2022-07-27 Quest Diagnostics Investments LLC GENOMIC SEQUENCING SELECTION SYSTEM
CN110033826B (en) * 2018-12-10 2023-08-08 上海派森诺生物科技股份有限公司 Analysis method applied to macrovirome high-throughput sequencing data
CN109785900B (en) * 2018-12-12 2023-05-23 上海派森诺生物科技股份有限公司 Microbial community functional gene analysis method based on protein sequence similarity
CN111199772B (en) * 2019-12-27 2023-05-23 上海派森诺生物科技股份有限公司 PEDV (porcine reproductive and respiratory syndrome Virus) genome analysis method based on second-generation sequencing
JP7435821B2 (en) * 2020-11-12 2024-02-21 日本電信電話株式会社 Learning device, psychological state sequence prediction device, learning method, psychological state sequence prediction method, and program
CN112750501B (en) * 2020-12-29 2024-04-02 上海派森诺生物科技股份有限公司 Optimized analysis method for macro virus group flow
CN119832988B (en) * 2024-12-23 2025-10-28 济南迪杰信息技术有限公司 A method and system for predicting biological reagent function

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6633819B2 (en) * 1999-04-15 2003-10-14 The Trustees Of Columbia University In The City Of New York Gene discovery through comparisons of networks of structural and functional relationships among known genes and proteins
JP2004086568A (en) * 2002-08-27 2004-03-18 Hitachi Ltd Method and program for producing novel gene
CN1884521A (en) * 2006-06-21 2006-12-27 北京未名福源基因药物研究中心有限公司 Method for finding novel gene and computer system platform using same and novel gene

Also Published As

Publication number Publication date
CN101460625A (en) 2009-06-17
WO2008000186A1 (en) 2008-01-03
CN1884521A (en) 2006-12-27

Similar Documents

Publication Publication Date Title
WO2008000186A8 (en) A method for identifying novel gene and the resulting novel genes
Semenova et al. Genes and athletic performance: the 2023 update
Liu et al. Applying DNA barcodes for identification of plant species in the family Araliaceae
Ren et al. Widespread whole genome duplications contribute to genome complexity and species diversity in angiosperms
Hasin et al. Multi-omics approaches to disease
Bulgarelli et al. Structure and function of the bacterial root microbiota in wild and domesticated barley
Braconi et al. Foodomics for human health: current status and perspectives
EP2718862B1 (en) Method for assembly of nucleic acid sequence data
Gosalbes et al. Metagenomics of human microbiome: beyond 16s rDNA
Esposito et al. Bioinformatics for agriculture in the next-generation sequencing era
Han et al. SSR marker development and intraspecific genetic divergence exploration of Chrysanthemum indicum based on transcriptome analysis
Jiang et al. De novo assembly and characterization of the transcriptome, and development of SSR markers in wax gourd (Benicasa hispida)
Brozynska et al. Chloroplast genome of novel rice germplasm identified in northern Australia
Chen et al. Characterization of the Lycium barbarum fruit transcriptome and development of EST-SSR markers
WO2009009752A3 (en) Genetic models for stratification of cancer risk
WO2007054520A3 (en) Methods for the identification of microrna and their applications in research and human health
Zhang et al. Differential transcriptome analysis between Paulownia fortunei and its synthesized autopolyploid
De Paolo et al. De novo transcriptome assembly from inflorescence of Orchis italica: analysis of coding and non-coding transcripts
Ye et al. Phylogeographic analyses strongly suggest cryptic speciation in the giant spiny frog (Dicroglossidae: Paa spinosa) and interspecies hybridization in Paa
Biswas et al. Genome-wide novel genic microsatellite marker resource development and validation for genetic diversity and population structure analysis of banana
Goto-Yamamoto et al. Genetic analysis of East Asian grape cultivars suggests hybridization with wild Vitis
Suo et al. A new nuclear DNA marker from ubiquitin ligase gene region for genetic diversity detection of walnut germplasm resources
An et al. Genome survey sequencing of Luffa Cylindrica L. and microsatellite high resolution melting (SSR-HRM) analysis for genetic relationship of Luffa genotypes
Alzahrani Complete chloroplast genome of Abutilon fruticosum: genome structure, comparative and phylogenetic analysis
Rudić et al. In Silico study of superoxide dismutase gene family in potato and effects of elevated temperature and salicylic acid on gene expression

Legal Events

Date Code Title Description
WWE Wipo information: entry into national phase

Ref document number: 200780020290.4

Country of ref document: CN

121 Ep: the epo has been informed by wipo that ep was designated in this application

Ref document number: 07721771

Country of ref document: EP

Kind code of ref document: A1

NENP Non-entry into the national phase in:

Ref country code: DE

NENP Non-entry into the national phase in:

Ref country code: RU

122 Ep: pct application non-entry in european phase

Ref document number: 07721771

Country of ref document: EP

Kind code of ref document: A1