[go: up one dir, main page]

WO2008094507A3 - Novel fusion compounds - Google Patents

Novel fusion compounds Download PDF

Info

Publication number
WO2008094507A3
WO2008094507A3 PCT/US2008/001092 US2008001092W WO2008094507A3 WO 2008094507 A3 WO2008094507 A3 WO 2008094507A3 US 2008001092 W US2008001092 W US 2008001092W WO 2008094507 A3 WO2008094507 A3 WO 2008094507A3
Authority
WO
WIPO (PCT)
Prior art keywords
novel fusion
fusion compounds
compounds
compositions
management
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Ceased
Application number
PCT/US2008/001092
Other languages
French (fr)
Other versions
WO2008094507A2 (en
Inventor
Tsvetelina Lazarova
Michael Thormann
Michael Almstetter
Guillaume Cottarel
Steven Wayne Riesinger
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Cellicon Biotechnologies Inc
Original Assignee
Cellicon Biotechnologies Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Cellicon Biotechnologies Inc filed Critical Cellicon Biotechnologies Inc
Publication of WO2008094507A2 publication Critical patent/WO2008094507A2/en
Publication of WO2008094507A3 publication Critical patent/WO2008094507A3/en
Anticipated expiration legal-status Critical
Ceased legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04—Ortho-condensed systems
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
    • C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
    • C07D405/12—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a chain containing hetero atoms as chain links
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D499/00—Heterocyclic compounds containing 4-thia-1-azabicyclo [3.2.0] heptane ring systems, i.e. compounds containing a ring system of the formula:, e.g. penicillins, penems; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
    • C07D499/21—Heterocyclic compounds containing 4-thia-1-azabicyclo [3.2.0] heptane ring systems, i.e. compounds containing a ring system of the formula:, e.g. penicillins, penems; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring with a nitrogen atom directly attached in position 6 and a carbon atom having three bonds to hetero atoms with at the most one bond to halogen, e.g. an ester or nitrile radical, directly attached in position 2
    • C07D499/44—Compounds with an amino radical acylated by carboxylic acids, attached in position 6
    • C07D499/46—Compounds with an amino radical acylated by carboxylic acids, attached in position 6 with acyclic hydrocarbon radicals or such radicals substituted by carbocyclic or heterocyclic rings, attached to the carboxamido radical
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H17/00—Compounds containing heterocyclic radicals directly attached to hetero atoms of saccharide radicals

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Biochemistry (AREA)
  • Biotechnology (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

The present invention relates to novel compounds derived from compounds having antibiotic activities. The invention further provides compositions comprising a compound of this invention and the use of such compositions in methods of treating diseases and conditions beneficially treated by anti-infective agents, particularly those relating to the management of bacterial infection.
PCT/US2008/001092 2007-01-26 2008-01-25 Novel fusion compounds Ceased WO2008094507A2 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US89798107P 2007-01-26 2007-01-26
US60/897,981 2007-01-26

Publications (2)

Publication Number Publication Date
WO2008094507A2 WO2008094507A2 (en) 2008-08-07
WO2008094507A3 true WO2008094507A3 (en) 2008-10-02

Family

ID=39674685

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/US2008/001092 Ceased WO2008094507A2 (en) 2007-01-26 2008-01-25 Novel fusion compounds

Country Status (1)

Country Link
WO (1) WO2008094507A2 (en)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA2909383C (en) 2012-04-12 2020-11-10 University Of Saskatchewan Phthalocyanine compounds useful as reca inhibitors and methods of using same
WO2014138425A1 (en) 2013-03-08 2014-09-12 Allergan, Inc. Cyclosporine a-steroid conjugates
CN105073140A (en) 2013-03-08 2015-11-18 阿勒根公司 Antibiotic conjugates directly linked to steroid drugs
MA44037B1 (en) 2016-06-06 2020-03-31 Arena Pharm Inc Beta 3 adrenergic receptor modulators useful in the treatment or prevention of disorders associated therewith
CN106565654B (en) * 2016-10-14 2018-08-31 云南中烟工业有限责任公司 A kind of novel flavone compound, Its Preparation Method And Use extracted from Bai Yun Shen
LT4069691T (en) 2019-12-06 2024-12-10 Vertex Pharmaceuticals Incorporated SUBSTITUTED TETRAHYDROFURANS AS SODIUM CHANNEL MODULATORS
MX2022011370A (en) * 2020-03-23 2022-10-07 John M H Gregg Anti-viral compounds and methods for administration thereof.
DK4347031T3 (en) 2021-06-04 2025-12-01 Vertex Pharma N-(HYDROXYALKYL-(HETERO)ARYL)-TETRAHYDROFURAN-CARBOXAMIDES AS MODULATORS OF SODIUM CHANNELS
CN114315812A (en) * 2021-12-31 2022-04-12 广西师范大学 Two alkaloid compounds derived from marine fungi and their preparation methods and their application in the preparation of anti-inflammatory drugs

Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20050119269A1 (en) * 2003-10-28 2005-06-02 Rao Yeleswarapu K. Heterocyclic compounds and methods of making and using thereof

Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20050119269A1 (en) * 2003-10-28 2005-06-02 Rao Yeleswarapu K. Heterocyclic compounds and methods of making and using thereof

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
DA SILVA ET AL.: "Biological Activity and Synthetic Metodologies for the Preparation of Fluoroquinolones, A Class of Potent Antibacterial Agents", CURRENT MEDICINAL CHEMISTRY, vol. 10, 2003, pages 21 - 39 *

Also Published As

Publication number Publication date
WO2008094507A2 (en) 2008-08-07

Similar Documents

Publication Publication Date Title
WO2008094507A3 (en) Novel fusion compounds
WO2007130655A3 (en) Phage derived antimicrobial activities
WO2007120980A3 (en) 2,4-pyrimidinediamine compounds for treating or preventing autoimmune diseases
TW200716519A (en) Benzoyl-substituted serineamides
WO2008051416A3 (en) Compounds that inhibit the activity of hsp90 for treating infections
WO2010063996A3 (en) Antibacterial compounds
WO2008115281A3 (en) Compounds for treating viral infections
WO2010090860A3 (en) Methods and compositions for treating bacterial infection
UA95644C2 (en) Pyridizinone derivative, pharmaceutical composition and treatment method
TW200716558A (en) Heteroaroyl-substituted serineamides
WO2008073933A3 (en) 4-phenyl-6-(2,2,2-trifluoro-1-phenylethoxy)pyrimidine-based compounds and methods of their use
WO2007092622A3 (en) Compositions and methods for treating bone
TNSN07383A1 (en) 1-h-quinazoline-2,4-diones and their use as ampa-receptor ligands
WO2011005341A3 (en) Compositions and methods related to protein a (spa) variants
WO2010053573A3 (en) Screen for inhibitors of filovirus and uses therefor
WO2009026166A3 (en) Antiinfective flavonol compounds and methods of use thereof
WO2007085852A3 (en) Antimicrobial materials
WO2010151784A3 (en) Antimicrobial compounds
WO2007109105A3 (en) Flavivirus inhibition by sultams and related compounds
WO2007109279A3 (en) Tetrahydropyridothienopyrimidine compounds and methods of use thereof
WO2008133734A3 (en) Method and compositions for treating hiv infections
WO2007097981A3 (en) Alpha carbolines and uses thereof
WO2010032011A8 (en) Anti-fungal therapy
WO2007117680A3 (en) Methods and compositions for treating bacterial infection
WO2007067416A3 (en) Heterocyclylacrylamide compounds as fabi inhibitors and antibacterial agents

Legal Events

Date Code Title Description
NENP Non-entry into the national phase

Ref country code: DE

121 Ep: the epo has been informed by wipo that ep was designated in this application

Ref document number: 08724872

Country of ref document: EP

Kind code of ref document: A2

122 Ep: pct application non-entry in european phase

Ref document number: 08724872

Country of ref document: EP

Kind code of ref document: A2