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WO2008091265A1 - Procédés à volumes élevés et alternatifs de distribution de remèdes homéopathiques - Google Patents

Procédés à volumes élevés et alternatifs de distribution de remèdes homéopathiques Download PDF

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Publication number
WO2008091265A1
WO2008091265A1 PCT/US2007/002462 US2007002462W WO2008091265A1 WO 2008091265 A1 WO2008091265 A1 WO 2008091265A1 US 2007002462 W US2007002462 W US 2007002462W WO 2008091265 A1 WO2008091265 A1 WO 2008091265A1
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WO
WIPO (PCT)
Prior art keywords
homeopathic
delivery
regions
remedy
remedies
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Ceased
Application number
PCT/US2007/002462
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English (en)
Inventor
Floyd Taub
Char Tara Albert
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Individual
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Individual
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Priority to PCT/US2007/002462 priority Critical patent/WO2008091265A1/fr
Publication of WO2008091265A1 publication Critical patent/WO2008091265A1/fr
Anticipated expiration legal-status Critical
Ceased legal-status Critical Current

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Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0087—Galenical forms not covered by A61K9/02 - A61K9/7023
    • A61K9/0095—Drinks; Beverages; Syrups; Compositions for reconstitution thereof, e.g. powders or tablets to be dispersed in a glass of water; Veterinary drenches

Definitions

  • This invention relates to alternative methods of delivering homeopathic remedies/ especially of high volume homeopathic remedies.
  • the current accepted method of delivering homeopathic remedies designed for systemic effects is sub-lingual administration and/or small portions. (Salves or gels are also used for local administration.)
  • Sublingual administration either in the form of small amounts of liquid tinctures or pellets or lozenges that dissolve in the mouth is extensively described.
  • a homeopathic remedy delivered to these sites has excellent potential to almost immediately interact with lymphoid cells (or other cells, especially glandular and absorptive gastro intestinal cells) and to start a cascade of events leading to a decrease in disease or alteration of physiologic state.
  • the liver may also alter a prodrug to a metabolically active form (or relatively confine a relatively toxic prodrug to the portal circulation) so this first pass through the liver may be very important; upon being picked up by the blood stream, the mesenchymal and portal circulations first deliver the absorbed materials to the liver and spleen which are extraordinarily important to immune function.
  • this invention allows more. direct and specific delivery to mesenteric lymph nodes, liver and spleen.
  • liver and spleen are two of the largest immunologic organs in the body.
  • the liver has numerous detoxification and synthetic functions that are essential for optimizing health and curing disease; an initial "first" pass through these organs is likely to optimize the bioactivity.
  • homeopathic products especially these homeopathic products, may be taken without the need for special "clean" mouth,. (or limiting food and water intake, or restricting foods previously restricted, especially certain agents like mints-flavor which were especially forbidden) , and 3. distal delivery may be more advantageous in some situations.
  • Vaginal and anal suppositories have been used but generally not as hor ⁇ eopathics, even if some examples of "homeopathic" uses exist, the homeopathic suppositories still tended to be of small volumes. It is also significant that the blood flow to these regions is different from the blood flow to the stomach, the small intestinal tract and even the large intestinal tract because it is not the same as the blood flow to the portal system.
  • Anal and especially vaginal suppositories are more equivalent to local skin salves used heretofore than 1. to a systemic or 2. to a stomach or 3. to an intestinal method of administering homeopathic medicines as described in the instant application.
  • MALT Mucosal Associated Lymphocytic Tissues
  • the homeopathic (s) may be in the form of suspensions, solutions, tablets, capsules (with coatings of various types) , lipid containing capsules or micelles, or microspheres, or microspheres or bukeyballs or any other pharmaceutical delivery devices or carriers now known in the standard pharmaceuticals literature or developed for the future.
  • the blood from the intestines flows through the mesemchymal circulation to the liver and to the spleen which are major immunological organs containing a variety of immune sells. (See Paul, "Fundamentals of Immunology,” incorporated herein by reference.)
  • all of the aforementioned regions of the body with MALTs are within the scope of this invention.
  • the homeopathic material may be mixed with other ingredients known in the pharmaceutical or nutraceutical practice now known or as known n the future to facilitate penetration or increase the efficacy and safety of the homeopathic drug or to complement the benefit .
  • Delivery by this method has distinct advantages when the disease to be treated may be located more distally to the oropharynx, especially ' in the alimentary tract such as inflammatory bowel disease, Crohn's Disease, proliferative diseases, inflammatory diseases, ulcerative diseases, atrophic diseases or other ailments of tissue in the region of the MALT or directly to the diseases of the mucosal tissues .
  • Another embodiment of this invention resides in the use of the gut associate MALT to absorb the homeopathic remedy for delivery to organs which receive portal circulation and also to the systemic organs to which the circulation ultimately goes, for example, following metabolic conversion in the liver before reaching the general circulation.
  • This invention applies equally to home ⁇ pathics at low and high potencies from Ix to 500 Million.
  • a common use might be locally made (by a person or soda fountain type machine) or especially prepackaged drinks containing volumes from 1/2 cup to . hundreds of gallons. Typically prepackaged drinks would be sold to the consumer in volumes of 1/2 cup to 5 gallons. These might be labeled, for example, to alleviate fatigue, improve concentration, increase endurance or, without limitation, any of the other indications for any ailment for which any homeopathic remedy treats or prevents. These are listed in compendium of materia medica and incorporated herein by- reference. A specific example is including in water homeopathic reagents known to stimulate the immune system and/or relieve fatigue.
  • homeopathic remedies examples include , Taurox SBTM, Tauroxicum, COBAT, all the products listed in the HPUS (Homeopathic Pharmacopeias of the United States) , pharmacopeias of Germany or France or other agents which become so listed or otherwise established as homeopathic remedies ex HCUS. They also include those in homeopathic pharmacopeias of other countries and other medicines designated as homeopathic. (All these Pharmacopeias are included by reference in his application.) Other common homeopathic ingredients include aloe; armica; cactus; Licopodium and calceolaria.
  • the invention applies equally to all types of body cells including ectodermal, mesodermal or endodermal derived cells. It also applies to all types of immune cells which may be of special relevance and which are known in the art and for instance mentioned in Dr. Paula's Fundamentals of Immunology and numerous other standard texts in the appropriate fields. It also applies to neural cells which are closely related to the immune system (The Neuro-Immunologic System ⁇ and are known in the art and for instance mentioned in Neurology. These include but are not limited to B. T r NK, macrophage, APC, kioller, endothelial, fibroblastic, astrocytic cells and cells that support and aid the growth of these cells. EXAMPLES :
  • Example 1 shows effectiveness when included in juice .
  • work was commenced experimenting with preparations designed to provide delivery of the homeopathic medicine to internal regions.
  • dilution in a liquid for example, orange " juice, other juices or water and swallowing the dilution, resulting in delivery to the stomach and more distal digestive organs, was similarly effective as sublingual and much more palatable and convenient for certain persons such as, for instance, teenagers.
  • the presence of a wide variety of chemicals including acids and strong fruit flavors did not prevent the action of the homeopathic.
  • the homeopathic remedy may be included in food .
  • Misty a cat who had been accepted by a rescue shelter, suffered with severe, potentially life-threatening Gran MaI seizures about three times a day and almost every other day. She was tried on a variety of herbal medications and on Bromide salts without significant benefits. Taurox SBTM was added to her food, and she promptly stopped having seizures. She has not had a seizure for 27 days. Overall, she averaged a few a month while being treated.
  • T.C a 42 -year old woman with Sickle Cell Anemia, reports that swallowing Taurox SBTM in a glass of water (15 drops Integra THTM) reduces the fatigue and pain of her disease.
  • the medication may be included, for example, in water or juice.
  • Example 1 shows the effectiveness when included in juice.
  • it may also be included in water, sports drinks, pleasure drinks, including alcoholic and non-alcoholic drinks, slurries, gels or foods, which are all possible.
  • the homeopathic remedy may also be included in food. Misty had a history of Gran MaI seizures three times a day, almost every day. Since including Taurox SBTM in her food she had not had a seizure for 27 days.
  • This invention applies to all foods from treats treated with the homeopathic on site, to the bulk supplied food while making it, to massive watering systems used to water livestock or irrigate fields. It applies to all forms of life including human, animal and plant. From these examples, it can be clearly appreciated that these homeopathic drugs are effective when taken diluted in large volumes of a variety of solutes or solutions. The- level of effectiveness and the exact range of effects may vary. The solute is expected to slow absorption and may have a relatively minor (less than Ix) effect on the apparent concentration.
  • the homeopathic may be mixed in water, carbonated water juices of various types or any liquid or semi-liquid or solid material. It may also be in a multicomponenet material such as a micelle, micro-sphere or other material. It may be coated with special materials well known in the pharmaceutical art to limit absorption in the upper GI tract and target absorption to the intestines or lower GI tract which may be in need of therapy in a variety of diseases including Crohn's Disease, Ulcerative Colitis, cancer and inflammatory and infectious problems. Targeting to any organ or region in the body may be achieved with antibodies or specific binding materials.
  • Various doses may be used as known in the homeopathy art from Ix to 200M.
  • the most preferred embodiments are 3x to 2Ox and especially 5x to 10x.
  • ETor some preparations it has bee beneficial to encapsulate the drug in capsule, or compact the same into a pill, to facilitate the task of carrying and administration, especially if it is being co-administered with a variety of nutraceuticals or pharmaceutical materials best, most commonly, or most conveniently given in a pill or capsule form.
  • Administration in large volume of water, sports drink, mineral or nutrient-containing water or other drink may be especially advantageous as it spreads out the administration over the period of time as the drink is consumed.
  • Taurox SBTM in a variety of methods may decrease pain and damage due to sickle cell anemia, arteriole or artery blockage and pulmonary hypertension when given in a variety of doses and dose forms. Treatment of Sickle Cell Anemia with Taurox SBTM is thus another discovery that is part of this invention.
  • the invention although illustrated for Taurox SBTM, applies to all homeopathic remedies whether used as single agents of mixtures, regardless of their function.
  • cold remedies remedies for fatigue such as the Dolisos product
  • remedies for flu and any other types may be given in this larger form. This is in stark contrast to previous teachings of both low volume and the need described in homeopathic texts to limit the intake of other materials within a period of time before or after the taking of the homeopathic.

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  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

L'invention concerne un procédé alternatif de distribution de médicaments homéopathiques par ciblage de l'administration au système lymphoïde des muqueuses, notamment du tractus intestinal et dans des volumes élevés.
PCT/US2007/002462 2007-01-26 2007-01-26 Procédés à volumes élevés et alternatifs de distribution de remèdes homéopathiques Ceased WO2008091265A1 (fr)

Priority Applications (1)

Application Number Priority Date Filing Date Title
PCT/US2007/002462 WO2008091265A1 (fr) 2007-01-26 2007-01-26 Procédés à volumes élevés et alternatifs de distribution de remèdes homéopathiques

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
PCT/US2007/002462 WO2008091265A1 (fr) 2007-01-26 2007-01-26 Procédés à volumes élevés et alternatifs de distribution de remèdes homéopathiques

Publications (1)

Publication Number Publication Date
WO2008091265A1 true WO2008091265A1 (fr) 2008-07-31

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Family Applications (1)

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PCT/US2007/002462 Ceased WO2008091265A1 (fr) 2007-01-26 2007-01-26 Procédés à volumes élevés et alternatifs de distribution de remèdes homéopathiques

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Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20040019107A1 (en) * 2002-07-29 2004-01-29 Floyd Taub Homeopathic drug composition and methods of use thereof
US20040086579A1 (en) * 2002-11-05 2004-05-06 Higgins James W. Dietary supplement comprising parthenolide
US20040247744A1 (en) * 2002-02-11 2004-12-09 Edizone, Lc Vitamin-containing orally soluble films

Patent Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20040247744A1 (en) * 2002-02-11 2004-12-09 Edizone, Lc Vitamin-containing orally soluble films
US20040019107A1 (en) * 2002-07-29 2004-01-29 Floyd Taub Homeopathic drug composition and methods of use thereof
US20040086579A1 (en) * 2002-11-05 2004-05-06 Higgins James W. Dietary supplement comprising parthenolide

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