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WO2008075169A3 - Procédé de purification de chlorhydrate de ropinirole - Google Patents

Procédé de purification de chlorhydrate de ropinirole Download PDF

Info

Publication number
WO2008075169A3
WO2008075169A3 PCT/IB2007/003914 IB2007003914W WO2008075169A3 WO 2008075169 A3 WO2008075169 A3 WO 2008075169A3 IB 2007003914 W IB2007003914 W IB 2007003914W WO 2008075169 A3 WO2008075169 A3 WO 2008075169A3
Authority
WO
WIPO (PCT)
Prior art keywords
purification
ropinirole hydrochloride
ropinirole
hydrochloride
formula
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Ceased
Application number
PCT/IB2007/003914
Other languages
English (en)
Other versions
WO2008075169A2 (fr
Inventor
Vijaybaskar Veerappan
Sam Daniel Prabhu Devasitham
Seshukumar Arvapally
Susi Swaminathan
Mahender Rao Siripragada
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Orchid Pharma Ltd
Original Assignee
Orchid Chemicals and Pharmaceuticals Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Orchid Chemicals and Pharmaceuticals Ltd filed Critical Orchid Chemicals and Pharmaceuticals Ltd
Publication of WO2008075169A2 publication Critical patent/WO2008075169A2/fr
Anticipated expiration legal-status Critical
Publication of WO2008075169A3 publication Critical patent/WO2008075169A3/fr
Ceased legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
    • C07D209/04—Indoles; Hydrogenated indoles
    • C07D209/30—Indoles; Hydrogenated indoles with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to carbon atoms of the hetero ring
    • C07D209/32—Oxygen atoms
    • C07D209/34—Oxygen atoms in position 2

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

La présente invention concerne un procédé de purification amélioré de chlorhydrate de Ropinirole représenté par la formule (I) utilisant un réactif contenant du phosphore.
PCT/IB2007/003914 2006-12-15 2007-12-14 Procédé de purification de chlorhydrate de ropinirole Ceased WO2008075169A2 (fr)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
IN2339/CHE/2006 2006-12-15
IN2339CH2006 2006-12-15

Publications (2)

Publication Number Publication Date
WO2008075169A2 WO2008075169A2 (fr) 2008-06-26
WO2008075169A3 true WO2008075169A3 (fr) 2011-04-28

Family

ID=39536797

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/IB2007/003914 Ceased WO2008075169A2 (fr) 2006-12-15 2007-12-14 Procédé de purification de chlorhydrate de ropinirole

Country Status (1)

Country Link
WO (1) WO2008075169A2 (fr)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN103086946B (zh) * 2013-01-17 2018-10-23 浙江华海药业股份有限公司 一种盐酸罗匹尼罗纯化的方法

Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1994015918A1 (fr) * 1993-01-08 1994-07-21 Smithkline Beecham Plc Procede de preparation de derives de l'indolone substitues
WO2005105741A1 (fr) * 2004-02-11 2005-11-10 Sun Pharmaceutical Industries Limited Hydrochlorure de 4-[2-(di-n-propylamino)ethyl]-2(3h)-indolone sensiblement pur

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1994015918A1 (fr) * 1993-01-08 1994-07-21 Smithkline Beecham Plc Procede de preparation de derives de l'indolone substitues
WO2005105741A1 (fr) * 2004-02-11 2005-11-10 Sun Pharmaceutical Industries Limited Hydrochlorure de 4-[2-(di-n-propylamino)ethyl]-2(3h)-indolone sensiblement pur

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
ANGELIQUE N.C. LOTTER ET AL.: "Synthesis of the dibenzopyrrocoline alkaloid skeleton: indolo[2,1- a]isoquinolines and related analogues.", TETRAHEDRON, vol. 63, no. 10, 5 March 2007 (2007-03-05), pages 2263 - 2274, XP005870587, DOI: doi:10.1016/j.tet.2006.12.063 *

Also Published As

Publication number Publication date
WO2008075169A2 (fr) 2008-06-26

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