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WO2008066810A3 - Pleasant tasting dry powder compositions suitable for pulmonary delivery - Google Patents

Pleasant tasting dry powder compositions suitable for pulmonary delivery Download PDF

Info

Publication number
WO2008066810A3
WO2008066810A3 PCT/US2007/024444 US2007024444W WO2008066810A3 WO 2008066810 A3 WO2008066810 A3 WO 2008066810A3 US 2007024444 W US2007024444 W US 2007024444W WO 2008066810 A3 WO2008066810 A3 WO 2008066810A3
Authority
WO
WIPO (PCT)
Prior art keywords
dry powder
pulmonary delivery
compositions suitable
powder compositions
pleasant tasting
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Ceased
Application number
PCT/US2007/024444
Other languages
French (fr)
Other versions
WO2008066810A2 (en
Inventor
Kangwen L Lin
Augustus O Okhamafe
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Novartis AG
Original Assignee
Novartis AG
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Novartis AG filed Critical Novartis AG
Publication of WO2008066810A2 publication Critical patent/WO2008066810A2/en
Publication of WO2008066810A3 publication Critical patent/WO2008066810A3/en
Anticipated expiration legal-status Critical
Ceased legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/007—Pulmonary tract; Aromatherapy
    • A61K9/0073—Sprays or powders for inhalation; Aerolised or nebulised preparations generated by other means than thermal energy
    • A61K9/0075—Sprays or powders for inhalation; Aerolised or nebulised preparations generated by other means than thermal energy for inhalation via a dry powder inhaler [DPI], e.g. comprising micronized drug mixed with lactose carrier particles

Landscapes

  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Epidemiology (AREA)
  • Pulmonology (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Otolaryngology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

This invention discloses dry powder formulations suitable for pulmonary delivery, their methods of use and methods of manufacture wherein said formulations contain at least one drug substance with particle sizes less than about 10 microns and one or more taste masking substances with particle sizes greater than about 10 microns whereby the smaller drug substance particles largely flow into the respiratory tract while the larger taste masking particles, are more limited to the tongue and the back of the throat. This particular formulation is especially suitable for dry powder formulations comprising drug substances with bad taste.
PCT/US2007/024444 2006-11-27 2007-11-27 Pleasant tasting dry powder compositions suitable for pulmonary delivery Ceased WO2008066810A2 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US86150606P 2006-11-27 2006-11-27
US60/861,506 2006-11-27

Publications (2)

Publication Number Publication Date
WO2008066810A2 WO2008066810A2 (en) 2008-06-05
WO2008066810A3 true WO2008066810A3 (en) 2009-01-15

Family

ID=39092899

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/US2007/024444 Ceased WO2008066810A2 (en) 2006-11-27 2007-11-27 Pleasant tasting dry powder compositions suitable for pulmonary delivery

Country Status (1)

Country Link
WO (1) WO2008066810A2 (en)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20150165037A1 (en) * 2012-07-05 2015-06-18 Arven llac Sanayi Ve Ticaret A.S. Inhalation compositions comprising corticosteroid and sorbitol
US10111957B2 (en) 2012-07-05 2018-10-30 Arven Ilac Snayi ve Ticaret A.S. Inhalation compositions comprising glucose anhydrous
WO2014007771A2 (en) 2012-07-05 2014-01-09 Sanovel Ilac Sanayi Ve Ticaret Anonim Sirketi Inhalation compositions comprising muscarinic receptor antagonist
KR20170003926A (en) * 2014-04-08 2017-01-10 산사 코포레이션 (바베이도스) 인코포레이티드 Nicotine formulations and methods of making the same
US20220257642A1 (en) * 2019-06-04 2022-08-18 Thirty Respiratory Limited Methods and compositions for generating nitric oxide and uses thereof to deliver nitric oxide via the respiratory tract

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
TEE, S. K. ET AL: "The use of different sugars as fine and coarse carriers for aerosolised salbutamol sulphate", INT. J. PHARM., vol. 208, 2000, pages 111 - 123, XP002470800 *

Also Published As

Publication number Publication date
WO2008066810A2 (en) 2008-06-05

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