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WO2008059339A3 - Isoquinoline derivatives as vanilloid receptor modulators - Google Patents

Isoquinoline derivatives as vanilloid receptor modulators Download PDF

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Publication number
WO2008059339A3
WO2008059339A3 PCT/IB2007/003457 IB2007003457W WO2008059339A3 WO 2008059339 A3 WO2008059339 A3 WO 2008059339A3 IB 2007003457 W IB2007003457 W IB 2007003457W WO 2008059339 A3 WO2008059339 A3 WO 2008059339A3
Authority
WO
WIPO (PCT)
Prior art keywords
isoquinoline derivatives
vanilloid receptor
receptor modulators
vanilloid
derivatives
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Ceased
Application number
PCT/IB2007/003457
Other languages
French (fr)
Other versions
WO2008059339A2 (en
Inventor
Laxmikant Atmaram Gharat
Ananta Dharma Shinde
Neelima Khairatkar-Joshi
Vidya G Kattige
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Ichnos Sciences SA
Original Assignee
Glenmark Pharmaceuticals SA
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Glenmark Pharmaceuticals SA filed Critical Glenmark Pharmaceuticals SA
Publication of WO2008059339A2 publication Critical patent/WO2008059339A2/en
Publication of WO2008059339A3 publication Critical patent/WO2008059339A3/en
Anticipated expiration legal-status Critical
Ceased legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D407/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having oxygen atoms as the only ring hetero atoms, not provided for by group C07D405/00
    • C07D407/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having oxygen atoms as the only ring hetero atoms, not provided for by group C07D405/00 containing two hetero rings
    • C07D407/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having oxygen atoms as the only ring hetero atoms, not provided for by group C07D405/00 containing two hetero rings linked by a chain containing hetero atoms as chain links
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D409/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
    • C07D409/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings
    • C07D409/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings linked by a chain containing hetero atoms as chain links

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

The present invention relates to substituted isoquinoline derivatives of formula I, which can be used as vanilloid receptor ligands, methods of treating diseases, condition and/or disorders modulated by vanilloid receptors with them, and processes for preparing them.
PCT/IB2007/003457 2006-11-13 2007-11-12 Isoquinoline derivatives as vanilloid receptor modulators Ceased WO2008059339A2 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
IN1884MU2006 2006-11-13
IN1884/MUM/2006 2006-11-13

Publications (2)

Publication Number Publication Date
WO2008059339A2 WO2008059339A2 (en) 2008-05-22
WO2008059339A3 true WO2008059339A3 (en) 2008-07-24

Family

ID=39310968

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/IB2007/003457 Ceased WO2008059339A2 (en) 2006-11-13 2007-11-12 Isoquinoline derivatives as vanilloid receptor modulators

Country Status (1)

Country Link
WO (1) WO2008059339A2 (en)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2010023512A1 (en) * 2008-08-28 2010-03-04 Matrix Laboratories Ltd. Novel vanilloid receptor modulators, process for their preparation and pharmaceutical compositions containing them
WO2010026128A1 (en) * 2008-09-02 2010-03-11 Glaxo Group Limited N-(3-methyl-5-isoquinolinyl)-n'-((3r)-1-[5-(trifluoromethyl)-2-pyridinyl]-3-pyrrolidinyl) urea for the treatment of rhinitis
TW201020236A (en) * 2008-10-17 2010-06-01 Abbott Lab TRPV1 antagonists
US8609692B2 (en) 2008-10-17 2013-12-17 Abbvie Inc. TRPV1 antagonists
TW201302681A (en) 2011-03-25 2013-01-16 Abbott Lab TRPV1 antagonists
WO2013096226A1 (en) 2011-12-19 2013-06-27 Abbvie Inc. Trpv1 antagonists
WO2013096223A1 (en) 2011-12-19 2013-06-27 Abbvie Inc. Trpv1 antagonists
US8796328B2 (en) 2012-06-20 2014-08-05 Abbvie Inc. TRPV1 antagonists
TW201711999A (en) 2015-09-03 2017-04-01 佛瑪治療公司 [6,6] fused bicyclic HDAC8 inhibitors
RU2755206C1 (en) 2020-05-20 2021-09-14 Федеральное государственное бюджетное учреждение науки Тихоокеанский институт биоорганической химии им. Г.Б. Елякова Дальневосточного отделения Российской академии наук (ТИБОХ ДВО РАН) Agent with prolonged analgesic action and medicinal product based thereon

Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2003080578A1 (en) * 2002-03-22 2003-10-02 Merck Sharp & Dohme Limited Heteroaromatic urea derivatives as vr-1 receptor modulators for treating pain
WO2006065484A2 (en) * 2004-11-24 2006-06-22 Abbott Laboratories Chromanylurea compounds that inhibit vanilloid receptor subtype 1 (vr1) receptor and uses thereof

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2003080578A1 (en) * 2002-03-22 2003-10-02 Merck Sharp & Dohme Limited Heteroaromatic urea derivatives as vr-1 receptor modulators for treating pain
WO2006065484A2 (en) * 2004-11-24 2006-06-22 Abbott Laboratories Chromanylurea compounds that inhibit vanilloid receptor subtype 1 (vr1) receptor and uses thereof

Also Published As

Publication number Publication date
WO2008059339A2 (en) 2008-05-22

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