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WO2008052037A3 - Matériaux d'emballage pour les formulations contenant des dérivés de 2-pyrrolidone - Google Patents

Matériaux d'emballage pour les formulations contenant des dérivés de 2-pyrrolidone Download PDF

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Publication number
WO2008052037A3
WO2008052037A3 PCT/US2007/082354 US2007082354W WO2008052037A3 WO 2008052037 A3 WO2008052037 A3 WO 2008052037A3 US 2007082354 W US2007082354 W US 2007082354W WO 2008052037 A3 WO2008052037 A3 WO 2008052037A3
Authority
WO
WIPO (PCT)
Prior art keywords
packaging materials
pyrrolidone derivatives
formulations containing
pyrrolidone
packaged products
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Ceased
Application number
PCT/US2007/082354
Other languages
English (en)
Other versions
WO2008052037A2 (fr
Inventor
Wesley Wehsin Han
Masood A Chowhan
Jang-Shing Chiou
L Wayne Schneider
Bhagwati P Kabra
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Alcon Research LLC
Original Assignee
Alcon Research LLC
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Alcon Research LLC filed Critical Alcon Research LLC
Publication of WO2008052037A2 publication Critical patent/WO2008052037A2/fr
Publication of WO2008052037A3 publication Critical patent/WO2008052037A3/fr
Anticipated expiration legal-status Critical
Ceased legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
    • A61K47/32—Macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. carbomers, poly(meth)acrylates, or polyvinyl pyrrolidone
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/16—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing nitrogen, e.g. nitro-, nitroso-, azo-compounds, nitriles, cyanates
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/16—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing nitrogen, e.g. nitro-, nitroso-, azo-compounds, nitriles, cyanates
    • A61K47/18—Amines; Amides; Ureas; Quaternary ammonium compounds; Amino acids; Oligopeptides having up to five amino acids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/26—Carbohydrates, e.g. sugar alcohols, amino sugars, nucleic acids, mono-, di- or oligo-saccharides; Derivatives thereof, e.g. polysorbates, sorbitan fatty acid esters or glycyrrhizin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0048—Eye, e.g. artificial tears

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Biochemistry (AREA)
  • Molecular Biology (AREA)
  • Inorganic Chemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Ophthalmology & Optometry (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

La présente invention concerne des matériaux d'emballage pratiquement exempts de propriétés d'adsorption et d'absorption des dérivés de la 2-pyrrolidone. Les produits sous emballage décrits ici assurent la rétention du dérivé de 2-pyrrolidone à l'intérieur de la formulation, ce qui maintient l'intégrité de telles formulations. Les produits sous emballage sont utiles pour les applications ophtalmiques, auriculaires et nasales. L'application ophtalmique inclut des utilisations thérapeutiques et des utilisations pour l'entretien des lentilles de contact.
PCT/US2007/082354 2006-10-24 2007-10-24 Matériaux d'emballage pour les formulations contenant des dérivés de 2-pyrrolidone Ceased WO2008052037A2 (fr)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US85432006P 2006-10-24 2006-10-24
US60/854,320 2006-10-24

Publications (2)

Publication Number Publication Date
WO2008052037A2 WO2008052037A2 (fr) 2008-05-02
WO2008052037A3 true WO2008052037A3 (fr) 2008-10-23

Family

ID=39203303

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/US2007/082354 Ceased WO2008052037A2 (fr) 2006-10-24 2007-10-24 Matériaux d'emballage pour les formulations contenant des dérivés de 2-pyrrolidone

Country Status (2)

Country Link
US (1) US20080093247A1 (fr)
WO (1) WO2008052037A2 (fr)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20080095863A1 (en) * 2006-10-24 2008-04-24 Alcon Manufacturing Ltd. 2-pyrrolidone derivatives for preservation of ophthalmic, otic and nasal compositions
TWI544927B (zh) * 2008-03-17 2016-08-11 愛爾康研究有限公司 具有低濃度的表面活性劑以促進治療劑之生物可利用性的藥學組成物
PT2254549E (pt) * 2008-03-17 2014-01-30 Alcon Res Ltd Composições farmacêuticas aquosas que contêm complexos de borato-poliol
TWI489997B (zh) * 2009-06-19 2015-07-01 Alcon Res Ltd 含有硼酸－多元醇錯合物之水性藥學組成物
SG11201608402WA (en) * 2014-05-07 2016-11-29 Croma Pharma Ges M B H Aqueous ophthalmic solution and method for treating dry eye syndrome
US11253625B2 (en) * 2018-06-27 2022-02-22 Bausch & Lomb Incorporated Ophthalmic device packaging solutions comprising a poloxamine/erythritol mixture

Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1991007192A1 (fr) * 1989-11-21 1991-05-30 Schering Corporation Systeme de desinfection de lentilles de contact
WO2004019837A1 (fr) * 2002-08-29 2004-03-11 Pharmacia & Upjohn Company Llc Emballage de produit medicinal
WO2008052031A2 (fr) * 2006-10-24 2008-05-02 Alcon Research, Ltd. Dérivés de 2-pyrrolidone pour la conservation des compositions ophtalmiques, auriculaires et nasales

Family Cites Families (17)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4883658A (en) * 1986-04-28 1989-11-28 Holly Frank J Ophthalmic solution for treatment of dry-eye syndrome
US5294644A (en) * 1986-06-27 1994-03-15 Isp Investments Inc. Surface active lactams
US4804539A (en) * 1986-07-28 1989-02-14 Liposome Technology, Inc. Ophthalmic liposomes
US4914088A (en) * 1987-04-02 1990-04-03 Thomas Glonek Dry eye treatment solution and method
US5278151A (en) * 1987-04-02 1994-01-11 Ocular Research Of Boston, Inc. Dry eye treatment solution
US5075104A (en) * 1989-03-31 1991-12-24 Alcon Laboratories, Inc. Ophthalmic carboxy vinyl polymer gel for dry eye syndrome
ZA912797B (en) * 1990-05-29 1992-12-30 Boston Ocular Res Dry eye treatment process and solution
EP0459148B1 (fr) * 1990-05-29 1996-01-03 Ocular Research Of Boston Inc. Composition pour le traitement des maladies de type dry eye
JP3256997B2 (ja) * 1990-08-30 2002-02-18 千寿製薬株式会社 安定な水性製剤
ZA927277B (en) * 1991-10-02 1993-05-19 Boston Ocular Res Dry eye treatment process and solution.
WO1996003158A1 (fr) * 1994-07-22 1996-02-08 Alcon Laboratories, Inc. Utilisation d'acides amines de faible poids moleculaire dans des compositions ophtalmiques
US6964796B1 (en) * 1996-10-18 2005-11-15 Toyo Seikan Kaisha, Ltd. Oxygen-absorbing resin composition and packaging container, packaging material, cap or liner material having oxygen absorbability
AU2001256714A1 (en) * 2000-05-15 2001-11-26 Kissei Pharmaceutical Co. Ltd. Water-based liquid preparation
US6916842B2 (en) * 2003-03-24 2005-07-12 E. I. Du Pont De Nemours And Company Production of 5-methyl-n-(methyl aryl)-2-pyrrolidone, 5-methyl-n-(methyl cycloalkyl)-2-pyrrolidone and 5-methyl-n-alkyl-2-pyrrolidone by reductive amination of levulinic acid esters with cyano compounds
US6818593B2 (en) * 2003-03-24 2004-11-16 E. I. Du Pont De Nemours And Company Production of 5-Methyl-N-aryl-2-pyrrolidone and 5-methyl-N-alkyl-2-pyrrolidone by reductive amination of levulinic acid with nitro compounds
US20040192938A1 (en) * 2003-03-24 2004-09-30 Manzer Leo Ernest Production of 5-mehyl-N-aryl-2-pyrrolidone and 5-methyl-N-alkyl-2-pyrrolidone by reductive of levulinic acid esters with aryl and alkyl amines
US7030249B2 (en) * 2003-09-10 2006-04-18 E. I. Upont De Nemours And Company Process for converting α-angelica lactone to 5-methyl-N-alkyl-2-pyrrolidone using alkyl amines

Patent Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1991007192A1 (fr) * 1989-11-21 1991-05-30 Schering Corporation Systeme de desinfection de lentilles de contact
WO2004019837A1 (fr) * 2002-08-29 2004-03-11 Pharmacia & Upjohn Company Llc Emballage de produit medicinal
WO2008052031A2 (fr) * 2006-10-24 2008-05-02 Alcon Research, Ltd. Dérivés de 2-pyrrolidone pour la conservation des compositions ophtalmiques, auriculaires et nasales

Also Published As

Publication number Publication date
US20080093247A1 (en) 2008-04-24
WO2008052037A2 (fr) 2008-05-02

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