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WO2008040520A1 - Procédé pour l'emballage automatique de médicaments - Google Patents

Procédé pour l'emballage automatique de médicaments Download PDF

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Publication number
WO2008040520A1
WO2008040520A1 PCT/EP2007/008532 EP2007008532W WO2008040520A1 WO 2008040520 A1 WO2008040520 A1 WO 2008040520A1 EP 2007008532 W EP2007008532 W EP 2007008532W WO 2008040520 A1 WO2008040520 A1 WO 2008040520A1
Authority
WO
WIPO (PCT)
Prior art keywords
packaging
storage
drug
computer
packaging machine
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Ceased
Application number
PCT/EP2007/008532
Other languages
German (de)
English (en)
Inventor
Manfred Vogt
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Individual
Original Assignee
Individual
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Individual filed Critical Individual
Publication of WO2008040520A1 publication Critical patent/WO2008040520A1/fr
Anticipated expiration legal-status Critical
Ceased legal-status Critical Current

Links

Classifications

    • BPERFORMING OPERATIONS; TRANSPORTING
    • B65CONVEYING; PACKING; STORING; HANDLING THIN OR FILAMENTARY MATERIAL
    • B65GTRANSPORT OR STORAGE DEVICES, e.g. CONVEYORS FOR LOADING OR TIPPING, SHOP CONVEYOR SYSTEMS OR PNEUMATIC TUBE CONVEYORS
    • B65G1/00Storing articles, individually or in orderly arrangement, in warehouses or magazines
    • B65G1/02Storage devices
    • B65G1/04Storage devices mechanical
    • B65G1/137Storage devices mechanical with arrangements or automatic control means for selecting which articles are to be removed
    • B65G1/1373Storage devices mechanical with arrangements or automatic control means for selecting which articles are to be removed for fulfilling orders in warehouses
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B65CONVEYING; PACKING; STORING; HANDLING THIN OR FILAMENTARY MATERIAL
    • B65BMACHINES, APPARATUS OR DEVICES FOR, OR METHODS OF, PACKAGING ARTICLES OR MATERIALS; UNPACKING
    • B65B57/00Automatic control, checking, warning, or safety devices
    • B65B57/10Automatic control, checking, warning, or safety devices responsive to absence, presence, abnormal feed, or misplacement of articles or materials to be packaged
    • B65B57/14Automatic control, checking, warning, or safety devices responsive to absence, presence, abnormal feed, or misplacement of articles or materials to be packaged and operating to control, or stop, the feed of articles or material to be packaged
    • GPHYSICS
    • G07CHECKING-DEVICES
    • G07FCOIN-FREED OR LIKE APPARATUS
    • G07F11/00Coin-freed apparatus for dispensing, or the like, discrete articles
    • G07F11/02Coin-freed apparatus for dispensing, or the like, discrete articles from non-movable magazines
    • G07F11/38Coin-freed apparatus for dispensing, or the like, discrete articles from non-movable magazines in which the magazines are horizontal
    • G07F11/42Coin-freed apparatus for dispensing, or the like, discrete articles from non-movable magazines in which the magazines are horizontal the articles being delivered by motor-driven means
    • GPHYSICS
    • G07CHECKING-DEVICES
    • G07FCOIN-FREED OR LIKE APPARATUS
    • G07F11/00Coin-freed apparatus for dispensing, or the like, discrete articles
    • G07F11/02Coin-freed apparatus for dispensing, or the like, discrete articles from non-movable magazines
    • G07F11/44Coin-freed apparatus for dispensing, or the like, discrete articles from non-movable magazines in which magazines the articles are stored in bulk
    • GPHYSICS
    • G07CHECKING-DEVICES
    • G07FCOIN-FREED OR LIKE APPARATUS
    • G07F17/00Coin-freed apparatus for hiring articles; Coin-freed facilities or services
    • G07F17/0092Coin-freed apparatus for hiring articles; Coin-freed facilities or services for assembling and dispensing of pharmaceutical articles
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B65CONVEYING; PACKING; STORING; HANDLING THIN OR FILAMENTARY MATERIAL
    • B65GTRANSPORT OR STORAGE DEVICES, e.g. CONVEYORS FOR LOADING OR TIPPING, SHOP CONVEYOR SYSTEMS OR PNEUMATIC TUBE CONVEYORS
    • B65G2201/00Indexing codes relating to handling devices, e.g. conveyors, characterised by the type of product or load being conveyed or handled
    • B65G2201/02Articles
    • B65G2201/027Tablets, capsules, pills or the like

Definitions

  • the invention relates to a method for the automatic packaging of medicaments, wherein by means of a computer-controlled packaging machine, medicaments are taken according to a compilation specification from several simultaneously connected to the packaging machine drug containers containing each drug of a single variety, combined to packaged goods lo and enclosed with a packaging
  • the invention relates to a packaging system for carrying out the method.
  • US 2004/0182044 A1 discloses packaging machines which are used to automatically assemble and pack medicaments which are in the form of tablets, capsules or i5 powders in accordance with an assembly specification.
  • Such machines are z. B. used in hospitals to put together for each individual patient, the drug to be taken by this in each case. The compilation takes place in accordance with the prescription of the patient treating the patient
  • the known packaging machines produce a package for each patient.
  • the drug to be taken by the patient of a packaging usually wrapped in the form of a welded film.
  • On the slide is also an imprint with the
  • the known packaging machines are designed to be connected simultaneously with a correspondingly large number of drug containers. Each drug container is intended for a single-variety medicine.
  • Packaging machines are known which are designed for more than 500 drug containers.
  • the drugs eg. As individual tablets, ejected from the corresponding drug containers. The ejected tablets then fall into a funnel, from where they enter a filling unit, by means of which the tablets are filled into foil sachets.
  • Due to the large number of drug containers conventional packaging machines are inevitably designed so that the drug ejected from the drug containers must travel very long distances through the machine until they pass through the filling unit in the foil sachets.
  • the drugs are conveyed in the conventional packaging machines by gravity from the drug containers to the filling unit.
  • the pharmaceuticals have to cover large drop heights, since the drug containers are arranged in a space-saving manner in the automatic packaging machine on several levels one above the other.
  • the conventional packaging machines disadvantageously result in a high degree of abrasion of the processed medicaments. This abrasion causes significant contamination of the machine, so it must be cleaned daily to ensure proper operation. It is also common to observe that tablets break during the packaging process.
  • a further disadvantage is that the known packaging machines, again due to the large number of drug containers, constructed very expensive and thus are expensive to manufacture and maintain.
  • This object is achieved by the invention starting from a method of the type mentioned above in that the drug containers previously, i. before the actual blistering process, removed by means of a computer-controlled handling device of an automatic storage system in accordance with the compilation specification from a storage warehouse and connected to the packaging machine.
  • the core idea of the invention is to combine a packaging machine with an automatic storage system.
  • the computer-controlled handling device of the automatic storage system supplies the packaging machine with the drug containers with those drugs that are required according to the respective compilation specification.
  • the drug containers are stored in the stock store of the automatic storage system.
  • the stock can be easily sized large enough to accommodate a correspondingly large number of drug containers. The number of processed
  • Pharmaceuticals are not limited by their individual construction and design, as in conventional packaging machines. Rather, according to the invention, the number of drug containers is determined only by the size of the stock. Another advantage of the method according to the invention is that the packaging machine can be designed for simultaneous connection with comparatively few drug containers. At the same time, only so many drug containers must be connected to the automatic packaging machine, as different drugs must be combined and packaged simultaneously according to an individual compilation specification. Most rarely, a regulation includes
  • Medication of a patient more than 10 or 20 different medicines is sufficient if the packaging machine for simultaneous connection with up to 10 or 20 drug containers is designed. Due to the small number of drug containers, the distances to be traveled by the drugs during the packaging process are significantly shorter within the machine than in the previously known machines. Accordingly, abrasion and soiling by the processed drugs are significantly reduced. In addition, unwanted breakage of tablets during automatic packaging by the method according to the invention can be completely avoided.
  • a useful embodiment of the method according to the invention provides that, according to the compilation specification, unnecessary drug lo containers are separated from the automatic packaging machine by means of the handling device of the storage system and deposited at an intermediate storage location or at a storage location of the storage bin.
  • the computer control which is used in the method according to the invention recognizes which of the drug containers which are connected to the packaging machine are not required in accordance with the composition specification of the packaging order to be processed next.
  • these unnecessary drug containers are separated from the packaging machine and then either deposited at an intermediate storage or at a storage location of the storage
  • the storage at an intermediate storage point is useful to ensure short distances of the handling device and thereby save time, especially the drug container of frequently requested drugs can be stored with advantage at the intermediate storage.
  • a useful further development of the method according to the invention provides that the drug containers have a machine-readable identification, the drug containers being recognized on the basis of their identification by means of a corresponding reading device of the automatic packaging machine.
  • the labeling of the drug container indicates which drug is in it.
  • the reading device of the automatic packaging machine can be determined whether each of the correct drug container was supplied to the packaging machine of the automatic storage system.
  • Come as a machine-readable label usual barcodes or transponders, for example in the form of known RFI D-Tags in question.
  • a conventional and commercially available storage system which is used for storage of medicaments in pharmacies, can be used in combination with a packaging machine for assembling and packaging of individual medicaments by the inventive method.
  • the inventive method is carried out so that in addition to the drug containers packaged drugs are stored by means of the storage system, the drugs are identified during storage process by means of an identification device and then stored by means of the computer-controlled handling device to a storage location of the storage store, and wherein the drug
  • the storage system used in the method according to the invention thus fulfills a dual function. Namely, the drug container which is to be connected to the automatic packaging machine is stored in the storage warehouse of the storage system. On the other hand, individual medicament packs are stored in the storage warehouse, which can be individually stored and retrieved by means of the computer-controlled handling device 5, preferably according to the system of free storage space allocation in order to optimally utilize the storage space available in the storage warehouse. If a user of the storage system requests a drug of a certain variety, the computer of the storage system determines the storage location of the lo drug desired and controls the handling device, so that this removes the outsourced drug package from the storage and transported out of the storage system.
  • the computer of the storage system After the removal of the drug, the computer of the storage system automatically logs the paging operation. At the same time, the released i5 storage location for subsequent drugs to be stored in the memory of the computer is noted as free.
  • the medicines are stored in the warehouse only after the space available in each case in the camp. Further classification criteria, for example according to the type of medicinal product, are not taken into account. Compared to conventional, hand-guided
  • the drug containers are weighed before and / or after a packaging operation in order to check, based on the weight of the 5 drug containers, whether the medicaments have been compiled correctly in accordance with the compilation specification.
  • a weighing device connected to the computer is expediently provided for determining the weight of the drug container. It is readily possible to deposit in the computer that is used to control the o automatic packaging and also to control the automatic storage system, the weight of each contained in the drug containers individual medicines. By comparing the weight of each drug container before and after a packaging operation, it can be determined whether the drugs are correspondingly taken from the drug container and packed in the correct number. If it is determined by the weight that the packaging process has not been carried out correctly, a corresponding warning signal is generated, the produced package discarded and the packaging process repeated.
  • the object underlying the invention is also achieved by a packaging system for the automatic packaging of drugs, with a computer that is connected to a computer-controlled packaging machine, the drug according to a compilation specification of several simultaneously connected to the packaging machine drug containers, each drug of a single variety contains, removes, packaged to Packgut and encloses with a packaging.
  • the packaging system comprises a likewise controlled by the computer handling device of an automatic storage system, which removes the drug container prior to a packaging operation in accordance with the compilation specification from a storage and connects to the packaging machine.
  • the drawing shows schematically an inventive packaging system in plan view.
  • the system shown in the drawing consists on the one hand of a storage system comprising two opposite rows of shelves with shelf modules 1. These shelf modules form the storage of the storage system. On the shelves individual drug packages 2 are stored.
  • the storage system comprises a storage module 3 and an identification device 4. Between the rows of shelves, a handling device 5 is arranged, which is movable in the direction of the double arrow 6 and handles the drug packages 2 during the storage and retrieval process.
  • the storage system is connected to a computer 7, which controls the identification device 4 and the handling device 5.
  • a data network 8 via which it receives its inputs.
  • Part of the system shown in the drawing is also a packaging machine 9, which is also controlled by the computer 7.
  • the computer 7 is sent a compilation specification in the form of a regulation.
  • the automatic packaging machine 9 takes from several drug containers 10, which are connected simultaneously to the automatic packaging machine 9 and which each contain drugs of a single variety, the corresponding drugs, eg. B. in the form of individual tablets.
  • the packaging machine combines these medicines into packaged goods and encloses them with a packaging material.
  • the packaging used is a film tube, which is located on a supply roll 11.
  • the film tube is printed by means of a printing device 12.
  • the film tube contains an imprint with the name of the patient for whom the processed prescription is intended, including the date of birth and, if applicable, further information regarding the ward and room number in a hospital.
  • the names of the compiled medicines are printed, indicating the prescribed intake times.
  • the drugs are filled into the film tube.
  • the printed and filled film tube by means of a
  • Welding unit welded. At the end of a package 14 is issued. This consists of a welded on two sides piece of film tube with therein tablets 15 and an imprint 16th
  • the packaging system shown in the drawing functions as follows:
  • the packaged drug 2 or the drug container 10 are inserted by hand into the storage module 3. From this storage module 3, the handling device 5 removes the drug packages or the drug containers individually and transports them to the identification device 4.
  • the identification device 4 identifies each
  • the identification device 4 reads the PZN (pharmaceutical central number) printed as a barcode.
  • the identification device 4 reads the printed barcode to determine the drug type.
  • the computer 7 controls the handling device 5 in such a way that, after the identification, it picks up the medicament pack or the medicament container from the identification device 4 and deposits it at a free storage location of the shelf storage 1. By means of the computer 7, the relevant storage location is stored.
  • an operator requests a particular type of drug through interactive input to the computer 7. Then the computer 7 selects a corresponding drug package of this type and controls the handling device 5 such that it removes the selected drug 2 from the shelf 1 and transports it to the module 3.
  • the computer 7 controls the handling device 5 in such a way that it removes the corresponding drug containers 10 individually from the shelf 1, transported to the packaging machine 9 and with this combines. As soon as all the drug containers 10 required for the regulation are connected to the packaging machine 9, the automatic packaging machine 9 starts
  • the computer 7 checks which of the pharmaceutical containers 10 connected to the automatic packaging machine 9 have to be exchanged and performs this accordingly by means of the handling device 5. Unnecessary 5 drug containers 10 are separated from the packaging machine 9 and stored at a free storage location of the shelf 1. A region 17 of the shelf 1, which is located in the immediate vicinity of the packaging machine 9, serves as an intermediate storage point, where drug containers 10 can be stored.
  • drug containers 10 are removed from the storage bin by means of the computer-controlled handling device 5 in accordance with a subsequent prescription already present on the computer 7 and deposited at the intermediate storage point 17, from where they are taken up by the handling device 5 after completion of the current packaging operation within a short time with the Packaging machines 9 are connected for the next packaging operation.
  • the drug containers 10 can be weighed before and / or after a packaging operation in order to check, based on the weight, whether the medicaments 5 have been correctly assembled in accordance with the respective composition specification.
  • the system comprises a weighing device 18 connected to the computer 7. The system automatically detects when one of the drug containers 10 is empty.
  • this drug container 10 is removed by means of the handling device 5 from the lo shelf 1 and transported to the module 3. From there, the drug container 10 can be taken over by an operator and refilled.
  • the z. B. hygroscopic or in unpackaged form are not or may not come in contact with other drugs due to risk of contamination i5 may be provided that each of the drug container 10 each contain individually packaged drugs, eg. B. in the form of piecemeal blistered tablets. These are then packaged together with medicines into packages 14. The medicinal products concerned are then bleached twice.
  • the automatic packaging machine 9 also allows a partial manual

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  • Physics & Mathematics (AREA)
  • General Physics & Mathematics (AREA)
  • Engineering & Computer Science (AREA)
  • Mechanical Engineering (AREA)
  • Basic Packing Technique (AREA)
  • Medical Preparation Storing Or Oral Administration Devices (AREA)

Abstract

L'invention concerne un procédé pour l'emballage automatique de médicaments. À l'aide d'une machine automatique d'emballage (9) commandée par ordinateur, des médicaments sont sortis de plusieurs conteneurs de médicaments (10) reliés simultanément à la machine automatique d'emballage (9) selon une spécification d'assemblage, chaque conteneur contenant des médicaments d'une seule sorte, sont réunis pour former un produit emballé (15) et sont entourés par un moyen d'emballage. L'objet de l'invention est un procédé amélioré pour l'emballage automatique de médicaments. Ce procédé doit fonctionner avec une machine automatique d'emballage de conception plus simple, laquelle est moins sensible aux salissures dues aux médicaments élaborés. À cet effet, les conteneurs de médicaments (10) sont préalablement sortis d'une réserve de stockage (1) à l'aide d'un dispositif de maniement commandé par ordinateur (5) d'un système de stockage automatique, selon les spécifications d'assemblage, puis ils sont mis en liaison avec la machine automatique d'emballage (9). L'invention concerne en outre un système d'emballage pour la mise en oevre du procédé.
PCT/EP2007/008532 2006-09-29 2007-10-01 Procédé pour l'emballage automatique de médicaments Ceased WO2008040520A1 (fr)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DE202006015150.8 2006-09-29
DE200620015150 DE202006015150U1 (de) 2006-09-29 2006-09-29 System zur automatischen Verpackung von Arzneimitteln

Publications (1)

Publication Number Publication Date
WO2008040520A1 true WO2008040520A1 (fr) 2008-04-10

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Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/EP2007/008532 Ceased WO2008040520A1 (fr) 2006-09-29 2007-10-01 Procédé pour l'emballage automatique de médicaments

Country Status (2)

Country Link
DE (1) DE202006015150U1 (fr)
WO (1) WO2008040520A1 (fr)

Cited By (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US9150119B2 (en) 2013-03-15 2015-10-06 Aesynt Incorporated Apparatuses, systems, and methods for anticipating and delivering medications from a central pharmacy to a patient using a track based transport system
CN105217199A (zh) * 2014-06-05 2016-01-06 海尔集团技术研发中心 酒瓶存取机构、自动存取酒柜和酒瓶存取方法
US9511945B2 (en) 2012-10-12 2016-12-06 Aesynt Incorporated Apparatuses, systems, and methods for transporting medications from a central pharmacy to a patient in a healthcare facility

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DE102010033170A1 (de) 2010-08-03 2012-02-09 Krones Aktiengesellschaft Verfahren und Vorrichtung zum Betreiben einer Anlage zum Behandeln von Behältnissen mit gesteuerter Parameteranwahl
CN104309867A (zh) * 2014-08-29 2015-01-28 成都锦汇科技有限公司 一种多列条状包装机的进料方法

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DE60106989T2 (de) * 2000-02-01 2005-12-01 Johnson & Johnson Vision Care, Inc., Jacksonville Vorrichtung und Verfahren für automatisiertes Warenlager
EP1440920A2 (fr) * 2003-01-07 2004-07-28 Westfalia WST Systemtechnik GmbH & Co. KG Méthode et dispositif pour l'empaquetage d'articles unitaires
US20040182044A1 (en) * 2003-03-19 2004-09-23 Kim Jun Ho Automatic tablet dispensing and packaging system
DE102005007730A1 (de) * 2005-02-19 2006-08-31 Dirk Rolf Beils Verfahren und Lagersystem für die rechnergestützte Lagerung von Arzneimitteln
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Cited By (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US9511945B2 (en) 2012-10-12 2016-12-06 Aesynt Incorporated Apparatuses, systems, and methods for transporting medications from a central pharmacy to a patient in a healthcare facility
US10029856B2 (en) 2012-10-12 2018-07-24 Aesynt Incorporated Apparatuses, systems, and methods for transporting medications from a central pharmacy to a patient in a healthcare facility
US10315851B2 (en) 2012-10-12 2019-06-11 Aesynt Incorporated Apparatuses, systems, and methods for transporting medications from a central pharmacy to a patient in a healthcare facility
US10518981B2 (en) 2012-10-12 2019-12-31 Aesynt Incorporated Apparatuses, systems, and methods for transporting medications from a central pharmacy to a patient in a healthcare facility
US10850926B2 (en) 2012-10-12 2020-12-01 Omnicell, Inc. Apparatuses, systems, and methods for transporting medications from a central pharmacy to a patient in a healthcare facility
US11694782B2 (en) 2012-10-12 2023-07-04 Omnicell, Inc. Apparatuses, systems, and methods for transporting medications from a central pharmacy to a patient in a healthcare facility
US9150119B2 (en) 2013-03-15 2015-10-06 Aesynt Incorporated Apparatuses, systems, and methods for anticipating and delivering medications from a central pharmacy to a patient using a track based transport system
CN105217199A (zh) * 2014-06-05 2016-01-06 海尔集团技术研发中心 酒瓶存取机构、自动存取酒柜和酒瓶存取方法

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