WO2007103511B1 - Multi-layer medical patch with impermeable center - Google Patents
Multi-layer medical patch with impermeable centerInfo
- Publication number
- WO2007103511B1 WO2007103511B1 PCT/US2007/005947 US2007005947W WO2007103511B1 WO 2007103511 B1 WO2007103511 B1 WO 2007103511B1 US 2007005947 W US2007005947 W US 2007005947W WO 2007103511 B1 WO2007103511 B1 WO 2007103511B1
- Authority
- WO
- WIPO (PCT)
- Prior art keywords
- group
- spots
- sheet
- spot
- heads
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Ceased
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0053—Mouth and digestive tract, i.e. intraoral and peroral administration
- A61K9/006—Oral mucosa, e.g. mucoadhesive forms, sublingual droplets; Buccal patches or films; Buccal sprays
Landscapes
- Health & Medical Sciences (AREA)
- Nutrition Science (AREA)
- Physiology (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Medicinal Preparation (AREA)
- Ink Jet (AREA)
Abstract
A muco-adhesive patch for delivery of drugs into mucous membranes. On the muco-contact side, a water impermeable layer covers the center of the patch and less than half of the muco-contact side of the patch. Drugs may be added by mixing the drug with an adhesive material and placing a spot of the drug plus adhesive onto the exposed side of the water impermeable layer. A lenticular medical patch with a thin, tapered edge can be made with multiple layers by passing a single sheet such as a sheet of plastic through a production line in which each layer is applied in turn maintaining registration by reference to edges of the sheet or to marks on the sheet.
Claims
AMENDED CLAIMS [Received by the International Bureau on 02 October 2007 (02.10.2007)]
b. then placing molecules of a substantially water impermeable layer on top of each drug spot and entirely covering each drug spot.
5 15. The method of claim 14 wherein the substantially water impermeable layer is sprayed onto the sheet.
16. The method of claim 14 wherein the substantially water impermeable layer is printed onto the sheet.
10
17. A method of making a medical patch comprising a plurality of layers, the method comprising: a. having a machine with a group of material placement heads configured to place a group of spots of patch material onto a sheet of registration material,
15 one spot for each head in the group of heads; b. as a sheet of registration material moves past the heads, using the heads to place a first group of spots of patch material onto the sheet; and c. as the sheet of registration material moves past placement heads a second time, placing a second group of spots of patch material onto the sheet,
20 each spot in the second group of spots being placed on top of a spot in the first group of spots.
18. The method of claim 17 where the heads that place the first group of spots also place the second group of spots.
25
19. The method of claims 17 where the heads that place the second group of spots are different from the heads that place the first group of spots.
20. The method of claim 19 where the spots in the first group are placed by 30 printing and the spots in the second group are placed by depositing.
21. The method of claim 19 where the spots in the first group are placed by depositing and the spots in the second group are placed by spraying.
35 22. The method of claim 17 where each spot in the second group of spots entirely covers a spot in the first group of spots.
23. The method of claim 17 where each spot in the second group of spots leaves uncovered a perimeter of a spot in the first group of spots.
Priority Applications (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP2008558399A JP2009528900A (en) | 2006-03-07 | 2007-03-07 | Medical multilayer patch with impermeable center |
| EP07752632A EP2023908A1 (en) | 2006-03-07 | 2007-03-07 | Multi-layer medical patch with impermeable center |
| US12/231,841 US8349120B2 (en) | 2006-03-07 | 2008-09-05 | Multi-layer patch made on a sheet and enclosed in a blister |
Applications Claiming Priority (4)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US78000906P | 2006-03-07 | 2006-03-07 | |
| US60/780,009 | 2006-03-07 | ||
| US79563706P | 2006-04-26 | 2006-04-26 | |
| US60/795,637 | 2006-04-26 |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| US12/231,841 Continuation US8349120B2 (en) | 2006-03-07 | 2008-09-05 | Multi-layer patch made on a sheet and enclosed in a blister |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| WO2007103511A1 WO2007103511A1 (en) | 2007-09-13 |
| WO2007103511B1 true WO2007103511B1 (en) | 2008-02-28 |
Family
ID=38475193
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| PCT/US2007/005947 Ceased WO2007103511A1 (en) | 2006-03-07 | 2007-03-07 | Multi-layer medical patch with impermeable center |
Country Status (3)
| Country | Link |
|---|---|
| EP (1) | EP2023908A1 (en) |
| JP (1) | JP2009528900A (en) |
| WO (1) | WO2007103511A1 (en) |
Families Citing this family (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| KR101264843B1 (en) * | 2008-12-31 | 2013-05-16 | 주식회사 삼양바이오팜 | Method of Producing a Patch for Transdermal Administration of Volatile or Heat-Sensitive Drug, and the Patch Thereof |
| JP5806701B2 (en) * | 2013-05-07 | 2015-11-10 | 日本写真印刷株式会社 | Method for producing transdermal patch and transdermal patch |
Family Cites Families (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP2950613B2 (en) * | 1989-11-03 | 1999-09-20 | ライカー ラボラトリーズ，インコーポレイティド | Bioadhesive composition and plaster |
| CA2345808A1 (en) * | 1998-10-02 | 2000-04-13 | 3M Innovative Properties Company | Mucosal originated drug delivery systems and animal applications |
| KR100302572B1 (en) * | 1998-11-10 | 2002-03-21 | 허계성 | Film-type oral mucoadhesive agent and its manufacturing method |
| KR20030054221A (en) * | 2001-12-24 | 2003-07-02 | 애경산업(주) | Composite film composition for oral cavity and preparing method thereof |
| JP5137286B2 (en) * | 2003-06-10 | 2013-02-06 | 帝國製薬株式会社 | Fentanyl-containing oral mucosal patch |
-
2007
- 2007-03-07 EP EP07752632A patent/EP2023908A1/en not_active Withdrawn
- 2007-03-07 JP JP2008558399A patent/JP2009528900A/en not_active Withdrawn
- 2007-03-07 WO PCT/US2007/005947 patent/WO2007103511A1/en not_active Ceased
Also Published As
| Publication number | Publication date |
|---|---|
| WO2007103511A1 (en) | 2007-09-13 |
| EP2023908A1 (en) | 2009-02-18 |
| JP2009528900A (en) | 2009-08-13 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| 121 | Ep: the epo has been informed by wipo that ep was designated in this application | ||
| WWE | Wipo information: entry into national phase |
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| WWE | Wipo information: entry into national phase |
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