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WO2007147445A3 - Keratinbindende effektormoleküle und verfahren zu deren herstellung - Google Patents

Keratinbindende effektormoleküle und verfahren zu deren herstellung Download PDF

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Publication number
WO2007147445A3
WO2007147445A3 PCT/EP2006/068470 EP2006068470W WO2007147445A3 WO 2007147445 A3 WO2007147445 A3 WO 2007147445A3 EP 2006068470 W EP2006068470 W EP 2006068470W WO 2007147445 A3 WO2007147445 A3 WO 2007147445A3
Authority
WO
WIPO (PCT)
Prior art keywords
keratin
effector molecules
binding effector
production
hair
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Ceased
Application number
PCT/EP2006/068470
Other languages
English (en)
French (fr)
Other versions
WO2007147445A2 (de
Inventor
Heiko Barg
Burghard Liebmann
Martin Voelkert
Arne Ptock
Heike Reents
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
BASF SE
Original Assignee
BASF SE
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by BASF SE filed Critical BASF SE
Priority to US12/094,833 priority Critical patent/US20090098076A1/en
Priority to MX2008006524A priority patent/MX2008006524A/es
Priority to BRPI0618980A priority patent/BRPI0618980A2/pt
Priority to CA002630903A priority patent/CA2630903A1/en
Priority to EP06851524A priority patent/EP1957111A2/de
Priority to AU2006344932A priority patent/AU2006344932A1/en
Priority to JP2008541699A priority patent/JP2009517361A/ja
Publication of WO2007147445A2 publication Critical patent/WO2007147445A2/de
Publication of WO2007147445A3 publication Critical patent/WO2007147445A3/de
Anticipated expiration legal-status Critical
Ceased legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D207/00—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D207/02—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D207/44—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having three double bonds between ring members or between ring members and non-ring members
    • C07D207/444—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having three double bonds between ring members or between ring members and non-ring members having two doubly-bound oxygen atoms directly attached in positions 2 and 5
    • C07D207/448—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having three double bonds between ring members or between ring members and non-ring members having two doubly-bound oxygen atoms directly attached in positions 2 and 5 with only hydrogen atoms or radicals containing only hydrogen and carbon atoms directly attached to other ring carbon atoms, e.g. maleimide
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/50—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
    • A61K47/51—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent
    • A61K47/62—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being a protein, peptide or polyamino acid
    • A61K47/64—Drug-peptide, drug-protein or drug-polyamino acid conjugates, i.e. the modifying agent being a peptide, protein or polyamino acid which is covalently bonded or complexed to a therapeutically active agent
    • A61K47/6435—Drug-peptide, drug-protein or drug-polyamino acid conjugates, i.e. the modifying agent being a peptide, protein or polyamino acid which is covalently bonded or complexed to a therapeutically active agent the peptide or protein in the drug conjugate being a connective tissue peptide, e.g. collagen, fibronectin or gelatin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/64—Proteins; Peptides; Derivatives or degradation products thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q19/00—Preparations for care of the skin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q3/00—Manicure or pedicure preparations
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q5/00—Preparations for care of the hair
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D207/00—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D207/02—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D207/44—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having three double bonds between ring members or between ring members and non-ring members
    • C07D207/444—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having three double bonds between ring members or between ring members and non-ring members having two doubly-bound oxygen atoms directly attached in positions 2 and 5
    • C07D207/448—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having three double bonds between ring members or between ring members and non-ring members having two doubly-bound oxygen atoms directly attached in positions 2 and 5 with only hydrogen atoms or radicals containing only hydrogen and carbon atoms directly attached to other ring carbon atoms, e.g. maleimide
    • C07D207/452—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having three double bonds between ring members or between ring members and non-ring members having two doubly-bound oxygen atoms directly attached in positions 2 and 5 with only hydrogen atoms or radicals containing only hydrogen and carbon atoms directly attached to other ring carbon atoms, e.g. maleimide with hydrocarbon radicals, substituted by hetero atoms, directly attached to the ring nitrogen atom
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2800/00—Properties of cosmetic compositions or active ingredients thereof or formulation aids used therein and process related aspects
    • A61K2800/40—Chemical, physico-chemical or functional or structural properties of particular ingredients
    • A61K2800/57—Compounds covalently linked to a(n inert) carrier molecule, e.g. conjugates, pro-fragrances
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2800/00—Properties of cosmetic compositions or active ingredients thereof or formulation aids used therein and process related aspects
    • A61K2800/80—Process related aspects concerning the preparation of the cosmetic composition or the storage or application thereof
    • A61K2800/94—Involves covalent bonding to the substrate
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q1/00—Make-up preparations; Body powders; Preparations for removing make-up
    • A61Q1/02—Preparations containing skin colorants, e.g. pigments
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q17/00—Barrier preparations; Preparations brought into direct contact with the skin for affording protection against external influences, e.g. sunlight, X-rays or other harmful rays, corrosive materials, bacteria or insect stings
    • A61Q17/04—Topical preparations for affording protection against sunlight or other radiation; Topical sun tanning preparations
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q19/00—Preparations for care of the skin
    • A61Q19/002—Aftershave preparations
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q19/00—Preparations for care of the skin
    • A61Q19/004—Aftersun preparations
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q19/00—Preparations for care of the skin
    • A61Q19/04—Preparations for care of the skin for chemically tanning the skin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q19/00—Preparations for care of the skin
    • A61Q19/10—Washing or bathing preparations
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q5/00—Preparations for care of the hair
    • A61Q5/02—Preparations for cleaning the hair
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q5/00—Preparations for care of the hair
    • A61Q5/06—Preparations for styling the hair, e.g. by temporary shaping or colouring
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q5/00—Preparations for care of the hair
    • A61Q5/12—Preparations containing hair conditioners

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Epidemiology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Medicinal Chemistry (AREA)
  • Molecular Biology (AREA)
  • Biomedical Technology (AREA)
  • Dermatology (AREA)
  • Birds (AREA)
  • Cosmetics (AREA)
  • Peptides Or Proteins (AREA)
  • Pyrrole Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

Die Erfindung betrifft ein Verfahren zur Herstellung von keratinbindenden Effektormolekülen sowie Zwischenprodukte und Endprodukte des erfindungsgemäßen Verfahren und die Verwendung der erfindungsgemäß hergestellten keratinbindenden Effektormoleküle in Dermokosmetika. Ferner betrifft die Erfindung ein Verfahren zur Applikation von dermokosmetisch aktiven Wirkstoffen auf Haut und/oder Haar und ein Verfahren zur Steigerung der Verweildauer eines aktiven Wirkstoffes auf Haut und Haar.
PCT/EP2006/068470 2005-11-24 2006-11-15 Keratinbindende effektormoleküle und verfahren zu deren herstellung Ceased WO2007147445A2 (de)

Priority Applications (7)

Application Number Priority Date Filing Date Title
US12/094,833 US20090098076A1 (en) 2005-11-24 2006-11-15 Method For the Production of a Keratin-Binding Effector Molecule
MX2008006524A MX2008006524A (es) 2005-11-24 2006-11-15 Metodo para la produccion de una molecula efectora de union a queratina.
BRPI0618980A BRPI0618980A2 (pt) 2005-11-24 2006-11-15 métodos de produzir uma molécula efetora que liga queratina, de aplicar molécula efetoras dermocosmeticamente ativas à pele, cabelo e/ou unhas das mãos e unhas dos pés e de aumentar o tempo de residência de um ingrediente dermocosmeticamente ativo sobre a pele, cabelo e/ou unhas das mãos ou unhas dos pés, molécula efetora que liga queratina, uso de moléculas efetoras que ligam queratina, compostos e dermocosmético
CA002630903A CA2630903A1 (en) 2005-11-24 2006-11-15 Keratin-binding effector molecules, and method for the production thereof
EP06851524A EP1957111A2 (de) 2005-11-24 2006-11-15 Keratinbindende effektormoleküle und verfahren zu deren herstellung
AU2006344932A AU2006344932A1 (en) 2005-11-24 2006-11-15 Keratin-binding effector molecules, and method for the production thereof
JP2008541699A JP2009517361A (ja) 2005-11-24 2006-11-15 ケラチン結合エフェクター分子、およびその生成方法

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
EP05111218 2005-11-24
EP05111218.3 2005-11-24
EP06116386 2006-06-30
EP06116386.1 2006-06-30

Publications (2)

Publication Number Publication Date
WO2007147445A2 WO2007147445A2 (de) 2007-12-27
WO2007147445A3 true WO2007147445A3 (de) 2008-03-13

Family

ID=37907433

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/EP2006/068470 Ceased WO2007147445A2 (de) 2005-11-24 2006-11-15 Keratinbindende effektormoleküle und verfahren zu deren herstellung

Country Status (8)

Country Link
US (1) US20090098076A1 (de)
EP (1) EP1957111A2 (de)
JP (1) JP2009517361A (de)
AU (1) AU2006344932A1 (de)
BR (1) BRPI0618980A2 (de)
CA (1) CA2630903A1 (de)
MX (1) MX2008006524A (de)
WO (1) WO2007147445A2 (de)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN101855239B (zh) * 2007-06-20 2013-11-06 巴斯夫欧洲公司 合成的重复蛋白及其生产和用途
EP2042155A1 (de) * 2007-09-28 2009-04-01 Basf Se Verfahren zum Entfernen von wasserunlöslichen Substanzen von Substratoberflächen
WO2009112301A2 (de) * 2008-03-10 2009-09-17 Basf Se Polypeptidwirkstoffe in der form von konjugaten aus keratinbindenden polypeptiden, polymeren und effektormolekülen, verfahren zu ihrer herstellung und ihre verwendung
FR2932087B1 (fr) * 2008-06-10 2012-10-12 Oreal Utilisation cosmetique de proteines de type desmoplakine pour le traitement de la secheresse cutanee
WO2010010145A1 (en) * 2008-07-23 2010-01-28 Basf Se Keratin-binding polypeptides and method for their identification
JP5965619B2 (ja) * 2011-11-18 2016-08-10 株式会社ミルボン スプレー
US9672952B2 (en) 2013-08-14 2017-06-06 Industrial Technology Research Institute Polymer and conductive composition
KR20200143431A (ko) * 2018-04-13 2020-12-23 메사추세츠 인스티튜트 오브 테크놀로지 모발 복구 및 오래-지속되는 색 유지를 위한 조작된 트리트먼트

Citations (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB2241702A (en) * 1990-02-08 1991-09-11 Cird Galderma Antibodies binding to stratum corneum of the epidermis
JPH0429912A (ja) * 1990-05-25 1992-01-31 Takara Shuzo Co Ltd 新規化粧料
EP0634161A1 (de) * 1992-12-08 1995-01-18 Kanebo, Ltd. Haarfärbemittel oder kosmetische zusammensetzung, vorbehandlungsagent sowie verfahren zur haarfärbung
EP1470824A1 (de) * 2002-12-10 2004-10-27 L-MAbs B.V. Proteine mit hoher Affinität für kosmetische Substanzen mit gesteuerter Anwendung
WO2005115306A2 (de) * 2004-05-24 2005-12-08 Basf Aktiengesellschaft Keratin-bindende polypeptide
WO2006097432A2 (de) * 2005-03-14 2006-09-21 Basf Aktiengesellschaft Keratin-biktdende desmoplakinpolypeptidsequenzen
WO2006136607A2 (de) * 2005-06-24 2006-12-28 Basf Aktiengesellschaft Verwendung von hydrophobin-polypeptiden sowie konjugaten aus hydrophobin-polypeptiden mit wirk- oder effektstoffen und ihre herstellung sowie deren einsatz in der kosmetik
WO2007060116A2 (de) * 2005-11-24 2007-05-31 Basf Se Keratinbindende effektormoleküle und verfahren zu deren herstellung durch kopplung keratinbindender polypeptide mit carboxylgruppen oder sulfonsäuregruppen tragenden effektormolekülen

Patent Citations (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB2241702A (en) * 1990-02-08 1991-09-11 Cird Galderma Antibodies binding to stratum corneum of the epidermis
JPH0429912A (ja) * 1990-05-25 1992-01-31 Takara Shuzo Co Ltd 新規化粧料
EP0634161A1 (de) * 1992-12-08 1995-01-18 Kanebo, Ltd. Haarfärbemittel oder kosmetische zusammensetzung, vorbehandlungsagent sowie verfahren zur haarfärbung
EP1470824A1 (de) * 2002-12-10 2004-10-27 L-MAbs B.V. Proteine mit hoher Affinität für kosmetische Substanzen mit gesteuerter Anwendung
WO2005115306A2 (de) * 2004-05-24 2005-12-08 Basf Aktiengesellschaft Keratin-bindende polypeptide
WO2006097432A2 (de) * 2005-03-14 2006-09-21 Basf Aktiengesellschaft Keratin-biktdende desmoplakinpolypeptidsequenzen
WO2006136607A2 (de) * 2005-06-24 2006-12-28 Basf Aktiengesellschaft Verwendung von hydrophobin-polypeptiden sowie konjugaten aus hydrophobin-polypeptiden mit wirk- oder effektstoffen und ihre herstellung sowie deren einsatz in der kosmetik
WO2007060116A2 (de) * 2005-11-24 2007-05-31 Basf Se Keratinbindende effektormoleküle und verfahren zu deren herstellung durch kopplung keratinbindender polypeptide mit carboxylgruppen oder sulfonsäuregruppen tragenden effektormolekülen

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
FONTAO LIONEL ET AL: "INTERACTION OF THE BULLOUS PEMPHIGOID ANTIGEN 1 (BP230) AND DESMOPLAKIN WITH INTERMEDIATE FILAMENTS IS MEDIATED BY DISTINCT SEQUENCES WITHIN THEIR COOH TERMINUS", MOLECULAR BIOLOGY OF THE CELL, BETHESDA, MD, US, vol. 14, no. 5, May 2003 (2003-05-01), pages 1978 - 1992, XP009085452, ISSN: 1059-1524 *

Also Published As

Publication number Publication date
MX2008006524A (es) 2008-09-12
US20090098076A1 (en) 2009-04-16
EP1957111A2 (de) 2008-08-20
WO2007147445A2 (de) 2007-12-27
AU2006344932A1 (en) 2007-12-27
BRPI0618980A2 (pt) 2016-09-13
JP2009517361A (ja) 2009-04-30
CA2630903A1 (en) 2007-12-27

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