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WO2007007151A3 - Use of anti-mad-cam antibody for the treatment of emphysema - Google Patents

Use of anti-mad-cam antibody for the treatment of emphysema Download PDF

Info

Publication number
WO2007007151A3
WO2007007151A3 PCT/IB2006/001870 IB2006001870W WO2007007151A3 WO 2007007151 A3 WO2007007151 A3 WO 2007007151A3 IB 2006001870 W IB2006001870 W IB 2006001870W WO 2007007151 A3 WO2007007151 A3 WO 2007007151A3
Authority
WO
WIPO (PCT)
Prior art keywords
emphysema
treatment
mad
cam antibody
antibody
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Ceased
Application number
PCT/IB2006/001870
Other languages
French (fr)
Other versions
WO2007007151A2 (en
Inventor
Gary Craig Burgess
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Pfizer Ltd Great Britain
Original Assignee
Pfizer Ltd Great Britain
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Pfizer Ltd Great Britain filed Critical Pfizer Ltd Great Britain
Publication of WO2007007151A2 publication Critical patent/WO2007007151A2/en
Publication of WO2007007151A3 publication Critical patent/WO2007007151A3/en
Anticipated expiration legal-status Critical
Ceased legal-status Critical Current

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K16/00Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • C07K16/2803Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the immunoglobulin superfamily
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00Drugs for disorders of the respiratory system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K2039/505Medicinal preparations containing antigens or antibodies comprising antibodies

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Immunology (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Engineering & Computer Science (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pulmonology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Peptides Or Proteins (AREA)

Abstract

The invention relates to the use of an anti-MAdCAM antibody for the manufacture of a medicament for the treatment of emphysema. Methods of treatment for emphysema using a therapeutically effective amount of an anti-MAdCAM antibody are also included.
PCT/IB2006/001870 2005-07-11 2006-07-03 Use of anti-mad-cam antibody for the treatment of emphysema Ceased WO2007007151A2 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US69857705P 2005-07-11 2005-07-11
US60/698,577 2005-07-11

Publications (2)

Publication Number Publication Date
WO2007007151A2 WO2007007151A2 (en) 2007-01-18
WO2007007151A3 true WO2007007151A3 (en) 2007-05-18

Family

ID=37011975

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/IB2006/001870 Ceased WO2007007151A2 (en) 2005-07-11 2006-07-03 Use of anti-mad-cam antibody for the treatment of emphysema

Country Status (1)

Country Link
WO (1) WO2007007151A2 (en)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
USRE45847E1 (en) 2004-01-09 2016-01-19 Pfizer Inc. Antibodies to MAdCAM

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA2916283C (en) 2015-01-09 2024-07-02 Pfizer MADCAM ANTAGONIST DOSING REGIMEN
JP7160491B2 (en) 2017-07-14 2022-10-25 ファイザー インコーポレイティッド Antibodies against MAdCAM
WO2024249568A1 (en) 2023-05-30 2024-12-05 Paragon Therapeutics, Inc. Alpha4beta7 integrin antibody compositions and methods of use

Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1998006248A2 (en) * 1996-08-15 1998-02-19 Leukosite, Inc. HUMANIZED IMMUNOGLOBULIN REACTIVE WITH α4β7 INTEGRIN
EP1308726A1 (en) * 2001-11-05 2003-05-07 Warner-Lambert Company LLC Methods and compositions for screening modulators of integrins
WO2005067620A2 (en) * 2004-01-09 2005-07-28 Pfizer Inc. ANTIBODIES TO MAdCAM

Patent Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1998006248A2 (en) * 1996-08-15 1998-02-19 Leukosite, Inc. HUMANIZED IMMUNOGLOBULIN REACTIVE WITH α4β7 INTEGRIN
EP1308726A1 (en) * 2001-11-05 2003-05-07 Warner-Lambert Company LLC Methods and compositions for screening modulators of integrins
WO2005067620A2 (en) * 2004-01-09 2005-07-28 Pfizer Inc. ANTIBODIES TO MAdCAM

Non-Patent Citations (3)

* Cited by examiner, † Cited by third party
Title
BAZAN-SOCHA S ET AL: "Integrins in pulmonary inflammatory diseases.", CURRENT PHARMACEUTICAL DESIGN. 2005, vol. 11, no. 7, March 2005 (2005-03-01), pages 893 - 901, XP009072999, ISSN: 1381-6128 *
LAZAR ALEXANDRU C ET AL: "Matrix-assisted laser desorption/ionization mass spectrometry for the evaluation of the C-terminal lysine distribution of a recombinant monoclonal antibody.", RAPID COMMUNICATIONS IN MASS SPECTROMETRY : RCM 2004, vol. 18, no. 3, 2004, pages 239 - 244, XP009080137, ISSN: 0951-4198 *
LITTLE M ET AL: "Of mice and men: hybridoma and recombinant antibodies", IMMUNOLOGY TODAY, ELSEVIER PUBLICATIONS, CAMBRIDGE, GB, vol. 21, no. 8, 1 August 2000 (2000-08-01), pages 364 - 370, XP004215163, ISSN: 0167-5699 *

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
USRE45847E1 (en) 2004-01-09 2016-01-19 Pfizer Inc. Antibodies to MAdCAM
US9328169B2 (en) 2004-01-09 2016-05-03 Pfizer Inc. Human antibodies that bind human MAdCAM

Also Published As

Publication number Publication date
WO2007007151A2 (en) 2007-01-18

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