[go: up one dir, main page]

WO2007005594A3 - Procede destine a l'amination reductrice des aldehydes et cetones par le biais de la formation d'intermediaires de polyimine macrocycliques - Google Patents

Procede destine a l'amination reductrice des aldehydes et cetones par le biais de la formation d'intermediaires de polyimine macrocycliques Download PDF

Info

Publication number
WO2007005594A3
WO2007005594A3 PCT/US2006/025559 US2006025559W WO2007005594A3 WO 2007005594 A3 WO2007005594 A3 WO 2007005594A3 US 2006025559 W US2006025559 W US 2006025559W WO 2007005594 A3 WO2007005594 A3 WO 2007005594A3
Authority
WO
WIPO (PCT)
Prior art keywords
intermediates
aldehydes
formation
reductive amination
ketones via
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Ceased
Application number
PCT/US2006/025559
Other languages
English (en)
Other versions
WO2007005594A2 (fr
Inventor
Michael Leo Tulchinsky
Barry B Fish
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Dow Global Technologies LLC
Original Assignee
Dow Global Technologies LLC
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Dow Global Technologies LLC filed Critical Dow Global Technologies LLC
Priority to EP06774347A priority Critical patent/EP1902011B1/fr
Priority to DE602006007357T priority patent/DE602006007357D1/de
Priority to AT06774347T priority patent/ATE433952T1/de
Priority to JP2008519608A priority patent/JP5237800B2/ja
Priority to CA002612574A priority patent/CA2612574A1/fr
Priority to CN2006800235373A priority patent/CN101213167B/zh
Priority to US11/922,687 priority patent/US8586793B2/en
Priority to AU2006265918A priority patent/AU2006265918B2/en
Priority to BRPI0613818-7A priority patent/BRPI0613818A2/pt
Priority to MX2007016493A priority patent/MX2007016493A/es
Publication of WO2007005594A2 publication Critical patent/WO2007005594A2/fr
Publication of WO2007005594A3 publication Critical patent/WO2007005594A3/fr
Anticipated expiration legal-status Critical
Ceased legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C209/00—Preparation of compounds containing amino groups bound to a carbon skeleton
    • C07C209/24—Preparation of compounds containing amino groups bound to a carbon skeleton by reductive alkylation of ammonia, amines or compounds having groups reducible to amino groups, with carbonyl compounds
    • C07C209/26—Preparation of compounds containing amino groups bound to a carbon skeleton by reductive alkylation of ammonia, amines or compounds having groups reducible to amino groups, with carbonyl compounds by reduction with hydrogen
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C211/00—Compounds containing amino groups bound to a carbon skeleton
    • C07C211/43—Compounds containing amino groups bound to a carbon skeleton having amino groups bound to carbon atoms of six-membered aromatic rings of the carbon skeleton
    • C07C211/44—Compounds containing amino groups bound to a carbon skeleton having amino groups bound to carbon atoms of six-membered aromatic rings of the carbon skeleton having amino groups bound to only one six-membered aromatic ring
    • C07C211/49—Compounds containing amino groups bound to a carbon skeleton having amino groups bound to carbon atoms of six-membered aromatic rings of the carbon skeleton having amino groups bound to only one six-membered aromatic ring having at least two amino groups bound to the carbon skeleton
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C211/00—Compounds containing amino groups bound to a carbon skeleton
    • C07C211/43—Compounds containing amino groups bound to a carbon skeleton having amino groups bound to carbon atoms of six-membered aromatic rings of the carbon skeleton
    • C07C211/44—Compounds containing amino groups bound to a carbon skeleton having amino groups bound to carbon atoms of six-membered aromatic rings of the carbon skeleton having amino groups bound to only one six-membered aromatic ring
    • C07C211/49—Compounds containing amino groups bound to a carbon skeleton having amino groups bound to carbon atoms of six-membered aromatic rings of the carbon skeleton having amino groups bound to only one six-membered aromatic ring having at least two amino groups bound to the carbon skeleton
    • C07C211/50—Compounds containing amino groups bound to a carbon skeleton having amino groups bound to carbon atoms of six-membered aromatic rings of the carbon skeleton having amino groups bound to only one six-membered aromatic ring having at least two amino groups bound to the carbon skeleton with at least two amino groups bound to carbon atoms of six-membered aromatic rings of the carbon skeleton
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C2601/00—Systems containing only non-condensed rings
    • C07C2601/12—Systems containing only non-condensed rings with a six-membered ring
    • C07C2601/14—The ring being saturated
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
    • Y02P20/00—Technologies relating to chemical industry
    • Y02P20/50—Improvements relating to the production of bulk chemicals
    • Y02P20/582—Recycling of unreacted starting or intermediate materials

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
  • Macromolecular Compounds Obtained By Forming Nitrogen-Containing Linkages In General (AREA)
  • Polymers With Sulfur, Phosphorus Or Metals In The Main Chain (AREA)

Abstract

L'invention concerne des composés d'aldéhyde ou cétone comprenant plus d'un groupe carbonyle et aminés de manière réductrice aux fins de formation d'un composé d'amine de produit comprenant plus d'un groupe amino principal. Le composé d'aldéhyde ou cétone est mis à réagir avec le composé d'amine de produit, de manière à former un mélange de réaction renfermant un ou plusieurs intermédiaires. L'intermédiaire est ensuite aminé de manière réductrice afin de former le produit souhaité. Ce procédé permet de produire le produit souhaité à des rendements très élevés avec des niveaux faibles d'impuretés d'amine secondaire.
PCT/US2006/025559 2005-06-30 2006-06-29 Procede destine a l'amination reductrice des aldehydes et cetones par le biais de la formation d'intermediaires de polyimine macrocycliques Ceased WO2007005594A2 (fr)

Priority Applications (10)

Application Number Priority Date Filing Date Title
EP06774347A EP1902011B1 (fr) 2005-06-30 2006-06-29 Procede d'amination reductrice d'aldehydes et de cetones via la formation d'intermediaires de type polyimines macrocycliques
DE602006007357T DE602006007357D1 (de) 2005-06-30 2006-06-29 Verfahren zur reduktiven aminierung von aldehyden und ketonen durch die bildung von makrocyclischen polyimin-zwischenprodukten
AT06774347T ATE433952T1 (de) 2005-06-30 2006-06-29 Verfahren zur reduktiven aminierung von aldehyden und ketonen durch die bildung von makrocyclischen polyimin-zwischenprodukten
JP2008519608A JP5237800B2 (ja) 2005-06-30 2006-06-29 大環状ポリイミン（ｍａｃｒｏｃｙｃｌｉｃｐｏｌｙｉｍｉｎｅｓ）中間体の形成を介した、アルデヒドおよびケトンの還元性アミノ化方法
CA002612574A CA2612574A1 (fr) 2005-06-30 2006-06-29 Procede destine a l'amination reductrice des aldehydes et cetones par le biais de la formation d'intermediaires de polyimine macrocycliques
CN2006800235373A CN101213167B (zh) 2005-06-30 2006-06-29 通过形成大环聚亚胺中间物还原胺化醛和酮的方法
US11/922,687 US8586793B2 (en) 2005-06-30 2006-06-29 Process for the reductive amination of aldehydes and ketones via the formation of macrocyclic polyimine intermediates
AU2006265918A AU2006265918B2 (en) 2005-06-30 2006-06-29 Process for the reductive amination of aldehydes and ketones via the formation of macrocyclic polyimine intermediates
BRPI0613818-7A BRPI0613818A2 (pt) 2005-06-30 2006-06-29 método para aminar de modo redutivo um composto de partida de aldeìdo ou cetona, método, método para aminar de modo redutivo um composto dialdeìdo alicìclico ou dicetona alicìclica, e método contìnuo ou semicontìnuo para aminar de modo redutivo um composto de partida de aldeìdo ou cetona
MX2007016493A MX2007016493A (es) 2005-06-30 2006-06-29 Proceso para la aminacion reductora de aldehidos y cetonas a traves de la formacion de intermediarios macrociclicos de poliimina.

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US69548905P 2005-06-30 2005-06-30
US60/695,489 2005-06-30

Publications (2)

Publication Number Publication Date
WO2007005594A2 WO2007005594A2 (fr) 2007-01-11
WO2007005594A3 true WO2007005594A3 (fr) 2007-05-24

Family

ID=37478751

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/US2006/025559 Ceased WO2007005594A2 (fr) 2005-06-30 2006-06-29 Procede destine a l'amination reductrice des aldehydes et cetones par le biais de la formation d'intermediaires de polyimine macrocycliques

Country Status (14)

Country Link
US (1) US8586793B2 (fr)
EP (1) EP1902011B1 (fr)
JP (1) JP5237800B2 (fr)
KR (1) KR20080026197A (fr)
CN (1) CN101213167B (fr)
AT (1) ATE433952T1 (fr)
AU (1) AU2006265918B2 (fr)
BR (1) BRPI0613818A2 (fr)
CA (1) CA2612574A1 (fr)
DE (1) DE602006007357D1 (fr)
MX (1) MX2007016493A (fr)
TW (1) TW200710069A (fr)
WO (1) WO2007005594A2 (fr)
ZA (1) ZA200800825B (fr)

Families Citing this family (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA2672677C (fr) * 2006-12-15 2012-07-10 Dow Global Technologies Inc. Procede d'amination reductrice d'aldehydes et de cetones
US8236922B2 (en) 2008-07-31 2012-08-07 Dow Global Technologies Llc Polyamide polymer
EP2406212B1 (fr) * 2009-03-12 2013-05-15 Basf Se Procédé pour produire de l'hydroxyde de 1-adamantyl-triméthylammonium
CN102482198B (zh) * 2009-07-31 2016-06-15 陶氏环球技术有限责任公司 将还原性氨化反应溶剂和杂质与一种或多种脂肪族二胺分离的方法
WO2011014752A2 (fr) * 2009-07-31 2011-02-03 Dow Global Technologies Inc. Procédé de conversion d'amines cycliques aliphatiques en diamines aliphatiques
US9817997B2 (en) 2014-12-18 2017-11-14 Banjo, Inc. User-generated content permissions status analysis system and method
US10678815B2 (en) 2012-10-02 2020-06-09 Banjo, Inc. Dynamic event detection system and method
CN105189470A (zh) 2013-03-15 2015-12-23 赛格提斯公司 生产辛烷二酸、前体和衍生物的方法
CN111116528B (zh) * 2014-07-10 2023-08-01 罗地亚经营管理公司 生产芳香族伯二胺的方法
WO2017105985A1 (fr) * 2015-12-18 2017-06-22 Archer Daniels Midland Company Préparation d'isohexide-3,6-dicarbaldéhydes et d'isohexide-3,6-diméthanamines
CN105647111B (zh) * 2016-04-12 2017-10-10 吉林大学 一种通过亚胺键共价连接的聚亚胺复合材料及其制备方法
CN110981705B (zh) * 2019-11-12 2022-08-05 万华化学集团股份有限公司 一种制备环己烷二甲胺的方法

Citations (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4215073A (en) * 1978-06-03 1980-07-29 Ruhrchemie Aktiengesellschaft Process for the production of diamines
EP0394968A1 (fr) * 1989-04-25 1990-10-31 Union Carbide Chemicals And Plastics Company, Inc. Amination de carbonyles
US5041675A (en) * 1988-06-30 1991-08-20 Hoechst Aktiengesellschaft Process for preparing 3(4),8(9)-bis(aminomethyl)-tricyclo[5.2.1.02,6 ]d
US5055618A (en) * 1989-05-30 1991-10-08 Hoechst Aktiengesellschaft Process for the preparation of α,ω-diamines
JPH10130210A (ja) * 1996-10-29 1998-05-19 Kuraray Co Ltd ジアミンの製造方法
US6252121B1 (en) * 1999-07-27 2001-06-26 Union Carbide Chemicals & Plastics Technology Corporation Metal-ligand complex catalyzed processes

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2894038A (en) * 1956-02-24 1959-07-07 Exxon Research Engineering Co Preparation of bifunctional cycloalkanes
DE4010227A1 (de) * 1990-03-30 1991-10-02 Basf Ag Verfahren zur herstellung von 3-aminomethyl-3,5,5-trimethyl-cyclohexylamin
EP0839796B1 (fr) * 1996-11-04 2002-06-12 Bayer Ag Procédé pour la préparation de 1,4-bis(aminométhyl) cyclohexane
JP4101352B2 (ja) * 1997-05-14 2008-06-18 株式会社クラレ ジアミンの製造法
SG70081A1 (en) * 1997-05-14 2000-01-25 Kuraray Co Process for producing diamines
US7199240B2 (en) * 2002-12-11 2007-04-03 Merck & Co., Inc. Reductive alkylation of saturated cyclic amines
CA2672677C (fr) * 2006-12-15 2012-07-10 Dow Global Technologies Inc. Procede d'amination reductrice d'aldehydes et de cetones

Patent Citations (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4215073A (en) * 1978-06-03 1980-07-29 Ruhrchemie Aktiengesellschaft Process for the production of diamines
US5041675A (en) * 1988-06-30 1991-08-20 Hoechst Aktiengesellschaft Process for preparing 3(4),8(9)-bis(aminomethyl)-tricyclo[5.2.1.02,6 ]d
EP0394968A1 (fr) * 1989-04-25 1990-10-31 Union Carbide Chemicals And Plastics Company, Inc. Amination de carbonyles
US5055618A (en) * 1989-05-30 1991-10-08 Hoechst Aktiengesellschaft Process for the preparation of α,ω-diamines
JPH10130210A (ja) * 1996-10-29 1998-05-19 Kuraray Co Ltd ジアミンの製造方法
US6252121B1 (en) * 1999-07-27 2001-06-26 Union Carbide Chemicals & Plastics Technology Corporation Metal-ligand complex catalyzed processes

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
DATABASE WPI Week 199830, Derwent World Patents Index; AN 1998-343246, XP002421101 *

Also Published As

Publication number Publication date
KR20080026197A (ko) 2008-03-24
ATE433952T1 (de) 2009-07-15
MX2007016493A (es) 2008-03-10
CA2612574A1 (fr) 2007-01-11
AU2006265918B2 (en) 2011-03-31
WO2007005594A2 (fr) 2007-01-11
US20100222611A1 (en) 2010-09-02
AU2006265918A1 (en) 2007-01-11
TW200710069A (en) 2007-03-16
EP1902011B1 (fr) 2009-06-17
EP1902011A2 (fr) 2008-03-26
CN101213167A (zh) 2008-07-02
CN101213167B (zh) 2012-05-23
ZA200800825B (en) 2009-04-29
JP2009500342A (ja) 2009-01-08
JP5237800B2 (ja) 2013-07-17
US8586793B2 (en) 2013-11-19
DE602006007357D1 (de) 2009-07-30
BRPI0613818A2 (pt) 2011-02-15

Similar Documents

Publication Publication Date Title
TW200833646A (en) Improved process for the reductive amination of aldehydes and ketones
WO2007005594A3 (fr) Procede destine a l'amination reductrice des aldehydes et cetones par le biais de la formation d'intermediaires de polyimine macrocycliques
WO2008035212A3 (fr) Procédés de préparation de composés intermédiaires utiles pour la préparation de cinacalcet
WO2006092213A8 (fr) Pyrazolylcarboxanilides
WO2007053702A8 (fr) Synthese de nucleotides fluorescents photoclivables a modification 3'-o-allyl en quadrichromie et procedes associes
WO2008048990A3 (fr) Procédés d'obtention de compositions anti-oxydantes macro-moléculaires
MY142297A (en) Method for the production of formic acid
WO2010054988A3 (fr) Procédé d'élaboration de diamines cycliques
WO2009027249A3 (fr) Procédé pour produire des amines à partir de polyols
WO2008063794A3 (fr) Composés d'oxazolidinium et utilisation en tant qu'inhibiteurs d'hydrate
WO2008059223A3 (fr) Procédé pour la synthèse de chlorhydrate de moxifloxacine
WO2009021342A3 (fr) Nouveau procédé
TW200640914A (en) Novel processes for the preparation of a benzofuran
WO2007119116A3 (fr) Procede perfectionne de synthese et de preparations de sels de duloxetine
WO2006024387A3 (fr) Biphenyl-thiazol-carboxamides
WO2008073411A3 (fr) Procédé pour synthétiser du 3-hydroxyglutaronitrile
WO2007062370A3 (fr) Composes calcilytiques
WO2006074334A3 (fr) Identification de cibles d'arn au moyen d'helicases
WO2006020348A3 (fr) Polymorphes du chlorhydrate d'atomoxetine
IL186014A0 (en) Process for the preparation of 2-azabicyclo[3.3.0] octane-3-carboxylic acid derivatives
WO2008015133A3 (fr) Procédé de fabrication d'amidrazones
WO2008081635A1 (fr) Procédé de production d'un composé contenant de l'azote
WO2010059503A3 (fr) Procédés de fabrication de (r)-3-(2,3-dihydroxypropyl)-6-fluoro-5-(2-fluoro-4-iodophénylamino)-8-méthylpyrido[2,3-d]pyrimidine-4,7(3h,8h)-dione et de ses intermédiaires
WO2011066482A3 (fr) Synthèse chirale d'isoxazolines, composés d'isoxazoline et utilisations de ceux-ci
WO2008044153A3 (fr) Procédé de synthèse amélioré de rimonabant

Legal Events

Date Code Title Description
WWE Wipo information: entry into national phase

Ref document number: 200680023537.3

Country of ref document: CN

121 Ep: the epo has been informed by wipo that ep was designated in this application
ENP Entry into the national phase

Ref document number: 2612574

Country of ref document: CA

WWE Wipo information: entry into national phase

Ref document number: 2006265918

Country of ref document: AU

WWE Wipo information: entry into national phase

Ref document number: MX/a/2007/016493

Country of ref document: MX

WWE Wipo information: entry into national phase

Ref document number: 11922687

Country of ref document: US

Ref document number: 2006774347

Country of ref document: EP

ENP Entry into the national phase

Ref document number: 2008519608

Country of ref document: JP

Kind code of ref document: A

NENP Non-entry into the national phase

Ref country code: DE

ENP Entry into the national phase

Ref document number: 2006265918

Country of ref document: AU

Date of ref document: 20060629

Kind code of ref document: A

WWE Wipo information: entry into national phase

Ref document number: 1020087002333

Country of ref document: KR

WWE Wipo information: entry into national phase

Ref document number: 501/CHENP/2008

Country of ref document: IN

ENP Entry into the national phase

Ref document number: PI0613818

Country of ref document: BR

Kind code of ref document: A2

Effective date: 20071227