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WO2007095336A3 - Production of hiv - Google Patents

Production of hiv Download PDF

Info

Publication number
WO2007095336A3
WO2007095336A3 PCT/US2007/004049 US2007004049W WO2007095336A3 WO 2007095336 A3 WO2007095336 A3 WO 2007095336A3 US 2007004049 W US2007004049 W US 2007004049W WO 2007095336 A3 WO2007095336 A3 WO 2007095336A3
Authority
WO
WIPO (PCT)
Prior art keywords
hiv
production
methods
provides
antigen
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Ceased
Application number
PCT/US2007/004049
Other languages
French (fr)
Other versions
WO2007095336A2 (en
Inventor
Bjorn K Lydersen
Peter W Lowry
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Immune Response Corp
Original Assignee
Immune Response Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Immune Response Corp filed Critical Immune Response Corp
Publication of WO2007095336A2 publication Critical patent/WO2007095336A2/en
Anticipated expiration legal-status Critical
Publication of WO2007095336A3 publication Critical patent/WO2007095336A3/en
Ceased legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N7/00—Viruses; Bacteriophages; Compositions thereof; Preparation or purification thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/12—Viral antigens
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/12—Viral antigens
    • A61K39/21—Retroviridae, e.g. equine infectious anemia virus
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/51—Medicinal preparations containing antigens or antibodies comprising whole cells, viruses or DNA/RNA
    • A61K2039/525—Virus
    • A61K2039/5252—Virus inactivated (killed)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/555—Medicinal preparations containing antigens or antibodies characterised by a specific combination antigen/adjuvant
    • A61K2039/55511—Organic adjuvants
    • A61K2039/55561—CpG containing adjuvants; Oligonucleotide containing adjuvants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/555—Medicinal preparations containing antigens or antibodies characterised by a specific combination antigen/adjuvant
    • A61K2039/55511—Organic adjuvants
    • A61K2039/55566—Emulsions, e.g. Freund's adjuvant, MF59
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2740/00—Reverse transcribing RNA viruses
    • C12N2740/00011—Details
    • C12N2740/10011—Retroviridae
    • C12N2740/16011—Human Immunodeficiency Virus, HIV
    • C12N2740/16034—Use of virus or viral component as vaccine, e.g. live-attenuated or inactivated virus, VLP, viral protein

Landscapes

  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Virology (AREA)
  • Microbiology (AREA)
  • Immunology (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Mycology (AREA)
  • Genetics & Genomics (AREA)
  • Veterinary Medicine (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Organic Chemistry (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • Biochemistry (AREA)
  • Hematology (AREA)
  • Communicable Diseases (AREA)
  • General Engineering & Computer Science (AREA)
  • Biotechnology (AREA)
  • Biomedical Technology (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Peptides Or Proteins (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)

Abstract

The present invention provides methods for producing HIV and HIV antigen by propagating HIV, in particular HIV-I, in cells grown in chemically defined, protein free medium. The invention also provides HIV antigen produced by such methods.
PCT/US2007/004049 2006-02-15 2007-02-15 Production of hiv Ceased WO2007095336A2 (en)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
US77387706P 2006-02-15 2006-02-15
US60/773,877 2006-02-15
US81431806P 2006-06-16 2006-06-16
US60/814,318 2006-06-16

Publications (2)

Publication Number Publication Date
WO2007095336A2 WO2007095336A2 (en) 2007-08-23
WO2007095336A3 true WO2007095336A3 (en) 2008-10-16

Family

ID=38372138

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/US2007/004049 Ceased WO2007095336A2 (en) 2006-02-15 2007-02-15 Production of hiv

Country Status (2)

Country Link
US (1) US20080026448A1 (en)
WO (1) WO2007095336A2 (en)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2010122433A2 (en) 2009-04-22 2010-10-28 Koninklijke Philips Electronics N.V. Imaging measurement system with a printed organic photodiode array
CN110317832B (en) * 2018-03-28 2022-07-05 西比曼生物科技（香港）有限公司 Method for preparing purified preparation of recombinant lentiviral vector on GMP scale
CN110317791A (en) 2018-03-29 2019-10-11 西比曼生物科技（香港）有限公司 The method of GMP grades of serum free suspension cell large-scale production slow virus

Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5719050A (en) * 1993-12-24 1998-02-17 Eiken Chemical Co., Ltd. Animal cell culturing media containing N-acetyl-L-glutamic acid
US5736317A (en) * 1995-03-07 1998-04-07 Akzo Nobel N.V. Human T-cell line infected with HIV-2 which secretes a protein corresponding to native HIV-2 gp160 in an extracellular medium
US20050101011A1 (en) * 2003-09-18 2005-05-12 Tsao Mary C. Cell culture media
US20050170454A1 (en) * 2002-04-08 2005-08-04 David Mainwaring Cell culture medium

Patent Citations (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5719050A (en) * 1993-12-24 1998-02-17 Eiken Chemical Co., Ltd. Animal cell culturing media containing N-acetyl-L-glutamic acid
US5736317A (en) * 1995-03-07 1998-04-07 Akzo Nobel N.V. Human T-cell line infected with HIV-2 which secretes a protein corresponding to native HIV-2 gp160 in an extracellular medium
US5876732A (en) * 1995-03-07 1999-03-02 Akzo Nobel, N.V. Human T-cell line infected with HIV-2 which secretes functionally intact HIV-2 GP160
US20050170454A1 (en) * 2002-04-08 2005-08-04 David Mainwaring Cell culture medium
US20050101011A1 (en) * 2003-09-18 2005-05-12 Tsao Mary C. Cell culture media

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
DARFLER F.J.: "A Protein-Free Medium for the Growth of Hybridomas and other Cells of the Immune System", IN VITRO CELLULAR AND DEVELOPMENT BIOLOGY, vol. 26, no. 8, August 1990 (1990-08-01), pages 769 - 778, XP001147095 *

Also Published As

Publication number Publication date
US20080026448A1 (en) 2008-01-31
WO2007095336A2 (en) 2007-08-23

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