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WO2007088446A3 - A process and a reagent kit for the examination of the metabolic state related to the carbohydrate and lipid metabolism of a human organism - Google Patents

A process and a reagent kit for the examination of the metabolic state related to the carbohydrate and lipid metabolism of a human organism Download PDF

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Publication number
WO2007088446A3
WO2007088446A3 PCT/IB2007/000201 IB2007000201W WO2007088446A3 WO 2007088446 A3 WO2007088446 A3 WO 2007088446A3 IB 2007000201 W IB2007000201 W IB 2007000201W WO 2007088446 A3 WO2007088446 A3 WO 2007088446A3
Authority
WO
WIPO (PCT)
Prior art keywords
carbohydrate
examination
lipid metabolism
human organism
state related
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Ceased
Application number
PCT/IB2007/000201
Other languages
French (fr)
Other versions
WO2007088446A2 (en
Inventor
Attila Kolonics
Kalman Tory
Nagy Peter Literati
Laszlo Koranyi
Janos Egri
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
N-Gene Research Laboratories Inc
Original Assignee
N-Gene Research Laboratories Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by N-Gene Research Laboratories Inc filed Critical N-Gene Research Laboratories Inc
Publication of WO2007088446A2 publication Critical patent/WO2007088446A2/en
Publication of WO2007088446A3 publication Critical patent/WO2007088446A3/en
Anticipated expiration legal-status Critical
Ceased legal-status Critical Current

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Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/5005—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells
    • G01N33/5091—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells for testing the pathological state of an organism
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/68—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
    • G01N33/6893—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids related to diseases not provided for elsewhere
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2800/00—Detection or diagnosis of diseases
    • G01N2800/04—Endocrine or metabolic disorders

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Immunology (AREA)
  • Urology & Nephrology (AREA)
  • Hematology (AREA)
  • Biomedical Technology (AREA)
  • Chemical & Material Sciences (AREA)
  • Molecular Biology (AREA)
  • Medicinal Chemistry (AREA)
  • Physics & Mathematics (AREA)
  • Cell Biology (AREA)
  • Pathology (AREA)
  • Biotechnology (AREA)
  • Food Science & Technology (AREA)
  • General Physics & Mathematics (AREA)
  • Microbiology (AREA)
  • Analytical Chemistry (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Physiology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)

Abstract

The invention refers to a process for the examination of the metabolic state related to the carbohydrate and lipid metabolism of a human organism, thus, for the detection of the healthy or ill state. According to the invention, the number and/or one or more characteristics of the mitochondria that are present in the leukocyte cells separated from the blood sample of the individual to be examined and/or the amount of nitric oxide produced in the leucocyte cells are determined in a manner known per se, and, based on the values obtained, the state of the individual examined is evaluated.
PCT/IB2007/000201 2006-02-02 2007-01-30 A process and a reagent kit for the examination of the metabolic state related to the carbohydrate and lipid metabolism of a human organism Ceased WO2007088446A2 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
HUP0600082 2006-02-02
HU0600082A HUP0600082A2 (en) 2006-02-02 2006-02-02 Process and testset for examination of the metabolic state of the organism in connection with carbohydrate - and fatmetabolism

Publications (2)

Publication Number Publication Date
WO2007088446A2 WO2007088446A2 (en) 2007-08-09
WO2007088446A3 true WO2007088446A3 (en) 2007-11-29

Family

ID=89986557

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/IB2007/000201 Ceased WO2007088446A2 (en) 2006-02-02 2007-01-30 A process and a reagent kit for the examination of the metabolic state related to the carbohydrate and lipid metabolism of a human organism

Country Status (2)

Country Link
HU (1) HUP0600082A2 (en)
WO (1) WO2007088446A2 (en)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN111579763B (en) * 2020-04-09 2023-04-07 北京博瑞世安科技有限公司 Method for detecting respiratory function of leucocyte mitochondria and method for detecting kidney yin deficiency

Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
RU2021619C1 (en) * 1991-11-25 1994-10-15 Ирина Иосифовна Влох Method of insulin-resistance diagnosis in patients with depressive states
US6232078B1 (en) * 1997-02-21 2001-05-15 Hong-Kyu Lee Method for diagnosing preclinical diabetes by quantification of mitochondrial DNA in peripheral blood
US20030235812A1 (en) * 1999-04-30 2003-12-25 Mitokor Indicators of altered mitochondrial function in predictive methods for determining risk of type 2 diabetes mellitus

Patent Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
RU2021619C1 (en) * 1991-11-25 1994-10-15 Ирина Иосифовна Влох Method of insulin-resistance diagnosis in patients with depressive states
US6232078B1 (en) * 1997-02-21 2001-05-15 Hong-Kyu Lee Method for diagnosing preclinical diabetes by quantification of mitochondrial DNA in peripheral blood
US20030235812A1 (en) * 1999-04-30 2003-12-25 Mitokor Indicators of altered mitochondrial function in predictive methods for determining risk of type 2 diabetes mellitus

Non-Patent Citations (3)

* Cited by examiner, † Cited by third party
Title
DATABASE BIOSIS [online] BIOSCIENCES INFORMATION SERVICE, PHILADELPHIA, PA, US; June 2006 (2006-06-01), KOLONICS ATTILA ET AL: "Mitochondrial status of lymphocytes shows correlation with metabolic state", XP009087496, Database accession no. PREV200600669552 *
DIABETES, vol. 55, no. Suppl. 1, June 2006 (2006-06-01), 66TH ANNUAL MEETING OF THE AMERICAN-DIABETES-ASSOCIATION; WASHINGTON, DC, USA; JUNE 09 -13, 2006, pages A143 - A144, ISSN: 0012-1797 *
NAGY GYORGY ET AL: "Nitric oxide-dependent mitochondrial biogenesis generates Ca2+ signaling profile of lupus T cells", JOURNAL OF IMMUNOLOGY, vol. 173, no. 6, 15 September 2004 (2004-09-15), pages 3676 - 3683, XP002444870, ISSN: 0022-1767 *

Also Published As

Publication number Publication date
HUP0600082A2 (en) 2007-09-28
WO2007088446A2 (en) 2007-08-09
HU0600082D0 (en) 2006-03-28

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