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WO2007060525A3 - Process for preparing bicyclic pyrazolyl and imidazolyl compounds - Google Patents

Process for preparing bicyclic pyrazolyl and imidazolyl compounds Download PDF

Info

Publication number
WO2007060525A3
WO2007060525A3 PCT/IB2006/003314 IB2006003314W WO2007060525A3 WO 2007060525 A3 WO2007060525 A3 WO 2007060525A3 IB 2006003314 W IB2006003314 W IB 2006003314W WO 2007060525 A3 WO2007060525 A3 WO 2007060525A3
Authority
WO
WIPO (PCT)
Prior art keywords
imidazolyl compounds
preparing bicyclic
bicyclic pyrazolyl
pyrazolyl
preparing
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Ceased
Application number
PCT/IB2006/003314
Other languages
French (fr)
Other versions
WO2007060525A2 (en
Inventor
Janice Ethel Sieser
Robert Alan Singer
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Pfizer Products Inc
Original Assignee
Pfizer Products Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Pfizer Products Inc filed Critical Pfizer Products Inc
Publication of WO2007060525A2 publication Critical patent/WO2007060525A2/en
Publication of WO2007060525A3 publication Critical patent/WO2007060525A3/en
Anticipated expiration legal-status Critical
Ceased legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D498/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D498/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms in which the condensed system contains two hetero rings
    • C07D498/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00—Drugs for genital or sexual disorders; Contraceptives
    • A61P15/10—Drugs for genital or sexual disorders; Contraceptives for impotence
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
    • A61P25/16—Anti-Parkinson drugs
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/30—Drugs for disorders of the nervous system for treating abuse or dependence
    • A61P25/32—Alcohol-abuse
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/30—Drugs for disorders of the nervous system for treating abuse or dependence
    • A61P25/34—Tobacco-abuse
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/04—Anorexiants; Antiobesity agents

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Addiction (AREA)
  • Psychiatry (AREA)
  • Pain & Pain Management (AREA)
  • Reproductive Health (AREA)
  • Diabetes (AREA)
  • Hematology (AREA)
  • Psychology (AREA)
  • Hospice & Palliative Care (AREA)
  • Gynecology & Obstetrics (AREA)
  • Rheumatology (AREA)
  • Child & Adolescent Psychology (AREA)
  • Endocrinology (AREA)
  • Obesity (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)

Abstract

A process for preparing compounds of Formula (I) are described herein where A, B, R0a, R0b, R1a, R1b, n, m, X, R3a, R3b, and R4 are as defined herein. The crystalline form of 3-(4-chloro-phenyl)-2-(2-chloro-phenyl)-7-(2,2-difluoro-propyl)-6,7-dihydro-2H,5H-4-oxa-1,2,7-triaza-azulen-8-one which is prepared by this process is also described herein.
PCT/IB2006/003314 2005-11-28 2006-11-16 Process for preparing bicyclic pyrazolyl and imidazolyl compounds Ceased WO2007060525A2 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US74059005P 2005-11-28 2005-11-28
US60/740,590 2005-11-28

Publications (2)

Publication Number Publication Date
WO2007060525A2 WO2007060525A2 (en) 2007-05-31
WO2007060525A3 true WO2007060525A3 (en) 2007-10-04

Family

ID=38067595

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/IB2006/003314 Ceased WO2007060525A2 (en) 2005-11-28 2006-11-16 Process for preparing bicyclic pyrazolyl and imidazolyl compounds

Country Status (4)

Country Link
JP (1) JP2007145842A (en)
AR (1) AR057944A1 (en)
TW (1) TW200804398A (en)
WO (1) WO2007060525A2 (en)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2017140771A1 (en) 2016-02-18 2017-08-24 Syngenta Participations Ag Pesticidally active pyrazole derivatives
EP3606919A1 (en) 2017-04-05 2020-02-12 Syngenta Participations AG Pesticidally active pyrazole derivatives
US20200288713A1 (en) 2017-08-11 2020-09-17 Syngenta Participations Ag Pesticidally active pyrazole derivatives
US11252963B2 (en) 2017-08-11 2022-02-22 Syngenta Participations Ag Pesticidally active pyrazole derivatives
AR112673A1 (en) 2017-08-11 2019-11-27 Syngenta Participations Ag PYRAZOLE DERIVATIVES ACTIVE AS PESTICIDES
WO2020164994A1 (en) 2019-02-13 2020-08-20 Syngenta Crop Protection Ag Pesticidally active pyrazole derivatives

Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2005044822A1 (en) * 2003-11-07 2005-05-19 Pfizer Products Inc. Bicyclic pyrazolyl and imidazolyl compounds and uses thereof

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20050010592A1 (en) 2003-07-08 2005-01-13 John Guthrie Method and system for taking a data snapshot

Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2005044822A1 (en) * 2003-11-07 2005-05-19 Pfizer Products Inc. Bicyclic pyrazolyl and imidazolyl compounds and uses thereof

Also Published As

Publication number Publication date
AR057944A1 (en) 2007-12-26
WO2007060525A2 (en) 2007-05-31
JP2007145842A (en) 2007-06-14
TW200804398A (en) 2008-01-16

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