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WO2007053165A3 - Virus protein microarray and uses therefor - Google Patents

Virus protein microarray and uses therefor Download PDF

Info

Publication number
WO2007053165A3
WO2007053165A3 PCT/US2006/001018 US2006001018W WO2007053165A3 WO 2007053165 A3 WO2007053165 A3 WO 2007053165A3 US 2006001018 W US2006001018 W US 2006001018W WO 2007053165 A3 WO2007053165 A3 WO 2007053165A3
Authority
WO
WIPO (PCT)
Prior art keywords
protein microarray
virus protein
uses therefor
microarray
protein
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Ceased
Application number
PCT/US2006/001018
Other languages
French (fr)
Other versions
WO2007053165A2 (en
WO2007053165A9 (en
Inventor
Heng Zhu
Mike Snyder
Jian Wang
Guozhen Liu
Shaohui Hu
Ghil Jona
Xiaowei Zhu
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Yale University
Original Assignee
Yale University
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Yale University filed Critical Yale University
Publication of WO2007053165A2 publication Critical patent/WO2007053165A2/en
Publication of WO2007053165A9 publication Critical patent/WO2007053165A9/en
Anticipated expiration legal-status Critical
Publication of WO2007053165A3 publication Critical patent/WO2007053165A3/en
Ceased legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/005—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from viruses
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2770/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA ssRNA viruses positive-sense
    • C12N2770/00011—Details
    • C12N2770/20011—Coronaviridae
    • C12N2770/20022—New viral proteins or individual genes, new structural or functional aspects of known viral proteins or genes
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2333/00—Assays involving biological materials from specific organisms or of a specific nature
    • G01N2333/005—Assays involving biological materials from specific organisms or of a specific nature from viruses
    • G01N2333/08—RNA viruses
    • G01N2333/165—Coronaviridae, e.g. avian infectious bronchitis virus
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2469/00—Immunoassays for the detection of microorganisms
    • G01N2469/20—Detection of antibodies in sample from host which are directed against antigens from microorganisms
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2500/00—Screening for compounds of potential therapeutic value
    • G01N2500/04—Screening involving studying the effect of compounds C directly on molecule A (e.g. C are potential ligands for a receptor A, or potential substrates for an enzyme A)

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Biophysics (AREA)
  • Biochemistry (AREA)
  • Gastroenterology & Hepatology (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Medicinal Chemistry (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Virology (AREA)
  • Peptides Or Proteins (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)

Abstract

A virus protein micorarray that can serve as a rapid, sensitive and simple tool for identification of viral specific antibodies in sera, such as a SARS coronavirus protein microarray and methods of using the protein microarray.
PCT/US2006/001018 2005-01-11 2006-01-11 Virus protein microarray and uses therefor Ceased WO2007053165A2 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US64282405P 2005-01-11 2005-01-11
US60/642,824 2005-01-11

Publications (3)

Publication Number Publication Date
WO2007053165A2 WO2007053165A2 (en) 2007-05-10
WO2007053165A9 WO2007053165A9 (en) 2007-07-05
WO2007053165A3 true WO2007053165A3 (en) 2008-01-31

Family

ID=38006339

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/US2006/001018 Ceased WO2007053165A2 (en) 2005-01-11 2006-01-11 Virus protein microarray and uses therefor

Country Status (1)

Country Link
WO (1) WO2007053165A2 (en)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP2023142A1 (en) * 2007-07-30 2009-02-11 Mikrogen Molekularbiologische Entwicklungs-GmbH Immunoassay utilizing recombinant nucleocapsid-proteins for detection of antibodies to human coronaviruses
EP3058370A4 (en) * 2013-10-14 2017-08-30 The University of North Carolina at Chapel Hill Methods and compositions for coronavirus diagnostics and therapeutics
CN109734802A (en) * 2019-03-18 2019-05-10 扬州大学 A kind of preparation method of recombinant porcine epidemic diarrhea virus N, S protein monoclonal antibody
CN110273024A (en) * 2019-05-08 2019-09-24 广西大学 Fluorescence quantitative PCR detection primer and its kit based on Porcine epidemic diarrhea virus M gene
GB201910730D0 (en) * 2019-07-26 2019-09-11 Randox Teoranta Bovine Pathogen Array
CN111679083B (en) * 2020-02-17 2025-06-20 浙江大学医学院附属第一医院 Alkaline phosphatase protein chip kit for detecting novel coronavirus antibodies and preparation method thereof
CN111596064B (en) * 2020-04-28 2023-03-31 江苏省农业科学院 Rapid test card for simultaneously detecting PEDV and TGEV and preparation and use methods thereof
CN112067712B (en) * 2020-08-18 2022-11-01 上海纳米技术及应用国家工程研究中心有限公司 Volatile marker for diagnosing novel coronavirus and application thereof
TWI767434B (en) * 2020-12-01 2022-06-11 國立成功大學 Protein microarray, detection method thereof, use thereof and kit containing the same
US11175293B1 (en) 2021-01-04 2021-11-16 University Of Utah Research Foundation Rapid assay for detection of SARS-CoV-2 antibodies

Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2004096842A2 (en) * 2003-04-28 2004-11-11 Public Health Agency Of Canada Sars virus nucleotide and amino acid sequences and uses thereof
WO2005043111A2 (en) * 2003-07-14 2005-05-12 Ciphergen Biosystems, Inc. Serum biomarkers for sars

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2004096842A2 (en) * 2003-04-28 2004-11-11 Public Health Agency Of Canada Sars virus nucleotide and amino acid sequences and uses thereof
WO2005043111A2 (en) * 2003-07-14 2005-05-12 Ciphergen Biosystems, Inc. Serum biomarkers for sars

Non-Patent Citations (4)

* Cited by examiner, † Cited by third party
Title
CHEN ZELIANG ET AL: "Antigenicity analysis of different regions of the severe acute respiratory syndrome coronavirus nucleocapsid protein.", CLINICAL CHEMISTRY JUN 2004, vol. 50, no. 6, June 2004 (2004-06-01), pages 988 - 995, XP002450358, ISSN: 0009-9147 *
QIU M.F. ET AL: "Profile of Specific Antibodies to Individual Proteins of SARA-CoV and Antigenicity Analysis of Its Nucleocapsid Protein", MOLECULAR & CELLULAR PROTEOMICS, vol. 3, no. 10, October 2004 (2004-10-01), pages S273, XP002450355 *
QIU MAOFENG ET AL: "Antibody responses to individual proteins of SARS coronavirus and their neutralization activities.", MICROBES AND INFECTION / INSTITUT PASTEUR MAY 2005, vol. 7, no. 5-6, May 2005 (2005-05-01), pages 882 - 889, XP004936669, ISSN: 1286-4579 *
ZHU HENG ET AL: "Severe acute respiratory syndrome diagnostics using a coronavirus protein microarray.", PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA 14 MAR 2006, vol. 103, no. 11, 14 March 2006 (2006-03-14), pages 4011 - 4016, XP002450357, ISSN: 0027-8424 *

Also Published As

Publication number Publication date
WO2007053165A2 (en) 2007-05-10
WO2007053165A9 (en) 2007-07-05

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