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WO2007049304A3 - Stable coated pharmaceutical formulation of olanzapine and process for preparing the same - Google Patents

Stable coated pharmaceutical formulation of olanzapine and process for preparing the same Download PDF

Info

Publication number
WO2007049304A3
WO2007049304A3 PCT/IN2006/000430 IN2006000430W WO2007049304A3 WO 2007049304 A3 WO2007049304 A3 WO 2007049304A3 IN 2006000430 W IN2006000430 W IN 2006000430W WO 2007049304 A3 WO2007049304 A3 WO 2007049304A3
Authority
WO
WIPO (PCT)
Prior art keywords
olanzapine
preparing
same
pharmaceutical formulation
formulation
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Ceased
Application number
PCT/IN2006/000430
Other languages
French (fr)
Other versions
WO2007049304A2 (en
Inventor
Pavak Mehta
Piyush Gupta
Rajesh Bhaskar
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Jubilant Organosys Ltd
Original Assignee
Jubilant Organosys Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Jubilant Organosys Ltd filed Critical Jubilant Organosys Ltd
Publication of WO2007049304A2 publication Critical patent/WO2007049304A2/en
Publication of WO2007049304A3 publication Critical patent/WO2007049304A3/en
Anticipated expiration legal-status Critical
Ceased legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/28—Dragees; Coated pills or tablets, e.g. with film or compression coating
    • A61K9/2806—Coating materials
    • A61K9/2833—Organic macromolecular compounds
    • A61K9/284—Organic macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyvinyl pyrrolidone
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/55—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole
    • A61K31/551—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole having two nitrogen atoms, e.g. dilazep
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/28—Dragees; Coated pills or tablets, e.g. with film or compression coating
    • A61K9/2806—Coating materials
    • A61K9/282—Organic compounds, e.g. fats
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/28—Dragees; Coated pills or tablets, e.g. with film or compression coating
    • A61K9/2806—Coating materials
    • A61K9/2833—Organic macromolecular compounds
    • A61K9/286—Polysaccharides, e.g. gums; Cyclodextrin
    • A61K9/2866—Cellulose; Cellulose derivatives, e.g. hydroxypropyl methylcellulose
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2004—Excipients; Inactive ingredients
    • A61K9/2013—Organic compounds, e.g. phospholipids, fats
    • A61K9/2018—Sugars, or sugar alcohols, e.g. lactose, mannitol; Derivatives thereof, e.g. polysorbates

Landscapes

  • Health & Medical Sciences (AREA)
  • Epidemiology (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

Disclosed herein are stable solid coated oral formulations of olanzapine and the process of preparation thereof. The formulation comprising effective amount of olanazpine and pharmaceutically acceptable excipient, wherein said formulation is coated with stabilized coating employing a selective polymer selected from hydroxypropyl methyl cellulose phthalate, polyvinyl acetate phthalate, cellulose acetate phthalate, hydroxypropyl methyl cellulose acetate succinate, polyvinyl alcohol, vinyl acetate copolymer, pullulan gum or zein or in combination thereof.
PCT/IN2006/000430 2005-10-27 2006-10-27 Stable coated pharmaceutical formulation of olanzapine and process for preparing the same Ceased WO2007049304A2 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
IN2880DE2005 2005-10-27
IN2880/DEL/2005 2005-10-27

Publications (2)

Publication Number Publication Date
WO2007049304A2 WO2007049304A2 (en) 2007-05-03
WO2007049304A3 true WO2007049304A3 (en) 2007-07-26

Family

ID=37894365

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/IN2006/000430 Ceased WO2007049304A2 (en) 2005-10-27 2006-10-27 Stable coated pharmaceutical formulation of olanzapine and process for preparing the same

Country Status (1)

Country Link
WO (1) WO2007049304A2 (en)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2012153347A2 (en) * 2011-05-04 2012-11-15 Zentiva K.S. Oral pharmaceutical composition of olanzapine form 1

Citations (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0830858A1 (en) * 1996-09-24 1998-03-25 Eli Lilly And Company Formulation comprising coated olanzapine particles
US5919485A (en) * 1995-03-24 1999-07-06 Eli Lilly And Company Oral 2-methyl-thieno-benzodiazepine formulation
WO2001037816A2 (en) * 1999-11-23 2001-05-31 Biochemie Gesellschaft M.B.H. Coating of tablet cores
WO2004058222A1 (en) * 2002-12-20 2004-07-15 St. James Associates Llc/Faber Research Series High pressure compaction for pharmaceutical formulations
WO2005009407A2 (en) * 2003-07-29 2005-02-03 Ranbaxy Laboratories Limited Oral pharmaceutical formulations of olanzapine

Patent Citations (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5919485A (en) * 1995-03-24 1999-07-06 Eli Lilly And Company Oral 2-methyl-thieno-benzodiazepine formulation
EP0830858A1 (en) * 1996-09-24 1998-03-25 Eli Lilly And Company Formulation comprising coated olanzapine particles
WO2001037816A2 (en) * 1999-11-23 2001-05-31 Biochemie Gesellschaft M.B.H. Coating of tablet cores
WO2004058222A1 (en) * 2002-12-20 2004-07-15 St. James Associates Llc/Faber Research Series High pressure compaction for pharmaceutical formulations
WO2005009407A2 (en) * 2003-07-29 2005-02-03 Ranbaxy Laboratories Limited Oral pharmaceutical formulations of olanzapine

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
ANON.: "Oral pharmaceutical formulations for antipsychotic agent", IP.COM, vol. 3, no. 4, 2003, pages 60 - 61, XP013005932 *

Also Published As

Publication number Publication date
WO2007049304A2 (en) 2007-05-03

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